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Cat. No.: HY-121072

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ASS234

고객리뷰

Based on 1 Customer Validation

ASS234 is a potent monoamino oxidase (MAO) inhibitor with IC₅₀s of 5.2 nM and 43 nM for MAO-A and MAO-B, respectively. ASS234 also inhibits AChE and BuChE with IC₅₀s of 350 nM and 460 nM, respectively.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity: 99.6%
CAS No.: 1334106-34-1
화학식: C₂₉H₃₇N₃O
분자량:443.62

보관:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

ASS234 Chemical Structure

CAS No.: 1334106-34-1

사이즈

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재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

MAO-A

5.2 nM (IC₅₀)

MAO-B

43 nM (IC₅₀)

AChE

350 nM (IC₅₀)

BChE

460 nM (IC₅₀)

All Monoamine Oxidase Isoforms :

MAO-A
MAO-B

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	IC₅₀	0.38 μM Compound: 5	Inhibition of cerebral human recombinant AchE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition by Ellman's method Inhibition of cerebral human recombinant AchE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition by Ellman's method	[PMID: 22023459]
HEK293	IC₅₀	3.3 μM Compound: II, ASS234	Inhibition of recombinant human BuChE expressed in HEK293 cells preincubated for 15 mins Inhibition of recombinant human BuChE expressed in HEK293 cells preincubated for 15 mins	[PMID: 25418133]
HEK293	IC₅₀	3.4 μM Compound: II, ASS234	Inhibition of recombinant human AChE expressed in HEK293 cells preincubated for 15 mins Inhibition of recombinant human AChE expressed in HEK293 cells preincubated for 15 mins	[PMID: 25418133]

Chemical Information

CAS No. 1334106-34-1
Appearance Solid
분자량 443.62
화학식 C₂₉H₃₇N₃O
Color White to off-white
SMILES

C#CCN(C)CC1=CC2=C(C=CC(OCCCC3CCN(CC3)CC4=CC=CC=C4)=C2)N1C
선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Anna Stasiak, et al. Effects of novel monoamine oxidases and cholinesterases targeting compounds on brain neurotransmitters and behavior in rat model of vascular dementia. Curr Pharm Des. 2014;20(2):161-71. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
MCE Japan Authorized Agent:

상품명:
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ASS234

Neuronal Signaling Compound Library

Reprogramming Compound Library

Anti-Parkinson's Disease Compound Library

Neurodegenerative Disease-related Compound Library

Mitochondria-Targeted Compound Library

Antidepressant Compound Library

Metabolic Enzyme Compound Library

Membrane Protein-targeted Compound Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Alkyne Compound Library

All Monoamine Oxidase Isoforms

All Cholinesterase (ChE) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

ASS234

Neuronal Signaling Compound Library

Reprogramming Compound Library

Anti-Parkinson's Disease Compound Library

Neurodegenerative Disease-related Compound Library

Mitochondria-Targeted Compound Library

Antidepressant Compound Library

Metabolic Enzyme Compound Library

Membrane Protein-targeted Compound Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Alkyne Compound Library

All Monoamine Oxidase Isoforms

All Cholinesterase (ChE) Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

ASS234 Related Classifications

HY-121072 Related Classifications