MAOA - monoamine oxidase A Gene

Also Known as BRNRS; MAO-A

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 4128

About MAOA

Cytogenetic location: Xp11.3 Genomic coordinates (GRCh38): X:43,655,006-43,746,817 (from NCBI)

This gene has 10 transcripts (splice variants), 147 orthologues, 7 paralogues and is associated with 3 phenotypes. Broad expression in small intestine (RPKM 94.9), fat (RPKM 78.4) and 19 other tissues.

Summary

This gene is one of two neighboring gene family members that encode mitochondrial Enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of Other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

MAOA Products (2)

mRNA	Protein	Name
NM_000240.4	NP_000231.1	amine oxidase [flavin-containing] A isoform 1
NM_001270458.2	NP_001257387.1	amine oxidase [flavin-containing] A isoform 2

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	References	Source
enables monoamine oxidase activity	IDA IDA: Inferred from direct assay	20493079	GOA
enables primary methylamine oxidase activity	IDA IDA: Inferred from direct assay	20493079	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	28514442	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MAOA Protein Structure

Amino_oxidase

0
100
200
300
400
500
527 a.a.

Protein Preferred Names	Protein Names
amine oxidase [flavin-containing] A	monoamine oxidase type A

MAOA Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	MAOA	P21397	MAOB	Homo sapiens	P27338	Crosslink	30021884
Intra	MAOA	P21397	MAOB	Homo sapiens	P27338	Anti Tag CoIP	33961781
Intra	MAOA	P21397	MAOB	Homo sapiens	P27338	Anti Tag CoIP	28514442

Cross: Cross-species interaction Intra: Intraspecies interaction

MAOA Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P82291	Monoamine Oxidase A Antibody (YA2036)	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Dementia	Dementias Presenile Dementia Alzheimer Type Dementia Alzheimer Sclerosis Alzheimer Disease Dementia Alzheimer Dementia Primary Degenerative Alzheimer Type Dementia End Stage Alzheimer'S Dementia Alzheimer'S Type Atypical Dementia Alzheimer Type Presenile Dementia Early Onset Alzheimer Dementia Dementia In Alzheimer Disease Type 2 Dementia In Alzheimer Disease With Early Onset Early Onset Alzheimer Type Dementia, Uncomplicated Primary Degenerative Alzheimer Type Dementia, Early Onset Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated Alzheimer Disease Dementia With Early Onset Presenile Sclerosis Presenile Brain Sclerosis Presenile Alzheimer Brain Sclerosis Late Onset Alzheimer Dementia Dementia In Alzheimer Disease Type 1 Dementia In Alzheimer Disease With Late Onset Primary Degenerative Alzheimer Type Dementia, Late Onset Sdat - [Senile Dementia, Alzheimer Type] Alzheimer Disease Dementia With Late Onset Late Onset Alzheimer Brain Sclerosis Senile Alzheimer Brain Disease Senile Alzheimer Brain Sclerosis Senile Primary Degenerative Alzheimer Type Dementia Senile Dementia Of The Alzheimer Type Arteriosclerotic Dementia Strategic-Infarct Dementia Post Stroke Dementia Vascular Cognitive Impairment Vascular Dementia Dementia Of The Lewy Body Type Dementia With Lewy Bodies Sdlt - [Senile Dementia Of The Lewy Body Type] Senile Dementia Of The Lewy Body Type Alcohol-Related Dementia Alcoholic Dementia Nos Alcohol-Induced Dementia Alcoholic Brain Syndrome Chronic Alcoholic Brain Syndrome Alcohol Dementia Late Onset Alcoholic Psychosis Residual And Late-Onset Alcohol-Induced Psychotic Disorder Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder Late-Onset Psychoactive Substance-Induced Psychotic Disorder Inhalant Dementia Volatile Solvents Dementia Dementia In Paralysis Agitans Pdd - [Parkinson Disease Dementia] Dementia Syndrome Of Parkinson Disease Dementia In Parkinson Disease Parkinson Related Dementia Dementia In Huntington Chorea Hiv - [Human Immunodeficiency Virus] Dementia Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex Aids Related Dementia Dementia Due To Niacin Deficiency
Autism	Autistic Disorder Autism Susceptibility 1 Childhood Autism Autistic Disorder Of Childhood Onset Infantile Autism Kanner'S Syndrome Autistic
Antisocial Personality Disorder	Dissocial Personality Disorder Asocial Personality Psychopath.Personality Psychopathic Personality Psychopathic Personality Disorder Sociopathic Personality
Inhibited Male Orgasm	Male Orgasmic Disorder Psychosexual Dysfunction With Male Orgasmic Disorder
Anxiety	Anxiety Disorder Anxiety Disorders Anxiety State Anxieties Anxiety Neurosis
Paraphilia Disorder	Paraphilia Paraphilias
Conduct Disorder
Borderline Personality Disorder
Phobia, Specific	Specific Phobia Simple Phobia Phobia, Simple Isolated Phobia
Sexual Sadism	Sadism
Separation Anxiety Disorder	Separation Anxiety Disorder Of Childhood
Paranoid Schizophrenia	Chronic Paranoid Schizophrenia Paranoid Type Schizophrenia Paranoid Type Schizophrenia Subchronic State Paraphrenia - Late Paraphrenic Schizophrenia Schizophrenia, Paranoid
Migraine With Or Without Aura 1	Migraine Migraine With Or Without Aura, Susceptibility To, 1 Migraine Disorder Migraine Variant Migraines Migraine Disorders Mgr1 Mgau Ma Migraine With Or Without Aura Classic Migraine Common Migraine Disorder, Migraine Headache Migraine Headache Migrainous Migraine Headache Migraine Syndrome Headache Including Migraine Migraine, Susceptibility To
Impulse Control Disorder	Disruptive, Impulse Control, And Conduct Disorders
Alcoholic Neuropathy	Alcoholic Polyneuropathy Alcohol-Related Polyneuropathy Alcohol-Induced Polyneuropathy Alcoholic Peripheral Neuropathy
Melancholia
Narcissistic Personality Disorder
Heroin Dependence
Serotonin Syndrome	Serotonergic Syndrome Serotonin Storm Serotonin Toxicity Serotonin Toxidrome Malignant Carcinoid Syndrome
Obsessive-Compulsive Disorder	OCD Obsessive-Compulsive Disorder, Susceptibility To Anancastic Neurosis Obsessive Compulsive Disorder Anankastic Neurosis Obsessive-Compulsive Neurosis Obsessive Compulsive Behavior
Hypochondriasis	Hypochondriacal Disorder Hypochondria Hypochondriacal Neurosis Illness Anxiety Disorder Health Anxiety Disorder Hypochondriacal Reaction
Pheochromocytoma	Pheochromocytoma, Susceptibility To Phaeochromocytoma Adrenal Gland Chromaffin Paraganglioma Adrenal Gland Chromaffinoma Adrenal Gland Paraganglioma Adrenal Gland Pheochromocytoma Chromaffin Paraganglioma Of The Adrenal Gland Intraadrenal Paraganglioma PCC Chromaffin Cell Tumor Medullary Chromaffinoma Medullary Paraganglioma Pheochromoblastoma Pheochromocytomas Chromaffin Cell Neoplasm Pheochromocytoma, Malignant
Psychotic Disorder	Psychotic Disorders Mental Or Behavioural Disorder Psychotic Mental Disorders
Schizophrenia	SCZD Schizophrenia With Or Without An Affective Disorder Schizophrenia 12 Schizophrenia, Susceptibility To Schizophrenia-1 Dementia Praecox Schizophrenia 1
Oppositional Defiant Disorder	Disorder Oppositional Defiance Behavioural Disorder Oppositional Defiance Disruptive Mood Dysregulation Disorder
Pathological Gambling	Compulsive Gambling Gambling Gambling, Pathological Addiction Betting Addiction Gambling Betting Pathological Gambling Dependence
Brunner Syndrome	Monoamine Oxidase A Deficiency Antisocial Behavior BRNRS Deficiency Of Monoamine Oxidase A X-Linked Monoamine Oxidase Deficiency Susceptibility To Antisocial Behavior Antisocial Behavior, Susceptibility To Anti-Social Behavior
Barbiturate Abuse
Social Phobia	Phobia, Social Phobia Social Phobic Anxiety Disorder
Attention Deficit-Hyperactivity Disorder	Attention Deficit Hyperactivity Disorder ADHD Attention Deficit Disorder Attention Deficit-Hyperactivity Disorder, Susceptibility To Attention Deficit Disorder With Hyperactivity Hyperkinetic Disorder Hyperactivity Of Childhood Attention-Deficit/Hyperactivity Disorder Add Addh Attention Deficit Attention Deficit Disorder Of Childhood With Hyperactivity Attention Deficit Disorder With Hyperactivity Syndrome Hyperkinetic Syndrome Attention-Deficit Hyperactivity Disorder Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type Disturbance Of Activity And Attention Disorder Of Activity And Attention Adhd - [Attention Deficit Hyperactivity Disorder] Hyperkinetic Disorders Disorder Of Activity And Attention With Hyperkinesia Attention Deficit Syndrome With Hyperactivity
Major Depressive Disorder	Seasonal Affective Disorder Unipolar Depression Depression MDD Depressive Disorder Unipolar Depression, Susceptibility To Major Depressive Disorder 1 Major Depressive Disorder, Response To Citalopram Therapy In Major Depressive Disorder 2 Winter Depression Single Major Depressive Episode Sad Clinical Depression Major Depression Depressive Syndrome Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment Seasonal Affective Disorder, Susceptibility To Recurrent Major Depression Affective Disorder, Seasonal Depression In A Seasonal Pattern Depression Seasonal Major Depressive Disorder With A Seasonal Pattern Seasonal Depression Seasonal Mood Disorder Mental Depression Recurrent Major Depressive Episodes
Norrie Disease	Atrophia Bulborum Hereditaria Episkopi Blindness Pseudoglioma ND Norrie-Warburg Disease Anderson-Warburg Syndrome Fetal Iritis Syndrome Norrie Syndrome Norrie-Warburg Syndrome Ndp Congenital Progressive Oculo-Acoustico-Cerebral Degeneration Norrie'S Disease Oligophrenia Microphthalmus Pseudoglioma Congenita Whitnall-Norman Syndrome
Narcolepsy	Paroxysmal Sleep Gelineau Syndrome Narcoleptic Syndrome Narcolepsy-Cataplexy Syndrome Cataplexy And Narcolepsy Narcolepsy, Without Cataplexy Gelineau'S Syndrome Narcolepsy With Or Without Cataplexy Narcolepsy Nos
Fibromyalgia	Diffuse Myofascial Pain Syndrome Fibromyalgia Syndrome Fibromyalgia-Fibromyositis Syndrome Fibromyositis Fibrositis Fms Myofascial Pain Syndrome Myofascial Pain Syndromes
Anorexia Nervosa	Anorexia Nervosa, Susceptibility To ANON Anorexia Nervosa, Susceptibility To, 1 An Anorexia Nervosa 1 An - [Anorexia Nervosa]
Trichotillomania	TTM Hair-Pulling Syndrome Compulsive Hair Plucking Hair Pulling Disorder
Agoraphobia	Fear Of Open Spaces Phobia Of Going Out
Dysthymic Disorder	Dysthymia Chronic Depressive Disorder Chronic Depression Depressive Personality Depressive Personality Disorder Persistent Depressive Disorder Persistent Depression
Huntington Disease	Huntington'S Disease Huntington Chorea HD Huntington'S Chorea Huntington Chronic Progressive Hereditary Chorea Juvenile Huntington Disease Chronic Progressive Chorea Chronic Progressive Hereditary Chorea Hc - [Huntington Chorea] Hereditary Chorea Progressive Hereditary Chorea
Flying Phobia
Mood Disorder	Mood Disorders Episodic Mood Disorder
Mental Depression	Depression Depressive Disorder
Substance Dependence
Panic Disorder	Panic Anxiety Syndrome Panic Panic Disorder 1 Episodic Paroxysmal Anxiety Disorder
Personality Disorder	Personality Disorders Character Disorder Personality Specific Personality Disorders Enduring Personality Change After Psychiatric Illness
Body Mass Index Quantitative Trait Locus 11	OBESITY Obesity, Susceptibility To Leanness, Inherited Obesity, Susceptibility To, Bmiq11 Obesity, Mild, Early-Onset Obesity, Association With Obesity, Early-Onset, Susceptibility To Obesity, Severe Obesity, Severe, And Type Ii Diabetes Obesity, Late-Onset BMIQ11 Obesity Bmiq11 Obesity, Early-Onset Obesity , Susceptibility To Simple Obesity Nos Excess Fat Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified Adiposis
Parkinson Disease, Late-Onset	Parkinson Disease Parkinson'S Disease PD PARK Parkinson Disease, Susceptibility To Late Onset Parkinson'S Disease Late Onset Parkinson Disease Paralysis Agitans Primary Parkinsonism Idiopathic Parkinson Disease Parkinson'S Parkinson Disease, Late-Onset, Susceptibility To Parkinson Disease, Age Of Onset, Modifier Lewy Body Parkinson Disease Idiopathic Parkinson'S Disease Pd - [Parkinson Disease] Parkinson Disease Nos Parkinson, Nos Primary Parkinson Disease
Specific Developmental Disorder
Kleptomania	Pathological Stealing
Lesch-Nyhan Syndrome	Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency LNS Hprt Deficiency Complete Hypoxanthine-Guanine Phosphoribosyltransferase Deficiency Hypoxanthine Guanine Phosphoribosyltransferase Deficiency X-Linked Hyperuricemia Choreoathetosis Self-Mutilation Syndrome Hprt1 Deficiency Hprt Deficiency, Complete Deficiency Of Imp Pyrophosphorylase Hgprt Deficiency Lesch-Nyhan Disease Hypoxanthine Guanine Phosphoribosyltransferase 1 Deficiency Hg-Prt Deficiency Hypoxanthine-Guanine-Phosphoribosyltransferase Deficiency Lesch - Nyhan Syndrome Hprt1 Disorders Lesch Nyhan Syndrome Complete Hprt Deficiency Complete Lesch Nyhan Disease Complete Hprt Deficiency Deficiency Of Guanine Phosphoribosyltransferase Deficiency Of Hypoxanthine Phosphoribosyltransferase Hypoxanthine Phosphoribosyltransferase Deficiency Juvenile Gout, Choreoathetosis, Mental Retardation Syndrome Juvenile Hyperuricemia Syndrome Lnd Primary Hyperuricemia Syndrome Total Hprt Deficiency Total Hypoxanthine-Guanine Phosphoribosyl Transferase Deficiency X-Linked Primary Hyperuricemia X-Linked Uric Aciduria Enzyme Defect Hprt Complete Deficiency Hprt Deficiency Grade Iv Hypoxanthine Guanine Phosphoribosyltransferase Complete Deficiency Hypoxanthine Guanine Phosphoribosyltransferase Deficiency, Grade Iv Hypoxanthine-Guanine Phosphoribosyltransferase 1 Deficiency Hprt - [ Hypoxanthine-Guanine Phosphoribosyltransferase] Complete Deficiency Total Hgprt - [Hypoxanthine-Guanine Phosphoribosyltransferase] Deficiency
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Disease Of Mental Health	Mental Health Mental Disorders
Sexual Health Disorder	Sexual Health
Chronic Fatigue Syndrome	Myalgic Encephalomyelitis Postviral Fatigue Syndrome Cfs Myalgic Encephalitis Encephalomyelitis, Myalgic Chronic Fatigue Fatigue Syndrome, Chronic Benign Myalgic Encephalomyelitis Akureyri Akureyri Disease Cfs - [Chronic Fatigue Syndrome] Epidemic Neuromyasthenia Myalgic Encephalomyelitis Syndrome Me - [Myalgic Encephalomyelitis] Pvfs - [Postviral Fatigue Syndrome] Neuromyasthenia Iceland Disease Icelandic Disease
Pyromania	Firesetting Behavior Pathological Firesetting Pathological Fire-Setting
Pure Autonomic Failure	Orthostatic Hypotension Idiopathic Orthostatic Hypotension Postural Hypotension Bradbury-Eggleston Syndrome Bradbury Eggleston Syndrome Hypotension, Orthostatic Hypotension, Postural Paf Pure Dysautonomia Pure Idiopatic Dysautonomia Hypotension Orthostatic Primary Orthostatic Hypotension Chronic Orthostatic Hypotension
Atypical Depressive Disorder	Atypical Depression
Hepatic Encephalopathy	Encephalopathy, Hepatic Portal-Systemic Encephalopathy Hepatoencephalopathy He - [Hepatic Encephalopathy] Hepatic Encephalopathy Nos Hepatic Encephalopathy, Stage Unspecified Hepatic Coma Hepatocerebral Encephalopathy Hepatocerebral Intoxication
Severe Pre-Eclampsia	Severe Preeclampsia Antepartum Severe Pre-Eclampsia Postpartum Severe Pre-Eclampsia Severe Pre-Eclampsia, With Delivery Severe Toxemia Severe Pre-Eclampsia, Antepartum Condition Or Complication Severe Pre-Eclampsia, Postpartum Condition Or Complication Severe Puerperal Pre-Eclampsia Severe Pre-Eclamptic Toxaemia Severe Pet - [Pre-Eclamptic Toxaemia]
Phobic Disorder	Phobic Disorders Phobic Anxiety Disorder
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Postpartum Depression	Maternity Blues Postnatal Depression Depression, Postpartum Post-Partum Depression Depression Postpartum
Epilepsy	Epilepsy Syndrome Epileptic Syndrome Epilepsies Symptomatic Epilepsies Post Traumatic Epilepsy Traumatic Epilepsy Traumatic Epileptic Epilepsy Due To Hippocampal Sclerosis Epilepsy With Ammon'S Horn Sclerosis Epilepsy Due To Cortical Dysplasia Epilepsy Due To Neuronal Migration Disorders
Avoidant Personality Disorder	Anxious Personality Disorder Personality Disorders
Pick Disease Of Brain	Pick Disease Pick Disease Of The Brain Lobar Atrophy Of Brain Dementia With Lobar Atrophy And Neuronal Cytoplasmic Inclusions Pick'S Disease Behavioral Variant Of Frontotemporal Dementia Dementia In Pick'S Disease Lobar Atrophy Of The Brain Bvftd Bv-Ftd PIDB Picks Disease
Post-Traumatic Stress Disorder	PTSD Traumatic Neurosis Post Traumatic Stress Disorder Stress Disorders, Post-Traumatic Posttraumatic Stress Disorder Ptsd - [Post Traumatic Stress Disorder] Trauma-Related Disorders
Bipolar Disorder	Bipolar Depression Manic Disorder Depression, Bipolar Bipolar Disorder Manic Phase Depressive-Manic Psych. Manic Bipolar Affective Disorder Manic Bipolar I Disorder Manic Depression Manic Depressive Disorder Mixed Bipolar Disorder Bipolar Affective Disorder Bipolar Affective Psychosis Bipolar Spectrum Disorder Manic Depressive Illness Depression Bipolar Bipolar Disorder, Mixed Major Affective Disorder Major Affective Disorder 1 Major Affective Disorder 2
Voyeurism
Body Dysmorphic Disorder	Dysmorphophobia Body Dysmorphia Dysmorphic Syndrome Body Dysmorphic Disorders
Neurotic Disorder	Neurosis Reactive Depression Adjustment Disorders Neurotic Disorders Depressive Neurosis Neurotic Depression Neurotic Depression Reactive Type Neurotic Depressive State Psychoneurosis Depressive Disorder Depression, Neurotic
Tobacco Addiction	Nicotine Dependence Tobacco Addiction, Susceptibility To Nicotine Addiction Tobacco Use Disorder Smoking Habit Nicotine Dependence, Protection Against Nicotine Addiction, Protection From Cigarette Habituation Cigarette Habituation, Susceptibility To Smoking Habit, Susceptibility To Nicotine Dependence, Susceptibility To Nicotine Addiction, Susceptibility To Addiction, Tobacco, Susceptibility To Compulsive Tobacco User Syndrome Tobacco Dependence Tobacco Dependence Syndrome Cigarette Addiction Cigarette Dependence Smoking Addiction Smokers Syndrome
Sudden Infant Death Syndrome	SIDS Sudden Infant Death Syndrome, Susceptibility To Cot Death Crib Death Sudden Death Of Nonspecific Cause In Infancy Sudden Infant Death Death, Sudden, Syndrome, Infant
Generalized Anxiety Disorder	Anxiety Generalized
Short-Rib Thoracic Dysplasia 4 With Or Without Polydactyly	Asphyxiating Thoracic Dystrophy 4 SRTD4 Atd4 Jatd Jeune Asphyxiating Thoracic Dystrophy Jeune Syndrome 4
Restless Legs Syndrome	Wed Willis-Ekbom Disease Restless Leg Syndrome Ekbom Syndrome Wittmaack-Ekbom Syndrome Willis Ekbom Disease Ekbom'S Syndrome Rls Restless Legs Restless Legs Syndrome, Susceptibility To
Alcohol Dependence	Alcoholism Alcohol Dependence, Susceptibility To Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against Alcohol Dependence, Protection Against Alcoholism, Susceptibility To Alcoholic Intoxication, Chronic Pharyngeal Neoplasms Chronic Alcoholism Dipsomania Alcohol Addiction Ethanol Dependence Chronic Ethanolism Chronic Alcoholic Disease Nos Alcoholic Disease Nos Alcoholic
Non-Syndromic X-Linked Intellectual Disability 20	Mrx20
Fragile X Syndrome	FXS Martin-Bell Syndrome Fraxa Syndrome Marker X Syndrome X-Linked Mental Retardation And Macroorchidism Fragile X Mental Retardation Syndrome Fra Syndrome Mental Retardation, X-Linked, Associated With Marxq28 Frax Syndrome Symptomatic Form Of Fragile X Syndrome In Female Carriers Fragile-X Syndrome Fraxe Syndrome
Intermittent Explosive Disorder	Explosive Personality Disorder
Tic Disorder	Tics Behavioral Tic
Exhibitionism
Gilles De La Tourette Syndrome	Tourette Syndrome Tourette Disorder GTS Ts Gilles De La Tourette'S Syndrome Motor-Verbal Tic Disorder Guinon'S Disease Psychogenic Tics Tourette'S Syndrome Chronic Motor And Vocal Tic Disorder Td Tourette'S Disease Combined Vocal And Multiple Motor Tic Disorder [De La Tourette] Combined Vocal And Multiple Motor Tic Disorder Tic De La Tourette
Pedophilia	Paedophilia
Drug Dependence
Substance Abuse	Substance-Related Disorders Substance Abuse Problem
Autism Spectrum Disorder	Asd Autism Spectrum Disorders Autistic Continuum Pervasive Developmental Disorder Pervasive Development Disorder Autistic Behavior Autistic Disorder Autistic Autistic Disorder Of Childhood Onset Infantile Autism Childhood Autism Kanner Syndrome Pervasive Developmental Delay Nos Pervasive Developmental Disorder, Not Otherwise Specified
Alcohol Use Disorder	Alcohol Abuse Alcoholism Ethanol Abuse Alcohol Addiction Alcohol Dependence Alcoholic Intoxication, Chronic Alcohol-Related Disorders
Dependent Personality Disorder
Endogenous Depression	Clinical Depression Unipolar Depression Depressive Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (27)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-14536	Methylene Blue	Inhibitor	95.05%	Unkown
HY-14199	Selegiline hydrochloride	Inhibitor	99.96%	Unkown
HY-14280	Entacapone	Inhibitor	99.97%	Yes
HY-14197A	Clorgyline hydrochloride	Inhibitor	99.92%	Unkown
HY-N0159	Paeonol		99.98%	Unkown
HY-B1018A	Phenelzine sulfate	Inhibitor	99.96%	Unkown
HY-A0091A	Pargyline	Inhibitor	99.92%	Unkown
HY-70057	Safinamide	Inhibitor	99.86%	Yes
HY-A0091	Pargyline hydrochloride	Inhibitor	99.91%	Unkown
HY-B1359	Methylene blue trihydrate	Inhibitor	98.0%	Yes
HY-14197	Clorgyline	Inhibitor	99.76%	Unkown
HY-B0534	Moclobemide	Inhibitor	99.12%	Yes
HY-70057A	Safinamide mesylate	Inhibitor	99.07%	Yes
HY-14855B	Tedizolid phosphate	Inhibitor	99.61%	Yes
HY-D0958	Methylene blue hydrate	Inhibitor	/	Unkown
HY-B0678	Metaxalone		99.77%	Unkown
HY-N0159R	Paeonol (Standard)		99.98%	Unkown
HY-14196	Toloxatone	Inhibitor	98.11%	Unkown
HY-B1558A	Bifemelane hydrochloride	Inhibitor	99.86%	Unkown
HY-100679	Pirlindole	Inhibitor	98.90%	Unkown
HY-14895	Fabomotizole		99.96%	Unkown
HY-14198	Selegiline	Inhibitor	/	Unkown
HY-14280R	Entacapone (Standard)	Inhibitor	99.24%	Unkown
HY-100679A	Pirlindole mesylate	Inhibitor	/	Unkown
HY-B0678R	Metaxalone (Standard)		/	Unkown
HY-W018475	Rizatriptan	Agonist	/	Unkown
HY-14280A	Entacapone sodium salt	Inhibitor	/	Unkown

Clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Phase
HY-N0529	Rosmarinic acid		99.73%	Phase 4
HY-120017	Befloxatone	Inhibitor	/	Phase 3
HY-154977	ETAP	Inhibitor	/	Phase 3
HY-13339	Brofaromine	Inhibitor	99.60%	Phase 2
HY-14260	RS 8359	Inhibitor	97.35%	Phase 2
HY-129388	Pulrodemstat Methylbenzenesulfonate	Inhibitor	/	Phase 2
HY-100178	CX-157	Inhibitor	/	Phase 2
HY-108048	Desoxypeganine	Inhibitor	/	Phase 1

Pre-clinical Phase

Bioactive Molecules (134)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-W008566	Norharmane	Inhibitor	99.93%	Unkown
HY-129388B	Pulrodemstat benzenesulfonate	Inhibitor	99.64%	Unkown
HY-B1311	Proadifen hydrochloride		99.95%	Unkown
HY-Y1322	Triphenyl phosphate		99.67%	Unkown
HY-N2554	Osthenol		99.15%	Unkown
HY-N0126	Xanthone	Inhibitor	99.97%	Unkown
HY-W015490	1,4-Naphthoquinone	Inhibitor	99.97%	Unkown
HY-14536A	Methylene blue (purity≥70%)	Inhibitor	95.0%	Unkown
HY-110130	RN-1 dihydrochloride	Inhibitor	99.21%	Unkown
HY-E70074	Monoamine oxidase, plasma		/	Unkown
HY-N4177	Rubrofusarin gentiobioside	Inhibitor	99.07%	Unkown
HY-164099	LSD1/HDAC6-IN-2	Inhibitor	99.66%	Unkown
HY-19333	OG-L002	Inhibitor	99.55%	Unkown
HY-124591	TC-2153	Inhibitor	98.19%	Unkown
HY-N12485	MAO-A inhibitor 1	Inhibitor	98.55%	Unkown
HY-129388A	Pulrodemstat	Inhibitor	98.86%	Unkown
HY-16677A	Mofegiline hydrochloride	Inhibitor	99.57%	Unkown
HY-131036	MAO-IN-M30 dihydrochloride	Inhibitor	98.48%	Unkown
HY-14201	Lazabemide	Inhibitor	99.95%	Unkown
HY-D0004	Azure B	Inhibitor	99.87%	Unkown
HY-N4246	Bacopaside I		99.20%	Unkown
HY-100588	VU0364770	Agonist	99.94%	Unkown
HY-137570	Ethyl homovanillate	Inhibitor	98.41%	Unkown
HY-149213	LSD1/TLK1-IN-1		99.20%	Unkown
HY-W004882	6-Hydroxy-1-tetralone		99.56%	Unkown
HY-W655727	(-)-2-Phenylpropylamine	Inhibitor	98.44%	Unkown
HY-125515	Tetrahydroharmine	Inhibitor	99.61%	Unkown
HY-100027A	Ro 41-1049 hydrochloride	Inhibitor	99.57%	Unkown
HY-121072	ASS234	Inhibitor	99.6%	Unkown
HY-145259	HDAC6-IN-3	Inhibitor	98.0%	Unkown
HY-149408	MAOA-IN-1	Inhibitor	98.24%	Unkown
HY-151466	HIF-1α-IN-5	Inhibitor	99.95%	Unkown
HY-N0126R	Xanthone (Standard)	Inhibitor	99.99%	Unkown
HY-W015490S	1,4-Naphthoquinone-d6	Inhibitor	99.20%	Unkown
HY-W049881	9-Methyl-β-carboline		99.86%	Unkown
HY-100588A	VU0364770 hydrochloride	Agonist	99.63%	Unkown
HY-101578	2614W94	Inhibitor	99.76%	Unkown
HY-114620	MAO-B-IN-55	Inhibitor	98.10%	Unkown
HY-14280S	Entacapone-d10	Inhibitor	98.6%	Unkown
HY-151596	MAO-A/5-HT2AR-IN-1	Inhibitor	99.71%	Unkown
HY-156255	MAO-B-IN-25	Inhibitor	99.11%	Unkown
HY-70057S1	Safinamide-d4-1	Inhibitor	98.90%	Unkown
HY-B1018AS	Phenelzine-d5 sulfate	Inhibitor	99.97%	Unkown
HY-W010130	7-Hydroxy-3,4-dihydro-2(1H)-quinolinone	Inhibitor	99.96%	Unkown
HY-W275048	MAO-A inhibitor 3	Inhibitor	99.85%	Unkown
HY-Y1322S	Triphenyl phosphate-d15		99.74%	Unkown
HY-100027	Ro 41-1049	Inhibitor	/	Unkown
HY-100679B	(R)-Pirlindole mesylate	Inhibitor	/	Unkown
HY-106041A	Sercloremine hydrochloride	Inhibitor	/	Unkown
HY-106972	SL-251131	Inhibitor	/	Unkown
HY-108048A	Desoxypeganine hydrochloride	Inhibitor	/	Unkown
HY-114915	PSB-1434	Inhibitor	98.05%	Unkown
HY-116097	PSB-1491	Inhibitor	/	Unkown
HY-119885A	(±)-Amiflamine	Inhibitor	99.23%	Unkown
HY-129388C	Pulrodemstat hydrochloride	Inhibitor	/	Unkown
HY-129449	AnnH31	Inhibitor	99.91%	Unkown
HY-131660	MAO-B-IN-54	Inhibitor	/	Unkown
HY-134664	8α-(2-Methylacryloyloxy)-hirsutinolide-13-O-acetate	Inhibitor	/	Unkown
HY-135265	Moclobemide N-Oxide	Inhibitor	99.35%	Unkown
HY-136878	LSD1-IN-10	Inhibitor	/	Unkown
HY-14198B	(±)-Selegiline hydrochloride	Inhibitor	/	Unkown
HY-14202	Lazabemide hydrochloride	Inhibitor	95.0%	Unkown
HY-143438	2-PAT	Inhibitor	/	Unkown
HY-144673	LSD1-IN-12	Inhibitor	/	Unkown
HY-144756	LSD1-IN-15	Inhibitor	/	Unkown
HY-144757	LSD1-IN-16	Inhibitor	/	Unkown
HY-144758	LSD1-IN-17	Inhibitor	/	Unkown
HY-149528	MAO-B-IN-24	Inhibitor	/	Unkown
HY-149978	LSD1-IN-26		/	Unkown
HY-151094	FTEAA	Inhibitor	/	Unkown
HY-151800	MAO-A/B-IN-2	Inhibitor	/	Unkown
HY-152109	AChE/MAO-IN-1	Inhibitor	/	Unkown
HY-152110	AChE/MAO-IN-2	Inhibitor	/	Unkown
HY-15386	Cimoxatone	Inhibitor	98.03%	Unkown
HY-157934	MAO-IN-4	Inhibitor	/	Unkown
HY-157981	AChE-IN-60	Inhibitor	/	Unkown
HY-157982	BChE-IN-28	Inhibitor	/	Unkown
HY-158092	ChEs/MAOs-IN-2	Inhibitor	/	Unkown
HY-158732	MAO-B-IN-33	Inhibitor	/	Unkown
HY-159106	MeSeI		/	Unkown
HY-161240	MAO-B-IN-30	Inhibitor	98.53%	Unkown
HY-162606	MAO-A/B-IN-3	Inhibitor	/	Unkown
HY-162760	COMT-IN-1	Inhibitor	/	Unkown
HY-163322	MAO-A inhibitor 2	Inhibitor	/	Unkown
HY-163618	DHMQ		/	Unkown
HY-170487	MAO-B-IN-38	Inhibitor	/	Unkown
HY-174833	MAO-A-IN-2	Inhibitor	/	Unkown
HY-174834	MAO-B-IN-44	Inhibitor	/	Unkown
HY-176254	LSD1-IN-43	Inhibitor	/	Unkown
HY-176271	MAO-B-IN-45		/	Unkown
HY-178149	MAO-A/B-IN-5	Inhibitor	/	Unkown
HY-178352	MAO-B-IN-49		/	Unkown
HY-179126	BChE/MAO-A-IN-1	Inhibitor	/	Unkown
HY-180552	AChE-IN-104	Inhibitor	/	Unkown
HY-180783	AChE/BChE/MAO-A-IN-1	Inhibitor	/	Unkown
HY-180843	Aβ/tau aggregation-IN-4	Inhibitor	/	Unkown
HY-181110	MAO-A-IN-4	Inhibitor	/	Unkown
HY-182727	MDL 72392	Inhibitor	/	Unkown
HY-184159	AChE/BChE/MAO-A-IN-2	Inhibitor	/	Unkown
HY-184381	MAO-B-IN-61	Inhibitor	/	Unkown
HY-186195	Methyl-cudratricusxanthone B		/	Unkown
HY-B0534S	Moclobemide-d8	Inhibitor	/	Unkown
HY-B0534S1	Moclobemide-d4	Inhibitor	99.0%	Unkown
HY-B0678S	Metaxalone-d3		98.0%	Unkown
HY-B0678S1	Metaxalone-d6		/	Unkown
HY-D3221	MAO Probe 1		/	Unkown
HY-N0377B	(R)-Liquiritigenin	Inhibitor	/	Unkown
HY-N1638	1-Methyl-2-undecyl-4(1H)-quinolone	Inhibitor	/	Unkown
HY-N18471	5,7-Dihydroxytryptamine	Ligand	/	Unkown
HY-N18471A	5,7-Dihydroxytryptamine hydrobromide	Ligand	/	Unkown
HY-N18471B	5,7-Dihydroxytryptamine creatinine sulfate	Ligand	/	Unkown
HY-RS08019	MAOA Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08020	Maoa Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08021	Maoa Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W008566S	Norharmane-13C		/	Unkown
HY-W1058437	(trans)-m-CI-PCA hydrochloride	Inhibitor	/	Unkown
HY-100679S	Pirlindole-d4	Inhibitor	/	Unkown
HY-105041	Tedizolid phosphate sodium	Inhibitor	/	Unkown
HY-105127	Brofaromine hydrochloride	Inhibitor	/	Unkown
HY-124331	H77-77	Inhibitor	/	Unkown
HY-124885	MD 220661	Inhibitor	/	Unkown
HY-14198S	Selegiline-d5	Inhibitor	/	Unkown
HY-14199S	Selegiline-d5 hydrochloride	Inhibitor	/	Unkown
HY-160936	5-Hydroxyindoleacetaldehyde		/	Unkown
HY-167152	Pirlindole lactate	Inhibitor	/	Unkown
HY-19333A	OG-L002 hydrochloride	Inhibitor	/	Unkown
HY-70057S4	Safinamide-d5	Inhibitor	/	Unkown
HY-N12134	Methyl piperate	Inhibitor	/	Unkown
HY-N13041	Acacetin 7-O-(6-O-malonylglucoside)	Inhibitor	/	Unkown
HY-W029600	6,7-Dimethylisatin	Inhibitor	/	Unkown
HY-W067583	Norharmine	Inhibitor	/	Unkown
HY-W279140	Pirlindole hydrochloride	Inhibitor	/	Unkown
HY-W700241	Norharman-d7	Inhibitor	/	Unkown
HY-W792513	WAY-620147	Inhibitor	98.0%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	MAOA	VGNC	VGNC:42953
Mus musculus	MAOA	MGD	MGI:96915
Felis catus	MAOA	VGNC	VGNC:68149
Rattus norvegicus	MAOA	RGD	RGD:61898
Bos taurus	MAOA	VGNC	VGNC:31174
Macaca mulatta	MAOA	VGNC	VGNC:74487
Others	MAOA	NCBI