DLC-50
DLC-50 is a dual inhibitor for PARP-1 and HDAC-1 with IC50 of 1.2 nM and 31 nM. DLC-50 inhibits the proliferation of cancer cells MDA-MB-436, MDA-MB-231, and MCF-7 with IC50 of 0.3, 2.7 and 2.41 μM. DLC-50 induces apoptosis in MDA-MB-231, arrests the cell cycle at G2 phase.
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- CAS No.: 2928537-98-6
- 화학식: C28H32FN5O4S2
- 분자량:585.71
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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PARP1 1.2 nM (IC50) |
HDAC1 31 nM (IC50) |
Chemical Information
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CAS No. 2928537-98-6
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분자량 585.71
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화학식 C28H32FN5O4S2
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SMILES
O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(C(SCCCCCCC(NO)=O)=S)CC3)=O)=C2)C4=CC=CC=C41
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DLC-50 Related Classifications
HY-161868 Related Classifications
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