FGFR
Fibroblast growth factor receptor
FGFR アイソフォーム特異的製品
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FGFR Inhibitors
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FGFR Agonists
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FGFR Antagonist
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FGFR Activators
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FGFR Modulators
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FGFR Control
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FGFR Ligands
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FGFR Proteins
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FGFR-1 Proteins
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FGFR-2 Proteins
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FGFR-3 Proteins
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FGFR-4 Proteins
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FGFR 関連製品 (395)
関連製品 (395)
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組換えタンパク質 (97)
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抗体 (11)
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FGFR Isoform Comparison
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Lenvatinib
0 Images別名: E7080; MK-7902 -
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Nintedanib
(ニンテダニブ)
0 Images別名: Nintedanib; BIBF 1120Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. -
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Regorafenib
0 Images別名: BAY 73-4506 -
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- Erdafitinib
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- Ponatinib
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Ferulic acid
0 ImagesFerulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively. -
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Lenvatinib mesylate
(Lenvatinib mesylate)
0 Images別名: E7080 mesylate -
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- Heparan Sulfate
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- Infigratinib
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- Formononetin (Formononetin)
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- PD173074 (PD173074)
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- Pazopanib
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- Pemigatinib
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Efruxifermin
0 Images別名: AKR-001; AMG-876Efruxifermin is an Fc-FGF21 fusion protein (human IgG1 Fc domain linked to a modified human FGF21). Efruxifermin has prolonged half-life and enhanced receptor affinity compared with native human FGF21. Efruxifermin can be used for the research of non-alcoholic steatohepatitis. -
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Futibatinib
0 Images別名: TAS-120Futibatinib (TAS-120) is an orally bioavailable, highly selective, and irreversible FGFR inhibitor, with IC50s of 3.9, 1.3, 1.6, and 8.3 nM for FGFR 1-4, respectively. Futibatinib inhibits mutant and wild-type FGFR2 with similar IC50s (wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM). -
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- SU 5402 (SU 5402)
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Nintedanib esylate
(Nintedanib esylate)
0 Images別名: BIBF 1120 (esylate); ニンテダニブエタンスルホン酸塩Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50s of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM, respectively. -
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- Fexagratinib
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bFGF (119-126)
0 ImagesbFGF (119-126) is a ligand of bFGF. The complex formed by bFGF (119-126) and bFGF can bind to FGFR1, while inhibiting the bFGF-FGFR1 interaction, FGFR1 phosphorylation and downstream signaling pathways. Therefore, bFGF (119-126) induces cell apoptosis and inhibits cell proliferation, migration, angiogenesis and metastasis. When conjugated with a carrier, bFGF (119-126) enhances cellular uptake via FGFR-mediated endocytosis and serves as an effective FGFR-targeted ligand. When used in combination with ultrasound and Doxorubicin (HY-15142A), bFGF (119-126) significantly enhances the inhibitory effect on tumors. bFGF (119-126) is applicable to research related to lung cancer, breast cancer, glioblastoma and ovarian cancer. -
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Triamcinolone acetonide
(トリアムシノロンアセトニド)
0 ImagesTriamcinolone acetonide inhibits basic fibroblast growth factor (bFGF) induced proliferation of retinal endothelial cells. Triamcinolone acetonide reduces chondrocyte viability and leads to cartilage destruction. Triamcinolone acetonide activates macrophage with anti-inflammatory characteristics. Triamcinolone acetonide can be used in the study of diseases such as atopic dermatitis. -
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Sorry. There is currently no product that acts on isoform Bcl-2, Bcl-W and Bim together.Please
try each isoform separately.