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Amphotericin B

27 Cited Publications
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Based on 27 publication(s) in Google Scholar

Amphotericin B is a polyene antifungal agent against a wide variety of fungal pathogens. It binds irreversibly to ergosterol, resulting in disruption of membrane integrity and ultimately cell death.

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  • Pureté: 93.31%
  • CAS No.: 1397-89-3
  • Formule: C47H73NO17
  • Masse moléculaire:924.08
  • Stockage:

    4°C, protect from light

    * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

  • Amphotericin B Chemical Structure
    Amphotericin B Chemical Structure
  • Experimental Validation Results for Amphotericin B
  • Experimental Validation Results for Amphotericin B
  • Experimental Validation Results for Amphotericin B
  • Experimental Validation Results for Amphotericin B
  • Experimental Validation Results for Amphotericin B
CAS No.: 1397-89-3
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  • Amphotericin B Chemical Structure
    Amphotericin B Chemical Structure
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    Amphotericin B purchased from MedChemExpress. Usage Cited in: Antioxidants (Basel). 2025 Aug 25;14(9):1046. [Abstract]

    Customer Validation
     Time–kill curves of C. albicans strains treated with AmB (MIC: 0.0625 μg/mL)-SXC and FLC-SXC combinations at fractional inhibitory concentration index (FICI) concentrations(Amphotericin B: AmB).

  • 1/16

    Amphotericin B purchased from MedChemExpress. Usage Cited in: Microbiol Spectr. 2023 Jun 15;11(3):e0530222. [Abstract]

    Customer Validation
     Changes in ROS generation ratio in Amphotericin B (1 μg/mL; 90 min) group. In flow cytometry analysis, the abscissa represents the relative fluorescence intensity, and the ordinate represents the spore count. The dark blue area represents the percentage of spores (P3) with emitted fluorescence after DHR-123 was oxidized. The peak value in the dark blue area indicates the largest number of oxidized spores under the corresponding fluorescence intensity.

  • 1/16

    Amphotericin B purchased from MedChemExpress. Usage Cited in: Microbiol Spectr. 2023 Jun 15;11(3):e0530222. [Abstract]

    Customer Validation
     Survival rates in mono-treatment and combination treatment groups. Note: The survival curves of larvae infected with E. dermatitidis after different interventions. Amphotericin B (AMB) (1 μg/mL) or AMB (0.25 μg/mL) combine with EVL can significantly improve the survival rate of larvae for 6 days.

  • 1/16

    Amphotericin B purchased from MedChemExpress. Usage Cited in: Front Cell Infect Microbiol. 2020 Jun 26;10:320. [Abstract]

    Customer Validation
     Kaplan-Meier survival plots of C. elegans infected by KU80△ in the presence of antifungal drugs. The glp-4(bn2); sek-1(km4) worms were pre-infected with KU80△ for 8 h then transferred into liquid killing media containing different concentrations of Amphotericin B (1-2 μg/mL; 0-72 h).

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    Amphotericin B purchased from MedChemExpress. Usage Cited in: Front Cell Infect Microbiol. 2020 Jun 26;10:320. [Abstract]

    Customer Validation
     Effect of antifungal treatment on Af293-dsRed infection to glp-4(bn2); sek-1(km4) worms. Images were taken under DIC and TRITC channels from DMSO treatment by 24 h, 1.5 μg/mL Amphotericin B (AmB) treatment by 48 h. Scale bar is 200 μm.

  • Amphotericin B