349 Results for "

fungal infection

" in MedChemExpress (MCE) Product Catalog:
Products (349)

349 Results for "fungal infection" in MCE Product Catalog:

44
44 Publications Verification
Cat. No.: HY-N0150
CAS No.: 22373-78-0
Synonyms: Monensin A sodium
Monensin (Monensin A) sodium, an orally active antibiotic, is an ionophore that mediates Na +/H + exchange. Monensin sodium is a potent Wnt signaling inhibitor. Monensin sodium causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin sodium can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects .
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44
44 Publications Verification
Cat. No.: HY-N4302
CAS No.: 17090-79-8
Synonyms: Monensin A
Monensin (Monensin A), an orally active antibiotic, is an ionophore that mediates Na +/H + exchange. Monensin is a potent Wnt signaling inhibitor. Monensin causes a marked enlargement of the multivesicular bodies (MVBs) and regulates exosome secretion. Monensin can be used for bacterial, fungal, and parasitic infections research, and shows anticancer effects .
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19
19 Cited Publications
Cat. No.: HY-17395
CAS No.: 78628-80-5
Synonyms: TDT 067 hydrochloride
Research Areas:  

Infection

Terbinafine hydrochloride (TDT 067 hydrochloride) is an orally active and potent antifungal agent. Terbinafine hydrochloride is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine hydrochloride also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria . Terbinafine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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19
19 Cited Publications
Cat. No.: HY-17395A
CAS No.: 91161-71-6
Synonyms: TDT 067
Research Areas:  

Infection

Terbinafine (TDT 067) is an orally active and potent antifungal agent. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria . Terbinafine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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12
12 Cited Publications
Cat. No.: HY-N6798
CAS No.: 35891-70-4
Synonyms: Thermozymocidin; ISP-I
Myriocin (Thermozymocidin), a fungal metabolite could be isolated from Myriococcum albomyces, Isaria sinclairi and Mycelia sterilia, is a potent inhibitor of serine-palmitoyl-transferase (SPT) and a key enzyme in de novo synthesis of sphingolipids. Myriocin suppresses replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL for inhibiting HCV infection .
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3
3 Cited Publications
Cat. No.: HY-N1073
CAS No.: 51225-30-0
Synonyms: 6-Isopentenylgenistein; Erythrinin B
Wighteone (6-Isopentenylgenistein; Erythrinin B) is a prenylated isoflavone that acts as a HSP90/EGFR L858R/T790M inhibitor and antifungal agent. Wighteone reduces the expression level of HSP90, blocks EGF-induced phosphorylation of EGFR, and thereby inhibits the downstream ERK and AKT signaling pathways. Wighteone induces cell cycle redistribution, inhibits proliferation and triggers apoptosis in cancer cells. Wighteone can be isolated from Erythrina suberosa, and can also be induced to synthesize in Lotus japonicus under specific conditions. Wighteone can be used to study HER2-positive breast cancer, leukemia, non-small cell lung cancer with EGFR L858R/T790M mutation, and fungal infections .
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3
3 Cited Publications
Cat. No.: HY-100373
CAS No.: 946075-13-4
Purity:  95.97%
Synonyms: BAL8557-002
Target:  

Fungal

Research Areas:  

Infection

Isavuconazonium sulfate (BAL8557-002) is an orally active broad-spectrum antifungal molecule. Isavuconazonium sulfate is a precursor of the triazole antifungal active molecule Isavuconazole. Isavuconazonium sulfate can be used in the study of invasive aspergillosis, mucormycosis, blastomycosis, and Acanthamoeba keratitis .
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2
2 Cited Publications
Cat. No.: HY-N6647
CAS No.: 20633-84-5
Luteolin-7-rutinoside has both anti-arthritic and antifungal activities, can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
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2
2 Cited Publications
Cat. No.: HY-N1970
CAS No.: 31721-94-5
5,7-Dihydroxychromone is a flavonoid compound with antioxidant properties. 5,7-Dihydroxychromone induces Nrf2 nuclear translocation, increases Nrf2/ARE binding activity, and up-regulates Nrf2-dependent antioxidant genes HO-1, NQO1, GCLc. 5,7-Dihydroxychromone attenuates excessive ROS generation, inhibits activated caspase-3, caspase-9, cleaved PARP expression, and prevents neuronal apoptosis and cell death. 5,7-Dihydroxychromone increases LXRα and PPARγ mRNA expression, induces preadipocyte differentiation, and regulates blood glucose levels. 5,7-Dihydroxychromone inhibits radial growth of soil pathogenic fungi, radicle elongation of select seedlings, and transiently inhibits Bradyrhizobium sp. growth in high mannitol medium. 5,7-Dihydroxychromone can be used for the research of Parkinson’s disease, type 2 diabetes mellitus and pathogenic fungal infection .
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1
1 Cited Publications
Cat. No.: HY-N8393
CAS No.: 1355681-10-5
Ascr#18, an ascaroside, is a hormone of nematodes. Ascr#18 is expressed during nematode development. Ascr#18 increases resistance in Arabidopsis, tomato, potato and barley to viral, bacterial, oomycete, fungal and nematode infections .
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1
1 Cited Publications
Cat. No.: HY-W015580
CAS No.: 4695-62-9
(+)-Fenchone is an antibacterial agent. (+)-Fenchone interferes with bacterial fatty acid synthesis, disrupts fungal cell wall construction, and inhibits bacterial biofilm formation. (+)-Fenchone can be used in studies related to bacterial and fungal infections .
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1
1 Cited Publications
Cat. No.: HY-N11911
CAS No.: 14320-81-1
Synonyms: (-)-Verazine
Verazine ((-)-Verazine) is an anti-Fungal Agent that can be found in the dried roots and rhizoma of Veratrum maackii Regel. Verazine causes DNA damage in the cerebellum and cerebral cortex of mice in a dose-dependent manner. Verazine can be used in the study of fungal infections and neurological diseases .
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1
1 Cited Publications
Cat. No.: HY-119123A
Purity:  98.13%
Synonyms: LTX-109 trihydrochloride
Target:  

Fungal Bacterial

Research Areas:  

Infection

Voxvoganan (LTX-109) trihydrochloride, a topical antimicrobial, is highly effective against S. aureus with a MIC range of 2 to 4 μg/mL. Voxvoganan trihydrochloride can be used for the research of bacterial skin infections, fungal infections and nasal decolonisation of MRSA .
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1
1 Cited Publications
Cat. No.: HY-N3300
CAS No.: 480-33-1
Synonyms: (R)-Mellein
Mellein ((R)-Mellein) is an isocoumarin compound with antibacterial activity. Mellein inhibits the activity of HCV Protease, disrupts the cell wall of Xanthomonas sp., and acts as an insect trail pheromone. Mellein is applicable to research related to fungal infections, bacterial infections, and hepatitis C virus infections .
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1
1 Cited Publications
Cat. No.: HY-U00007A
CAS No.: 6935-63-3
Synonyms: Ba 2652 dihydrochloride; Stilbamidin dihydrochloride
Target:  

Fungal

Research Areas:  

Infection Cancer

Stilbamidine dihydrochloride is a diamidine compound derived from Stilbene and used chiefly in the form of its crystalline isethionate salt in treating various fungal infections.
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1
1 Cited Publications
Cat. No.: HY-129060
CAS No.: 119006-77-8
Purity:  99.34%
Target:  

Fungal

Research Areas:  

Infection

Flutrimazole is an imidazole antifungal with dual anti-inflammatory and antifungal activity. Flutrimazole shows scarce transdermal penetration. Flutrimazole has the advantageous in the research of topical fungal infections with an inflammatory component .
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1
1 Cited Publications
Cat. No.: HY-N10014
CAS No.: 22451-73-6
Bulnesol is a sesquiterpenoid that can be isolated from Salvia dorystaechas. Bulnesol inhibits the activity of Fusarium moniliforme with an EC50 value of 0.6 mg/mL. Bulnesol can be used for the research of fungal infection .
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1
1 Cited Publications
Cat. No.: HY-122943
CAS No.: 69120-07-6
Moracin D is a flavonoid that can be isolated from Morus alba. Moracin D induces cell apoptosis and shows hypoglycemic, antiadipogenic, antifungal and antitumor effects. Moracin D can be used for fungal infection and breast cancer research .
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1
1 Cited Publications
Cat. No.: HY-N6689
CAS No.: 6686-70-0
Destruxin A is a fungal cyclopeptide with insecticidal and antiviral activities. Destruxin A has a certain inhibitory effect on leukemia cells in vitro. Destruxin A can also specifically inhibit the innate immune response of Drosophila melanogaster, making the flies more susceptible to bacterial infections .
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1
1 Cited Publications
Cat. No.: HY-B2033
CAS No.: 53112-28-0
Research Areas:  

Infection

Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .
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