Liriodendrin
Based on 1 publication(s) in Google Scholar
Liriodendrin is an HSF1 agonist can be isolated from E. ulmoides.
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- 純度: 99.02%
- CAS 番号: 573-44-4
- 分子式: C34H46O18
- 分子量:742.72
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保管条件:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
MedChemExpress(MCE)の使用を引用している文献 Liriodendrin
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生物活性
HSF1[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
>100 μM
Compound: 21
|
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction based assay
Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced NO production after 24 hrs in presence of LPS by Griess reaction based assay
|
[PMID: 28911817] |
| Cancer cell lines | ED50 |
16 μg/mL
Compound: 6
|
Cytotoxicity against human colon cancer cells
Cytotoxicity against human colon cancer cells
|
[PMID: 1965200] |
| Cancer cell lines | ED50 |
30 μg/mL
Compound: 6
|
Cytotoxicity against human breast cancer cells
Cytotoxicity against human breast cancer cells
|
[PMID: 1965200] |
| Cancer cell lines | ED50 |
6 μg/mL
Compound: 6
|
Cytotoxicity against human lung cancer cells
Cytotoxicity against human lung cancer cells
|
[PMID: 1965200] |
| HT-1080 | ED50 |
8.9 μg/mL
Compound: 6
|
Cytotoxicity against human HT1080 cells
Cytotoxicity against human HT1080 cells
|
[PMID: 1965200] |
| KB | ED50 |
6 μg/mL
Compound: 6
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 1965200] |
| Melanoma cell | ED50 |
19 μg/mL
Compound: 6
|
Cytotoxicity against human melanoma cells
Cytotoxicity against human melanoma cells
|
[PMID: 1965200] |
| N9 | IC50 |
>100 μM
Compound: 19
|
Antineuroinflammatory activity in mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Antineuroinflammatory activity in mouse N9 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
|
[PMID: 28073678] |
| P388 | ED50 |
2.4 μg/mL
Compound: 6
|
Cytotoxicity against mouse P388 cells
Cytotoxicity against mouse P388 cells
|
[PMID: 1965200] |
| RAW264.7 | IC50 |
0.112 mM
Compound: 24
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs
|
[PMID: 18986199] |
| RAW264.7 | IC50 |
0.112 μM/mL
Compound: 24
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs
|
[PMID: 18986199] |
化学情報
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CAS 番号 573-44-4
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性状 Solid
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分子量 742.72
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分子式 C34H46O18
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Color White to off-white
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SMILES
COC1=C(O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)C(OC)=CC([C@@H]3[C@]4([H])[C@@](CO3)([H])[C@@H](C5=CC(OC)=C(C(OC)=C5)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO)OC4)=C1
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Int J Mol Med
Liriodendrin alleviates myocardial ischemia‑reperfusion injury via partially attenuating apoptosis, inflammation and mitochondria damage in rats. [Abstract]2025 Apr;55(4):65. PMID: 39981888
純度とドキュメンテーション
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データシート (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)