Brassinin
Based on 2 publication(s) in Google Scholar
Brassinin is the metabolism of a phytoalexin from Beassica pekinensis (Lour. ) Rupr..
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.25%
- CAS. Nr.: 105748-59-2
- Formel: C11H12N2S2
- Molecular Weight:236.37
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Speicherung:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Brassinin
MoreAlle Endogenous Metabolite Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>100 μM
Compound: 1
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Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay
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[PMID: 24012378] |
| CCRF-CEM | IC50 |
90.2 μM
Compound: 1
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Antiproliferative activity against human CCRF-CEM cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity against human CCRF-CEM cells assessed as cell viability after 72 hrs by MTT assay
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[PMID: 24012378] |
| HeLa | IC50 |
>100 μM
Compound: 1
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Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay
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[PMID: 24012378] |
| Jurkat | IC50 |
>100 μM
Compound: 1
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Antiproliferative activity against human Jurkat cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity against human Jurkat cells assessed as cell viability after 72 hrs by MTT assay
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[PMID: 24012378] |
| K562 | IC50 |
128 μM
Compound: 3
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In vitro cytotoxic concentration measured against human myelogenous leukemia K562 cells
In vitro cytotoxic concentration measured against human myelogenous leukemia K562 cells
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[PMID: 15780632] |
| MCF7 | IC50 |
>100 μM
Compound: 1
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Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay
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[PMID: 24012378] |
| MDA-MB-231 | IC50 |
>100 μM
Compound: 1
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Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 72 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 72 hrs by MTT assay
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[PMID: 24012378] |
Chemical Information
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CAS. Nr. 105748-59-2
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Appearance Solid
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Molecular Weight 236.37
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Formel C11H12N2S2
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Color Off-white to light yellow
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SMILES
S=C(NCC1=CNC2=CC=CC=C21)SC
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Synonyms
Brassinine
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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ACS Environ Au
Machine Learning-Assisted Recognition of Environmental Sulfur-Containing Chemicals in Nontargeted Mass Spectrometry Analysis of Inadequate Mass Resolution. [Abstract]2025 Aug 5;5(6):573-582. PMID: 41277996 -
Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576
Lösungsmittel & Löslichkeit
DMSO : 50 mg/mL (211.53 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: 1.25 mg/mL (5.29 mM); Suspended solution; Need ultrasonic
This protocol yields a suspended solution of 1.25 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 1.25 mg/mL (5.29 mM); Suspended solution; Need ultrasonic
This protocol yields a suspended solution of 1.25 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (12.5 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Reinheit & Dokumentation
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Data Sheet (275 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2307 mL | 21.1533 mL | 42.3066 mL | 105.7664 mL |
| 5 mM | 0.8461 mL | 4.2307 mL | 8.4613 mL | 21.1533 mL | |
| 10 mM | 0.4231 mL | 2.1153 mL | 4.2307 mL | 10.5766 mL | |
| 15 mM | 0.2820 mL | 1.4102 mL | 2.8204 mL | 7.0511 mL | |
| 20 mM | 0.2115 mL | 1.0577 mL | 2.1153 mL | 5.2883 mL | |
| 25 mM | 0.1692 mL | 0.8461 mL | 1.6923 mL | 4.2307 mL | |
| 30 mM | 0.1410 mL | 0.7051 mL | 1.4102 mL | 3.5255 mL | |
| 40 mM | 0.1058 mL | 0.5288 mL | 1.0577 mL | 2.6442 mL | |
| 50 mM | 0.0846 mL | 0.4231 mL | 0.8461 mL | 2.1153 mL | |
| 60 mM | 0.0705 mL | 0.3526 mL | 0.7051 mL | 1.7628 mL | |
| 80 mM | 0.0529 mL | 0.2644 mL | 0.5288 mL | 1.3221 mL | |
| 100 mM | 0.0423 mL | 0.2115 mL | 0.4231 mL | 1.0577 mL |
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