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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
nosocomial infections
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "nosocomial infections" in MCE Product Catalog:
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Research Areas:
Ceftolozane sulfate is a cephalosporin antibiotic active against Gram-negative pathogens. Ceftolozane sulfate acts as a bactericide and reduces Klebsiella pneumoniae thigh tissue loads in neutropenic mice. Ceftolozane sulfate can be used in studies related to bacterial infections .
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2 Cited Publications
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Ceftolozane TFA is a cephalosporin antibiotic active against Gram-negative pathogens. Ceftolozane TFA acts as a bactericide and reduces Klebsiella pneumoniae thigh tissue loads in neutropenic mice. Ceftolozane TFA can be used in studies related to bacterial infections .
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Cat. No.: HY-19806
CAS No.: 689293-68-3
Synonyms: CXA-101 free base; FR264205 free base
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Ceftolozane is a cephalosporin antibiotic active against Gram-negative pathogens. Ceftolozane acts as a bactericide and reduces Klebsiella pneumoniae thigh tissue loads in neutropenic mice. Ceftolozane can be used in studies related to bacterial infections .
Cat. No.: HY-106257S
Research Areas:
Ceftolozane-d6 TFA is the deuterated-labeled Ceftolozane TFA (HY-106257A). Ceftolozane TFA is a cephalosporin antibiotic active against Gram-negative pathogens. Ceftolozane TFA acts as a bactericide and reduces Klebsiella pneumoniae thigh tissue loads in neutropenic mice. Ceftolozane TFA can be used in studies related to bacterial infections .
Cat. No.: HY-108877
CAS No.: 107648-80-6
Synonyms: BMY-28142 hydrochloride
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Cefepime (BMY-28142) hydrochloride is a broad-spectrum, blood-brain barrier-permeable cephalosporin antibiotic with hPON1 inhibitory activity, with an IC50 of 21.115 mM and a Ki of 35.092 mM. Cefepime hydrochloride inhibits hPON1 via a non-competitive mechanism and blocks GABAA receptors. Cefepime hydrochloride penetrates the outer membrane of Gram-negative bacteria, inhibits the growth of Gram-positive and Gram-negative bacteria, and does not induce the production of β-lactamase .
Cat. No.: HY-106257AR
CAS No.: 1628046-32-1
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Ceftolozane TFA (Standard) is the analytical standard of Ceftolozane TFA (HY-106257A). This product is intended for research and analytical applications. Ceftolozane TFA is a cephalosporin antibiotic active against Gram-negative pathogens. Ceftolozane TFA acts as a bactericide and reduces Klebsiella pneumoniae thigh tissue loads in neutropenic mice. Ceftolozane TFA can be used in studies related to bacterial infections .
Cat. No.: HY-165465
CAS No.: 887774-94-9
Apo6619 is an iron chelator with antibacterial activity that inhibits a variety of common bacteria associated with hospital-acquired infections. Apo6619 inhibits the growth of relevant bacterial strains in cation-adjusted Mueller-Hinton broth and RPMI 1640 tissue culture medium. Apo6619 can be used in antibacterial research on hospital-acquired infection-related bacteria based on the iron chelation mechanism .
Cat. No.: HY-N19688
CAS No.: 74542-19-1
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Cat. No.: HY-N19688A
CAS No.: 316165-49-8
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Cat. No.: HY-128526
CAS No.: 160472-93-5
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Research Areas:
Acinetobactin is a bifunctional siderophore secreted by Acinetobacter baumannii that competitively binds ferric iron ions. Acinetobactin supplies A. baumannii by sequestering host-sequestered Fe 3+, while competitively depriving skin and respiratory commensal bacteria of iron resources, thereby exerting growth-inhibitory effects on Staphylococcus epidermidis, Staphylococcus hominis, Staphylococcus haemolyticus, and Corynebacterium striatum. The synthesis and transport of Acinetobactin enhance the intracellular epithelial colonization ability of A. baumannii, induce apoptosis of host epithelial cells, and simultaneously improve the survival and invasion capabilities of the bacterium in Galleria mellonella and mouse sepsis models. Acinetobactin can be used in A. baumannii-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
