DLC-50
DLC-50 is a dual inhibitor for PARP-1 and HDAC-1 with IC50 of 1.2 nM and 31 nM. DLC-50 inhibits the proliferation of cancer cells MDA-MB-436, MDA-MB-231, and MCF-7 with IC50 of 0.3, 2.7 and 2.41 μM. DLC-50 induces apoptosis in MDA-MB-231, arrests the cell cycle at G2 phase.
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- No. CAS: 2928537-98-6
- Fòrmula: C28H32FN5O4S2
- Peso molecular:585.71
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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PARP1 1.2 nM (IC50) |
HDAC1 31 nM (IC50) |
Chemical Information
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No. CAS 2928537-98-6
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Peso molecular 585.71
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Fòrmula C28H32FN5O4S2
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SMILES
O=C1NN=C(CC2=CC=C(F)C(C(N3CCN(C(SCCCCCCC(NO)=O)=S)CC3)=O)=C2)C4=CC=CC=C41
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DLC-50 Related Classifications
HY-161868 Related Classifications
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