VEGFA - vascular endothelial growth factor A Gene
Also Known as VPF; VEGF; MVCD1
Species: Homo sapiens
About VEGFA
This gene has 26 transcripts (splice variants), 254 orthologues, 4 paralogues and is associated with 1 phenotype. Broad expression in thyroid (RPKM 146.9), prostate (RPKM 69.5) and 21 other tissues.
Summary
This gene is a member of the PDGF/VEGF growth factor family. It encodes a heparin-binding protein, which exists as a disulfide-linked homodimer. This growth factor induces proliferation and migration of vascular endothelial cells, and is essential for both physiological and pathological angiogenesis. Disruption of this gene in mice resulted in abnormal embryonic blood vessel formation. This gene is upregulated in many known tumors and its expression is correlated with tumor stage and progression. Elevated levels of this protein are found in patients with POEMS syndrome, also known as Crow-Fukase syndrome. Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been described. There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is antiangiogenic. Expression of some isoforms derived from the AUG start codon is regulated by a small upstream open reading frame, which is located within an internal ribosome entry site. The levels of VEGF are increased during Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), thus promoting inflammation by facilitating recruitment of inflammatory cells, and by increasing the level of angiopoietin II (Ang II), one of two products of the SARS-CoV-2 binding target, angiotensin-converting enzyme 2 (ACE2). In turn, Ang II facilitates the elevation of VEGF, thus forming a vicious cycle in the release of inflammatory cytokines. [provided by RefSeq, Jun 2020]
VEGFA Products (60)
| mRNA | Protein | Name |
|---|---|---|
| NM_001204385.2 | NP_001191314.1 | vascular endothelial growth factor A isoform r |
| NM_001025368.3 | NP_001020539.2 | vascular endothelial growth factor A isoform d |
| NM_001025366.3 | NP_001020537.2 | vascular endothelial growth factor A isoform a |
| NM_001171626.2 | NP_001165097.1 | vascular endothelial growth factor A isoform VEGF-A precursor |
| NM_001033756.3 | NP_001028928.1 | vascular endothelial growth factor A isoform g |
| NM_001204384.2 | NP_001191313.1 | vascular endothelial growth factor A isoform q precursor |
| NM_001171628.2 | NP_001165099.1 | vascular endothelial growth factor A isoform n precursor |
| NM_001171624.2 | NP_001165095.1 | vascular endothelial growth factor A isoform j precursor |
| NM_001317010.1 | NP_001303939.1 | vascular endothelial growth factor A isoform VEGF-Ax precursor |
| NM_001171625.2 | NP_001165096.1 | vascular endothelial growth factor A isoform k precursor |
| NM_001287044.2 | NP_001273973.1 | vascular endothelial growth factor A isoform s |
| NM_001171629.2 | NP_001165100.1 | vascular endothelial growth factor A isoform o precursor |
| NM_001025370.3 | NP_001020541.2 | vascular endothelial growth factor A isoform f |
| NM_001171622.2 | NP_001165093.1 | vascular endothelial growth factor A isoform h |
| NM_001171630.2 | NP_001165101.1 | vascular endothelial growth factor A isoform p precursor |
| NM_001025367.3 | NP_001020538.2 | vascular endothelial growth factor A isoform c |
| NM_003376.6 | NP_003367.4 | vascular endothelial growth factor A isoform b |
| NM_001171623.2 | NP_001165094.1 | vascular endothelial growth factor A isoform i precursor |
| NM_001025369.3 | NP_001020540.2 | vascular endothelial growth factor A isoform e |
| NM_001171627.2 | NP_001165098.1 | vascular endothelial growth factor A isoform m precursor |
| NM_001025370.3 | NP_001020541.2 | vascular endothelial growth factor A isoform f |
| NM_001025366.3 | NP_001020537.2 | vascular endothelial growth factor A isoform a |
| NM_001025369.3 | NP_001020540.2 | vascular endothelial growth factor A isoform e |
| NM_001171622.2 | NP_001165093.1 | vascular endothelial growth factor A isoform h |
| NM_001171625.2 | NP_001165096.1 | vascular endothelial growth factor A isoform k precursor |
| NM_001171626.2 | NP_001165097.1 | vascular endothelial growth factor A isoform VEGF-A precursor |
| NM_001171627.2 | NP_001165098.1 | vascular endothelial growth factor A isoform m precursor |
| NM_001317010.1 | NP_001303939.1 | vascular endothelial growth factor A isoform VEGF-Ax precursor |
| NM_001171628.2 | NP_001165099.1 | vascular endothelial growth factor A isoform n precursor |
| NM_001171630.2 | NP_001165101.1 | vascular endothelial growth factor A isoform p precursor |
| NM_001204385.2 | NP_001191314.1 | vascular endothelial growth factor A isoform r |
| NM_003376.6 | NP_003367.4 | vascular endothelial growth factor A isoform b |
| NM_001204384.2 | NP_001191313.1 | vascular endothelial growth factor A isoform q precursor |
| NM_001171624.2 | NP_001165095.1 | vascular endothelial growth factor A isoform j precursor |
| NM_001025367.3 | NP_001020538.2 | vascular endothelial growth factor A isoform c |
| NM_001171629.2 | NP_001165100.1 | vascular endothelial growth factor A isoform o precursor |
| NM_001025368.3 | NP_001020539.2 | vascular endothelial growth factor A isoform d |
| NM_001171623.2 | NP_001165094.1 | vascular endothelial growth factor A isoform i precursor |
| NM_001033756.3 | NP_001028928.1 | vascular endothelial growth factor A isoform g |
| NM_001287044.2 | NP_001273973.1 | vascular endothelial growth factor A isoform s |
| NM_001025366.3 | NP_001020537.2 | vascular endothelial growth factor A isoform a |
| NM_001025367.3 | NP_001020538.2 | vascular endothelial growth factor A isoform c |
| NM_001025368.3 | NP_001020539.2 | vascular endothelial growth factor A isoform d |
| NM_001025369.3 | NP_001020540.2 | vascular endothelial growth factor A isoform e |
| NM_001025370.3 | NP_001020541.2 | vascular endothelial growth factor A isoform f |
| NM_001033756.3 | NP_001028928.1 | vascular endothelial growth factor A isoform g |
| NM_001171622.2 | NP_001165093.1 | vascular endothelial growth factor A isoform h |
| NM_001171623.2 | NP_001165094.1 | vascular endothelial growth factor A isoform i precursor |
| NM_001171624.2 | NP_001165095.1 | vascular endothelial growth factor A isoform j precursor |
| NM_001171625.2 | NP_001165096.1 | vascular endothelial growth factor A isoform k precursor |
| NM_001171626.2 | NP_001165097.1 | vascular endothelial growth factor A isoform VEGF-A precursor |
| NM_001171627.2 | NP_001165098.1 | vascular endothelial growth factor A isoform m precursor |
| NM_001171628.2 | NP_001165099.1 | vascular endothelial growth factor A isoform n precursor |
| NM_001171629.2 | NP_001165100.1 | vascular endothelial growth factor A isoform o precursor |
| NM_001171630.2 | NP_001165101.1 | vascular endothelial growth factor A isoform p precursor |
| NM_001204384.2 | NP_001191313.1 | vascular endothelial growth factor A isoform q precursor |
| NM_001204385.2 | NP_001191314.1 | vascular endothelial growth factor A isoform r |
| NM_001287044.2 | NP_001273973.1 | vascular endothelial growth factor A isoform s |
| NM_001317010.1 | NP_001303939.1 | vascular endothelial growth factor A isoform VEGF-Ax precursor |
| NM_003376.6 | NP_003367.4 | vascular endothelial growth factor A isoform b |
| Cellular Component GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| part of VEGF-A complex |
IPI
IPI: Inferred from physical interaction
|
12207021 | GOA |
| located in adherens junction |
IDA
IDA: Inferred from direct assay
|
26598555 | GOA |
| located in cell surface |
IDA
IDA: Inferred from direct assay
|
17470632 | GOA |
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
17082651 | GOA |
| located in extracellular space |
IDA
IDA: Inferred from direct assay
|
9202027 | GOA |
| located in secretory granule |
IDA
IDA: Inferred from direct assay
|
17082651 | GOA |
VEGFA Protein Structure
PDGF: smart00141 (229 - 311)
VEGF_C: pfam14554 (346 - 394)
- 0
- 100
- 200
- 300
- 395 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
vascular endothelial growth factor A |
|
VEGFA Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | Verweise |
|---|---|---|---|---|---|---|---|
|
Intra
|
VEGFA | P15692 | KDR | Homo sapiens | P35968 | 16763549 | |
|
Intra
|
VEGFA | P15692 | VEGFA | Homo sapiens | P15692 | 12207021 | |
|
Intra
|
VEGFA | P15692 | NRP1 | Homo sapiens | O14786 | 16763549 | |
|
Intra
|
VEGFA | P15692 | VEGFA | Homo sapiens | P15692 | 12207021 | |
|
Intra
|
VEGFA | P15692 | VEGFA | Homo sapiens | P15692 | 12207021 | |
|
Intra
|
VEGFA | P15692 | VEGFA | Homo sapiens | P15692 | 25132001 | |
|
Intra
|
VEGFA | P15692 | NRP1 | Homo sapiens | O14786 | 16763549 | |
|
Intra
|
VEGFA | P15692 | FLT1 | Homo sapiens | P17948 | 9393862 | |
|
Intra
|
VEGFA | P15692 | FLT1 | Homo sapiens | P17948 | 33961781 |
Recombinant VEGFA Proteins
| Art. -Nr. | Produktname | Accession | Reinheit |
|---|---|---|---|
| HY-P7110 | VEGF165 Protein, Human (P.pastoris) | P15692-4 (A27-R191) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P7110A | VEGF165 Protein, Human (HEK293) | P15692-4 (A27-R191) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P7420 | VEGF121 Protein, Human (120 a.a) | P15692-9 (P28-R147) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P70519 | VEGF121 Protein, Human (HEK293, His) | P15692-9 (A27-R147) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P73471 | VEGF121 Protein, Human (HEK293) | P15692-9 (M1-R147) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P73556 | VEGF145 Protein, Human (HEK293, solution) | P15692-6 (A27-R171) | ≥ 90%, as determined by reducing SDS-PAGE. |
| HY-P77279 | VEGF183 Protein, Human (sf9) | P15692-3 (A27-R209) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P78228 | VEGF121 Protein, Human (Biotinylated, HEK293, His-Avi) | P15692-9 (A27-R147) | ≥ 95%, as determined by Bis-Tris PAGE. |
| HY-P78229 | VEGF165 Protein, Human (Biotinylated, HEK293, His-Avi) | P15692-4 (A27-R191) | ≥ 95%, as determined by Bis-Tris PAGE. |
| HY-P78377 | VEGF121 Protein, Human (HEK293, His-Avi) | P15692-9 (A27-R147) | ≥ 95%, as determined by Bis-Tris PAGE. |
| HY-P78378 | VEGF165 Protein, Human (HEK293, His-Avi) | P15692-4 (A27-R191) | ≥ 95%, as determined by Bis-Tris PAGE. |
| HY-P78813 | VEGF165 Protein, Human (Biotinylated, HEK293, Avi) | P15692-4/NP_001165097 (A27-R191) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P700157AF | Animal-Free VEGF165 Protein, Human (His) | P15692-4 (A27-R191) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P70458A | VEGF165 Protein, Human (HEK293, C-His) | P15692-4 (A27-R191) | ≥ 95%, as determined by reducing SDS-PAGE. |
VEGFA Antibodies
| Art. -Nr. | Produktname | Anwendung | Reactivity |
|---|---|---|---|
| HY-P80929 | VEGFA Antibody (YA013) | WB | Human, Mouse, Rat |
| HY-P80929A | VEGFA Antibody (YA013)(PBS only) | WB | Human, Mouse, Rat |
| HY-P84117 | VEGFA Antibody (YA3814) | WB, ICC/IF, ELISA | Human |
| HY-P84117A | VEGFA Antibody (YA3814)(PBS only) | WB, ICC/IF, ELISA | Human |
| HY-P85795 | VEGFA Antibody (YA5487) | WB, ICC/IF, ELISA | Human, Mouse, Rat |
| HY-P86376 | VEGFA Antibody (YA6068) | WB, IHC-P, ICC/IF, ELISA | Human, Mouse, Rat |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Microvascular Complications Of Diabetes 1 |
|
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| Poems Syndrome |
|
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| Diabetic Macular Edema |
|
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| Retinal Vein Occlusion |
|
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| Corneal Neovascularization |
|
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| Ischemia |
|
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| Neovascular Glaucoma |
|
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| Central Retinal Vein Occlusion |
|
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| Retinal Vascular Disease |
|
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| Macular Retinal Edema |
|
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| Ovarian Hyperstimulation Syndrome |
|
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| Diabetic Neuropathy |
|
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| Vascular Cancer |
|
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| Microvascular Complications Of Diabetes 5 |
|
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| Retinal Ischemia |
|
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| End Stage Renal Disease |
|
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| Kuhnt-Junius Degeneration |
|
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| Hemangioma |
|
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| Angiodysplasia |
|
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| Preretinal Fibrosis |
|
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| Osteonecrosis |
|
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| Background Diabetic Retinopathy |
|
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| Leukostasis |
|
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| Von Hippel-Lindau Syndrome |
|
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| Severe Nonproliferative Diabetic Retinopathy |
|
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| Retinal Detachment |
|
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| Adenocarcinoma |
|
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| Trachoma |
|
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| Rubeosis Iridis |
|
|
| Vascular Disease |
|
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| Adenomyosis |
|
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| Capillary Leak Syndrome |
|
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| Rosacea |
|
|
| Intermittent Claudication |
|
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| Varicose Veins |
|
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| Blood Group, Globoside System |
|
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| Malignant Pleural Mesothelioma |
|
|
| Acute Endophthalmitis |
|
|
| Venous Insufficiency |
|
|
| Viral Encephalitis |
|
|
| Hydrocele |
|
|
| Tongue Carcinoma |
|
|
| Macular Degeneration, Age-Related, 1 |
|
|
| Branch Retinal Artery Occlusion |
|
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| Colorectal Cancer |
|
|
| Macular Dystrophy, Dominant Cystoid |
|
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| Purulent Endophthalmitis |
|
|
| Pre-Eclampsia |
|
|
| Placental Insufficiency |
|
|
| Vascular Dementia |
|
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| Retinal Vascular Occlusion |
|
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| Pancreatic Adenocarcinoma |
|
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| Proctitis |
|
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| Brain Edema |
|
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| Squamous Cell Carcinoma |
|
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| Retinal Perforation |
|
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| Endometrial Cancer |
|
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| Lymphangioma |
|
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| Endometriosis |
|
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| Degenerative Myopia |
|
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| Pericardial Effusion |
|
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| Cystadenocarcinoma |
|
|
| Hepatic Veno-Occlusive Disease |
|
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| Pancreatic Cancer |
|
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| Hemifacial Spasm |
|
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| Hepatopulmonary Syndrome |
|
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| Coats Disease |
|
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| Hemangioblastoma |
|
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| Placenta Accreta |
|
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| Laryngeal Squamous Cell Carcinoma |
|
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| Nodular Goiter |
|
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| Glioblastoma |
|
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| Pancreatic Ductal Carcinoma |
|
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| Vein Disease |
|
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| Mucositis |
|
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| Lung Cancer |
|
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| Lens Disease |
|
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| Acute Chest Syndrome |
|
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| Vitreous Detachment |
|
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| Chorioretinal Scar |
|
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| Nephrosclerosis |
|
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| Angiosarcoma |
|
|
| Degeneration Of Macula And Posterior Pole |
|
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| Retinal Microaneurysm |
|
|
| Limb Ischemia |
|
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| Renal Cell Carcinoma, Nonpapillary |
|
|
| Central Serous Chorioretinopathy |
|
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| Bladder Cancer |
|
|
| Eclampsia |
|
|
| Vitreous Disease |
|
|
| Kaposi Sarcoma |
|
|
| Carpal Tunnel Syndrome |
|
|
| Merkel Cell Carcinoma |
|
|
| Breast Disease |
|
|
| Hypoglycemia |
|
|
| Nonarteritic Anterior Ischemic Optic Neuropathy |
|
|
| Optic Neuritis |
|
|
| Exudative Vitreoretinopathy 1 |
|
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| Breast Cancer |
|
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| Carotid Stenosis |
|
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| Kidney Cancer |
|
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| Impotence |
|
|
| Sick Building Syndrome |
|
|
| Osteosclerotic Myeloma |
|
|
| Ovarian Cancer |
|
|
| Pulmonary Emphysema |
|
|
| Anaplastic Astrocytoma |
|
|
| Neuropathy |
|
|
| Pyogenic Granuloma |
|
|
| Chorioamnionitis |
|
|
| Gastric Ulcer |
|
|
| Capillary Disease |
|
|
| Pulmonary Hypertension |
|
|
| Endophthalmitis |
|
|
| Eye Degenerative Disease |
|
|
| Hematologic Cancer |
|
|
| Fallopian Tube Carcinoma |
|
|
| Lymphangioleiomyomatosis |
|
|
| Diabetes Mellitus |
|
|
| Bile Duct Cancer |
|
|
| Hellp Syndrome |
|
|
| Oral Submucous Fibrosis |
|
|
| Histoplasmosis Retinitis |
|
|
| Gastrointestinal Stromal Tumor |
|
|
| Plantar Fasciitis |
|
|
| Plasmacytoma |
|
|
| Pseudoxanthoma Elasticum |
|
|
| Brain Cancer |
|
|
| Orbital Tenonitis |
|
|
| Sleep Apnea |
|
|
| Hydronephrosis |
|
|
| Oligodendroglioma |
|
|
| Cardiovascular Organ Benign Neoplasm |
|
|
| Gastric Cancer |
|
|
| Neurofibroma |
|
|
| Cystitis |
|
|
| Endometrial Hyperplasia |
|
|
| Sudden Infant Death Syndrome |
|
|
| Hepatocellular Carcinoma |
|
|
| Angioid Streaks |
|
|
| Polycythemia |
|
|
| Synovitis |
|
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| Macular Holes |
|
|
| Central Retinal Artery Occlusion |
|
|
| Neuroendocrine Tumor |
|
|
| Uveitis |
|
|
| Neuritis |
|
|
| Cervical Squamous Cell Carcinoma |
|
|
| Capillary Hemangioma |
|
|
| Goiter |
|
|
| Leiomyosarcoma |
|
|
| Craniopharyngioma |
|
|
| Hypopyon |
|
|
| Hereditary Hemorrhagic Telangiectasia |
|
|
| Retinal Hemangioblastoma |
|
|
| Hypertensive Retinopathy |
|
|
| Retinal Artery Occlusion |
|
|
| Ichthyosis, Congenital, Autosomal Recessive 11 |
|
|
| Eye Disease |
|
|
| Psoriatic Arthritis |
|
|
| Tetralogy Of Fallot |
|
|
| Intussusception |
|
|
| Bacillary Angiomatosis |
|
|
| Gingivitis |
|
|
| Choroiditis |
|
|
| Tuberous Sclerosis |
|
|
| Rheumatoid Arthritis |
|
|
| Systemic Scleroderma |
|
|
| Osteonecrosis Of The Jaw |
|
|
| Gastroesophageal Junction Adenocarcinoma |
|
|
| Congestive Heart Failure |
|
|
| High Grade Glioma |
|
|
| Buerger Disease |
|
|
| Fabry Disease |
|
|
| Retinal Disease |
|
|
| Vitreoretinopathy |
|
|
| Myelofibrosis |
|
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| Thymoma |
|
|
| Sensory System Disease |
|
|
| Wallerian Degeneration |
|
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| Carcinoid Syndrome |
|
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| Bronchitis |
|
|
| Hypertensive Encephalopathy |
|
|
| Combined Immunodeficiency |
|
|
| Liposarcoma |
|
|
| Varicocele |
|
|
| Schistosomiasis |
|
|
| Meningitis |
|
|
| Central Nervous System Hemangioma |
|
|
| Chordoma |
|
|
| Prostate Cancer |
|
|
| Papilloma |
|
|
| Gastroesophageal Adenocarcinoma |
|
|
| Glomeruloid Hemangioma |
|
|
| Motor Neuron Disease |
|
|
| Ovarian Disease |
|
|
| Acute Myocardial Infarction |
|
|
| Decubitus Ulcer |
|
|
| Digeorge Syndrome |
|
|
| Prostate Angiosarcoma |
|
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| Malaria |
|
|
| Papilledema |
|
|
| Adenoid Cystic Carcinoma |
|
|
| Transitional Cell Carcinoma |
|
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| Supratentorial Meningioma |
|
|
| Heart Disease |
|
|
| Lung Disease |
|
|
| Lung Non-Squamous Non-Small Cell Carcinoma |
|
|
| Anemia Of Prematurity |
|
|
| Posterior Scleritis |
|
|
| Scotoma |
|
|
| Myopia |
|
|
| Refractive Error |
|
|
| Arthrogryposis Multiplex Congenita-4 |
|
|
| Aortic Aneurysm |
|
|
| Epicondylitis |
|
|
| Polycystic Kidney Disease |
|
|
| Hydrocephalus |
|
|
| Choroid Cancer |
|
|
| Cerebral Artery Occlusion |
|
|
| Temporal Arteritis |
|
|
| Lymphangiosarcoma |
|
|
| Peripheral Vascular Disease |
|
|
| Splenomegaly |
|
|
| Neuroretinitis |
|
|
| Iridocyclitis |
|
|
| Severe Combined Immunodeficiency |
|
|
| Telangiectasis |
|
|
| Blood Protein Disease |
|
|
| Corneal Disease |
|
|
| Type 1 Diabetes Mellitus |
|
|
| Pheochromocytoma |
|
|
| Danubian Endemic Familial Nephropathy |
|
|
| Acquired Hemangioma |
|
|
| Squamous Cell Carcinoma, Head And Neck |
|
|
| Hepatoblastoma |
|
|
| Skin Carcinoma |
|
|
| Peripheral Artery Disease |
|
|
| Thyroid Gland Cancer |
|
|
| Retinal Telangiectasia |
|
|
| Uveal Disease |
|
|
| Melanoma |
|
|
| Arteriovenous Malformation |
|
|
| Keratitis, Hereditary |
|
|
| Hepatic Vascular Disease |
|
|
| Chorioretinitis |
|
|
| Polycythemia Vera |
|
|
| Gorham'S Disease |
|
|
| Retinal Vasculitis |
|
|
| Colon Adenocarcinoma |
|
|
| Cataract |
|
|
| Intestinal Perforation |
|
|
| Insulin-Like Growth Factor I |
|
|
| Ischemic Bone Disease |
|
|
| Cavernous Hemangioma |
|
|
| Myocardial Infarction |
|
|
| Chronic Ulcer Of Skin |
|
|
| Acute Retinal Necrosis Syndrome |
|
|
| Scleral Disease |
|
|
| Posterior Uveitis |
|
|
| Multicentric Castleman Disease |
|
|
| Tendinitis |
|
|
| Intracranial Meningioma |
|
|
| Hypothyroidism |
|
|
| Acute Closed-Angle Glaucoma |
|
|
| Bartonellosis |
|
|
| Keratopathy |
|
|
| Vitreoretinopathy, Neovascular Inflammatory |
|
|
| Radiation Cystitis |
|
|
| Kidney Disease |
|
|
| Panuveitis |
|
|
| Diabetic Polyneuropathy |
|
|
| Hantavirus Pulmonary Syndrome |
|
|
| Corneal Edema |
|
|
| Rhabdomyosarcoma |
|
|
| Lung Cancer Susceptibility 3 |
|
|
| Exanthem |
|
|
| Thrombocytopenia |
|
|
| Androgenic Alopecia |
|
|
| Hypertension, Essential |
|
|
| Iritis |
|
|
| Corneal Ulcer |
|
|
| Diabetic Angiopathy |
|
|
| Huntington Disease |
|
|
| Myelodysplastic Syndrome |
|
|
| Ischemic Neuropathy |
|
|
| Reproductive Organ Benign Neoplasm |
|
|
| Myeloma, Multiple |
|
|
| Osteoporosis |
|
|
| Mild Pre-Eclampsia |
|
|
| Choroid Disease |
|
|
| Fallopian Tube Disease |
|
|
| Severe Pre-Eclampsia |
|
|
| Moyamoya Disease 1 |
|
|
| Down Syndrome |
|
|
| Uterine Benign Neoplasm |
|
|
| Anterior Uveitis |
|
|
| Nasopharyngeal Carcinoma |
|
|
| Punctate Epithelial Keratoconjunctivitis |
|
|
| Castleman Disease |
|
|
| Gallbladder Cancer |
|
|
| Nephrotic Syndrome |
|
|
| Angiokeratoma Circumscriptum |
|
|
| Neuroblastoma |
|
|
| Adhesions Of Uterus |
|
|
| Hair Disease |
|
|
| Patellar Tendinitis |
|
|
| Intraocular Pressure Quantitative Trait Locus |
|
|
| Steroid-Induced Glaucoma |
|
|
| Breast Adenocarcinoma |
|
|
| Carotid Artery Occlusion |
|
|
| Medulloblastoma |
|
|
| Hantavirus Hemorrhagic Fever With Renal Syndrome |
|
|
| Lipoprotein Quantitative Trait Locus |
|
|
| Narcolepsy |
|
|
| Integumentary System Disease |
|
|
| Leukocyte Disease |
|
|
| Systemic Lupus Erythematosus |
|
|
| Blood Coagulation Disease |
|
|
| Type 2 Diabetes Mellitus |
|
|
| Exudative Vitreoretinopathy |
|
|
| Pulmonary Artery Disease |
|
|
| Blood Platelet Disease |
|
|
| Psoriasis |
|
|
| Persistent Fetal Circulation Syndrome |
|
|
| Conjunctival Vascular Disease |
|
|
| Arteriovenous Malformations Of The Brain |
|
|
| Apnea, Obstructive Sleep |
|
|
| Malignant Ovarian Surface Epithelial-Stromal Neoplasm |
|
|
| Occlusion Precerebral Artery |
|
|
| Pulmonary Adenocarcinoma In Situ |
|
|
| Breast Carcinoma In Situ |
|
|
| Pre-Malignant Neoplasm |
|
|
| Esophageal Cancer |
|
|
| Central Nervous System Benign Neoplasm |
|
|
| Ductal Carcinoma In Situ |
|
|
| Pleural Disease |
|
|
| Arteries, Anomalies Of |
|
|
| Placenta Disease |
|
|
| Vogt-Koyanagi-Harada Disease |
|
|
| Intestinal Benign Neoplasm |
|
|
| Cranial Nerve Disease |
|
|
| Asthma |
|
|
| Encephalomalacia |
|
|
| Childhood Angiosarcoma |
|
|
| Pleural Cancer |
|
|
| Colorectal Adenocarcinoma |
|
|
| Bone Inflammation Disease |
|
|
| Brain Glioma |
|
|
| Spinal Cord Disease |
|
|
| Oropharynx Cancer |
|
|
| Cell Type Benign Neoplasm |
|
|
| Acquired Color Blindness |
|
|
| Bone Marrow Cancer |
|
|
| In Situ Carcinoma |
|
|
| Rectal Disease |
|
|
| Anaplastic Oligodendroglioma |
|
|
| Aortic Valve Disease 1 |
|
|
| Ovary Epithelial Cancer |
|
|
| Persistent Hyperplastic Primary Vitreous |
|
|
| Congenital Granular Cell Tumor |
|
|
| Autonomic Nervous System Neoplasm |
|
|
| Macular Dystrophy, Patterned, 3 |
|
|
| Peripheral Nervous System Neoplasm |
|
|
| Autoimmune Disease Of Musculoskeletal System |
|
|
| Colonic Benign Neoplasm |
|
|
| Gastrointestinal System Benign Neoplasm |
|
|
| Ulcer Of Lower Limbs |
|
|
| Low Grade Glioma |
|
|
| Amblyopia |
|
|
| Peripheral Nervous System Disease |
|
|
| Klippel-Trenaunay-Weber Syndrome |
|
|
| Ovary Adenocarcinoma |
|
|
| Large Cell Carcinoma With Rhabdoid Phenotype |
|
|
| Retinitis Pigmentosa 50 |
|
|
| Cholangiocarcinoma |
|
|
| Optic Nerve Disease |
|
|
| Cystic Fibrosis |
|
|
| Patent Ductus Arteriosus 1 |
|
|
| Head And Neck Cancer |
|
|
| Glaucoma, Primary Open Angle |
|
|
| Malignant Astrocytoma |
|
|
| Suppression Of Tumorigenicity 12 |
|
|
| Renal Cell Carcinoma, Papillary, 1 |
|
|
| Gliosarcoma |
|
|
| Amelogenesis Imperfecta, Type Ig |
|
|
| Breast Leiomyosarcoma |
|
|
| Plantar Fascial Fibromatosis |
|
|
| Gallbladder Disease |
|
|
| Respiratory Failure |
|
|
| Cervix Carcinoma |
|
|
| Premature Menopause |
|
|
| Melanoma, Uveal |
|
|
| Interstitial Lung Disease 2 |
|
|
| Thyroid Gland Anaplastic Carcinoma |
|
|
| Norrie Disease |
|
|
| Aortic Aneurysm, Familial Abdominal, 1 |
|
|
| Autosomal Recessive Congenital Ichthyosis |
|
|
| Stroke, Ischemic |
|
|
| Nervous System Disease |
|
|
| Diaphragmatic Hernia, Congenital |
|
|
| Connective Tissue Disease |
|
|
| Skin Disease |
|
|
| Meningioma, Familial |
|
|
| Wilms Tumor 1 |
|
|
| Bilirubin Metabolic Disorder |
|
|
| Behcet Syndrome |
|
|
| Chromophobe Renal Cell Carcinoma |
|
|
| Lynch Syndrome |
|
|
| Amelogenesis Imperfecta |
|
|
| Intracranial Berry Aneurysm |
|
|
| Brittle Bone Disorder |
|
|
| Deficiency Anemia |
|
|
| Leukemia, Acute Myeloid |
|
|
| Migraine With Or Without Aura 1 |
|
|
| Body Mass Index Quantitative Trait Locus 11 |
|
|
| Amyotrophic Lateral Sclerosis 1 |
|
|
| Leukemia, Chronic Lymphocytic |
|
|
| Aortic Aneurysm, Familial Thoracic 1 |
|
|
| Dilated Cardiomyopathy |
|
|
| Fundus Dystrophy |
|
|
| Leber Plus Disease |
|
|
| Retinitis Pigmentosa |
|
|
| Cone-Rod Dystrophy 2 |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | VEGFA | VGNC | VGNC:83966 |
| Bos taurus | VEGFA | VGNC | VGNC:55927 |
| Canis familiaris | VEGFA | VGNC | VGNC:48250 |
| Rattus norvegicus | VEGFA | RGD | RGD:619991 |
| Felis catus | VEGFA | VGNC | VGNC:66936 |
| Mus musculus | VEGFA | MGD | MGI:103178 |
| Others | VEGFA | NCBI |