TU-100
TU-100 is a Japanese herbal medicine. TU-100 exhibits anti-cancer effects by regulating cancer-associated fibroblasts (CAFs) in the TME. TU-100 can antagonize the M2 polarization phenotype of macrophages in the tumor microenvironment by suppressing the TLR4/NF-κB/STAT3 axis. TU-100 can inhibit the high expression of MMP-2, COX-2, and VEGF in TAMs.
For research use only. We do not sell to patients.
- CAS No.: 1310907-71-1
- Formula: C20H13NO3
- Molecular Weight:315.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
|
TLR4 |
STAT3 |
MMP-2 |
COX-2 |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1310907-71-1
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Molecular Weight 315.32
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Formula C20H13NO3
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SMILES
O=C1C2=C(C(C3=C1C4C(C5=C(C3N4C)C=CC=C5)=O)=O)C=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TU-100 Related Classifications
HY-165386 Related Classifications
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