Grp - gastrin releasing peptide Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 171101

Summary

Predicted to enable neuropeptide hormone activity. Involved in neuropeptide signaling pathway. Predicted to be located in secretory granule lumen. Predicted to be active in extracellular space. Orthologous to human GRP (Gastrin releasing peptide). [provided by Alliance of Genome Resources, Apr 2022]

Grp Products (1)

mRNA Protein Name
NM_133570.5 NP_598254.2 gastrin-releasing peptide preproprotein

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to sodium phosphate IEP
IEP: Inferred from expression pattern
32192106 RGD
involved in negative regulation of voltage-gated potassium channel activity IDA
IDA: Inferred from direct assay
33059246 RGD
involved in negative regulation of voltage-gated sodium channel activity IDA
IDA: Inferred from direct assay
33059246 RGD
involved in neuropeptide signaling pathway IMP
IMP: Inferred from mutant phenotype
12419521 RGD
involved in ossification IMP
IMP: Inferred from mutant phenotype
32192106 RGD
involved in positive regulation of vascular associated smooth muscle cell apoptotic process IMP
IMP: Inferred from mutant phenotype
32192106 RGD
involved in regulation of gene expression IMP
IMP: Inferred from mutant phenotype
32192106 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
32192106 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
32192106 RGD
is active in neuronal dense core vesicle IDA
IDA: Inferred from direct assay
2422591 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

gastrin-releasing peptide

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15785 Pimitespib Inhibitor 99.87% Unkown

Clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Phase
HY-15263 Retaspimycin Inhibitor / Phase 3
HY-147039 BOLD-100 free base / Phase 2
HY-15190 NVP-HSP990 99.49% Phase 1
HY-W250122 Glutamic acid sodium salt 99.92% Phase 1
HY-P0039 BIM-26226 Antagonist 98.73% Phase 1

Pre-clinical Phase

Bioactive Molecules (113)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0830 Palmitic acid Activator 99.86% Unkown
HY-10941 VER-155008 Inhibitor 99.82% Unkown
HY-N0830B Palmitic acid sodium Activator 95.0% Unkown
HY-N0830S6 Palmitic acid-13C16 Activator 99.72% Unkown
HY-100437 HA15 99.98% Unkown
HY-110188 BiP inducer X Inhibitor 99.62% Unkown
HY-18680 PU-WS13 Inhibitor 99.88% Unkown
HY-P0238 Gastrin-Releasing Peptide, human 99.41% Unkown
HY-N0830S2 Palmitic acid-d31 Activator 99.92% Unkown
HY-P0221C PACAP (1-38) free acid 99.94% Unkown
HY-10214 SNX-2112 99.49% Unkown
HY-138364 YUM70 98.01% Unkown
HY-N0830R Palmitic acid (Standard) Activator 98.31% Unkown
HY-N0830S9 Palmitic acid-13C Activator 98.0% Unkown
HY-112910 Grp94 Inhibitor-1 Inhibitor 98.75% Unkown
HY-132182 HPA-12 99.40% Unkown
HY-10210 Retaspimycin Hydrochloride Inhibitor 95.49% Yes
HY-125974 HM03 Inhibitor 99.51% Unkown
HY-N0830BS1 Palmitic acid-13C16 sodium Activator 99.1% Unkown
HY-N0830S5 Palmitic acid-d3 Activator 99.88% Unkown
HY-10942 VER-82576 Inhibitor 98.76% Unkown
HY-N2122 Neoisoliquiritin 99.74% Unkown
HY-155417 GPR34 receptor antagonist 3 99.88% Unkown
HY-162774A GRP75-IN-1 dihydrochloride Inducer 99.75% Unkown
HY-W020952 Palladium(Ⅱ) acetylacetonate 98.2% Unkown
HY-N0830S4 Palmitic acid-d2 Activator 99.8% Unkown
HY-N0830S3 Palmitic acid-1-13C Activator 99.87% Unkown
HY-N8439 Questiomycin A 99.00% Unkown
HY-50670 DGAT-1 inhibitor 2 95.33% Unkown
HY-152153 GRP78-IN-3 Inhibitor 99.88% Unkown
HY-N0830S7 Palmitic acid-d4 Activator 99.88% Unkown
HY-129692 Withanone Inhibitor 93.28% Unkown
HY-N0830S10 Palmitic acid-13C2 Activator 99.54% Unkown
HY-103544 [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P 99.75% Unkown
HY-117395 PU-H54 Inhibitor 99.04% Unkown
HY-155063 TRAP1-IN-1 Inhibitor 96.03% Unkown
HY-N2600 Kuwanon H 98.60% Unkown
HY-103277A BIM 23042 TFA Antagonist 99.75% Unkown
HY-N0830S12 Palmitic acid-d4-1 Activator 99.80% Unkown
HY-N0830S18 Palmitic acid-d1 Activator 99.90% Unkown
HY-N0830S Palmitic acid-1,2,3,4-13C4 Activator 99.9% Unkown
HY-P3112 ICI 216140 Antagonist 99.78% Unkown
HY-133735A GRP-60367 hydrochloride Inhibitor 99.41% Unkown
HY-103283 Neuromedin C (porcine) 98.29% Unkown
HY-P1185 Antagonist G 99.05% Unkown
HY-P3576A Biotin-Gastrin Releasing Peptide, human TFA / Unkown
HY-P10055A PSMA targeting peptide TFA 98.54% Unkown
HY-121845 4-Br-Bnlm Inhibitor 99.46% Unkown
HY-162767 KUNG65 Inhibitor 98.84% Unkown
HY-44154 PSB-CB5 98.3% Unkown
HY-N0830BS Palmitic acid-13C sodium Activator 98.0% Unkown
HY-N0830S20 Palmitic acid-d9 Activator 99.93% Unkown
HY-P10055 PSMA targeting peptide / Unkown
HY-W134007S1 Hexadecanoate-13C16 potassium Activator 98.40% Unkown
HY-119732 KUNG94 Inhibitor / Unkown
HY-103063 Iso-PU-H54 Inhibitor / Unkown
HY-103277 BIM 23042 Antagonist / Unkown
HY-103285 GRP (porcine) Activator / Unkown
HY-120800 KUNG29 Inhibitor / Unkown
HY-121723 PU-H39 Inhibitor / Unkown
HY-124221 Radamide / Unkown
HY-125974A HM03 trihydrochloride Inhibitor / Unkown
HY-145504 12-Dipalmitoyl-3-Linoelaidoyl-rac-glycerol / Unkown
HY-145540 1,2-Dipalmitoyl-3-Octanoyl-rac-glycerol / Unkown
HY-145857 GRP78-IN-1 / Unkown
HY-146420 GRP78-IN-2 Inhibitor / Unkown
HY-162768 Grp94 Inhibitor-2 Inhibitor / Unkown
HY-162774 GRP75-IN-1 Inducer / Unkown
HY-170818 Grp94 Inhibitor-3 Inhibitor / Unkown
HY-171992 COX-2-IN-55 99.20% Unkown
HY-175042 D-myo-Inositol-1,3,4,5,6-pentaphosphate ammonium salt Inhibitor 98% Unkown
HY-175865 HSP70-IN-7 / Unkown
HY-17674 Bombesin receptor antagonist-1 Antagonist / Unkown
HY-180195 Grp94-IN-3 Inhibitor / Unkown
HY-182360 Cytisine-platinum(IV) prodrug-1 / Unkown
HY-D2334 AlF-NOTA-c-d-VAP / Unkown
HY-N0830A Palmitic acid calcium Activator / Unkown
HY-N0830BS4 Palmitic acid-13C8 sodium Activator / Unkown
HY-N0830S1 Palmitic acid-15,15,16,16,16-d5 Activator / Unkown
HY-N0830S11 Palmitic acid-d2-1 Activator / Unkown
HY-N0830S13 Palmitic acid-d4-2 Activator / Unkown
HY-N0830S14 Palmitic acid-d17 Activator / Unkown
HY-N0830S15 Palmitic acid-d2-2 Activator / Unkown
HY-N0830S16 Palmitic acid-d2-3 Activator / Unkown
HY-N0830S17 Palmitic acid-d2-4 Activator / Unkown
HY-N0830S19 Palmitic acid-d2-5 Activator / Unkown
HY-N0830S21 Palmitic acid-d5 Activator / Unkown
HY-N0830S8 Palmitic acid-9,10-d2 Activator / Unkown
HY-N12656 Versipelostatin Inhibitor / Unkown
HY-N20674 Chalcomoracin / Unkown
HY-N2600R Kuwanon H (Standard) / Unkown
HY-P0221B PACAP (1-38) free acid TFA / Unkown
HY-P11031 CotH3 peptide Inhibitor / Unkown
HY-P11769 RM2 Antagonist / Unkown
HY-P1185A Antagonist G TFA / Unkown
HY-P3084 Human follicular gonadotropin releasing peptide / Unkown
HY-P3576 Biotin-Gastrin Releasing Peptide, human / Unkown
HY-P4689 Prolactin-Releasing Peptide (1-31) (rat) Activator / Unkown
HY-P5072 GRP (14-27) (human, porcine, canine) Agonist / Unkown
HY-RS05844 GRP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07612 LGALSL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07859 LSM4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15406 UCMA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W127458 Tin(II) palmitate Activator / Unkown
HY-W851050A BAP2 Inhibitor / Unkown
HY-121459 Neoantimycin Modulator / Unkown
HY-133735 GRP-60367 Inhibitor 98.23% Unkown
HY-N0830S22 Palmitic acid-13C-1 / Unkown
HY-RS16891 Grp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19968 Ucma Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23333 Grp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26471 Ucma Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W127601 Lard oil / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990805 Anti-Human/Mouse GRP78 Antibody (C38) Inhibitor 95.00% Unkown
HY-P990239 Anti-Human/Mouse GRP78 Antibody (N88) / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grp NCBI NCBI:2922