2. Gene
  3. Maoa - monoamine oxidase A Gene

Maoa - monoamine oxidase A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Mao

Gene ID: 29253 | Gene type: protein coding

About Maoa

Primary_assembly X: 6,030,795-6,099,593 reverse strand.mRatBN7.2:CM026994.1

This gene has 2 transcripts (splice variants), 147 orthologues, 10 paralogues and is associated with 26 phenotypes. Biased expression in Heart (RPKM 1152.5), Liver (RPKM 471.7) and 8 other tissues.

Summary

Enables flavin adenine dinucleotide binding activity; primary amine oxidase activity; and serotonin binding activity. Involved in phenylethylamine metabolic process and serotonin metabolic process. Located in mitochondrial outer membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease; Brunner Syndrome; alcohol use disorder; autism spectrum disorder; and panic disorder. Orthologous to human MAOA (Monoamine Oxidase A). [provided by Alliance of Genome Resources, Apr 2022]

Maoa Products(1)

mRNA Protein Name
NM_033653.1 NP_387502.1 amine oxidase [flavin-containing] A

Maoa Protein Structure

YobN

YobN: COG1231 (14 - 462)

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  • 526 a.a.
Protein Preferred Names Protein Names

amine oxidase [flavin-containing] A

MAO-A

monoamine oxidase type A

Related Agents

Approval
Bioactive Molecules (18)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14536 Methylene Blue Inhibitor 98.08% Unkown
HY-14280 Entacapone Inhibitor 99.92% Yes
HY-N0159 Paeonol 99.98% Unkown
HY-A0091A Pargyline Inhibitor 99.77% Unkown
HY-A0091 Pargyline hydrochloride Inhibitor 99.91% Unkown
HY-B0534 Moclobemide Inhibitor 99.90% Yes
HY-70057 Safinamide Inhibitor 99.89% Yes
HY-B1359 Methylene blue trihydrate Inhibitor ≥98.0% Yes
HY-70057A Safinamide mesylate Inhibitor 99.87% Yes
HY-14196 Toloxatone Inhibitor 99.84% Unkown
HY-B0884A Minaprine dihydrochloride Inhibitor 99.76% Unkown
HY-D0958 Methylene blue hydrate Inhibitor / Unkown
HY-B1558A Bifemelane hydrochloride Inhibitor 98.83% Unkown
HY-100679 Pirlindole Inhibitor ≥98.0% Unkown
HY-B0884 Minaprine Inhibitor / Unkown
HY-100679A Pirlindole mesylate Inhibitor / Unkown
HY-14280R Entacapone (Standard) Inhibitor / Unkown
HY-14280A Entacapone sodium salt Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-N0529 Rosmarinic acid 99.70% Phase 4
HY-100178 CX-157 Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (60)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14197A Clorgyline hydrochloride Inhibitor 99.70% Unkown
HY-W008566 Norharmane Inhibitor 99.46% Unkown
HY-19333 OG-L002 Inhibitor 99.81% Unkown
HY-110130 RN-1 dihydrochloride Inhibitor 99.75% Unkown
HY-16677A Mofegiline hydrochloride Inhibitor 99.57% Unkown
HY-131036 MAO-IN-M30 dihydrochloride Inhibitor 99.25% Unkown
HY-100588 VU0364770 Agonist 99.93% Unkown
HY-E70074 Monoamine oxidase, plasma / Unkown
HY-14201 Lazabemide Inhibitor 99.95% Unkown
HY-124591 TC-2153 Inhibitor 98.73% Unkown
HY-145259 HDAC6-IN-3 Inhibitor / Unkown
HY-156255 MAO-B-IN-25 Inhibitor 99.11% Unkown
HY-13339 Brofaromine Inhibitor 99.60% Unkown
HY-100027A Ro 41-1049 hydrochloride Inhibitor 99.96% Unkown
HY-14280S Entacapone-d10 Inhibitor ≥98.0% Unkown
HY-151466 HIF-1α-IN-5 Inhibitor / Unkown
HY-151596 MAO-A/5-HT2AR-IN-1 Inhibitor 99.71% Unkown
HY-W010130 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone Inhibitor 99.96% Unkown
HY-14260 RS 8359 Inhibitor 97.03% Unkown
HY-108048 Desoxypeganine Inhibitor / Unkown
HY-116097 PSB-1491 Inhibitor / Unkown
HY-119885A (±)-Amiflamine Inhibitor 99.23% Unkown
HY-120017 Befloxatone Inhibitor / Unkown
HY-121072 ASS234 Inhibitor / Unkown
HY-125515 Tetrahydroharmine Inhibitor / Unkown
HY-129449 AnnH31 Inhibitor 99.91% Unkown
HY-135265 Moclobemide N-Oxide Inhibitor / Unkown
HY-14202 Lazabemide hydrochloride Inhibitor / Unkown
HY-143438 2-PAT Inhibitor / Unkown
HY-143721 SSAO inhibitor-2 Inhibitor / Unkown
HY-144673 LSD1-IN-12 Inhibitor / Unkown
HY-144756 LSD1-IN-15 Inhibitor / Unkown
HY-144757 LSD1-IN-16 Inhibitor / Unkown
HY-144758 LSD1-IN-17 Inhibitor / Unkown
HY-149408 MAOA-IN-1 Inhibitor / Unkown
HY-149528 MAO-B-IN-24 Inhibitor / Unkown
HY-149978 LSD1-IN-26 / Unkown
HY-151094 FTEAA Inhibitor / Unkown
HY-151800 MAO-A/B-IN-2 Inhibitor / Unkown
HY-152109 AChE/MAO-IN-1 Inhibitor / Unkown
HY-152110 AChE/MAO-IN-2 Inhibitor / Unkown
HY-15386 Cimoxatone Inhibitor / Unkown
HY-154977 ETAP Inhibitor / Unkown
HY-157934 MAO-IN-4 Inhibitor / Unkown
HY-157981 AChE-IN-60 Inhibitor / Unkown
HY-157982 BChE-IN-28 Inhibitor / Unkown
HY-158092 ChEs/MAOs-IN-2 Inhibitor / Unkown
HY-161240 MAO-B-IN-30 Inhibitor / Unkown
HY-163322 MAO-A inhibitor 2 Inhibitor / Unkown
HY-70057S1 Safinamide-d4-1 Inhibitor / Unkown
HY-B0534S1 Moclobemide-d4 Inhibitor ≥99.0% Unkown
HY-D0004 Azure B Inhibitor 96.08% Unkown
HY-N12134 Methyl piperate Inhibitor / Unkown
HY-N12485 MAO-A inhibitor 1 Inhibitor / Unkown
HY-N1638 1-Methyl-2-undecyl-4(1H)-quinolone Inhibitor / Unkown
HY-RS08019 MAOA Human Pre-designed siRNA Set A / Unkown
HY-RS08020 Maoa Mouse Pre-designed siRNA Set A / Unkown
HY-RS08021 Maoa Rat Pre-designed siRNA Set A / Unkown
HY-134664 8α-(2-Methylacryloyloxy)-hirsutinolide-13-O-acetate Inhibitor / Unkown
HY-W792513 WAY-620147 Inhibitor ≥98.0% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Maoa NCBI NCBI:4128