MAOB - monoamine oxidase B Gene

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 4129

About MAOB

Cytogenetic location: Xp11.3 Genomic coordinates (GRCh38): X:43,766,610-43,882,450 (from NCBI)

This gene has 3 transcripts (splice variants), 333 orthologues and 7 paralogues. Broad expression in liver (RPKM 72.6), ovary (RPKM 62.8) and 18 other tissues.

Summary

The protein encoded by this gene belongs to the flavin Monoamine Oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008]

MAOB Products (2)

mRNA	Protein	Name
XM_017029524.3	XP_016885013.1	amine oxidase [flavin-containing] B isoform X1
NM_000898.5	NP_000889.3	amine oxidase [flavin-containing] B

MAOB Protein Structure

Amino_oxidase

0
100
200
300
400
520 a.a.

Protein Preferred Names	Protein Names
amine oxidase [flavin-containing] B	MAO, brain MAO, platelet MAO-B adrenalin oxidase monoamine oxidase type B tyramine oxidase

MAOB Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	MAOB	P27338	FGF14	Homo sapiens	Q92915-2	Validated Y2H	32296183
Intra	MAOB	P27338	FGF14	Homo sapiens	Q92915-2	Y2H Array	32296183
Intra	MAOB	P27338	FGF14	Homo sapiens	Q92915-2	Y2H Prey Pooling	32296183
Intra	MAOB	P27338	RHBDD2	Homo sapiens	Q6NTF9-3	Y2H Array	32296183
Intra	MAOB	P27338	RHBDD2	Homo sapiens	Q6NTF9-3	Validated Y2H	32296183
Intra	MAOB	P27338	RHBDD2	Homo sapiens	Q6NTF9-3	Y2H Prey Pooling	32296183
Intra	MAOB	P27338	GLE1	Homo sapiens	Q53GS7	Y2H Pooling	32814053
Intra	MAOB	P27338	GLE1	Homo sapiens	Q53GS7	Validated Y2H	32814053
Intra	MAOB	P27338	GLE1	Homo sapiens	Q53GS7	Y2H Array	32814053
Intra	MAOB	P27338	LAMP2	Homo sapiens	P13473-2	Validated Y2H	32814053
Intra	MAOB	P27338	LAMP2	Homo sapiens	P13473-2	Y2H Array	32814053
Intra	MAOB	P27338	LAMP2	Homo sapiens	P13473-2	Y2H Pooling	32814053
Intra	MAOB	P27338	CHAT	Homo sapiens	P28329-3	Y2H Pooling	32814053
Intra	MAOB	P27338	CHAT	Homo sapiens	P28329-3	Validated Y2H	32814053
Intra	MAOB	P27338	CHAT	Homo sapiens	P28329-3	Y2H Array	32814053
Intra	MAOB	P27338	q9y649_human	Homo sapiens	Q9Y649	Validated Y2H	32814053
Intra	MAOB	P27338	q9y649_human	Homo sapiens	Q9Y649	Y2H Pooling	32814053
Intra	MAOB	P27338	q9y649_human	Homo sapiens	Q9Y649	Y2H Array	32814053
Intra	MAOB	P27338	SH3GLB1	Homo sapiens	Q9Y371	Validated Y2H	32814053
Intra	MAOB	P27338	SH3GLB1	Homo sapiens	Q9Y371	Y2H Pooling	32814053
Intra	MAOB	P27338	SH3GLB1	Homo sapiens	Q9Y371	Y2H Array	32814053
Intra	MAOB	P27338	NUP58	Homo sapiens	Q9BVL2	Validated Y2H	32814053
Intra	MAOB	P27338	NUP58	Homo sapiens	Q9BVL2	Y2H Array	32814053
Intra	MAOB	P27338	NUP58	Homo sapiens	Q9BVL2	Y2H Pooling	32814053
Intra	MAOB	P27338	COX20	Homo sapiens	Q5RI15	Validated Y2H	32296183
Intra	MAOB	P27338	COX20	Homo sapiens	Q5RI15	Y2H Array	32296183
Intra	MAOB	P27338	COX20	Homo sapiens	Q5RI15	Y2H Prey Pooling	32296183
Intra	MAOB	P27338	RAN	Homo sapiens	P62826	Validated Y2H	32814053
Intra	MAOB	P27338	RAN	Homo sapiens	P62826	Y2H Pooling	32814053
Intra	MAOB	P27338	RAN	Homo sapiens	P62826	Y2H Array	32814053
Intra	MAOB	P27338	FGFR3	Homo sapiens	P22607	Validated Y2H	32814053
Intra	MAOB	P27338	FGFR3	Homo sapiens	P22607	Y2H Array	32814053
Intra	MAOB	P27338	FGFR3	Homo sapiens	P22607	Y2H Pooling	32814053
Intra	MAOB	P27338	HRAS	Homo sapiens	P01112	Validated Y2H	32814053
Intra	MAOB	P27338	HRAS	Homo sapiens	P01112	Y2H Array	32814053
Intra	MAOB	P27338	HRAS	Homo sapiens	P01112	Y2H Pooling	32814053
Intra	MAOB	P27338	GSN	Homo sapiens	P06396	Validated Y2H	32814053
Intra	MAOB	P27338	GSN	Homo sapiens	P06396	Y2H Pooling	32814053
Intra	MAOB	P27338	GSN	Homo sapiens	P06396	Y2H Array	32814053
Intra	MAOB	P27338	SPRED1	Homo sapiens	Q7Z699	Validated Y2H	32814053
Intra	MAOB	P27338	SPRED1	Homo sapiens	Q7Z699	Y2H Array	32814053
Intra	MAOB	P27338	SPRED1	Homo sapiens	Q7Z699	Y2H Pooling	32814053
Intra	MAOB	P27338	PRPF40A	Homo sapiens	O75400-2	Y2H Pooling	32814053
Intra	MAOB	P27338	PRPF40A	Homo sapiens	O75400-2	Validated Y2H	32814053
Intra	MAOB	P27338	PRPF40A	Homo sapiens	O75400-2	Y2H Array	32814053
Intra	MAOB	P27338	CASP6	Homo sapiens	P55212	Validated Y2H	32814053
Intra	MAOB	P27338	CASP6	Homo sapiens	P55212	Y2H Array	32814053
Intra	MAOB	P27338	CASP6	Homo sapiens	P55212	Y2H Pooling	32814053
Intra	MAOB	P27338	UBQLN1	Homo sapiens	Q9UMX0	Validated Y2H	32814053
Intra	MAOB	P27338	UBQLN1	Homo sapiens	Q9UMX0	Y2H Array	32814053
Intra	MAOB	P27338	UBQLN1	Homo sapiens	Q9UMX0	Y2H Pooling	32814053
Intra	MAOB	P27338	COQ8A	Homo sapiens	Q8NI60	Validated Y2H	32814053
Intra	MAOB	P27338	COQ8A	Homo sapiens	Q8NI60	Y2H Array	32814053
Intra	MAOB	P27338	COQ8A	Homo sapiens	Q8NI60	Y2H Pooling	32814053

Cross: Cross-species interaction Intra: Intraspecies interaction

MAOB Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P82294	Monoamine Oxidase B Antibody (YA2039)	WB, IHC-P	Human

Related Diseases

Diseases	Alias
Pheochromocytoma	Pheochromocytoma, Susceptibility To Phaeochromocytoma Adrenal Gland Chromaffin Paraganglioma Adrenal Gland Chromaffinoma Adrenal Gland Paraganglioma Adrenal Gland Pheochromocytoma Chromaffin Paraganglioma Of The Adrenal Gland Intraadrenal Paraganglioma PCC Chromaffin Cell Tumor Medullary Chromaffinoma Medullary Paraganglioma Pheochromoblastoma Pheochromocytomas Chromaffin Cell Neoplasm Pheochromocytoma, Malignant
Huntington Disease	Huntington'S Disease Huntington Chorea HD Huntington'S Chorea Huntington Chronic Progressive Hereditary Chorea Juvenile Huntington Disease Chronic Progressive Chorea Chronic Progressive Hereditary Chorea Hc - [Huntington Chorea] Hereditary Chorea Progressive Hereditary Chorea
Antisocial Personality Disorder	Dissocial Personality Disorder Asocial Personality Psychopath.Personality Psychopathic Personality Psychopathic Personality Disorder Sociopathic Personality
Autism Spectrum Disorder	Asd Autism Spectrum Disorders Autistic Continuum Pervasive Developmental Disorder Pervasive Development Disorder Autistic Behavior Autistic Disorder Autistic Autistic Disorder Of Childhood Onset Infantile Autism Childhood Autism Kanner Syndrome Pervasive Developmental Delay Nos Pervasive Developmental Disorder, Not Otherwise Specified
Dementia, Lewy Body	Lewy Body Dementia Lewy Body Disease Diffuse Lewy Body Disease Dementia With Lewy Bodies DLB Autosomal Dominant Diffuse Lewy Body Disease Cortical Lewy Body Disease Dementia, Lewy Body, Susceptibility To Lewy Body Dementia, Susceptibility To Senile Dementia Of The Lewy Body Type Dementia Of The Lewy Body Type Lbd Diffuse Lewy Body Disease With Gaze Palsy Dysphasic Dementia Hereditary Lewy Body Type Senile Dementia Lewy Body Variant Of Alzheimer Disease Lewy Bodies Lewy Body Dlbd - [Diffuse Lewy Body Disease] Clbd - [Cortical Lewy Body Disease]
Dementia	Dementias Presenile Dementia Alzheimer Type Dementia Alzheimer Sclerosis Alzheimer Disease Dementia Alzheimer Dementia Primary Degenerative Alzheimer Type Dementia End Stage Alzheimer'S Dementia Alzheimer'S Type Atypical Dementia Alzheimer Type Presenile Dementia Early Onset Alzheimer Dementia Dementia In Alzheimer Disease Type 2 Dementia In Alzheimer Disease With Early Onset Early Onset Alzheimer Type Dementia, Uncomplicated Primary Degenerative Alzheimer Type Dementia, Early Onset Primary Degenerative Alzheimer Type Dementia, Presenile Onset, Uncomplicated Alzheimer Disease Dementia With Early Onset Presenile Sclerosis Presenile Brain Sclerosis Presenile Alzheimer Brain Sclerosis Late Onset Alzheimer Dementia Dementia In Alzheimer Disease Type 1 Dementia In Alzheimer Disease With Late Onset Primary Degenerative Alzheimer Type Dementia, Late Onset Sdat - [Senile Dementia, Alzheimer Type] Alzheimer Disease Dementia With Late Onset Late Onset Alzheimer Brain Sclerosis Senile Alzheimer Brain Disease Senile Alzheimer Brain Sclerosis Senile Primary Degenerative Alzheimer Type Dementia Senile Dementia Of The Alzheimer Type Arteriosclerotic Dementia Strategic-Infarct Dementia Post Stroke Dementia Vascular Cognitive Impairment Vascular Dementia Dementia Of The Lewy Body Type Dementia With Lewy Bodies Sdlt - [Senile Dementia Of The Lewy Body Type] Senile Dementia Of The Lewy Body Type Alcohol-Related Dementia Alcoholic Dementia Nos Alcohol-Induced Dementia Alcoholic Brain Syndrome Chronic Alcoholic Brain Syndrome Alcohol Dementia Late Onset Alcoholic Psychosis Residual And Late-Onset Alcohol-Induced Psychotic Disorder Mental And Behavioural Disorders Due To Use Of Sedatives Or Hypnotics, Residual And Late-Onset Psychotic Disorder Late-Onset Psychoactive Substance-Induced Psychotic Disorder Inhalant Dementia Volatile Solvents Dementia Dementia In Paralysis Agitans Pdd - [Parkinson Disease Dementia] Dementia Syndrome Of Parkinson Disease Dementia In Parkinson Disease Parkinson Related Dementia Dementia In Huntington Chorea Hiv - [Human Immunodeficiency Virus] Dementia Hiv- [Human Immunodeficiency Virus] Associated Cognitive Motor Complex Hiv- [Human Immunodeficiency Virus] Associated Dementia Complex Aids - [Acquired Immunodeficiency Syndrome] Dementia Complex Aids Related Dementia Dementia Due To Niacin Deficiency
Autism	Autistic Disorder Autism Susceptibility 1 Childhood Autism Autistic Disorder Of Childhood Onset Infantile Autism Kanner'S Syndrome Autistic
Asperger Syndrome	Asperger Disorder
Anxiety	Anxiety Disorder Anxiety Disorders Anxiety State Anxieties Anxiety Neurosis
Vascular Dementia	Dementia, Vascular Multi Infarct Dementia Multifocal Dementia Dementia Vascular Vascular Dementia, Susceptibility To Dementia, Multi-Infarct Multi-Infarct Dementia
Migraine With Or Without Aura 1	Migraine Migraine With Or Without Aura, Susceptibility To, 1 Migraine Disorder Migraine Variant Migraines Migraine Disorders Mgr1 Mgau Ma Migraine With Or Without Aura Classic Migraine Common Migraine Disorder, Migraine Headache Migraine Headache Migrainous Migraine Headache Migraine Syndrome Headache Including Migraine Migraine, Susceptibility To
Impulse Control Disorder	Disruptive, Impulse Control, And Conduct Disorders
Pure Autonomic Failure	Orthostatic Hypotension Idiopathic Orthostatic Hypotension Postural Hypotension Bradbury-Eggleston Syndrome Bradbury Eggleston Syndrome Hypotension, Orthostatic Hypotension, Postural Paf Pure Dysautonomia Pure Idiopatic Dysautonomia Hypotension Orthostatic Primary Orthostatic Hypotension Chronic Orthostatic Hypotension
Rem Sleep Behavior Disorder	Rem Sleep Behaviour Disorder Rapid Eye Movement Sleep Behavior Disorder Rapid Eye Movement Sleep Behaviour Disorder Rem - [Rapid Eye Movement] Behaviour Disorder
Serotonin Syndrome	Serotonergic Syndrome Serotonin Storm Serotonin Toxicity Serotonin Toxidrome Malignant Carcinoid Syndrome
Obsessive-Compulsive Disorder	OCD Obsessive-Compulsive Disorder, Susceptibility To Anancastic Neurosis Obsessive Compulsive Disorder Anankastic Neurosis Obsessive-Compulsive Neurosis Obsessive Compulsive Behavior
Pick Disease Of Brain	Pick Disease Pick Disease Of The Brain Lobar Atrophy Of Brain Dementia With Lobar Atrophy And Neuronal Cytoplasmic Inclusions Pick'S Disease Behavioral Variant Of Frontotemporal Dementia Dementia In Pick'S Disease Lobar Atrophy Of The Brain Bvftd Bv-Ftd PIDB Picks Disease
Major Depressive Disorder	Seasonal Affective Disorder Unipolar Depression Depression MDD Depressive Disorder Unipolar Depression, Susceptibility To Major Depressive Disorder 1 Major Depressive Disorder, Response To Citalopram Therapy In Major Depressive Disorder 2 Winter Depression Single Major Depressive Episode Sad Clinical Depression Major Depression Depressive Syndrome Major Depressive Disorder And Accelerated Response To Antidepressant Drug Treatment Seasonal Affective Disorder, Susceptibility To Recurrent Major Depression Affective Disorder, Seasonal Depression In A Seasonal Pattern Depression Seasonal Major Depressive Disorder With A Seasonal Pattern Seasonal Depression Seasonal Mood Disorder Mental Depression Recurrent Major Depressive Episodes
Norrie Disease	Atrophia Bulborum Hereditaria Episkopi Blindness Pseudoglioma ND Norrie-Warburg Disease Anderson-Warburg Syndrome Fetal Iritis Syndrome Norrie Syndrome Norrie-Warburg Syndrome Ndp Congenital Progressive Oculo-Acoustico-Cerebral Degeneration Norrie'S Disease Oligophrenia Microphthalmus Pseudoglioma Congenita Whitnall-Norman Syndrome
Psychotic Disorder	Psychotic Disorders Mental Or Behavioural Disorder Psychotic Mental Disorders
Dystonia	Dystonic Disease Dystonic Disorder Dystonia Disorders Neuroleptic Dyskinesia
Pathological Gambling	Compulsive Gambling Gambling Gambling, Pathological Addiction Betting Addiction Gambling Betting Pathological Gambling Dependence
Brunner Syndrome	Monoamine Oxidase A Deficiency Antisocial Behavior BRNRS Deficiency Of Monoamine Oxidase A X-Linked Monoamine Oxidase Deficiency Susceptibility To Antisocial Behavior Antisocial Behavior, Susceptibility To Anti-Social Behavior
Postencephalitic Parkinson Disease	Postencephalitic Parkinsonism Parkinson Disease, Postencephalitic
Barbiturate Abuse
Interval Angle-Closure Glaucoma	Intermittent Angle-Closure Glaucoma Angle-Closure Glaucoma, Subacute Prodromal Angle Closure Glaucoma
Vascular Parkinsonism
Attention Deficit-Hyperactivity Disorder	Attention Deficit Hyperactivity Disorder ADHD Attention Deficit Disorder Attention Deficit-Hyperactivity Disorder, Susceptibility To Attention Deficit Disorder With Hyperactivity Hyperkinetic Disorder Hyperactivity Of Childhood Attention-Deficit/Hyperactivity Disorder Add Addh Attention Deficit Attention Deficit Disorder Of Childhood With Hyperactivity Attention Deficit Disorder With Hyperactivity Syndrome Hyperkinetic Syndrome Attention-Deficit Hyperactivity Disorder Attention-Deficit/Hyperactivity Disorder, Predominantly Inattentive Type Disturbance Of Activity And Attention Disorder Of Activity And Attention Adhd - [Attention Deficit Hyperactivity Disorder] Hyperkinetic Disorders Disorder Of Activity And Attention With Hyperkinesia Attention Deficit Syndrome With Hyperactivity
Body Mass Index Quantitative Trait Locus 11	OBESITY Obesity, Susceptibility To Leanness, Inherited Obesity, Susceptibility To, Bmiq11 Obesity, Mild, Early-Onset Obesity, Association With Obesity, Early-Onset, Susceptibility To Obesity, Severe Obesity, Severe, And Type Ii Diabetes Obesity, Late-Onset BMIQ11 Obesity Bmiq11 Obesity, Early-Onset Obesity , Susceptibility To Simple Obesity Nos Excess Fat Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified Adiposis
Mood Disorder	Mood Disorders Episodic Mood Disorder
Supranuclear Palsy, Progressive, 1	Progressive Supranuclear Palsy Steele-Richardson-Olszewski Syndrome Supranuclear Palsy, Progressive Psp Progressive Supranuclear Ophthalmoplegia PSNP1 Familial Progressive Supranuclear Palsy Richardson'S Syndrome Psp Syndrome Progressive Supranuclear Palsy 1 Supranuclear Palsy Progressive Ophthalmoplegia, Supranuclear, Progressive Steele-Richardson-Olszewksi Syndrome
Personality Disorder	Personality Disorders Character Disorder Personality Specific Personality Disorders Enduring Personality Change After Psychiatric Illness
Parkinson Disease, Late-Onset	Parkinson Disease Parkinson'S Disease PD PARK Parkinson Disease, Susceptibility To Late Onset Parkinson'S Disease Late Onset Parkinson Disease Paralysis Agitans Primary Parkinsonism Idiopathic Parkinson Disease Parkinson'S Parkinson Disease, Late-Onset, Susceptibility To Parkinson Disease, Age Of Onset, Modifier Lewy Body Parkinson Disease Idiopathic Parkinson'S Disease Pd - [Parkinson Disease] Parkinson Disease Nos Parkinson, Nos Primary Parkinson Disease
Atypical Depressive Disorder	Atypical Depression
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder
Constipation
Amyotrophic Lateral Sclerosis 1	Amyotrophic Lateral Sclerosis ALS Lou Gehrig Disease Amyotrophic Lateral Sclerosis Type 1 Charcot Disease ALS1 Amyotrophic Lateral Sclerosis, Susceptibility To Fals Lou Gehrig'S Disease Mnd Motor Neuron Disease Familial Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis 1, Familial Amyotrophic Lateral Sclerosis 1, Autosomal Dominant Motor Neuron Disease, Bulbar Motor Neurone Disease Amyotrophic Lateral Sclerosis With Dementia Dementia With Amyotrophic Lateral Sclerosis Motor Neuron Disease, Amyotrophic Lateral Sclerosis Sclerosis, Lateral, Amyotrophic Sclerosis, Lateral, Amyotrophic, Type 1 Amyotrophic Sclerosis Als - [Amyotrophic Lateral Sclerosis] Wasting Palsy Amyotrophic Paralysis Amyotrophy Lateral Sclerosis Wasting Paralysis Spinal Progressive Amyotrophy Progressive Atrophic Paralysis
Epilepsy	Epilepsy Syndrome Epileptic Syndrome Epilepsies Symptomatic Epilepsies Post Traumatic Epilepsy Traumatic Epilepsy Traumatic Epileptic Epilepsy Due To Hippocampal Sclerosis Epilepsy With Ammon'S Horn Sclerosis Epilepsy Due To Cortical Dysplasia Epilepsy Due To Neuronal Migration Disorders
Post-Traumatic Stress Disorder	PTSD Traumatic Neurosis Post Traumatic Stress Disorder Stress Disorders, Post-Traumatic Posttraumatic Stress Disorder Ptsd - [Post Traumatic Stress Disorder] Trauma-Related Disorders
Sleep Disorder	Sleep Disorders Non-Organic Sleep Disorder
Hepatic Encephalopathy	Encephalopathy, Hepatic Portal-Systemic Encephalopathy Hepatoencephalopathy He - [Hepatic Encephalopathy] Hepatic Encephalopathy Nos Hepatic Encephalopathy, Stage Unspecified Hepatic Coma Hepatocerebral Encephalopathy Hepatocerebral Intoxication
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers
Alcohol Dependence	Alcoholism Alcohol Dependence, Susceptibility To Aerodigestive Tract Cancer, Squamous Cell, Alcohol-Related, Protection Against Alcohol Dependence, Protection Against Alcoholism, Susceptibility To Alcoholic Intoxication, Chronic Pharyngeal Neoplasms Chronic Alcoholism Dipsomania Alcohol Addiction Ethanol Dependence Chronic Ethanolism Chronic Alcoholic Disease Nos Alcoholic Disease Nos Alcoholic
Aromatic L-Amino Acid Decarboxylase Deficiency	Aadc Deficiency Dopa Decarboxylase Deficiency Ddc Deficiency Aromatic Amino Acid Decarboxylase Deficiency Deficiency Of Aromatic-L-Amino-Acid Decarboxylase AADCD Aromatic-L-Amino-Acid Decarboxylase Deficiency Aromatic L-Amino-Acid Decarboxylase Deficiency
Amphetamine Abuse
Short-Rib Thoracic Dysplasia 4 With Or Without Polydactyly	Asphyxiating Thoracic Dystrophy 4 SRTD4 Atd4 Jatd Jeune Asphyxiating Thoracic Dystrophy Jeune Syndrome 4
Restless Legs Syndrome	Wed Willis-Ekbom Disease Restless Leg Syndrome Ekbom Syndrome Wittmaack-Ekbom Syndrome Willis Ekbom Disease Ekbom'S Syndrome Rls Restless Legs Restless Legs Syndrome, Susceptibility To
Parkinsonism	Parkinsonism-Plus Idiopathic Parkinsonism Primary Parkinsonism Paralysis Agitans Syndrome Parkinsonian Syndrome Trembling Paralysis Paralysis Agitans Shaking Palsy Shaking Paralysis
Schizophrenia	SCZD Schizophrenia With Or Without An Affective Disorder Schizophrenia 12 Schizophrenia, Susceptibility To Schizophrenia-1 Dementia Praecox Schizophrenia 1
Toxic Encephalopathy	Neurotoxicity Neurotoxicity Syndromes Neurotoxicity Syndrome Encephalopathy, Toxic
Multiple System Atrophy 1	Multiple System Atrophy Shy-Drager Syndrome Msa MSA1 Multiple System Atrophy 1, Susceptibility To Sporadic Olivopontocerebellar Atrophy Multisystem Atrophy Msa1, Susceptibility To Multiple System Atrophy, Susceptibility To Opca Progressive Autonomic Failure With Multiple System Atrophy Sds
Movement Disease	Movement Disorders Movement Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (16)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-14199	Selegiline hydrochloride	Inhibitor	99.96%	Unkown
HY-12723	Apomorphine		99.48%	Unkown
HY-14280	Entacapone	Inhibitor	99.97%	Yes
HY-N0159	Paeonol		99.98%	Unkown
HY-B1018A	Phenelzine sulfate	Inhibitor	99.96%	Unkown
HY-A0091A	Pargyline	Inhibitor	99.92%	Unkown
HY-70057	Safinamide	Inhibitor	99.86%	Yes
HY-A0091	Pargyline hydrochloride	Inhibitor	99.91%	Unkown
HY-70057A	Safinamide mesylate	Inhibitor	99.07%	Yes
HY-14855B	Tedizolid phosphate	Inhibitor	99.61%	Yes
HY-N0159R	Paeonol (Standard)		99.98%	Unkown
HY-B1558A	Bifemelane hydrochloride	Inhibitor	99.86%	Unkown
HY-14198	Selegiline	Inhibitor	/	Unkown
HY-14280R	Entacapone (Standard)	Inhibitor	99.24%	Unkown
HY-12723R	Apomorphine (Standard)		/	Unkown
HY-14280A	Entacapone sodium salt	Inhibitor	/	Unkown

Clinical Phase

Bioactive Molecules (10)

Cat. No.	Product Name	Effect	Purity	Phase
HY-103164A	8-(3-Chlorostyryl)caffeine		/	Phase 4
HY-N0529	Rosmarinic acid		99.73%	Phase 3
HY-154977	ETAP	Inhibitor	/	Phase 3
HY-129388B	Pulrodemstat benzenesulfonate	Inhibitor	99.64%	Phase 2
HY-112623	Vafidemstat	Inhibitor	98.03%	Phase 2
HY-129388A	Pulrodemstat	Inhibitor	98.86%	Phase 2
HY-10400	Ladostigil hemitartrate	Inhibitor	98.90%	Phase 2
HY-10399A	Ladostigil hydrochloride	Inhibitor	99.91%	Phase 2
HY-10399	Ladostigil	Inhibitor	/	Phase 2
HY-129388	Pulrodemstat Methylbenzenesulfonate	Inhibitor	/	Phase 2

Pre-clinical Phase

Bioactive Molecules (192)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-W008566	Norharmane	Inhibitor	99.93%	Unkown
HY-N7204	4-Hydroxyderricin		99.79%	Unkown
HY-W015490	1,4-Naphthoquinone	Inhibitor	99.97%	Unkown
HY-N0381	Maackiain		99.83%	Unkown
HY-110130	RN-1 dihydrochloride	Inhibitor	99.21%	Unkown
HY-E70074	Monoamine oxidase, plasma		/	Unkown
HY-103164	(E)-8-(3-Chlorostyryl)caffeine		99.4%	Unkown
HY-127109	Tisolagiline	Inhibitor	99.85%	Unkown
HY-N0026	2'-Acetylacteoside	Inhibitor	99.73%	Unkown
HY-19333	OG-L002	Inhibitor	99.55%	Unkown
HY-N0918	Desmethoxyyangonin		99.00%	Unkown
HY-N9540	Methyl citrate	Inhibitor	98.0%	Unkown
HY-119532	Nordeprenyl		95.13%	Unkown
HY-16677A	Mofegiline hydrochloride	Inhibitor	99.57%	Unkown
HY-114520	TT01001	Inhibitor	99.93%	Unkown
HY-127109A	Tisolagiline monomethylsulfate	Inhibitor	99.83%	Unkown
HY-131036	MAO-IN-M30 dihydrochloride	Inhibitor	98.48%	Unkown
HY-14201	Lazabemide	Inhibitor	99.95%	Unkown
HY-14203	(R)-Safinamide	Inhibitor	99.89%	Unkown
HY-D0004	Azure B	Inhibitor	99.87%	Unkown
HY-100588	VU0364770	Agonist	99.94%	Unkown
HY-149213	LSD1/TLK1-IN-1		99.20%	Unkown
HY-117173	(Rac)-Rasagiline	Inhibitor	≥97.0%	Unkown
HY-W655727	(-)-2-Phenylpropylamine	Inhibitor	98.44%	Unkown
HY-142026	Vitisin A		96%	Unkown
HY-121072	ASS234	Inhibitor	99.6%	Unkown
HY-127109B	Tisolagiline methylsulfate	Inhibitor	99.82%	Unkown
HY-W001601	Budipine	Antagonist	99.41%	Unkown
HY-W015490S	1,4-Naphthoquinone-d6	Inhibitor	99.20%	Unkown
HY-W049881	9-Methyl-β-carboline		99.86%	Unkown
HY-101578	2614W94	Inhibitor	99.76%	Unkown
HY-114620	MAO-B-IN-55	Inhibitor	98.10%	Unkown
HY-120419	PF9601N	Inhibitor	99.85%	Unkown
HY-120826	A2AAR/hMAO-B-IN-1	Inhibitor	99.0%	Unkown
HY-132907	MAO-B-IN-2	Inhibitor	99.05%	Unkown
HY-14280S	Entacapone-d10	Inhibitor	98.6%	Unkown
HY-146958	MAO-B-IN-8	Inhibitor	98.03%	Unkown
HY-156255	MAO-B-IN-25	Inhibitor	99.11%	Unkown
HY-70057S1	Safinamide-d4-1	Inhibitor	98.90%	Unkown
HY-B1018AS	Phenelzine-d5 sulfate	Inhibitor	99.97%	Unkown
HY-W010130	7-Hydroxy-3,4-dihydro-2(1H)-quinolinone	Inhibitor	99.96%	Unkown
HY-W845607	Milacemide	Inhibitor	98.04%	Unkown
HY-172451	MC4762	Inhibitor	/	Unkown
HY-100679B	(R)-Pirlindole mesylate	Inhibitor	/	Unkown
HY-103477	MAO-B-IN-51	Inhibitor	/	Unkown
HY-106972	SL-251131	Inhibitor	/	Unkown
HY-114915	PSB-1434	Inhibitor	98.05%	Unkown
HY-115986	MAO-B-IN-5	Inhibitor	/	Unkown
HY-115987	MAO-B-IN-6	Inhibitor	/	Unkown
HY-116097	PSB-1491	Inhibitor	/	Unkown
HY-116765	MAO-B-IN-35		/	Unkown
HY-117502	SL-25.1188	Inhibitor	/	Unkown
HY-123665	PSB-1410	Inhibitor	99.22%	Unkown
HY-129388C	Pulrodemstat hydrochloride	Inhibitor	/	Unkown
HY-129479	Almoxatone	Inhibitor	/	Unkown
HY-130205	Milacemide hydrochloride	Inhibitor	/	Unkown
HY-131660	MAO-B-IN-54	Inhibitor	/	Unkown
HY-134664	8α-(2-Methylacryloyloxy)-hirsutinolide-13-O-acetate	Inhibitor	/	Unkown
HY-136878	LSD1-IN-10	Inhibitor	/	Unkown
HY-14198B	(±)-Selegiline hydrochloride	Inhibitor	/	Unkown
HY-14202	Lazabemide hydrochloride	Inhibitor	95.0%	Unkown
HY-143244	Monoamine Oxidase B inhibitor 1	Inhibitor	/	Unkown
HY-143245	Monoamine Oxidase B inhibitor 2	Inhibitor	/	Unkown
HY-143329	MAO-B-IN-3	Inhibitor	/	Unkown
HY-143330	MAO-B-IN-4	Inhibitor	/	Unkown
HY-143438	2-PAT	Inhibitor	/	Unkown
HY-144673	LSD1-IN-12	Inhibitor	/	Unkown
HY-144756	LSD1-IN-15	Inhibitor	/	Unkown
HY-144757	LSD1-IN-16	Inhibitor	/	Unkown
HY-144758	LSD1-IN-17	Inhibitor	/	Unkown
HY-144824	Monoamine oxidase/Aromatase-IN-1	Inhibitor	/	Unkown
HY-145845	HDAC1/MAO-B-IN-1	Inhibitor	/	Unkown
HY-146149	MAO-B-IN-11	Inhibitor	/	Unkown
HY-146150	MAO-B-IN-12	Inhibitor	/	Unkown
HY-146312	AChE/BChE/MAO-B-IN-1	Inhibitor	99.57%	Unkown
HY-146314	MAO-B-IN-9	Inhibitor	99.70%	Unkown
HY-146347	MAO-B-IN-10	Inhibitor	/	Unkown
HY-146677	5-HT6R/MAO-B modulator 1		/	Unkown
HY-146762	MAO-B-IN-7	Inhibitor	/	Unkown
HY-147362	MAO-B-IN-14	Inhibitor	/	Unkown
HY-147953	MAO-B-IN-13	Inhibitor	/	Unkown
HY-149242	MAO-B-IN-20	Inhibitor	/	Unkown
HY-149477	IHC3	Inhibitor	/	Unkown
HY-149527	MAO-B-IN-23	Inhibitor	/	Unkown
HY-149528	MAO-B-IN-24	Inhibitor	/	Unkown
HY-149820	MAO-B-IN-22	Inhibitor	/	Unkown
HY-149978	LSD1-IN-26		/	Unkown
HY-149984	MAO-B-IN-21	Inhibitor	/	Unkown
HY-150563	Neuroinflammatory-IN-2	Inhibitor	/	Unkown
HY-151094	FTEAA	Inhibitor	/	Unkown
HY-151208	MAO-B-IN-16	Inhibitor	/	Unkown
HY-151209	MAO-B-IN-15	Inhibitor	/	Unkown
HY-151210	MAO-B-IN-17	Inhibitor	≥99.0%	Unkown
HY-151800	MAO-A/B-IN-2	Inhibitor	/	Unkown
HY-152109	AChE/MAO-IN-1	Inhibitor	/	Unkown
HY-152110	AChE/MAO-IN-2	Inhibitor	/	Unkown
HY-152111	AChE/MAO-B-IN-3	Inhibitor	/	Unkown
HY-152112	AChE/BChE/MAO-B-IN-2	Inhibitor	/	Unkown
HY-152113	AChE/BChE/MAO-B-IN-3	Inhibitor	/	Unkown
HY-152114	AChE/BChE/MAO-B-IN-4	Inhibitor	/	Unkown
HY-155330	PZ-1922		/	Unkown
HY-155330A	PZ-1922 free base		/	Unkown
HY-156348	MAO-B-IN-26	Inhibitor	/	Unkown
HY-157087	AChE/MAO-B-IN-4	Inhibitor	/	Unkown
HY-157089	AChE/MAO-B-IN-5	Inhibitor	/	Unkown
HY-157517	MAO-B-IN-29	Inhibitor	/	Unkown
HY-157934	MAO-IN-4	Inhibitor	/	Unkown
HY-157981	AChE-IN-60	Inhibitor	/	Unkown
HY-157982	BChE-IN-28	Inhibitor	/	Unkown
HY-158092	ChEs/MAOs-IN-2	Inhibitor	/	Unkown
HY-158732	MAO-B-IN-33	Inhibitor	/	Unkown
HY-159106	MeSeI		/	Unkown
HY-160002	MAO-B-IN-27	Inhibitor	/	Unkown
HY-161240	MAO-B-IN-30	Inhibitor	98.53%	Unkown
HY-162061	ChEs/MAOs-IN-1	Inhibitor	/	Unkown
HY-162303	C175-0062	Inhibitor	/	Unkown
HY-162606	MAO-A/B-IN-3	Inhibitor	/	Unkown
HY-162760	COMT-IN-1	Inhibitor	/	Unkown
HY-163322	MAO-A inhibitor 2	Inhibitor	/	Unkown
HY-163380	CA/MAO-B-IN-1	Inhibitor	98.34%	Unkown
HY-163474	MAO-B-IN-32	Inhibitor	/	Unkown
HY-163879	hMAO-B-IN-9	Inhibitor	/	Unkown
HY-16731	Sembragiline	Inhibitor	/	Unkown
HY-168138	MAO-B-IN-34	Inhibitor	/	Unkown
HY-168590	MAO-B-IN-36	Inhibitor	/	Unkown
HY-168728	MAO-B-IN-37	Inhibitor	/	Unkown
HY-169156	HDAC6-IN-49	Inhibitor	/	Unkown
HY-170487	MAO-B-IN-38	Inhibitor	/	Unkown
HY-170798	Monoamine Oxidase B inhibitor 6	Inhibitor	/	Unkown
HY-170887	MAO-B-IN-39		/	Unkown
HY-172101	AChE/MAO-B-IN-7	Inhibitor	/	Unkown
HY-172460	AChE/BChE/MAO-B-IN-5	Inhibitor	/	Unkown
HY-172461	MAO-IN-6	Inhibitor	/	Unkown
HY-173138	FCOB02	Ligand	/	Unkown
HY-173288	MAO-B-IN-40	Inhibitor	/	Unkown
HY-173336	MAO-B-IN-42	Inhibitor	/	Unkown
HY-174419	TFSeB		/	Unkown
HY-174834	MAO-B-IN-44	Inhibitor	/	Unkown
HY-175523	MAO-B-IN-48	Inhibitor	/	Unkown
HY-175524	BChE/MAO-B-IN-2	Inhibitor	/	Unkown
HY-176245	Illudinine	Inhibitor	/	Unkown
HY-176254	LSD1-IN-43	Inhibitor	/	Unkown
HY-176271	MAO-B-IN-45		/	Unkown
HY-178149	MAO-A/B-IN-5	Inhibitor	/	Unkown
HY-178352	MAO-B-IN-49		/	Unkown
HY-178454	Multitarget AD-IN-3	Inhibitor	/	Unkown
HY-179126	BChE/MAO-A-IN-1	Inhibitor	/	Unkown
HY-179167	K2V-9	Inhibitor	/	Unkown
HY-180114	NSS-18		/	Unkown
HY-180842	MAO-B-IN-50	Inhibitor	/	Unkown
HY-180843	Aβ/tau aggregation-IN-4	Inhibitor	/	Unkown
HY-181141	AChE/MAO-B-IN-8	Inhibitor	/	Unkown
HY-181146	MK-7762	Inhibitor	/	Unkown
HY-181861	AChE/MAO-B-IN-9	Inhibitor	/	Unkown
HY-181937	Multi-target kinase-IN-10	Inhibitor	/	Unkown
HY-182481	MD-230254	Inhibitor	/	Unkown
HY-182786	MAO-B-IN-56	Inhibitor	/	Unkown
HY-184026	MAO-B-IN-58	Inhibitor	/	Unkown
HY-184381	MAO-B-IN-61	Inhibitor	/	Unkown
HY-184503	MAO-B-IN-59	Inhibitor	/	Unkown
HY-D3221	MAO Probe 1		/	Unkown
HY-N15470	MAO-B-IN-52	Inhibitor	/	Unkown
HY-N15657	Geiparvarin		/	Unkown
HY-N1636	1-Methyl-2-nonyl-4(1H)-quinolone	Inhibitor	/	Unkown
HY-N1638	1-Methyl-2-undecyl-4(1H)-quinolone	Inhibitor	/	Unkown
HY-RS08022	MAOB Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08023	Maob Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS08024	Maob Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W008566S	Norharmane-13C		/	Unkown
HY-W035384	MAO-B ligand-1	Inhibitor	/	Unkown
HY-W083026	(E)-CHBO4	Inhibitor	97.04%	Unkown
HY-W205529	RO 16-6491 free base		/	Unkown
HY-W269511	NW-1689		99.54%	Unkown
HY-W335927	MAO-B-IN-19	Inhibitor	/	Unkown
HY-W628136	MAO-B-IN-47	Inhibitor	/	Unkown
HY-10399B	(S)-Ladostigil	Inhibitor	/	Unkown
HY-10400R	Ladostigil hemitartrate (Standard)	Inhibitor	/	Unkown
HY-105041	Tedizolid phosphate sodium	Inhibitor	/	Unkown
HY-123556	SZV-558	Inhibitor	/	Unkown
HY-124885	MD 220661	Inhibitor	/	Unkown
HY-129444	MD 780236 free base	Inhibitor	/	Unkown
HY-14198S	Selegiline-d5	Inhibitor	/	Unkown
HY-14199S	Selegiline-d5 hydrochloride	Inhibitor	/	Unkown
HY-164649	Atibeprone	Inhibitor	/	Unkown
HY-183437	MAO-B-IN-57	Inhibitor	/	Unkown
HY-19333A	OG-L002 hydrochloride	Inhibitor	/	Unkown
HY-70057S4	Safinamide-d5	Inhibitor	/	Unkown
HY-N12134	Methyl piperate	Inhibitor	/	Unkown
HY-N13041	Acacetin 7-O-(6-O-malonylglucoside)	Inhibitor	/	Unkown
HY-W029600	6,7-Dimethylisatin	Inhibitor	/	Unkown
HY-W700241	Norharman-d7	Inhibitor	/	Unkown
HY-W792513	WAY-620147	Inhibitor	98.0%	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	MAOB	VGNC	VGNC:42954
Rattus norvegicus	MAOB	RGD	RGD:3041
Mus musculus	MAOB	MGD	MGI:96916
Bos taurus	MAOB	VGNC	VGNC:31175
Felis catus	MAOB	VGNC	VGNC:68150
Macaca mulatta	MAOB	VGNC	VGNC:74488
Others	MAOB	NCBI