1. Signaling Pathways
  2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. NLRP3 Isoform

NLRP3

 

NLRP3 Related Products (27):

Cat. No. Product Name Effect Purity
  • HY-100381
    Nigericin sodium salt
    Activator ≥98.0%
    Nigericin sodium salt is an antibiotic from Streptomyces hygroscopicus that works by acting as an H+, K+, and Pb2+ ionophore, a NLRP3 activator.
  • HY-116084
    Trimethylamine N-oxide
    Activator ≥98.0%
    Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients.
  • HY-N0633
    Muscone
    Inhibitor ≥98.0%
    Muscone is the main active monomer of traditional Chinese medicine musk.
  • HY-B0116
    Stavudine
    Inhibitor 99.67%
    Stavudine (d4T) is an orally active nucleoside reverse transcriptase inhibitor (NRTI).
  • HY-101092
    QS-21
    Activator
    QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant.
  • HY-150965
    NDT-30805
    Inhibitor
    NDT-30805 is a selective NLRP3 inflammasome inhibitor.
  • HY-151343
    NLRP3-IN-10
    Inhibitor
    NLRP3-IN-10 is a potent NLRP3 inhibitor, inhibits IL-1β release with an IC50 value of 251.1 nM.
  • HY-148187
    NLRP3-IN-11
    Inhibitor
    NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor.
  • HY-N0373
    Licochalcone B
    Inhibitor 99.93%
    Licochalcone B is an extract from the root of Glycyrrhiza uralensis.
  • HY-137245A
    Emlenoflast sodium
    Inhibitor 98.76%
    Emlenoflast (MCC7840) sodium, a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM.
  • HY-N0496
    Ruscogenin
    Inhibitor ≥98.0%
    Ruscogenin, an important steroid sapogenin derived from Ophiopogon japonicus, attenuates cerebral ischemia-induced blood-brain barrier dysfunction by suppressing TXNIP/NLRP3 inflammasome activation and the MAPK pathway and exerts significant anti-inflammatory and anti-thrombotic activities.
  • HY-16059
    Arglabin
    Inhibitor 99.87%
    Arglabin ((+)-Arglabin), a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor.
  • HY-139396
    BMS-986299
    Agonist 99.95%
    BMS-986299 (compound 112) is a first-in-class NLRP3 inflammasome agonist with an EC50 of 1.28 μM.
  • HY-N2485
    4'-Methoxyresveratrol
    Activator 99.70%
    4'-Methoxyresveratrol (4'-O-Methylresveratrol) is a polyphenol derived from Dipterocarpaceae, with antiandrogenic, antifungal and anti-inflammatory activities.
  • HY-130252
    YQ128
    Inhibitor 99.65%
    YQ128 is a potent and selective second-generation NLRP3 (NOD-like receptor P3) inflammasome inhibitor with an IC50 of 0.30 µM.
  • HY-100581
    CORM-3
    Inhibitor
    CORM-3, a carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels.
  • HY-122920
    Soyasaponin II
    Inhibitor 99.81%
    Soyasaponin II is a saponin with antiviral activity.
  • HY-131040
    NLRP3-IN-NBC6
    Inhibitor 99.40%
    NLRP3-IN-NBC6 is a potent, selective NLRP3 inflammasome inhibitor (IC50= 574 nM) that acts independently of Ca2+.
  • HY-121988
    INF4E
    Inhibitor 99.38%
    INF4E is a potent NLRP3 inflammasome inhibitor.
  • HY-137245
    Emlenoflast
    Inhibitor
    Emlenoflast (MCC7840), a sulfonylurea, is a potent and selective inhibitor of NLRP3 inflammasome, with an IC50 of <100 nM.