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CDK9-IN-45

CDK9-IN-45 (Compound B11) is a highly selective CDK9 inhibitor with IC50 values for CDK9 and CDK1 of 7.13 and 489.5 nM respectively. CDK9-IN-45 exhibits a potent inhibitory effect on colorectal cancer cells. CDK9-IN-45 induces cell apoptosis and leads to significant accumulation of ROS. CDK9-IN-45 activates Caspase-3, downregulates Mcl-1, XIAP, and c-Myc. CDK9-IN-45 can be used for research on colorectal cancer.

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  • 分子式: C25H22FN5O3
  • 分子量:459.47
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • CDK9-IN-45 Chemical Structure
    CDK9-IN-45 構造式
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  • CDK9-IN-45 Chemical Structure
    CDK9-IN-45 Chemical Structure
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  • CDK9-IN-45