Pomalidomide-d4
Based on 1 Customer Validation
Pomalidomide-d4 (CC-4047-d4) is the deuterated-labeled Pomalidomide (HY-10984). Pomalidomide (CC-4047) is an immunomodulatory agent. Pomalidomide downregulates TNF-alpha, IL-1, IL-11, and IL-12, upregulates IL-2, IL-5, and IL-10, and costimulates T cells. Pomalidomide inhibits the proliferation of T regulatory cells by reducing FOXP3/OX-40 expression and IL-2-mediated expansion. Pomalidomide inhibits CDK2/4/6 and p21WAF-1, causing cell cycle arrest. Pomalidomide can be used in research on myelofibrosis-associated anemia, multiple myeloma, and colorectal cancer.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 96.38%
- CAS No.: 1416575-78-4
- Formule: C13H7D4N3O4
- Masse moléculaire:277.27
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform TNF Receptor
MoreVoir tous les produits spécifiques à Isoform Orexin Receptor (OX Receptor)
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Activité biologique
Description
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IL-1 |
TNF-alpha |
IL-12 |
IL-2 |
IL-5 |
IL-10 |
IL-11 |
FOXP3 |
CDK2 |
OX-40 |
CDK4 |
CDK6 |
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1416575-78-4
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Unlabeled CAS 19171-19-8
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Appearance Solid
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Masse moléculaire 277.27
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Formule C13H7D4N3O4
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Color White to yellow
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SMILES
O=C1N(C2C(NC(C([2H])([2H])C2([2H])[2H])=O)=O)C(C3=C(N)C=CC=C31)=O
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Synonyms
CC-4047-d4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureté et documentation
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Fiche technique (279 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pomalidomide-d4 Related Classifications
HY-10984S2 Related Classifications
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Keywords
- Pomalidomide-d4
- 1416575-78-4
- CC-4047-d4
- Isotope-Labeled Compounds
- TNF Receptor
- Interleukin Related
- FOXP
- Orexin Receptor (OX Receptor)
- CDK
- Tumor Necrosis Factor Receptor
- TNFR
- IL
- Forkhead Box P Protein
- Hypocretin Receptor
- HCRT Receptor
- Cyclin dependent kinase
- FOXP3
- IL-1
- IL-10
- IL-11
- IL-12
- IL-2
- IL-5
- T cells
- T-regulatory cell
- TNF-alpha
- Inhibitor
- inhibitor
- inhibit