ASS234
Based on 1 Customer Validation
ASS234 is a potent monoamino oxidase (MAO) inhibitor with IC50s of 5.2 nM and 43 nM for MAO-A and MAO-B, respectively. ASS234 also inhibits AChE and BuChE with IC50s of 350 nM and 460 nM, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.6%
- No. CAS: 1334106-34-1
- Fòrmula: C29H37N3O
- Peso molecular:443.62
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Actividad biológica
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MAO-A 5.2 nM (IC50) |
MAO-B 43 nM (IC50) |
AChE 350 nM (IC50) |
BChE 460 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
0.38 μM
Compound: 5
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Inhibition of cerebral human recombinant AchE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition by Ellman's method
Inhibition of cerebral human recombinant AchE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition by Ellman's method
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[PMID: 22023459] |
| HEK293 | IC50 |
3.3 μM
Compound: II, ASS234
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Inhibition of recombinant human BuChE expressed in HEK293 cells preincubated for 15 mins
Inhibition of recombinant human BuChE expressed in HEK293 cells preincubated for 15 mins
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[PMID: 25418133] |
| HEK293 | IC50 |
3.4 μM
Compound: II, ASS234
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Inhibition of recombinant human AChE expressed in HEK293 cells preincubated for 15 mins
Inhibition of recombinant human AChE expressed in HEK293 cells preincubated for 15 mins
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[PMID: 25418133] |
Chemical Information
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No. CAS 1334106-34-1
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Appearance Solid
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Peso molecular 443.62
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Fòrmula C29H37N3O
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Color White to off-white
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SMILES
C#CCN(C)CC1=CC2=C(C=CC(OCCCC3CCN(CC3)CC4=CC=CC=C4)=C2)N1C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (263 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ASS234 Related Classifications
HY-121072 Related Classifications
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