TU-100
TU-100 is a Japanese herbal medicine. TU-100 exhibits anti-cancer effects by regulating cancer-associated fibroblasts (CAFs) in the TME. TU-100 can antagonize the M2 polarization phenotype of macrophages in the tumor microenvironment by suppressing the TLR4/NF-κB/STAT3 axis. TU-100 can inhibit the high expression of MMP-2, COX-2, and VEGF in TAMs.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1310907-71-1
- Fòrmula: C20H13NO3
- Peso molecular:315.32
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
|
TLR4 |
STAT3 |
MMP-2 |
COX-2 |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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No. CAS 1310907-71-1
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Peso molecular 315.32
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Fòrmula C20H13NO3
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SMILES
O=C1C2=C(C(C3=C1C4C(C5=C(C3N4C)C=CC=C5)=O)=O)C=CC=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TU-100 Related Classifications
HY-165386 Related Classifications
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