Copy Link Print Information

Tauroursodeoxycholate

(Synonyms: Tauroursodeoxycholic acid; TUDCA; UR 906)
111 Cited Publications
Customer Review

Based on 111 publication(s) in Google Scholar

Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an orally active endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.

For research use only. We do not sell to patients.

  • Purity: 99.90%
  • CAS No.: 14605-22-2
  • Formula: C26H45NO6S
  • Molecular Weight:499.70
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Tauroursodeoxycholate Chemical Structure
    Tauroursodeoxycholate Chemical Structure
  • Experimental Validation Results for Tauroursodeoxycholate
  • Experimental Validation Results for Tauroursodeoxycholate
  • Experimental Validation Results for Tauroursodeoxycholate
  • Experimental Validation Results for Tauroursodeoxycholate
  • Experimental Validation Results for Tauroursodeoxycholate
  • Experimental Validation Results for Tauroursodeoxycholate
  • Experimental Validation Results for Tauroursodeoxycholate
  • Experimental Validation Results for Tauroursodeoxycholate
  • Experimental Validation Results for Tauroursodeoxycholate
  • Experimental Validation Results for Tauroursodeoxycholate
CAS No.: 14605-22-2
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Other Forms of Tauroursodeoxycholate:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Solvent & Solubility
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products

Publications Citing Use of MedChemExpress (MCE) Tauroursodeoxycholate

More
Customer Validation & Images
Histological Imaging/StainingIn Vivo Efficacy StudyWBRT-PCR
  • In Vivo Efficacy Study
  • Histological Imaging/Staining
  • RT-PCR
  • RT-PCR
  • WB
  • WB
  • WB
  • WB
  • WB
  • WB

All ERK Isoforms

More

All Caspase Isoforms

More

All Endogenous Metabolite Isoforms

More
Keywords
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • Tauroursodeoxycholate Chemical Structure
    Tauroursodeoxycholate Chemical Structure
    1/16
  • 1/16

    Tauroursodeoxycholate purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2026 Feb 9. [Abstract]

    Customer Validation
     RT-qPCR analysis of sXbp1, Cxcl10, and Ptprc (CD45) in cortices of mice with Tauroursodeoxycholate sodium (TUDCA, intraperitoneally at a dose of 50 mg/kg once daily) or saline administration at day 1 post-TBI.

  • 1/16

    Tauroursodeoxycholate purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Aug 16;16(1):7638. [Abstract]

    Customer Validation
     Representative images of mouse colon and H&E staining. Mice were treated with GUDCA or TUDCA (400 mg/kg, twice a week) after the AOM/DSS model was established (n = 8/group). H&E staining showed normal, dysplastic mucosae and carcinoma in the colon tissues.

  • 1/16

    Tauroursodeoxycholate purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Mar;12(12):e2411719. [Abstract]

    Customer Validation
     The mRNA levels of ALDOB in Huh7 or HCCLM3 cells treated with various bile acids (100 μM, 24 h). All data are presented as mean ± SD. Data were analyzed by one-way ANOVA with Bonferroni multiple-comparison correction. CA, cholic acid; TCA, taurocholic acid; GCA, glycocholic acid; TCDCA, taurochenodeoxycholic acid; GCDCA, glycochenodeoxycholic acid; LCA, lithocholic acid; TLCA, taurolithocholic acid; GLCA, glycolithocholic acid; DCA, deoxycholic acid; TDCA, taurodeoxycholic acid; GDCA, glycodeoxycholic acid; UDCA, ursodeoxycholic acid; TUDCA, tauroursodeoxycholic acid; GUDCA, glycoursodeoxycholic acid.

  • 1/16

    Tauroursodeoxycholate purchased from MedChemExpress. Usage Cited in: Nat Cell Biol. 2023 May;25(5):726-739. [Abstract]

    Customer Validation
     q-PCR analysis of ER stress markers in macrophages treated with vehicle or Tauroursodeoxycholate sodium (TUDCA) for 24 hr. n = 8 mice each, combined from 3 independent repeats.

  • 1/16

    Tauroursodeoxycholate purchased from MedChemExpress. Usage Cited in: Nat Cell Biol. 2023 May;25(5):726-739. [Abstract]

    Customer Validation
     Immunoblot of the STING pathway in macrophages pretreated with Tauroursodeoxycholate sodium (TUDCA) for 24 hr followed by DMXAA for another 1 hr. The numbers below the blot indicate relative band intensity of STING, p-STING (normalized to β-tubulin), or ratio of phosphorylated to total protein (p/t), representative of 2 independent repeats.

  • 1/16

    Tauroursodeoxycholate purchased from MedChemExpress. Usage Cited in: Mol Ther. 2023 Mar 1;31(3):890-908. [Abstract]

    Customer Validation
     Inhibition of ER stress by treatment with Tauroursodeoxycholate sodium (TUDCA, 100-500 nM, 24 h) prominently suppressed NLRP3 expression and the levels of active caspase-1 and IL-1β in MSC2D.

  • 1/16

    Tauroursodeoxycholate purchased from MedChemExpress. Usage Cited in: Mol Ther. 2023 Mar 1;31(3):890-908. [Abstract]

    Customer Validation
     MSC2D was treated with Tauroursodeoxycholate sodium (TUDCA, 100-500 nM) for 24 h.

  • 1/16

    Tauroursodeoxycholate purchased from MedChemExpress. Usage Cited in: BMC Mol Cell Biol. 2023 Mar 3;24(1):7. [Abstract]

    Customer Validation
     Tauroursodeoxycholate (TUDCA; 2 mM) not only suppresses the expression of RPL11-induced ERS-related proteins but also markedly mitigates the expression of LC3-II and BECN1 and increases the expression of p62 in RPL11-overexpressing NSCLC cells.

  • 1/16

    Tauroursodeoxycholate purchased from MedChemExpress. Usage Cited in: Biochem Pharmacol. 2018 Aug:154:278-292. [Abstract]

    Customer Validation
     TUDCA treatment inhibits the secretion of active IL-1β into cell culture media by Acetaminophen (APAP).

  • 1/16

    Tauroursodeoxycholate purchased from MedChemExpress. Usage Cited in: Fundam Clin Pharmacol. 2018 Aug;32(4):363-377. [Abstract]

    Customer Validation
     Effect of TUDCA and Fluoxetine on chronic unpredictable stress (CUS)-induced increase in Iba-1 protein expression in mice hippocampus and prefrontal cortex.

  • Tauroursodeoxycholate