2. Gene
  3. Il4 - interleukin 4 Gene

Il4 - interleukin 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Il4e12

Gene ID: 287287 | Gene type: protein coding

About Il4

Primary_assembly 10: 37,771,203-37,776,750 reverse strand.mRatBN7.2:CM026983.1

This gene has 1 transcript (splice variant), 92 orthologues and is associated with 113 phenotypes. Low expression observed in reference dataset.

Summary

Predicted to enable cytokine activity. Involved in several processes, including positive regulation of biosynthetic process; positive regulation of leukocyte migration; and regulation of defense response. Located in extracellular space. Used to study anti-basement membrane glomerulonephritis; autoimmune thyroiditis; and pelvic inflammatory disease. Biomarker of several diseases, including cerebrovascular disease (multiple); interstitial lung disease (multiple); irritant dermatitis; primary biliary cholangitis; and rhinitis (multiple). Human ortholog(s) of this gene implicated in several diseases, including asthma (multiple); autoimmune disease (multiple); hepatitis B; hepatitis C; and pancreatic Cancer (multiple). Orthologous to human IL4 (interleukin 4). [provided by Alliance of Genome Resources, Apr 2022]

Il4 Products(1)

mRNA Protein Name
NM_201270.1 NP_958427.1 interleukin-4 precursor

Il4 Protein Structure

IL4_13

IL4_13: smart00190 (0 - 143)

  • 0
  • 100
  • 147 a.a.
Protein Preferred Names Protein Names

interleukin-4

B-cell IGG differentiation factor

B-cell growth factor 1

B-cell stimulatory factor 1

BSF-1

IL-4

lymphocyte stimulatory factor 1

Recombinant Il4 Proteins

Cat. No. Product Name Accession Purity
HY-P7101 IL-4 Protein, Rat P20096 /
HY-P7101A IL-4 Protein, Rat (CHO, His) P20096 ≥95%

Related Agents

Approval
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0446 Naphazoline hydrochloride 98.37% Unkown
HY-17002 Suplatast (Tosilate) Inhibitor 98.33% Unkown
HY-108013 Armillarisin A 99.80% Unkown
HY-111326A Naphazoline nitrate ≥98.0% Unkown
HY-111326 Naphazoline / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P9926 Dupilumab Inhibitor ≥99.2% Unkown
Clinical Phase
Inhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Phase
HY-P990093 Stapokibart Inhibitor 96.34% Phase 3
HY-P990090 Rademikibart Inhibitor / Phase 3
HY-P99724 Manfidokimab 95.00% Phase 2
HY-P99883 Romilkimab / Phase 2
Pre-clinical Phase
Bioactive Molecules (21)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N0527 Pentagalloylglucose Inhibitor 99.77% Unkown
HY-134771 YM-341619 Inhibitor 99.06% Unkown
HY-139092 IL-4-inhibitor-1 Inhibitor 98.14% Unkown
HY-126360 Oxazolone ≥98.0% Unkown
HY-N0600 Ginsenoside F3 Modulator 99.84% Unkown
HY-N3312 Matairesinol ≥98.0% Unkown
HY-N7652 Terminolic acid Inhibitor 99.63% Unkown
HY-15131 PNRI-299 Inhibitor / Unkown
HY-N2426 Clerodendrin Inhibitor 99.66% Unkown
HY-144683 PF-07038124 Inhibitor / Unkown
HY-116609 C6 L-threo Ceramide Inhibitor / Unkown
HY-125019 iJak-381 Inhibitor / Unkown
HY-141582 Ceramide 3 / Unkown
HY-144684 PDE4-IN-8 Inhibitor / Unkown
HY-155951 JAK3-IN-14 Inhibitor 99.32% Unkown
HY-162248 JAK1/2-IN-1 Inhibitor / Unkown
HY-RS06765 IL4 Human Pre-designed siRNA Set A / Unkown
HY-RS06766 Il4 Mouse Pre-designed siRNA Set A / Unkown
HY-RS06767 Il4 Rat Pre-designed siRNA Set A / Unkown
HY-RS06768 IL4I1 Human Pre-designed siRNA Set A / Unkown
HY-RS06769 IL4R Human Pre-designed siRNA Set A / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99238 Rolinsatamab Inhibitor 97.16% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il4 NCBI NCBI:3565
Macaca fascicularis Il4 NCBI NCBI:107130068
Mus musculus Il4 NCBI NCBI:16189
Susscrofa domestica Il4 NCBI
Macaca mulatta Il4 NCBI NCBI:574281