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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
intra-abdominal infections
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "intra-abdominal infections" in MCE Product Catalog:
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Ceftolozane sulfate is a cephalosporin antibiotic active against Gram-negative pathogens. Ceftolozane sulfate acts as a bactericide and reduces Klebsiella pneumoniae thigh tissue loads in neutropenic mice. Ceftolozane sulfate can be used in studies related to bacterial infections .
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Sulopenem (CP-70429) is an orally active, parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. Sulopenem has the potential for urinary tract infections and intra-abdominal infections treatment. Sulopenem is inactive against Pseudomonas aeruginosa and Xanthomonas maltophilia .
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2 Cited Publications
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Ceftolozane TFA is a cephalosporin antibiotic active against Gram-negative pathogens. Ceftolozane TFA acts as a bactericide and reduces Klebsiella pneumoniae thigh tissue loads in neutropenic mice. Ceftolozane TFA can be used in studies related to bacterial infections .
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Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .
Cat. No.: HY-W561907
CAS No.: 85960-17-4
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IMipenem and cilastatin sodium is a broad-spectrum Carbapenem Antibiotic combination. Imipenem (HY-B1369A) is a Carbapenem antibiotic. IMipenem demonstrates excellent activity against gram-positive and gram-negative aerobic and anaerobic organisms. Cilastatin (HY-A0166) is a renal Dehydropeptidase inhibitor that inhibits the metabolism of Imipenem by renal brush-border enzymes, thus increasing imipenem concentrations in urine .
Cat. No.: HY-B1257
CAS No.: 56796-39-5
Synonyms: Sodium cefmetazole
Target:
Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
Cat. No.: HY-19806
CAS No.: 689293-68-3
Synonyms: CXA-101 free base; FR264205 free base
Target:
Research Areas:
Ceftolozane is a cephalosporin antibiotic active against Gram-negative pathogens. Ceftolozane acts as a bactericide and reduces Klebsiella pneumoniae thigh tissue loads in neutropenic mice. Ceftolozane can be used in studies related to bacterial infections .
Cat. No.: HY-B1595
CAS No.: 56796-20-4
Synonyms: CS 1170
Target:
Cefmetazole (CS 1170) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative and anaerobic bacteria. Cefmetazole binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
Cat. No.: HY-106257S
Research Areas:
Ceftolozane-d6 TFA is the deuterated-labeled Ceftolozane TFA (HY-106257A). Ceftolozane TFA is a cephalosporin antibiotic active against Gram-negative pathogens. Ceftolozane TFA acts as a bactericide and reduces Klebsiella pneumoniae thigh tissue loads in neutropenic mice. Ceftolozane TFA can be used in studies related to bacterial infections .
Cat. No.: HY-139554
CAS No.: 1420294-56-9
Synonyms: KBP-7072
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Research Areas:
Zifanocycline (KBP-7072) is a semisynthetic third-generation aminomethylcycline antibiotic that inhibits the normal function of the bacterial ribosome. Zifanocycline exhibits a broad spectrum of in vitro antibacterial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline is available in both oral and injectable formulations. Zifanocycline can be used for the research of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections .
Cat. No.: HY-139805
CAS No.: 34787-01-4
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Ticarcillin is a semisynthetic, extended-spectrum, carboxypenicillin antibacterial agent, and is active against gram-positive cocci, including streptococci and staphylococci. Ticarcillin is also effective against most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin can be used in lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections research .
Cat. No.: HY-105284A
CAS No.: 112294-81-2
Synonyms: CP-70429 sodium
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Research Areas:
Sulopenem (sodium)(CP-70429 (sodium)) is an orally active, parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. Sulopenem has the potential for urinary tract infections and intra-abdominal infections treatment. Sulopenem is inactive against Pseudomonas aeruginosa and Xanthomonas maltophilia .
Cat. No.: HY-139554AR
Synonyms: KBP-7072 TFA (Standard)
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Zifanocycline (TFA) (Standard) is the analytical standard of Zifanocycline (TFA). This product is intended for research and analytical applications. Zifanocycline (KBP-7072) TFA is an orally active, semi-synthetic aminomethylcycline antibiotic that inhibits the normal function of bacterial ribosomes. Zifanocycline TFA has broad spectrum in vitro antimicrobial activity against Gram-positive and Gram-negative bacteria, including many multidrug-resistant pathogens. Zifanocycline TFA is indicated for the study of acute bacterial skin and skin structure infections, community-acquired bacterial pneumonia, and complicated intra-abdominal infections[1][2].
Cat. No.: HY-139805A
CAS No.: 74682-62-5
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Ticarcillin monosodium is a semisynthetic, extended-spectrum, carboxypenicillin antibacterial agent, and is active against gram-positive cocci, including streptococci and staphylococci. Ticarcillin monosodium is also effective against most gram-negative organisms, including Pseudomonas aeruginosa. Ticarcillin monosodium can be used in lower respiratory tract infections, skin and skin structure infections, urinary tract infections, and intraabdominal infections research .
Cat. No.: HY-B1257R
CAS No.: 56796-39-5
Synonyms: Sodium cefmetazole (Standard)
Target:
Cefmetazole (sodium) (Standard) is the analytical standard of Cefmetazole (sodium). This product is intended for research and analytical applications. Cefmetazole sodium (Sodium cefmetazole) is a semisynthetic cephamycin antibiotic with broad-spectrum antibacterial activity, covering gram-positive, gram-negative, and anaerobic bacteria. Cefmetazole sodium binds to penicillin binding proteins (PBPs), resulting in interfering bacterial cell wall biosynthesis. Cefmetazole sodium is used for the research of gynecologic, intraabdominal, urinary tract, respiratory tract and skin and soft tissue infections .
Cat. No.: HY-W923278
CAS No.: 73547-70-3
Synonyms: GR20263 dihydrochloride
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Ceftazidime (GR20263) dihydrochloride is a cephalosporin β-lactam antibiotic. Ceftazidime dihydrochloride exhibits activity against susceptible Enterobacteriaceae, multidrug-resistant Gram-negative bacteria, Pseudomonas aeruginosa, and bacteria producing Ambler class A, C, and some class D β-lactamases, but shows no activity against microorganisms producing metallo-β-lactamases. Ceftazidime dihydrochloride reduces bacterial loads in mouse models of splenic, hepatic, and thigh infections, but has low efficacy against ESBL- and KPC-producing Enterobacteriaceae. Ceftazidime dihydrochloride can be used in research related to complicated urinary tract infections, complicated intra-abdominal infections, hospital-acquired pneumonia, carbapenemase-producing Klebsiella pneumoniae infections, carbapenem-resistant Enterobacterales infections, and severe Gram-negative bacterial infections .
Cat. No.: HY-106257AR
CAS No.: 1628046-32-1
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Ceftolozane TFA (Standard) is the analytical standard of Ceftolozane TFA (HY-106257A). This product is intended for research and analytical applications. Ceftolozane TFA is a cephalosporin antibiotic active against Gram-negative pathogens. Ceftolozane TFA acts as a bactericide and reduces Klebsiella pneumoniae thigh tissue loads in neutropenic mice. Ceftolozane TFA can be used in studies related to bacterial infections .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
