PP144
PP144 is a kinase inhibitor that inhibits PI3K catalytic isoforms (p110α/β/δ/γ), mTOR, DNAPK, and multiple tyrosine kinases. PP144 can be used for the study of kinase function.
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- No. CAS: 1092788-73-2
- Fòrmula: C19H17N5O2
- Peso molecular:347.38
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
DNAPK 0.046 μM (IC50) |
p110γ 0.06 μM (IC50) |
p110δ 0.12 μM (IC50) |
p110α 0.344 μM (IC50) |
mTOR 0.426 μM (IC50) |
Src 0.525 μM (IC50) |
p110β 1.1 μM (IC50) |
Hck 1.1 μM (IC50) |
Abl 2 μM (IC50) |
VEGFR 14 μM (IC50) |
EphB4 18 μM (IC50) |
EGFR 100 μM (IC50) |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1092788-73-2
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Peso molecular 347.38
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Fòrmula C19H17N5O2
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SMILES
O=C1C=COC=2C=CC(=CC12)C3=NN(C=4N=CN=C(N)C34)C5CCCC5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PP144 Related Classifications
HY-134470 Related Classifications
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