MMP2 - matrix metallopeptidase 2 Gene

Species: Bos taurus

Gene Type: protein coding
Gene ID: 282872

About MMP2

Primary_assembly 18: 23,752,891-23,780,118 forward strand.ARS-UCD1.2:CM008185.2

This gene has 2 transcripts (splice variants), 210 orthologues and 21 paralogues.

MMP2 Products (1)

mRNA Protein Name
NM_174745.2 NP_777170.1 72 kDa type IV collagenase precursor

MMP2 Protein Structure

PG_binding_1

PG_binding_1: pfam01471 (70 - 97)

Peptidase_M10

Peptidase_M10: pfam00413 (118 - 446)

FN2

FN2: smart00059 (226 - 274)

FN2

FN2: smart00059 (284 - 332)

FN2

FN2: smart00059 (342 - 390)

HX

HX: cd00094 (466 - 660)

  • 0
  • 200
  • 400
  • 600
  • 661 a.a.
Protein Preferred Names Protein Names

72 kDa type IV collagenase

  • 72 kDa gelatinase

  • MMP-2

  • matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

  • matrix metalloproteinase 2 (72 KDa type IV collagenase)

  • matrix metalloproteinase-2

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0493 Niflumic acid Inhibitor 99.61% Unkown
HY-B0689A Indinavir sulfate 99.97% Yes
HY-B0689 Indinavir 99.96% Yes
HY-B0493R Niflumic acid (Standard) Inhibitor 99.93% Unkown
HY-B0689B Indinavir sulfate ethanolate / Unkown

Clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Phase
HY-12169 Marimastat Inhibitor 99.81% Phase 3
HY-12170 Prinomastat 98.41% Phase 3
HY-12170A Prinomastat hydrochloride 98.53% Phase 3
HY-B0916 Propoxur 99.43% Phase 3
HY-15768 Ilomastat Inhibitor 99.14% Phase 2
HY-10398 CTS-1027 Inhibitor 99.24% Phase 2
HY-106992 S 3304 Inhibitor 99.75% Phase 2
HY-112160 XL-784 free base Inhibitor / Phase 2
HY-160822 AGG-523 Inhibitor 99.32% Phase 1
HY-114214 CKD-712 / Phase 1
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991419 MSB-0254 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (148)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0431 Astragaloside IV Inhibitor 99.93% Unkown
HY-13564 Batimastat Inhibitor 98.92% Unkown
HY-12354 SB-3CT Inhibitor 99.84% Unkown
HY-122022 JR-AB2-011 Inhibitor 98.15% Unkown
HY-110397 KP-457 Inhibitor 99.18% Unkown
HY-W068119A N-(2-Aminoethyl)maleimide hydrochloride 99.97% Unkown
HY-122214 AC-73 Inducer 99.91% Unkown
HY-N0069 Solamargine 99.87% Unkown
HY-103444 ARP-100 Inhibitor ≥99.0% Unkown
HY-N0532 Morroniside Inhibitor 99.94% Unkown
HY-N2593 Isorhapontigenin 99.82% Unkown
HY-W591424 m-PEG2000-NHS ester Ligand 95.89% Unkown
HY-N0805 Alisol B 23-acetate 99.65% Unkown
HY-112546 MMP-2 Inhibitor I Inhibitor 99.24% Unkown
HY-N0853 Alisol A 99.59% Unkown
HY-107394 UK 356618 Inhibitor 98.91% Unkown
HY-124373 ND-336 Inhibitor 97.16% Unkown
HY-164159 α-Glucosylrutin Inhibitor 96.32% Unkown
HY-120149 Inotodiol 98.29% Unkown
HY-144707 AK-778-XXMU 99.96% Unkown
HY-N0249 Saikosaponin C Inducer 98.09% Unkown
HY-N0419 Quercimeritrin 99.48% Unkown
HY-146754 MMP2-IN-1 99.24% Unkown
HY-113440 5-Methoxytryptophol 99.95% Unkown
HY-128393 Trilinolein 98.0% Unkown
HY-124813 PDZ1i Inhibitor 99.29% Unkown
HY-162038 RXP03 Inhibitor 98.82% Unkown
HY-N0084 Betulinaldehyde Inhibitor 98.72% Unkown
HY-P3513 β-Neo-Endorphin Activator 98.97% Unkown
HY-N0566 23-Hydroxybetulinic acid 99.44% Unkown
HY-107639 UK-370106 Inhibitor ≥99.0% Unkown
HY-116474 Viridicatol 99.93% Unkown
HY-N7627 Regaloside C 99.62% Unkown
HY-P2213 GPLGIAGQ Inducer 99.74% Unkown
HY-116399 MMP-2/MMP-9-IN-1 Inhibitor 99.48% Unkown
HY-12168 Tanomastat Inhibitor 99.74% Unkown
HY-107428 PD-166793 Inhibitor 99.21% Unkown
HY-117970 MMPI-1154 Inhibitor 99.76% Unkown
HY-122506 Salviolone Inhibitor 99.32% Unkown
HY-W001925 7-Methoxy-1-tetralone 99.93% Unkown
HY-101535 ARP101 Inhibitor ≥99.0% Unkown
HY-110397G KP-457 (GMP) Inhibitor / Unkown
HY-120213 YH-306 98.34% Unkown
HY-19485 XL-784 Inhibitor 98.25% Unkown
HY-W011085 CP-471474 Inhibitor 99.2% Unkown
HY-143657 Myoferlin inhibitor 1 Inhibitor 99.88% Unkown
HY-P2213A GPLGIAGQ TFA Inducer 99.89% Unkown
HY-148571 TP0597850 Inhibitor 99.09% Unkown
HY-114785 BPHA Inhibitor 99.88% Unkown
HY-126941 Hecogenin acetate 98.57% Unkown
HY-176184 PROTAC DDR1 degrader-1 98.69% Unkown
HY-N5136 25(R,S)-Ruscogenin Inhibitor 99.83% Unkown
HY-N6896 Isoviolanthin Inhibitor 99.87% Unkown
HY-P10143 MMP-2/MMP-9 Substrate Substrate 98.48% Unkown
HY-114911 Feprazone Inhibitor 99.88% Unkown
HY-119979 Cardanol monoene Inducer 98.02% Unkown
HY-147745 MMP2-IN-2 Inhibitor 98.80% Unkown
HY-181654 Snail IN-1 Inhibitor 98.27% Unkown
HY-N7385 Nudol 99.60% Unkown
HY-P0273A Histatin 5 TFA Inhibitor 99.98% Unkown
HY-13564A Batimastat sodium salt Inhibitor 99.04% Unkown
HY-N16129 Diplacone 98.38% Unkown
HY-110116 SD-2590 hydrochloride Inhibitor 99.4% Unkown
HY-120349 LL-Z1640-4 Inhibitor 99.0% Unkown
HY-130076 MMP-2 Inhibitor II Inhibitor 98.0% Unkown
HY-131417 cis-ACCP Inhibitor 97.0% Unkown
HY-147031 JAMM protein inhibitor 2 Inhibitor 98.20% Unkown
HY-147746 MMP2-IN-3 Inhibitor 99.64% Unkown
HY-P1789A CTTHWGFTLC, CYCLIC TFA Inhibitor 98.52% Unkown
HY-160187A (Rac)-AAA 99.02% Unkown
HY-RS08537 MMP2 Human Pre-designed siRNA Set A / Unkown
HY-77813S Benzyl isothiocyanate-d7 / Unkown
HY-105854 Pipoxolan hydrochloride / Unkown
HY-109747 RO-28-2653 Inhibitor / Unkown
HY-111172 Inotilone Inhibitor 95.26% Unkown
HY-113621B Ageladine A dihydrochloride Inhibitor / Unkown
HY-114396 BR351 Inhibitor / Unkown
HY-116474R Viridicatol (Standard) / Unkown
HY-119185 AZD-6605 / Unkown
HY-120339 STK899704 / Unkown
HY-12168B (Rac)-Tanomastat Inhibitor / Unkown
HY-124373A (R)-ND-336 Inhibitor / Unkown
HY-128393S2 Trilinolein-d5 / Unkown
HY-136699 Excisanin A Inhibitor / Unkown
HY-138195 NEO212 / Unkown
HY-14237 SC-77964 Inhibitor / Unkown
HY-143407 FAK-IN-3 Inhibitor / Unkown
HY-147867 MMP-2/9-IN-1 Inhibitor / Unkown
HY-147936 TP0556351 Inhibitor / Unkown
HY-149378 MMP13-IN-5 Inhibitor / Unkown
HY-152030 Tubulin/MMP-IN-2 / Unkown
HY-154698 Homouridine / Unkown
HY-155201 YJ182 Inhibitor / Unkown
HY-155721 22-(4′-py)-JA Inhibitor / Unkown
HY-156247 IVMT-Rx-3 Inhibitor / Unkown
HY-15668 ST09 / Unkown
HY-157382 AChE-IN-51 Inhibitor / Unkown
HY-160720 ASPH-IN-1 Inhibitor / Unkown
HY-161707 MMP2-IN-4 Inhibitor / Unkown
HY-162344 Ir-CA Inducer / Unkown
HY-165386 TU-100 Inhibitor / Unkown
HY-168560 MMP Inhibitor 4 Inhibitor / Unkown
HY-168605 DH-18 / Unkown
HY-170604 MMP-2 Inhibitor-4 Inhibitor / Unkown
HY-171776 OPB-3206 Inhibitor / Unkown
HY-172088 Tubulin/MMP-IN-3 / Unkown
HY-172551 anti-TNBC agent-9 / Unkown
HY-175291 Cystatin B agonist 1 / Unkown
HY-175815 Apoptosis inducer 44 / Unkown
HY-176149 Fluoxetine-Conjugated Platinum(IV) prodrug-1 / Unkown
HY-180117 MMP-2/9-IN-2 / Unkown
HY-180765 Colchicine-O-CO-Enyl(Me)-Enyl-Enyl(Me)-Enyl-1,3,3-trimethylcyclohex-1-ene Activator / Unkown
HY-181272 MMP-9-IN-14 / Unkown
HY-182795 Colchicine derivative-1 / Unkown
HY-18694 CGS 27023A Inhibitor / Unkown
HY-18694A CGS 27023A free base Inhibitor / Unkown
HY-B0916R Propoxur (Standard) 99.04% Unkown
HY-B0916S Propoxur-d3 / Unkown
HY-N10176 D-Isofloridoside Inhibitor 98.59% Unkown
HY-N15588 Smyrindiol Inhibitor / Unkown
HY-N17617 S-Petasin / Unkown
HY-P11746 GPLGIAGQC / Unkown
HY-P1789 CTTHWGFTLC, CYCLIC Inhibitor / Unkown
HY-P3477 Mca-PLA-Nva-Dap(Dnp)-AR-NH2 / Unkown
HY-P3513A β-Neo-Endorphin acetate Activator / Unkown
HY-P3699 TNO003 Substrate / Unkown
HY-P4574 VPLSLYSG / Unkown
HY-P5764 TRAP-14 amide / Unkown
HY-RS08538 Mmp2 Mouse Pre-designed siRNA Set A / Unkown
HY-RS08539 Mmp2 Rat Pre-designed siRNA Set A / Unkown
HY-W012856 3-Ethyltoluene / Unkown
HY-W095774 (E)-N-(3-Methoxyphenyl)cinnamamide Inhibitor / Unkown
HY-W277900 2-Methoxy-2,4-diphenylfuran-3-one / Unkown
HY-W750153 Propoxur-d7 / Unkown
HY-105854A Pipoxolan / Unkown
HY-113440R 5-Methoxytryptophol (Standard) / Unkown
HY-119110 LY52 Inhibitor / Unkown
HY-123130 ABT-770 Inhibitor / Unkown
HY-124341 ND-378 Inhibitor / Unkown
HY-128393S1 Trilinolein-13C54 / Unkown
HY-133845 CIL-102 / Unkown
HY-164525 SD-7300 Inhibitor / Unkown
HY-35513 3-Aminobenzene-1,2-diol Inhibitor 98.0% Unkown
HY-43586 BR351 precursor Inhibitor / Unkown
HY-B0689S1 Indinavir-13C4,15N / Unkown
HY-N13208 Stevia Powder / Unkown
HY-P3699A TNO003 TFA Substrate / Unkown
HY-P0273 Histatin 5 Inhibitor / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991609 ABX-MA1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MMP2 NCBI NCBI:4313