NK 314
NK 314 is an inhibitor for topoisomerase IIα, which generates the break of DNA double-strand. NK 314 arrests the cell cycle at G2 phase in human acute myeloid leukemia cells, inhibits the proliferation of CEM with IC90 of 55 nM.
For research use only. We do not sell to patients.
- CAS No.: 208237-49-4
- Formula: C22H18ClNO4
- Molecular Weight:395.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Topoisomerase Isoforms
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Biological Activity
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topoisomerase II alpha |
Chemical Information
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CAS No. 208237-49-4
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Molecular Weight 395.84
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Formula C22H18ClNO4
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SMILES
OC1=C(C=CC2=C1C(CCC3)=[N+]3C4=C5C=C6OCOC6=CC5=CC=C24)OC.[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)