Pomalidomide

(Synonyms: CC-4047; Actimid)
39 Cited Publications
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Based on 39 publication(s) in Google Scholar

Pomalidomide (CC-4047) is an immunomodulatory agent. Pomalidomide downregulates TNF-alpha, IL-1, IL-11, and IL-12, upregulates IL-2, IL-5, and IL-10, and costimulates T cells. Pomalidomide inhibits the proliferation of T regulatory cells by reducing FOXP3/OX-40 expression and IL-2-mediated expansion. Pomalidomide inhibits CDK2/4/6 and p21WAF-1, causing cell cycle arrest. Pomalidomide can be used in research on myelofibrosis-associated anemia, multiple myeloma, and colorectal cancer.

For research use only. We do not sell to patients.

  • Purity : 99.88%
  • CAS No.: 19171-19-8
  • Formula: C13H11N3O4
  • Molecular Weight:273.24
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 1 year , -20°C, 6 months
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All FOXP Isoforms

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All Orexin Receptor (OX Receptor) Isoforms

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