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aspergillus fumigatus infection

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By Targets:	Antibiotic (3) Apoptosis (1) Bacterial (2) Cytochrome P450 (1) Endogenous Metabolite (1) Fungal (9) HIV (2) Isotope-Labeled Compounds (1) Parasite (2) Reference Standards (1) Topoisomerase (1)
By Research Areas:	Cancer (1) Infection (13) Inflammation/Immunology (1)

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Natural
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Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0751

Fumagillin Amebacilin; NSC9168	Parasite HIV Antibiotic	Infection
Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.

HY-N2198

Podocarpusflavone A	Fungal Bacterial Topoisomerase Apoptosis	Infection Inflammation/Immunology Cancer
Podocarpusflavone A is a biflavonoid present in the leaves of Podocarpus henkelii, with anti-tumor, topoisomerase I inhibitory, antibacterial and antifungal activities. Podocarpusflavone A exhibits antibacterial activity against Enterococcus faecalis and Pseudomonas aeruginosa. Podocarpusflavone A shows weak activity against fungal pathogens. Podocarpusflavone A targets topoisomerase I and induces cell cycle arrest and apoptosis in MCF-7 cells. Podocarpusflavone A can be used for studies on cancer, bacterial and fungal infections .

HY-B0751R

Fumagillin (Standard) Amebacilin (Standard); NSC9168 (Standard)	Reference Standards Parasite HIV Antibiotic	Infection
Fumagillin (Standard) is the analytical standard of Fumagillin. This product is intended for research and analytical applications. Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.

HY-108079

KOS-2079	Fungal	Infection
KOS-2079 is an antifungal agent. KOS-2079 has strong inhibitory activity against Aspergillus flavus 204303 (MIC = 1.10 μg/mL) and Aspergillus fumigatus 204305 (MIC = 1.32 μg/mL). KOS-2079 is commonly used in the study of fungal infection .

HY-N14018

Glidobactin A	Antibiotic Fungal	Infection
Glidobactin A is an acyl peptide antibiotic. Glidobactin A has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice .

HY-N19644

(-)-Oxysporidinone	Fungal	Infection
(-)-Oxysporidinone is an antifungal agent. (-)-Oxysporidinone inhibits the growth of Aspergillus fumigatus and Cryptococcus neoformans. (-)-Oxysporidinone can be used in studies related to fungal infections .

HY-N12106

Neosartoricin Fumicycline	Endogenous Metabolite Fungal	Infection
Neosartoricin (Fumicycline) (Compound 3), a prenylated anthracenone, is a microbial secondary metabolite. Neosartoricin can be isolated from Aspergillus fumigatus and Neosartorya fischeri. Neosartoricin has immunosuppressive activity, and significantly inhibits T-cell proliferative activity with an IC₅₀ of 3 μM. Neosartoricin may be beneficial to fungal defense, facilitating infection through suppressing the host adaptive immunity without involvement of primary virulence .

HY-N19755

Clemontanoside-C	Fungal	Infection
Clemontanoside-C is an oleanane-based triterpenoid saponin and antifungal agent found in the roots of Lepidagathis cuspidata. Clemontanoside-C acts against Aspergillus flavus, Rhizopus stolinifer, Penicillum nodatum, and Aspergillus fumigatus. Clemontanoside-C can be used for the research of fungal infections .

HY-N9869

(E,Z)-Platanoside	Bacterial	Infection
(E,Z)-Platanoside is a flavonoid glycoside. (E,Z)-Platanoside is a potent and highly selective MRSA inhibitor; it exhibits low activity against other tested strains, including Gram-negative bacteria, intracellular Mycobacterium intracellulare, Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus. (E,Z)-Platanoside can be used in research on MRSA infections .

HY-W069116

Antifungal agent 146	Fungal	Infection
Antifungal agent 146 (Compound 19l) is a broad-spectrum antifungal agent. Antifungal agent 146 has inhibitory effects on the main dermatophytes that cause onychomycosis (Trichophyton rubrum, Trichophyton mentagrophytes) and other fungi (Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus) with MIC values of 16, 16, 64, 32, and 32 μg/mL. Antifungal agent 146 can be used for the research of infection .

HY-B0751S

Fumagillin-13C26 Amebacilin-¹³C₂₆; NSC9168-¹³C₂₆	Isotope-Labeled Compounds	Infection
Fumagillin- ¹³C₂₆ (Amebacilin- ¹³C₂₆) is the ¹³C-labeled Fumagillin (HY-B0751). Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.

HY-183333

CHNQD-02204	Fungal	Infection
CHNQD-02204 is a potent and selective antifungal agent with in vitro activity against Candida albicans, with a MIC of 0.025 μg/mL. CHNQD-02204 inhibits ergosterol biosynthesis, disrupts the membrane integrity and biofilm formation of Candida albicans, and suppresses the morphological transition of Candida albicans from yeast to hyphal form. CHNQD-02204 can be used in studies related to candidal infections .

HY-136760

CYP51-IN-10	Cytochrome P450 Fungal	Infection
CYP51-IN-10 is cytochrome P450 14a-demethylase (CYP51) inhibitor with antifungal activity. CYP51-IN-10 can be used for the research of fungal infection .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0751

Fumagillin Amebacilin; NSC9168	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Parasite HIV Antibiotic
Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.

HY-N2198

Podocarpusflavone A	Structural Classification Flavonoids Classification of Application Fields Guttiferae Phenols Polyphenols Plants Garcinia subelliptica Biflavones Disease Research Fields Source Classification Cancer	Fungal Bacterial Topoisomerase Apoptosis
Podocarpusflavone A is a biflavonoid present in the leaves of Podocarpus henkelii, with anti-tumor, topoisomerase I inhibitory, antibacterial and antifungal activities. Podocarpusflavone A exhibits antibacterial activity against Enterococcus faecalis and Pseudomonas aeruginosa. Podocarpusflavone A shows weak activity against fungal pathogens. Podocarpusflavone A targets topoisomerase I and induces cell cycle arrest and apoptosis in MCF-7 cells. Podocarpusflavone A can be used for studies on cancer, bacterial and fungal infections .

HY-B0751R

Fumagillin (Standard) Amebacilin (Standard); NSC9168 (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source Classification	Reference Standards Parasite HIV Antibiotic
Fumagillin (Standard) is the analytical standard of Fumagillin. This product is intended for research and analytical applications. Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.

HY-N14018

Glidobactin A	Microorganisms Antibiotics Other Antibiotics Source Classification	Antibiotic Fungal
Glidobactin A is an acyl peptide antibiotic. Glidobactin A has activity against Candida, Aspergillus fumigatus and Trichophyton, but it is not effective against Candida albicans M-9 infection in mice .

HY-N19644

(-)-Oxysporidinone	Structural Classification Alkaloids Microorganisms Other Alkaloids Source Classification	Fungal
(-)-Oxysporidinone is an antifungal agent. (-)-Oxysporidinone inhibits the growth of Aspergillus fumigatus and Cryptococcus neoformans. (-)-Oxysporidinone can be used in studies related to fungal infections .

HY-N12106

Neosartoricin Fumicycline	Microorganisms Phenols Polyphenols Source Classification	Endogenous Metabolite Fungal
Neosartoricin (Fumicycline) (Compound 3), a prenylated anthracenone, is a microbial secondary metabolite. Neosartoricin can be isolated from Aspergillus fumigatus and Neosartorya fischeri. Neosartoricin has immunosuppressive activity, and significantly inhibits T-cell proliferative activity with an IC₅₀ of 3 μM. Neosartoricin may be beneficial to fungal defense, facilitating infection through suppressing the host adaptive immunity without involvement of primary virulence .

HY-N19755

Clemontanoside-C	Triterpenes Structural Classification Acanthaceae Terpenoids Plants Lepidagathis cuspidata Nees Source Classification	Fungal
Clemontanoside-C is an oleanane-based triterpenoid saponin and antifungal agent found in the roots of Lepidagathis cuspidata. Clemontanoside-C acts against Aspergillus flavus, Rhizopus stolinifer, Penicillum nodatum, and Aspergillus fumigatus. Clemontanoside-C can be used for the research of fungal infections .

HY-N9869

(E,Z)-Platanoside	Structural Classification Platanus occidentalis L. Phenols Polyphenols Platanaceae Plants Saccharides Monosaccharides Source Classification	Bacterial
(E,Z)-Platanoside is a flavonoid glycoside. (E,Z)-Platanoside is a potent and highly selective MRSA inhibitor; it exhibits low activity against other tested strains, including Gram-negative bacteria, intracellular Mycobacterium intracellulare, Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus. (E,Z)-Platanoside can be used in research on MRSA infections .

Cat. No.	Product Name	Chemical Structure

HY-B0751S

Fumagillin-13C26
Fumagillin- ¹³C₂₆ (Amebacilin- ¹³C₂₆) is the ¹³C-labeled Fumagillin (HY-B0751). Fumagillin(NSC9168) is an antimicrobial compound first isolated in 1949 from the fungus Aspergillus fumigatu. Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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aspergillus fumigatus infection

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products