N-Desmethyl clomipramine-d6
N-Desmethyl clomipramine-d6 (Desmethylclomipramine-d6) is deuterium labeled N-Desmethyl clomipramine. Desmethylclomipramine (Norclomipramine) is a metabolite of Clomipramine (HY-B0457A) and can be used for neurological research.
For research use only. We do not sell to patients.
- Formula: C18H15D6ClN2
- Molecular Weight:306.86
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 303-48-0
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Molecular Weight 306.86
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Formula C18H15D6ClN2
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SMILES
CNC([2H])([2H])C([2H])([2H])C([2H])([2H])N1C2=CC(Cl)=CC=C2CCC3=CC=CC=C31
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Synonyms
Desmethylclomipramine-d6; Norclomipramine-d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Coulter C, et al. Antidepressant drugs in oral fluid using liquid chromatography-tandem mass spectrometry. J Anal Toxicol. 2010 Mar;34(2):64-72. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-Desmethyl clomipramine-d6 Related Classifications
HY-12388S1 Related Classifications
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