IL17A - interleukin 17A Gene

Sus scrofa

Also known as IL17

Gene ID: 449530 | Gene type: protein coding

About IL17A

Primary_assembly 7: 46,013,584-46,017,153 forward strand.Sscrofa11.1:CM000818.5

This gene has 1 transcript (splice variant), 97 orthologues and 5 paralogues. Low expression observed in reference dataset.

mRNA	Protein	Name
NM_001005729.1	NP_001005729.1	interleukin-17A precursor

IL17

Protein Preferred Names

Protein Names

interleukin-17A

IL-17	IL-17A
interleukin-17

Cat. No.	Product Name	Accession	Purity
HY-P700632	IL-17A Protein, Pig (N-His, C-Myc)	Q60I29 (G24-S153)	≥95%

Approval

Inhibitory Antibodies (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P9927	Secukinumab	Inhibitor	≥99.20%	Unkown
HY-P9924	Ixekizumab	Inhibitor	98.90%	Unkown
HY-P99280	Bimekizumab	Antagonist	95.00%	Unkown

Clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Phase
HY-103637A	Vimirogant hydrochloride	Inhibitor	98.39%	Phase 2
HY-103637	Vimirogant	Inhibitor	/	Phase 2
HY-107390A	AX-024 hydrochloride	Inhibitor	99.75%	Phase 1
HY-152851	Izumerogant	Agonist	/	Phase 1

Inhibitory Antibodies (5)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99515	Xeligekimab	Inhibitor	95.00%	Phase 3
HY-P99652	Gumokimab	Inhibitor	/	Phase 3
HY-P99563	Tibulizumab	Inhibitor	/	Phase 3
HY-P99397	Sonelokimab	Inhibitor	99.90%	Phase 2
HY-P99940	Remtolumab	Inhibitor	99.24%	Phase 2

Pre-clinical Phase

Bioactive Molecules (27)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15826	SGC-CBP30	Inhibitor	99.83%	Unkown
HY-139206	LY3509754	Inhibitor	99.65%	Unkown
HY-101913	IL-17A antagonist 1	Antagonist	99.74%	Unkown
HY-107390	AX-024	Inhibitor	99.29%	Yes
HY-145430	IL-17A modulator-1	Modulator	99.01%	Unkown
HY-139780	JNJ-61803534	Inhibitor	99.88%	Unkown
HY-145429	IL-17A modulator-2	Modulator	99.07%	Unkown
HY-101915	IL-17A antagonist 3	Antagonist	98.55%	Unkown
HY-119464	MRL-871	Agonist	98.18%	Unkown
HY-133552	RORγt Inverse agonist 10	Antagonist	99.13%	Unkown
HY-P3450	Erepdekinra	Antagonist	98.60%	Unkown
HY-128353	ROR agonist-1	Antagonist	/	Unkown
HY-126252	A-9758	Inhibitor	/	Unkown
HY-130243	RORγt Inverse agonist 6	Antagonist	98.97%	Unkown
HY-133128	FM26	Antagonist	/	Unkown
HY-139686	IL-17A inhibitor 2	Inhibitor	/	Unkown
HY-142939	RORγt modulator 4	Modulator	/	Unkown
HY-148272	IL-17A modulator-3	Modulator	/	Unkown
HY-153276	Androgen receptor-IN-5	Inhibitor	/	Unkown
HY-155243	12R-LOX-IN-1	Inhibitor	/	Unkown
HY-158159	IL17A-IN-1	Inhibitor	/	Unkown
HY-N0976	1,11b-Dihydro-11b-hydroxymedicarpin		/	Unkown
HY-N11768	4-Methoxylonchocarpin	Inhibitor	/	Unkown
HY-RS06695	IL17A Human Pre-designed siRNA Set A		/	Unkown
HY-RS06696	Il17a Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS06697	Il17a Rat Pre-designed siRNA Set A		/	Unkown
HY-155244	12R-LOX-IN-2	Inhibitor	99.85%	Unkown

Inhibitory Antibodies (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P9927A	Anti-Human IL-17A	Antagonist	96.32%	Unkown
HY-P99310	Perakizumab	Inhibitor	99.79%	Unkown
HY-P99335	Vunakizumab		95.00%	Unkown
HY-P99424	Afasevikumab	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	IL17A	NCBI	NCBI:3605
Canis familiaris	IL17A	NCBI	NCBI:481837
Macaca fascicularis	IL17A	NCBI	NCBI:102119976
Mus musculus	IL17A	NCBI	NCBI:16171
Susscrofa domestica	IL17A	NCBI
Leporidae	IL17A	NCBI
Rattus norvegicus	IL17A	NCBI	NCBI:301289
Macaca mulatta	IL17A	NCBI	NCBI:708123

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