Cs - citrate synthase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 170587

Summary

Enables citrate (Si)-synthase activity. Involved in acetyl-CoA metabolic process; carboxylic acid metabolic process; and tricarboxylic acid cycle. Located in mitochondrion. Orthologous to human CS (citrate synthase). [provided by Alliance of Genome Resources, Apr 2022]

Cs Products (1)

mRNA Protein Name
NM_130755.1 NP_570111.1 citrate synthase, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables citrate (Si)-synthase activity IDA
IDA: Inferred from direct assay
818082 RGD
Biological Process GO Annotation Evidence References Source
involved in acetyl-CoA metabolic process IDA
IDA: Inferred from direct assay
818082 RGD
involved in citrate metabolic process IDA
IDA: Inferred from direct assay
818082 RGD
involved in heart development IEP
IEP: Inferred from expression pattern
14984324 RGD
involved in oxaloacetate metabolic process IDA
IDA: Inferred from direct assay
818082 RGD
involved in tricarboxylic acid cycle IDA
IDA: Inferred from direct assay
9712727 RGD
Cellular Component GO Annotation Evidence References Source
located in mitochondrion IDA
IDA: Inferred from direct assay
15809022 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

citrate synthase, mitochondrial

  • citrate (Si)-synthase

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-50935 Troglitazone 99.78% Unkown
HY-109015 Tucidinostat Inhibitor 98.74% Unkown
HY-B0165A Pravastatin sodium 99.38% Yes
HY-16276 Osilodrostat Inhibitor 99.90% Yes
HY-17005 Olmesartan medoxomil Inhibitor 98.95% Unkown
HY-B0023 Azelnidipine Inhibitor 99.79% Unkown
HY-100471 Esaxerenone Antagonist 99.93% Unkown
HY-16276A Osilodrostat phosphate Inhibitor 98.83% Yes
HY-N7101 Cefpodoxime Proxetil Inhibitor 98.93% Unkown
HY-B1595 Cefmetazole Inhibitor 98.82% Unkown
HY-14818A Laninamivir octanoate Inhibitor 98.57% Unkown
HY-B0165 Pravastatin / Unkown

Clinical Phase

Bioactive Molecules (17)
Cat. No. Product Name Effect
Purity Phase
HY-124526 Chiauranib Inhibitor 98.97% Phase 3
HY-100401 Pactimibe Inhibitor 99.98% Phase 3
HY-16445 Sapacitabine Chemical 98.69% Phase 3
HY-100401A Pactimibe sulfate Inhibitor 98.0% Phase 3
HY-141511 Coppersensor 1 ≥98.0% Phase 2
HY-160929 Linafexor Agonist 99.58% Phase 2
HY-14792B Inolitazone dihydrochloride Agonist 98.45% Phase 2
HY-116228 Cadrofloxacin Inhibitor 98.21% Phase 2
HY-14783 Apricoxib Inhibitor 98.84% Phase 2
HY-106888A CS-722 / Phase 2
HY-137005 CS1 / Phase 2
HY-14792 Inolitazone Agonist / Phase 2
HY-P6306A CS-6253 TFA 98.08% Phase 1
HY-100413 CS-526 Antagonist / Phase 1
HY-145995 CS12192 Inhibitor / Phase 1
HY-14976 CS-0777 Modulator / Phase 1
HY-19404 Embeconazole Inhibitor / Phase 1
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99758 Nofazinlimab Inhibitor 98.83% Phase 3
HY-P99270 Tigatuzumab Inducer 98.18% Phase 2

Pre-clinical Phase

Bioactive Molecules (84)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-B1692 L-Methionine-DL-sulfoximine Inhibitor ≥98.0% Unkown
HY-P6306 CS-6253 98.84% Unkown
HY-148907 CS640 Inhibitor 99.48% Unkown
HY-148913 CS587 Inhibitor 98.18% Unkown
HY-P2727 Chondroitinase ABC / Unkown
HY-P3522 REDV 99.33% Unkown
HY-B0165AR Pravastatin sodium (Standard) 98.10% Unkown
HY-W753658 Coppersensor-3 97.0% Unkown
HY-124704 Chst15-IN-1 Inhibitor 98.01% Unkown
HY-130086 Bis-​PEG4-​NHS ester 97.0% Unkown
HY-121447 Heneicosanoic acid 98.0% Unkown
HY-14955 Managlinat dialanetil Inhibitor 99.67% Unkown
HY-150611 EGFR-IN-70 Inhibitor 98.12% Unkown
HY-43962 CS-1-65 99.54% Unkown
HY-14180 PHA 408 Inhibitor 99.40% Unkown
HY-15801 HG-14-10-04 Inhibitor 99.09% Unkown
HY-17005R Olmesartan medoxomil (Standard) Inhibitor 99.35% Unkown
HY-50935S Troglitazone-d4 98.19% Unkown
HY-D0798 Catechol violet 90.0% Unkown
HY-P10948A CS-VIP 8 hydrochloride Inhibitor 96.04% Unkown
HY-105268 AzddMeC Inhibitor 98.96% Unkown
HY-106174 Lapisteride Inhibitor 99.0% Unkown
HY-106850 3′-Azido-2′,3′-dideoxyuridine Inhibitor 99.59% Unkown
HY-108493 CS-2100 Agonist 99.12% Unkown
HY-109015S Tucidinostat-d4 Inhibitor 98.63% Unkown
HY-111640 3'-Azido-3'-deoxy-5-methylcytidine Inhibitor 99.90% Unkown
HY-P1816 Fibronectin CS1 Peptide 99.10% Unkown
HY-P3522A REDV TFA 99.81% Unkown
HY-B0165CS Pravastatin-d3 sodium salt 99.02% Unkown
HY-Q51222 ZINC110492 Ligand 90.0% Unkown
HY-100471S Esaxerenone-d4 Antagonist / Unkown
HY-105114A Imitrodast sodium Inhibitor / Unkown
HY-106789 Plaunotol / Unkown
HY-106888 CS-722 Free base / Unkown
HY-123022 Tomopenem Inhibitor / Unkown
HY-128562 CS-1-69 / Unkown
HY-133606 3,4,5-Trichlorosyringol / Unkown
HY-143445 EGFR-IN-48 Inhibitor / Unkown
HY-14792C Inolitazone hydrochloride hydrate Agonist / Unkown
HY-14818C Laninamivir octanoate hydrate / Unkown
HY-148863 Cavα2δ1&NET-IN-2 Inhibitor / Unkown
HY-14977 CS-0777-P Agonist / Unkown
HY-15115 SUAM 1221 Inhibitor / Unkown
HY-159936 CS4 / Unkown
HY-163752 CS17919 Inhibitor / Unkown
HY-169247 Pam2CS-DMAPA / Unkown
HY-169427 FRF-06-057 Inhibitor / Unkown
HY-169982 EGFR-IN-136 Inhibitor / Unkown
HY-17005S Olmesartan medoxomil-d6 Inhibitor / Unkown
HY-171958 PROTAC EGFR degrader 12 Degrader / Unkown
HY-173132 AKR1Cs-IN-1 / Unkown
HY-175806 CS47 / Unkown
HY-178242 PROTAC EGFR degrader 16 Degrader / Unkown
HY-179238 CS-1-103 Inhibitor / Unkown
HY-182626 CS1P1 Antagonist / Unkown
HY-186232 CS-1-102 / Unkown
HY-186233 CS-1-174 Inhibitor / Unkown
HY-19633 CS-003 Free base Antagonist / Unkown
HY-19633A CS-003 / Unkown
HY-B0023S Azelnidipine-d7 Inhibitor / Unkown
HY-B0165AS Pravastatin-13C,d3 sodium / Unkown
HY-B0165S Pravastatin-d9 sodium / Unkown
HY-D3202 Lyso-CS2 / Unkown
HY-N7101S Cefpodoxime proxetil-d7 / Unkown
HY-P10797 TAT-N24 Inhibitor / Unkown
HY-P10948 CS-VIP 8 Inhibitor / Unkown
HY-P4021 Mca-KKEDVV-Abu-CS-Abu-S-(NO2)F-KK-NH2 / Unkown
HY-RS03221 CS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W743398 Mexazolam / Unkown
HY-W783351 CS790AM / Unkown
HY-107163 CS 461 Inhibitor / Unkown
HY-116228A Cadrofloxacin (hydrochloride) Inhibitor / Unkown
HY-138024 Tacapenem Inhibitor / Unkown
HY-14955A (Rac)-Managlinat dialanetil / Unkown
HY-174532 Human TGFB3 mRNA / Unkown
HY-175198 Cs-2d Inhibitor / Unkown
HY-175489 D-CS319 Inhibitor / Unkown
HY-178019 NDM-1-IN-10 Inhibitor / Unkown
HY-184611 Chitosan stabilized selenium nanoparticles / Unkown
HY-N7101S1 Cefpodoxime Proxetil-d6 Inhibitor / Unkown
HY-RS16750 Cs Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23189 Cs Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W667933 S-Propyl-L-cysteine sulfoxide / Unkown
HY-U00211 CS476 Inhibitor / Unkown
Bioactive MoleculesInhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992337 CS5001 Antibody Inhibitor / Unkown
HY-P992511 CS2009 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cs NCBI NCBI:1431