Cat. No.: HY-N7627

Regaloside C

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Based on 1 Customer Validation

Regaloside C is an anti-inflammatory agent and antioxidant that scavenges ABTS and DPPH free radicals. Regaloside C targets multiple molecules including TNF-α, MMP-2, ERα, AKT1, TLR4 and HSP90-α. Regaloside C is applicable to research related to inflammatory diseases.

For research use only. We do not sell to patients.

Purity: 99.62%
CAS No.: 117591-85-2
Formula: C₁₈H₂₄O₁₁
Molecular Weight:416.38

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Regaloside C Chemical Structure

CAS No.: 117591-85-2

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Sample (0.1mg)

In-stock

(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
- In Vivo
Purity & Documentation
References
Help & FAQs
Bioz

Biological Activity

Description

IC₅₀ & Target

TLR4

MMP-2

HSP90α

Akt1

Estrogen receptor

All Estrogen Receptor/ERR Isoforms :

All Toll-like Receptor (TLR) Isoforms :

All Akt Isoforms :

All MMP Isoforms :

All HSP Isoforms :

In Vitro

Regaloside C (6.25-400 μM; 7 min) potently scavenges ABTS cationic radicals with an IC₅₀ of 139.0 μM in a cell-free assay^[2].
Regaloside C (6.25-400 μM; 30 min) potently scavenges DPPH anionic radicals with an IC₅₀ of 51.6 μM in a cell-free assay^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 117591-85-2
Appearance Solid
Molecular Weight 416.38
Formula C₁₈H₂₄O₁₁
Color Off-white to yellow
SMILES

O[C@H](COC(/C=C/C(C=C1)=CC(O)=C1O)=O)CO[C@@H]([C@@H]([C@H]2O)O)O[C@@H]([C@H]2O)CO
Structure Classification
- Phenylpropanoids
- Simple Phenylpropanols
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (240.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.4017 mL

12.0083 mL

24.0165 mL

5 mM

0.4803 mL

2.4017 mL

4.8033 mL

10 mM

0.2402 mL

1.2008 mL

2.4017 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

Stock Solution Working Solution

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline

Solubility: ≥ 2.5 mg/mL (6.00 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)

Solubility: ≥ 2.5 mg/mL (6.00 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg
Animal Weight (Per Animal) Animal Weight (Per Animal)
g
Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL
Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

%
DMSO +

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
%
+
+
%
Tween-80 + +
%
Saline +

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Working solution concentration: 0.22 mg/mL

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Portuguese - PT (392 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hu M, Zhang S, Luo F, et al. Potential mechanisms underlying the protective effects of lily bulbs extract and characteristic ingredients against LPS-induced inflammation in HaCaT cells[J]. Food Bioscience, 2025, 66: 106142.

[2]. Seo C S, Kim N S, Song K H. The HPLC–PDA Method for Simultaneous Determination of Regalosides from Bulbs of Lilium lancifolium Thunb. and Their Antioxidant Effects[J]. Plants, 2024, 13(19): 2793.

[3]. Chen G, et al. Total Glycosides and Regaloside B from Lily: Potential Therapeutic Agents for Osteogenic Differentiation, Migration, and Angiogenesis. ACS Omega. 2025;10(29):31638-31648. Published 2025 Jul 20. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.4017 mL	12.0083 mL	24.0165 mL	60.0413 mL
	5 mM	0.4803 mL	2.4017 mL	4.8033 mL	12.0083 mL
	10 mM	0.2402 mL	1.2008 mL	2.4017 mL	6.0041 mL
	15 mM	0.1601 mL	0.8006 mL	1.6011 mL	4.0028 mL
	20 mM	0.1201 mL	0.6004 mL	1.2008 mL	3.0021 mL
	25 mM	0.0961 mL	0.4803 mL	0.9607 mL	2.4017 mL
	30 mM	0.0801 mL	0.4003 mL	0.8006 mL	2.0014 mL
	40 mM	0.0600 mL	0.3002 mL	0.6004 mL	1.5010 mL
	50 mM	0.0480 mL	0.2402 mL	0.4803 mL	1.2008 mL
	60 mM	0.0400 mL	0.2001 mL	0.4003 mL	1.0007 mL
	80 mM	0.0300 mL	0.1501 mL	0.3002 mL	0.7505 mL
	100 mM	0.0240 mL	0.1201 mL	0.2402 mL	0.6004 mL

Keywords

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Regaloside C

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All Estrogen Receptor/ERR Isoforms

All Toll-like Receptor (TLR) Isoforms

All Akt Isoforms

All MMP Isoforms

All HSP Isoforms

Biological Activity

Chemical Information