AP-24567
AP-24567 is a Ligands for Target Protein for PROTAC, which can be used for the synthesis of SB1-G-187 (HY-137342).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 943319-87-7
- Formule: C28H25F3N6O
- Masse moléculaire:518.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
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Lyn |
Yes |
IRAK1 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | IC50 |
34 nM
Compound: 20j
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Antiproliferative activity against mouse BA/F3 cells expressing ABL T315I mutant after 3 days by MTS assay
Antiproliferative activity against mouse BA/F3 cells expressing ABL T315I mutant after 3 days by MTS assay
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[PMID: 20513156] |
| BaF3 | IC50 |
4 nM
Compound: 20j
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Antiproliferative activity against mouse BA/F3 cells expressing wild type ABL after 3 days by MTS assay
Antiproliferative activity against mouse BA/F3 cells expressing wild type ABL after 3 days by MTS assay
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[PMID: 20513156] |
| BaF3 | IC50 |
915 nM
Compound: 20j
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Antiproliferative activity against mouse BA/F3 cells after 3 days by MTS assay
Antiproliferative activity against mouse BA/F3 cells after 3 days by MTS assay
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[PMID: 20513156] |
AP-24567 is a PROTAC-targeted protein ligand[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 943319-87-7
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Masse moléculaire 518.53
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Formule C28H25F3N6O
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SMILES
O=C(NC1=CC=C(CN2CCNCC2)C(C(F)(F)F)=C1)C3=CC=C(C)C(C#CC4=CN=C5C=CC=NN54)=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AP-24567 Related Classifications
HY-125142 Related Classifications
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