INH2BP
INH2BP is a poly(ADP-ribose) polymerase (PARP) inhibitor with antioxidant and anti-apoptotic activities. INH2BP reduces the production of intracellular reactive oxygen species (ROS), modulates the expression of apoptosis-related proteins such as Bax, Bcl-2 and cleaved caspase-3 and enhances cell survival through the activation of the ERK1/2 and p38 MAPK signaling pathways. INH2BP is promising for research of cardiovascular diseases.
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- CAS. Nr.: 137881-27-7
- Formel: C9H6INO2
- Molecular Weight:287.05
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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p38 MAPK |
ERK1 |
ERK2 |
Caspase-3 |
Chemical Information
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CAS. Nr. 137881-27-7
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Molecular Weight 287.05
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Formel C9H6INO2
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SMILES
O=C1C=CC2=C(I)C(N)=CC=C2O1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)