CS - citrate synthase Gene

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 1431

About CS

Cytogenetic location: 12q13.3 Genomic coordinates (GRCh38): 12:56,271,699-56,300,330 (from NCBI)

This gene has 33 transcripts (splice variants) and 237 orthologues. Ubiquitous expression in heart (RPKM 124.5), fat (RPKM 107.9) and 25 other tissues.

Summary

The protein encoded by this gene is a Krebs tricarboxylic acid cycle enzyme that catalyzes the synthesis of citrate from oxaloacetate and acetyl coenzyme A. The enzyme is found in nearly all cells capable of oxidative metablism. This protein is nuclear encoded and transported into the mitochondrial matrix, where the mature form is found. [provided by RefSeq, Jul 2008]

CS Products (1)

mRNA	Protein	Name
NM_004077.3	NP_004068.2	citrate synthase, mitochondrial precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Verweise	Source
enables citrate (Si)-synthase activity	IDA IDA: Inferred from direct assay	9543345	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	31141475	GOA

Biological Process GO Annotation	Evidence	Verweise	Source
involved in carbohydrate metabolic process	IDA IDA: Inferred from direct assay	9543345	GOA

Cellular Component GO Annotation	Evidence	Verweise	Source
located in mitochondrial matrix	IDA IDA: Inferred from direct assay	9543345	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CS Protein Structure

Citrate_synt

0
100
200
300
400
466 a.a.

Protein Preferred Names	Protein Names
citrate synthase, mitochondrial	citrate (Si)-synthase

Recombinant CS Proteins

Art. -Nr.	Produktname	Accession	Reinheit
HY-P74251	Citrate Synthase/CS Protein, Human (sf9, His)	O75390 (A28-G466)	≥ 90%, as determined by reducing SDS-PAGE.

CS Antibodies

Art. -Nr.	Produktname	Anwendung	Reactivity
HY-P83057	Citrate Synthetase Antibody (YA2802)	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Rat
HY-P83057A	Citrate Synthetase Antibody (YA2802)(PBS only)	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Rat

Related Diseases

Diseases	Alias
Queensland Tick Typhus	Australian Tick Typhus North Queensland Tick Typhus Rickettsia Australis Spotted Fever
Epidemic Typhus	Typhus Typhus Fever Epidemic Louse-Borne Typhus Fever Due To Rickettsia Prowazekii Murine Typhus Classical Typhus Endemic Flea-Borne Typhus Endemic Typhus Fever Epidemic Louse-Borne Typhus Famine Fever Flea-Borne Typhus Jail Fever Louse-Borne Typhus Mexican Typhus Shop Typhus Urban Typhus Brill-Zinsser Disease Endemic Typhus Sylvatic Typhus Epidemic Typhus European Typhus Exanthematic Typhus Fever Exanthematous Typhus Flea Typhus Flea-Borne Rickettsiosis Hospital Fever Louse-Borne [Epidemic] Typhus Louse-Borne Rickettsiosis Moscow Typhus Murine [Endemic] Typhus Petechial Fever Prison Fever Rat Flea Typhus Ship Fever Typhus Exanthematique Typhus, Endemic Flea-Borne Typhus, Epidemic Louse-Borne Typhus Group Rickettsial Disease Relapsing Fever Typhus Fever Nos Typhus Nos Epidemic Typhus Fever Louse-Borne Typhus Fever Classical Typhus Fever Louse-Borne Tabardillo Epidemic Typhus Fever Due To Rickettsia Prowazekii Endemic Murine Typhus Flea-Borne Typhus Fever Murine Endemic Flea Typhus Rat Typhus Typhus Due To Rickettsia Typhi Flea-Borne Tabardillo Rickettsia Typhi Rickettsiosis Mexican Fever Murine Flea-Borne Typhus Mooser Bodies Tsutsugamushi Fever Kedani Fever Mite-Borne Typhus Mite-Borne Typhus Due To Rickettsia Tsutsugamushi Scrub Typhus Tsutsugamushi Tsutsugamushi Disease Scrub Mite-Borne Typhus Sumatran Mite Fever Japanese River Fever Kedani Typhus Rickettsia Tsutsugamushi Rickettsiosis Sumatran Mite Typhus Tropical Typhus Japanese Typhus
African Tick-Bite Fever	Rickettsia Africae Spotted Fever South African Tick-Bite Fever African Tick Bite Fever
Indian Tick Typhus
Trench Fever	His-Werner Disease Quintan Fever Shin Bone Fever Wolhynian Fever Tibialgic Fever Bartonellosis Due To Bartonella Quintana Infection Febris Quintata Five Day Fever Fever Due To Rickettsia Quintana Febris Quintana Fever Due To Bartonella Quintana Fever Due To Rochalimaea Quintana Meuse Fever
Rocky Mountain Spotted Fever	Brazillian Spotted Choix Exanthematic Typhus Of Sao Paulo Fiebre Maculosa Fiebre Manchada Sao Paulo Typhus So Paulo Fever Tick Typhus Tobia Fever Rmsf Typhus, Tick
Israeli Tick Typhus	Israeli Spotted Fever
Cat-Scratch Disease	Cat Scratch Disease Benign Lymphoreticulosis Cat Scratch Fever Debre'S Syndrome Bartonellosis Due To Bartonella Henselae Infection Debre-Mollaret Syndrome Foshay-Mollaret Cat Scratch Fever Oroya Fever Cat-Scratch Fever Benign Inoculation Lymphoreticulosis Catscratch Disease Or Fever Csd - [Cat Scratch Disease] Nonbacterial Regional Lymphadenitis Rochalimaea Henselae Infection
Bartonellosis	Bartonella Infections Bartonella Infectious Disease Bartonelliasis Rochalimaea Infection Bartonellosis, Unspecified
Spotted Fever	Spotted Fevers Spotted Fever Group Rickettsial Disease Tick-Borne Rickettsioses Tick-Borne Typhus Nos Rocky Mountain Spotted Fever Sao Paulo Fever Sao Paulo Typhus Lone Star Spotted Fever Colombian Spotted Fever American Spotted Fever Tick Typhus Due To Rickettsia Rickettsii Rocky Mountain Tick Fever Boutonneuse Fever Mediterranean Tick Fever Fièvre Boutonneuse Mediterranean Spotted Fever Tick Typhus Due To Rickettsia Conorii African Tick Typhus Indian Tick Typhus Kenya Tick Typhus North Asian Tick Fever Siberian Tick Typhus Tick Typhus Due To Rickettsia Siberica North Asian Spotted Fever Queensland Tick Typhus Queensland Fever
Carrion'S Disease	Oroya Fever Carrion Disease Bartonellosis Due To Bartonella Bacilliformis Infection Bartonella Infections Systemic Bartonellosis Due To Bartonella Bacilliformis Systemic Carrión Disease Systemic Bartonellosis Bartonella Fever
Endemic Typhus	Murine Typhus Cat Flea Rickettsiosis Fleaborne Typhus Rat-Flea Typhus Rickettsia Felis Spotted Fever Shop Typhus Toulon Typhus Urban Typhus Urban Typhus Of Malaya Flea-Borne Typhus Endemic Flea-Borne Typhus
Type 2 Diabetes Mellitus	Insulin Resistance NIDDM Type 2 Diabetes Diabetes Mellitus, Non-Insulin-Dependent T2D Noninsulin-Dependent Diabetes Mellitus Diabetes Mellitus, Type Ii Maturity-Onset Diabetes Insulin Resistance, Severe, Digenic Diabetes Mellitus, Type 2 Diabetes Mellitus, Noninsulin-Dependent Diabetes Mellitus, Noninsulin-Dependent, Association With Diabetes Mellitus, Noninsulin-Dependent, Late Onset Hypertension, Insulin Resistance-Related, Susceptibility To Insulin Resistance, Susceptibility To Non-Insulin-Dependent Diabetes Mellitus Type Ii Diabetes Mellitus Adult-Onset Diabetes Mellitus Maturity-Onset Diabetes Mellitus Diabetes Mellitus Type 2 Type Ii Diabetes Type 2 Diabetes Mellitus, Susceptibility To Diabetes, Type 2 Diabetes Mellitus, Noninsulin-Dependent, Susceptibility To Diabetes Mellitus, Non-Insulin-Dependent, Susceptibility To Diabetes Mellitus, Type 2, Susceptibility To Diabetes Mellitus, Noninsulin-Dependent, 2 Diabetes Mellitus, Type Ii, Susceptibility To Hypertension, Insulin Resistance-Related Adult-Onset Diabetes Aodm Diabetes Mellitus, Adult-Onset Diabetes Mellitus Type Ii Diabetes Mellitus Type 2, Susceptibility To Diabetes, Type Ii, Susceptibility To Diabetes Type 2 Diabetes Mellitus Adult Onset Diabetes Maturity Onset Diabetes Nonketotic Diabetes Non-Insulin Dependent Diabetes Mellitus T2dm - [Type 2 Diabetes Mellitus] Niddm - [Non Insulin Dependent Diabetes Mellitus] Dm2 Dm Type Ii Diabetic Type 2 Insulin Requiring Type 2 Diabetes Noninsulin Dependent Diabetes Non-Insulin-Dependent Diabetes Mellitus Without Complications Diabetes Due To Insulin Secretory Defect Diabetes Mellitus Due To Insulin Secretory Defect Non-Insulin-Dependent Diabetes Of The Young Senile Diabetes Nonketotic Hyperglycaemia Stable Diabetes
Glycogen Storage Disease	Glycogenosis Glycogenoses Gsd Storage Disease, Glycogen Gsd - [Glycogen Storage Disease] Glycogen Thesaurismosis Diffuse Glycogenosis Generalised Glycogen Storage Disease Generalised Glycogenosis Generalised Glycogen Storage Disease Of Infants Glycogen Synthase Deficiency
Combined Oxidative Phosphorylation Deficiency 33	COXPD33
Heart Disease	Heart Failure Congenital Heart Disease Heart Diseases Congenital Heart Defects Congenital Heart Defect Heart Malformation Congenital Anomaly Of Heart Heart Defect Heart-Congenital Defect Congenital Heart Disorder Heart Defects Congenital Heart Defects, Congenital Heart Defects Heart Disease, Congenital Disease, Heart, Congenital Congestive Heart Failure
Boutonneuse Fever	Mediterranean Spotted Fever African Tick Typhus Boutonneuse Disease Conor And Bruch'S Disease Kenya Fever Kenya Tick Typhus Kenyan Tick Typhus Marseilles Fever Mediterranean Tick Fever Rickettsia Conorii Spotted Fever South African Tick-Bite Fever African Tick Bite Fever
Cardiac Arrest	Cardiopulmonary Arrest Circulatory Arrest Heart Arrest
Japanese Spotted Fever	Oriental Spotted Fever Rickettsia Japonica Spotted Fever
Myopathy	Muscular Diseases Myopathies
Cataract 38	CTRCT38 Catc5 Autosomal Recessive Congenital Cataract 5 Cataract, Autosomal Recessive Congenital 5 Cataract 38, Autosomal Recessive Cataract, Type 38
Spastic Paraplegia 38, Autosomal Dominant	SPG38 Hereditary Spastic Paraplegia 38 Autosomal Dominant Spastic Paraplegia Type 38 Autosomal Dominant Spastic Paraplegia 38
Human Granulocytic Anaplasmosis	Human Granulocytic Ehrlichiosis Hge Human Ehrlichial Infection, Human Granulocytic Type Human Anaplasmosis Due To Anaplasma Phagocytophilum
Muscular Atrophy	Muscle Wasting Amyotrophia Wasting - Muscle Skeletal Muscle Atrophy
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy
Pediculus Humanus Corporis Infestation	Body Louse Infestation Pediculus Corporis Pediculus Humanus Infestation
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Neuromuscular Disease	Neuromuscular Diseases Neuromuscular Disorders Neuromuscular Disorder
Kearns-Sayre Syndrome	Ophthalmoplegia Mitochondrial Cytopathy KSS Ophthalmoplegia, Pigmentary Degeneration Of Retina, And Cardiomyopathy Oculocraniosomatic Syndrome Chronic Progressive External Ophthalmoplegia With Myopathy Cpeo With Myopathy Total Ophthalmoplegia Ophthalmoplegia-Plus Syndrome Ophthalmoplegia, Progressive External, With Ragged-Red Fibers Cpeo With Ragged-Red Fibers Oculomotor Paralysis Renal Tubulopathy, Diabetes Mellitus, And Cerebellar Ataxia Due To Duplication O Renal Tubulopathy, Diabetes Mellitus, And Cerebellar Ataxia Due To Duplication Of Mitochondrial Dna Proximal Tubulopathy, Diabetes Mellitus And Cerebellar Ataxia Cpeo With Ragged Red Fibers Ophthalmoplegia Plus Syndrome Ophthalmoplegia, Progressive External, With Ragged Red Fibers Kearns-Sayre Mitochondrial Cytopathy Mitochondrial Myopathies
Mitochondrial Complex I Deficiency, Nuclear Type 1	Mitochondrial Complex I Deficiency Nadh:Q(1) Oxidoreductase Deficiency MC1DN1 Nadh-Coenzyme Q Reductase Deficiency Isolated Mitochondrial Respiratory Chain Complex I Deficiency Isolated Nadh-Coenzyme Q Reductase Deficiency Isolated Nadh-Coq Reductase Deficiency Isolated Nadh-Ubiquinone Reductase Deficiency Mitochondrial Nadh Dehydrogenase Component Of Complex I, Deficiency Of Nuclear Type Mitochondrial Complex I Deficiency 1 Isolated Complex I Deficiency Complex 1 Mitochondrial Respiratory Chain Deficiency Nadh Coenzyme Q Reductase Deficiency Complex I Mitochondrial Respiratory Chain Deficiency Deficiency Of Mitochondrial Nadh Dehydrogenase Component Of Complex I Nadh:Ubiquinone Oxidoreductase Deficiency Complex I, Mitochondrial Respiratory Chain, Deficiency Of
3-Methylglutaconic Aciduria, Type Iii	Optic Atrophy 3-Methylglutaconic Aciduria Type 3 Costeff Syndrome Mga3 Costeff Optic Atrophy Syndrome Optic Atrophy Plus Syndrome Infantile Optic Atrophy With Chorea And Spastic Paraplegia 3-Methylglutaconic Aciduria Type Iii Autosomal Recessive Optic Atrophy Plus Syndrome Autosomal Recessive Optic Atrophy Type 3 Opa3 Defect MGCA3 Mga, Type Iii Iraqi Jewish Optic Atrophy Plus Mga Type Iii Optic Atrophy, Infantile, With Chorea And Spastic Paraplegia Iraqi-Jewish 'Optic Atrophy Plus' Optic Atrophy 3, Autosomal Recessive Opa3, Autosomal Recessive Opa3-Related 3-Methylglutaconic Aciduria Iraqi-Jewish Optic Atrophy Plus Atrophy Of Optic Disc 3-Alpha Methylglutaconic Aciduria Type Iii Optic Atrophy 3 Optic Atrophy Infantile With Chorea And Spastic Paraplegia Autosomal Recessive Opa3 Autosomal Recessive Optic Atrophy 3 3-Methylglutaconic Aciduria 3 3-Alpha-Methylglutaconic Aciduria Type 3 Optic Atrophy 3 Autosomal Recessive Atrophy, Optic Atrophy, Optic, Plus Syndrome Optic Nerve Atrophy Primary Optic Atrophy Oa - [Optic Atrophy] Second Cranial Nerve Atrophy Second Cranium Nerve Atrophy
Tick Infestation	Tick Infestations
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Susceptibility To Lung Cancer, Protection Against Adenocarcinoma Of Lung, Somatic Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Mitochondrial Dna Depletion Syndrome	Mtdna Depletion Syndrome
Mitochondrial Myopathy	Mitochondrial Myopathies Mitochondrial Cytopathy Myopathies In Mitochondrial Disorders
Body Mass Index Quantitative Trait Locus 11	OBESITY Obesity, Susceptibility To Leanness, Inherited Obesity, Susceptibility To, Bmiq11 Obesity, Mild, Early-Onset Obesity, Association With Obesity, Early-Onset, Susceptibility To Obesity, Severe Obesity, Severe, And Type Ii Diabetes Obesity, Late-Onset Obesity , Susceptibility To BMIQ11 Obesity Bmiq11 Obesity, Early-Onset Simple Obesity Nos Excess Fat Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified Adiposis
Mitochondrial Encephalomyopathy	Mitochondrial Encephalomyopathies Encephalomyopathy, Mitochondrial
Diabetes Mellitus	Diabetes
Leigh Syndrome	Leigh Disease Infantile Subacute Necrotizing Encephalopathy Leigh Syndrome Due To Mitochondrial Complex Iv Deficiency LS Sne Leigh'S Disease Leigh Syndrome Due To Mitochondrial Complex I Deficiency Necrotizing Encephalopathy, Infantile Subacute, Of Leigh Subacute Necrotizing Encephalomyelopathy Necrotizing Encephalopathy Infantile Subacute Of Leigh Leigh Syndrome Due To Mitochondrial Complex Iii Deficiency Infantile Necrotizing Encephalomyelopathy Juvenile Subacute Necrotizing Encephalomyelopathy Leigh'S Necrotizing Encephalopathy Subacute Necrotizing Encephalopathy Juvenile Subacute Necrotizing Encephalopathy Leigh Syndrome Due To Mitochondrial Complex Ii Deficiency Leigh Syndrome Due To Mitochondrial Complex V Deficiency Encephalopathy, Subacute Necrotizing, Infantile Encephalopathy, Subacute Necrotizing, Juvenile Maternally Inherited Leigh Syndrome Subacute Necrotising Encephalomyelopathy Subacute Necrotising Encephalopathy
Leber Hereditary Optic Neuropathy, Modifier Of	Leber Optic Atrophy Leber Hereditary Optic Neuropathy LHON Leber'S Hereditary Optic Neuropathy Leber Optic Atrophy, Susceptibility To Leber'S Optic Atrophy LOAM Loas Leber'S Disease Leber'S Optic Neuropathy Optic Atrophy, Hereditary, Leber Lhon, Modifier Of Optic Atrophy, Leber Type Hereditary Optic Neuroretinopathy Leber Hereditary Optic Atrophy Loa Optic Atrophy Leber Type Leber Hereditary Optic Neuropathy, Modifier Leber Hereditary Optic Neuropathy Susceptibility Modifier Of Leber Hereditary Optic Neuropathy Lebers Hereditary Optic Neuropathy Leber Congenital Amaurosis
Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes	Melas Syndrome MELAS Mitochondrial Encephalomyopathy Lactic Acidosis And Stroke-Like Episodes Mitochondrial Myopathy, Lactic Acidosis, Stroke-Like Episode Mitochondrial Encephalomyopathy, Lactic Acidosis, And Stroke-Like Episodes Myopathy, Mitochondrial-Encephalopathy-Lactic Acidosis-Stroke Mitochondrial Encephalomyopathy, Lactic Acidosis And Stroke-Like Episodes Mitochondrial Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis And Stroke-Like Episodes Mitochondrial Encephalomyopathy With Lactic Acidosis And Stroke-Like Episodes Syndrome Myopathy, Mitochondrial, Encephalopathy, Lactic Acidosis, And Stroke-Like Episodes
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (12)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-50935	Troglitazone		99.78%	Unkown
HY-109015	Tucidinostat	Inhibitor	98.74%	Unkown
HY-B0165A	Pravastatin sodium		99.38%	Yes
HY-16276	Osilodrostat	Inhibitor	99.90%	Yes
HY-17005	Olmesartan medoxomil	Inhibitor	98.95%	Unkown
HY-B0023	Azelnidipine	Inhibitor	99.79%	Unkown
HY-100471	Esaxerenone	Antagonist	99.93%	Unkown
HY-16276A	Osilodrostat phosphate	Inhibitor	98.83%	Yes
HY-N7101	Cefpodoxime Proxetil	Inhibitor	98.93%	Unkown
HY-B1595	Cefmetazole	Inhibitor	98.82%	Unkown
HY-14818A	Laninamivir octanoate	Inhibitor	98.57%	Unkown
HY-B0165	Pravastatin		/	Unkown

Clinical Phase

Bioactive Molecules (17)

Art. -Nr.	Produktname	Wirkung	Reinheit	Phase
HY-160929	Linafexor	Agonist	99.58%	Phase 3
HY-124526	Chiauranib	Inhibitor	98.97%	Phase 3
HY-100401	Pactimibe	Inhibitor	99.98%	Phase 3
HY-16445	Sapacitabine	Chemical	98.69%	Phase 3
HY-141511	Coppersensor 1		≥98.0%	Phase 2
HY-14955	Managlinat dialanetil	Inhibitor	99.67%	Phase 2
HY-116228	Cadrofloxacin	Inhibitor	98.21%	Phase 2
HY-14783	Apricoxib	Inhibitor	98.84%	Phase 2
HY-106888A	CS-722		/	Phase 2
HY-123022	Tomopenem	Inhibitor	/	Phase 2
HY-137005	CS1		/	Phase 2
HY-14792	Inolitazone	Agonist	/	Phase 2
HY-P6306A	CS-6253 TFA		98.08%	Phase 1
HY-100413	CS-526	Antagonist	/	Phase 1
HY-145995	CS12192	Inhibitor	/	Phase 1
HY-14976	CS-0777	Modulator	/	Phase 1
HY-19404	Embeconazole	Inhibitor	/	Phase 1

Inhibitory Antibodies (2)

Art. -Nr.	Produktname	Wirkung	Reinheit	Phase
HY-P99758	Nofazinlimab	Inhibitor	98.83%	Phase 3
HY-P99270	Tigatuzumab	Inducer	98.18%	Phase 2

Pre-clinical Phase

Bioactive Molecules (84)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-B1692	L-Methionine-DL-sulfoximine	Inhibitor	≥98.0%	Unkown
HY-P6306	CS-6253		98.84%	Unkown
HY-148907	CS640	Inhibitor	99.48%	Unkown
HY-148913	CS587	Inhibitor	98.18%	Unkown
HY-P2727	Chondroitinase ABC		/	Unkown
HY-P3522	REDV		99.89%	Unkown
HY-B0165AR	Pravastatin sodium (Standard)		98.10%	Unkown
HY-W753658	Coppersensor-3		97.0%	Unkown
HY-124704	Chst15-IN-1	Inhibitor	98.01%	Unkown
HY-130086	Bis-PEG4-NHS ester		97.0%	Unkown
HY-121447	Heneicosanoic acid		98.0%	Unkown
HY-150611	EGFR-IN-70	Inhibitor	98.12%	Unkown
HY-14792B	Inolitazone dihydrochloride	Agonist	98.45%	Unkown
HY-43962	CS-1-65		99.54%	Unkown
HY-14180	PHA 408	Inhibitor	99.40%	Unkown
HY-100401A	Pactimibe sulfate	Inhibitor	98.0%	Unkown
HY-15801	HG-14-10-04	Inhibitor	98.53%	Unkown
HY-17005R	Olmesartan medoxomil (Standard)	Inhibitor	99.35%	Unkown
HY-50935S	Troglitazone-d4		98.19%	Unkown
HY-D0798	Catechol violet		90.0%	Unkown
HY-P10948A	CS-VIP 8 hydrochloride	Inhibitor	96.04%	Unkown
HY-105268	AzddMeC	Inhibitor	98.96%	Unkown
HY-106174	Lapisteride	Inhibitor	99.0%	Unkown
HY-106850	3′-Azido-2′,3′-dideoxyuridine	Inhibitor	99.59%	Unkown
HY-108493	CS-2100	Agonist	99.12%	Unkown
HY-109015S	Tucidinostat-d4	Inhibitor	98.63%	Unkown
HY-111640	3'-Azido-3'-deoxy-5-methylcytidine	Inhibitor	99.90%	Unkown
HY-P1816	Fibronectin CS1 Peptide		99.10%	Unkown
HY-P3522A	REDV TFA		99.81%	Unkown
HY-B0165CS	Pravastatin-d3 sodium salt		99.02%	Unkown
HY-Q51222	ZINC110492	Ligand	90.0%	Unkown
HY-100471S	Esaxerenone-d4	Antagonist	/	Unkown
HY-105114A	Imitrodast sodium	Inhibitor	/	Unkown
HY-106789	Plaunotol		/	Unkown
HY-106888	CS-722 Free base		/	Unkown
HY-128562	CS-1-69		/	Unkown
HY-133606	3,4,5-Trichlorosyringol		/	Unkown
HY-143445	EGFR-IN-48	Inhibitor	/	Unkown
HY-14792C	Inolitazone hydrochloride hydrate	Agonist	/	Unkown
HY-14818C	Laninamivir octanoate hydrate		/	Unkown
HY-148863	Cavα2δ1&NET-IN-2	Inhibitor	/	Unkown
HY-14977	CS-0777-P	Agonist	/	Unkown
HY-15115	SUAM 1221	Inhibitor	/	Unkown
HY-159936	CS4		/	Unkown
HY-163752	CS17919	Inhibitor	/	Unkown
HY-169247	Pam2CS-DMAPA		/	Unkown
HY-169427	FRF-06-057	Inhibitor	/	Unkown
HY-169982	EGFR-IN-136	Inhibitor	/	Unkown
HY-17005S	Olmesartan medoxomil-d6	Inhibitor	/	Unkown
HY-171958	PROTAC EGFR degrader 12	Degrader	/	Unkown
HY-173132	AKR1Cs-IN-1		/	Unkown
HY-175806	CS47		/	Unkown
HY-178242	PROTAC EGFR degrader 16	Degrader	/	Unkown
HY-179238	CS-1-103	Inhibitor	/	Unkown
HY-182626	CS1P1	Antagonist	/	Unkown
HY-186232	CS-1-102		/	Unkown
HY-186233	CS-1-174	Inhibitor	/	Unkown
HY-19633	CS-003 Free base	Antagonist	/	Unkown
HY-19633A	CS-003		/	Unkown
HY-B0023S	Azelnidipine-d7	Inhibitor	/	Unkown
HY-B0165AS	Pravastatin-13C,d3 sodium		/	Unkown
HY-B0165S	Pravastatin-d9 sodium		/	Unkown
HY-D3202	Lyso-CS2		/	Unkown
HY-N7101S	Cefpodoxime proxetil-d7		/	Unkown
HY-P10797	TAT-N24	Inhibitor	/	Unkown
HY-P10948	CS-VIP 8	Inhibitor	/	Unkown
HY-P4021	Mca-KKEDVV-Abu-CS-Abu-S-(NO2)F-KK-NH2		/	Unkown
HY-RS03221	CS Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W743398	Mexazolam		/	Unkown
HY-W783351	CS790AM		/	Unkown
HY-107163	CS 461	Inhibitor	/	Unkown
HY-116228A	Cadrofloxacin (hydrochloride)	Inhibitor	/	Unkown
HY-138024	Tacapenem	Inhibitor	/	Unkown
HY-14955A	(Rac)-Managlinat dialanetil		/	Unkown
HY-174532	Human TGFB3 mRNA		/	Unkown
HY-175198	Cs-2d	Inhibitor	/	Unkown
HY-175489	D-CS319	Inhibitor	/	Unkown
HY-178019	NDM-1-IN-10	Inhibitor	/	Unkown
HY-184611	Chitosan stabilized selenium nanoparticles		/	Unkown
HY-N7101S1	Cefpodoxime Proxetil-d6	Inhibitor	/	Unkown
HY-RS16750	Cs Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23189	Cs Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W667933	S-Propyl-L-cysteine sulfoxide		/	Unkown
HY-U00211	CS476	Inhibitor	/	Unkown

Inhibitory Antibodies (2)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-P992337	CS5001 Antibody	Inhibitor	/	Unkown
HY-P992511	CS2009	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	CS	VGNC	VGNC:27748
Felis catus	CS	VGNC	VGNC:61211
Canis familiaris	CS	VGNC	VGNC:49800
Mus musculus	CS	MGD	MGI:88529
Macaca mulatta	CS	VGNC	VGNC:71509
Rattus norvegicus	CS	RGD	RGD:620330
Others	CS	NCBI