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製品番号: HY-121072

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ASS234

カスタマーレビュー

Based on 1 Customer Validation

ASS234 is a potent monoamino oxidase (MAO) inhibitor with IC₅₀s of 5.2 nM and 43 nM for MAO-A and MAO-B, respectively. ASS234 also inhibits AChE and BuChE with IC₅₀s of 350 nM and 460 nM, respectively.

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純度: 99.6%
CAS 番号: 1334106-34-1
分子式: C₂₉H₃₇N₃O
分子量:443.62

保管条件:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

ASS234 構造式

CAS 番号: 1334106-34-1

容量

価格（税別）

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数量

Amount: USD 0.00

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

IC₅₀ & Target^[1]

MAO-A

5.2 nM (IC₅₀)

MAO-B

43 nM (IC₅₀)

AChE

350 nM (IC₅₀)

BChE

460 nM (IC₅₀)

Monoamine Oxidase アイソフォーム固有の製品をすべて表示 :

MAO-A
MAO-B

Cholinesterase (ChE) アイソフォーム固有の製品をすべて表示 :

AChE
BChE

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	0.38 μM Compound: 5	Inhibition of cerebral human recombinant AchE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition by Ellman's method Inhibition of cerebral human recombinant AchE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition by Ellman's method	[PMID: 22023459]
HEK293	IC₅₀	3.3 μM Compound: II, ASS234	Inhibition of recombinant human BuChE expressed in HEK293 cells preincubated for 15 mins Inhibition of recombinant human BuChE expressed in HEK293 cells preincubated for 15 mins	[PMID: 25418133]
HEK293	IC₅₀	3.4 μM Compound: II, ASS234	Inhibition of recombinant human AChE expressed in HEK293 cells preincubated for 15 mins Inhibition of recombinant human AChE expressed in HEK293 cells preincubated for 15 mins	[PMID: 25418133]

化学情報

CAS 番号 1334106-34-1
性状 Solid
分子量 443.62
分子式 C₂₉H₃₇N₃O
Color White to off-white
SMILES

C#CCN(C)CC1=CC2=C(C=CC(OCCCC3CCN(CC3)CC4=CC=CC=C4)=C2)N1C
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (263 KB)
SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Anna Stasiak, et al. Effects of novel monoamine oxidases and cholinesterases targeting compounds on brain neurotransmitters and behavior in rat model of vascular dementia. Curr Pharm Des. 2014;20(2):161-71. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

生物活性
- 製品説明
- IC₅₀ & Target
化学情報
純度とドキュメンテーション
参考文献

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製品番号:
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ASS234

Neuronal Signaling Compound Library

Reprogramming Compound Library

Anti-Parkinson's Disease Compound Library

Neurodegenerative Disease-related Compound Library

Mitochondria-Targeted Compound Library

Antidepressant Compound Library

Metabolic Enzyme Compound Library

Membrane Protein-targeted Compound Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Alkyne Compound Library

Monoamine Oxidase アイソフォーム固有の製品をすべて表示

Cholinesterase (ChE) アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

ASS234

Neuronal Signaling Compound Library

Reprogramming Compound Library

Anti-Parkinson's Disease Compound Library

Neurodegenerative Disease-related Compound Library

Mitochondria-Targeted Compound Library

Antidepressant Compound Library

Metabolic Enzyme Compound Library

Membrane Protein-targeted Compound Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Alkyne Compound Library

Monoamine Oxidase アイソフォーム固有の製品をすべて表示

Cholinesterase (ChE) アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

ASS234 関連分類

HY-121072 関連分類