Dox-btn2
Based on 1 Customer Validation
Dox-btn2 is a biotin labeled Doxorubicin (HY-15142A), with a biotin label at the point of conjugation to doxorubicin at 3'-NH2. Dox-btn2 can be used for cell imaging. While Doxorubicin is mainly accumulated in the nucleus, while Dox-btn2 is mainly located in the cytoplasm.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.80%
- CAS 番号: 3026061-31-1
- 分子式: C48H64N4O18S
- 分子量:1017.10
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保管条件:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-15142A
DoxorubicinTopoisomerase Inhibitor
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生物活性
製品説明
体外実験
Dox-btn2 (1 μM; 6 h; Exc=531/40 nm and Emi=593/40 nm) exhibits visualization in U2OS cells, helps in situ mapping with Chem-map of small-molecule interactions with DNA and chromatin proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 3026061-31-1
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性状 Solid
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分子量 1017.10
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分子式 C48H64N4O18S
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Color Brown to orange
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SMILES
O=C1C2=C(O)C3=C([C@H](C[C@](C(CO)=O)(C3)O)O[C@H]4C[C@H](NC(CCOCCOCCOCCOCCNC(CCCC[C@H]5[C@@]6([H])NC(N[C@]6(CS5)[H])=O)=O)=O)[C@H](O)[C@H](C)O4)C(O)=C2C(C7=C1C=CC=C7OC)=O
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別名
Biotin Labeled Doxorubicin
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
溶剤 & 溶解度
体外:
DMSO : ≥ 50 mg/mL (49.16 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9832 mL | 4.9159 mL | 9.8319 mL | 24.5797 mL |
| 5 mM | 0.1966 mL | 0.9832 mL | 1.9664 mL | 4.9159 mL | |
| 10 mM | 0.0983 mL | 0.4916 mL | 0.9832 mL | 2.4580 mL | |
| 15 mM | 0.0655 mL | 0.3277 mL | 0.6555 mL | 1.6386 mL | |
| 20 mM | 0.0492 mL | 0.2458 mL | 0.4916 mL | 1.2290 mL | |
| 25 mM | 0.0393 mL | 0.1966 mL | 0.3933 mL | 0.9832 mL | |
| 30 mM | 0.0328 mL | 0.1639 mL | 0.3277 mL | 0.8193 mL | |
| 40 mM | 0.0246 mL | 0.1229 mL | 0.2458 mL | 0.6145 mL |
Dox-btn2 関連分類
HY-153797 関連分類
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