Cethromycin-d6
Based on 1 Customer Validation
Cethromycin-d6 (ABT-773-d6; Abbott-195773-d6; A-195773-d6) is the d6-labeled Cethromycin (HY-19655). Cethromycin (ABT-773; Abbott-195773) is an orally effective ketolide antibiotic with broad-spectrum antibacterial activity. Cethromycin binds to domains II/V of the 23S rRNA of the 50S subunit, inhibiting bacterial protein synthesis. Cethromycin can accumulate in lung tissue, alveolar macrophages, epithelial lining fluid, and human polymorphonuclear leukocytes. Cethromycin exhibits potent in vitro activity against a variety of respiratory pathogens, including Mycoplasma pneumoniae. Cethromycin exhibits significant intracellular and pulmonary enrichment and anti-inflammatory effects against mycoplasma pneumonia in mouse models, improving airway obstruction and airway hyperresponsiveness. Cethromycin disrupts the apicoplast and reduces liver-stage parasite burden during the liver stage of Plasmodium berghei. Cethromycin can be used in research related to pneumonia, Staphylococcus aureus infection, gonorrhea, and malaria.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 96.10%
- 分子式: C42H53D6N3O10
- 分子量:771.97
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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非標識Cas 205110-48-1
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性状 Solid
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分子量 771.97
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分子式 C42H53D6N3O10
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Color White to off-white
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SMILES
O[C@H]1[C@@](O[C@@H]([C@@](OC/C=C\C2=C([2H])C(C([2H])=C([2H])C([2H])=C3[2H])=C3N=C2[2H])(C)C[C@@H](C)C4=O)[C@@H](C)C([C@@H](C)C(O[C@H](CC)[C@](OC(N5)=O)(C)[C@@]5([H])[C@H]4C)=O)=O)([H])O[C@H](C)C[C@@H]1N(C)C
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別名
ABT-773-d6; Abbott-195773-d6; A-195773-d6
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
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データシート (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Keywords
- Cethromycin-d6
- ABT-773-d6
- Abbott-195773-d6
- A-195773-d6
- Isotope-Labeled Compounds
- Antibiotic
- Bacterial
- Parasite
- TNF Receptor
- IFNAR
- Interleukin Related
- Staphylococcus aureus
- Mycoplasma pneumoniae
- human polymorphonuclear leukocytes
- Streptococcus pneumoniae
- 50S ribosomal subunit
- Plasmodium berghei
- 23S rRNA domain II
- Mycobacterium avium complex
- Haemophilus influenzae
- Hepa1-6 cells
- Inhibitor
- inhibitor
- inhibit