YWHAE - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon Gene

Also Known as MDS; HEL2; MDCR; KCIP-1; 14-3-3E

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 7531

About YWHAE

Cytogenetic location: 17p13.3 Genomic coordinates (GRCh38): 17:1,344,275-1,400,222 (from NCBI)

This gene has 13 transcripts (splice variants), 1 gene allele, 217 orthologues, 6 paralogues and is associated with 72 phenotypes. Ubiquitous expression in brain (RPKM 317.4), kidney (RPKM 169.5) and 25 other tissues.

Summary

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both Plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of Insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung Cancer. Two transcript variants, one protein-coding and the Other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]

YWHAE Products (1)

mRNA Protein Name
NM_006761.5 NP_006752.1 2014/3/3 protein epsilon
Molecular Function GO Annotation Evidence Références Source
enables calcium channel inhibitor activity IDA
IDA: Inferred from direct assay
18029012 GOA
enables calcium channel regulator activity IDA
IDA: Inferred from direct assay
18029012 GOA
enables enzyme binding IPI
IPI: Inferred from physical interaction
10788521 GOA
enables histone deacetylase binding IPI
IPI: Inferred from physical interaction
10869435 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
17085597 GOA
enables phosphoprotein binding IPI
IPI: Inferred from physical interaction
10869435 GOA
enables phosphoserine residue binding IPI
IPI: Inferred from physical interaction
10869435 GOA
enables potassium channel regulator activity IDA
IDA: Inferred from direct assay
11953308 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
1266503 GOA
enables protein heterodimerization activity IPI
IPI: Inferred from physical interaction
11953308 GOA
enables protein sequestering activity IDA
IDA: Inferred from direct assay
11118213 GOA
enables scaffold protein binding IPI
IPI: Inferred from physical interaction
10409742 GOA
enables signaling adaptor activity IDA
IDA: Inferred from direct assay
22607805 GOA
enables transmembrane transporter binding IPI
IPI: Inferred from physical interaction
11953308 GOA
enables ubiquitin protein ligase binding IPI
IPI: Inferred from physical interaction
19725078 GOA
Cellular Component GO Annotation Evidence Références Source
is active in cytoplasm IDA
IDA: Inferred from direct assay
11118213 GOA
located in cytoplasm IDA
IDA: Inferred from direct assay
12917326 GOA
located in cytosol IDA
IDA: Inferred from direct assay
31906564 GOA
is active in endoplasmic reticulum IDA
IDA: Inferred from direct assay
35343654 GOA
located in nucleus IDA
IDA: Inferred from direct assay
12917326 GOA
colocalizes with plasma membrane IDA
IDA: Inferred from direct assay
18029012 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

YWHAE Protein Structure

14-3-3

14-3-3: 14-3-3 protein (4 - 237)

  • 0
  • 100
  • 200
  • 255 a.a.
Protein Preferred Names Protein Names

14-3-3 protein epsilon

  • 14-3-3 epsilon

YWHAE Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
YWHAE P62258 CHAF1A Homo sapiens Q13111 31980649
Intra
YWHAE P62258 CHAF1A Homo sapiens Q13111 20936779
Intra
YWHAE P62258 CHAF1A Homo sapiens Q13111 35271311
Intra
YWHAE P62258 CDK14 Homo sapiens O94921 36931259
Intra
YWHAE P62258 CDK14 Homo sapiens O94921
Y2H
16775625
Intra
YWHAE P62258 YAP1 Homo sapiens P46937 36931259
Intra
YWHAE P62258 YAP1 Homo sapiens P46937 35271311
Intra
YWHAE P62258 YAP1 Homo sapiens P46937 36931259
Intra
YWHAE P62258 GSK3A Homo sapiens P49840 36931259
Intra
YWHAE P62258 PPFIBP1 Homo sapiens Q86W92 36931259
Intra
YWHAE P62258 PPFIBP1 Homo sapiens Q86W92 35271311
Intra
YWHAE P62258 PPFIBP1 Homo sapiens Q86W92 36931259
Intra
YWHAE P62258 ISCU Homo sapiens Q9H1K1 35271311
Intra
YWHAE P62258 SAMD4B Homo sapiens Q5PRF9 35271311
Intra
YWHAE P62258 SAMD4A Homo sapiens Q9UPU9 36931259
Intra
YWHAE P62258 SH3BP4 Homo sapiens Q9P0V3 35271311
Intra
YWHAE P62258 SH3BP4 Homo sapiens Q9P0V3 36931259
Intra
YWHAE P62258 SH3BP4 Homo sapiens Q9P0V3 20936779
Intra
YWHAE P62258 RAB11FIP2 Homo sapiens Q7L804 35271311
Intra
YWHAE P62258 RAB11FIP2 Homo sapiens Q7L804 32296183
Intra
YWHAE P62258 RAB11FIP2 Homo sapiens Q7L804 36931259
Intra
YWHAE P62258 STK32C Homo sapiens Q86UX6 36931259
Intra
YWHAE P62258 RALGPS2 Homo sapiens Q86X27 35271311
Intra
YWHAE P62258 USP8 Homo sapiens P40818 36931259
Intra
YWHAE P62258 USP8 Homo sapiens P40818 35271311
Intra
YWHAE P62258 CDC25B Homo sapiens P30305
Y2H
7644510
Intra
YWHAE P62258 CDC25B Homo sapiens P30305 35271311
Intra
YWHAE P62258 EPB41L2 Homo sapiens O43491 36931259
Intra
YWHAE P62258 LARP1 Homo sapiens Q6PKG0 36931259
Intra
YWHAE P62258 LARP1 Homo sapiens Q6PKG0 36931259
Intra
YWHAE P62258 LARP1 Homo sapiens Q6PKG0 35271311
Intra
YWHAE P62258 PAK6 Homo sapiens Q9NQU5 36931259
Intra
YWHAE P62258 KIAA0930 Homo sapiens Q6ICG6 36931259
Intra
YWHAE P62258 KIAA0930 Homo sapiens Q6ICG6 35271311
Intra
YWHAE P62258 ARHGEF16 Homo sapiens Q5VV41 36931259
Intra
YWHAE P62258 FOXO1 Homo sapiens Q12778 35271311
Intra
YWHAE P62258 FOXO1 Homo sapiens Q12778 36931259
Intra
YWHAE P62258 NUAK2 Homo sapiens Q9H093 36931259
Intra
YWHAE P62258 CCDC125 Homo sapiens Q86Z20 32296183
Intra
YWHAE P62258 CDK3 Homo sapiens Q00526 36931259
Intra
YWHAE P62258 TNK1 Homo sapiens Q13470 36931259
Intra
YWHAE P62258 TESK2 Homo sapiens Q96S53 36931259
Intra
YWHAE P62258 TESK2 Homo sapiens Q96S53 36931259
Intra
YWHAE P62258 TESK2 Homo sapiens Q96S53 35271311
Intra
YWHAE P62258 RPS6KA2 Homo sapiens Q15349 36931259
Intra
YWHAE P62258 LIMK2 Homo sapiens P53671 36931259
Intra
YWHAE P62258 RICTOR Homo sapiens Q6R327 36931259
Intra
YWHAE P62258 RICTOR Homo sapiens Q6R327 35271311
Intra
YWHAE P62258 KLC3 Homo sapiens Q6P597 35271311
Intra
YWHAE P62258 KIF1C Homo sapiens O43896 36931259
Intra
YWHAE P62258 KIF1C Homo sapiens O43896 35271311
Intra
YWHAE P62258 KIF1C Homo sapiens O43896
Y2H
21988832
Intra
YWHAE P62258 ZFP36L2 Homo sapiens P47974 35271311
Intra
YWHAE P62258 ZFP36L2 Homo sapiens P47974 36931259
Intra
YWHAE P62258 FOXO3 Homo sapiens O43524 35271311
Intra
YWHAE P62258 FOXO3 Homo sapiens O43524 36931259
Intra
YWHAE P62258 CRTC1 Homo sapiens Q6UUV9 36931259
Intra
YWHAE P62258 CRTC1 Homo sapiens Q6UUV9 35271311
Intra
YWHAE P62258 CRTC1 Homo sapiens Q6UUV9 36931259
Intra
YWHAE P62258 PLEKHA7 Homo sapiens Q6IQ23 36931259
Intra
YWHAE P62258 PLEKHA7 Homo sapiens Q6IQ23 36931259
Intra
YWHAE P62258 PLEKHA7 Homo sapiens Q6IQ23 35271311
Intra
YWHAE P62258 MINK1 Homo sapiens Q8N4C8 36931259
Intra
YWHAE P62258 FAM110B Homo sapiens Q8TC76 35271311
Intra
YWHAE P62258 TFEB Homo sapiens P19484 36931259
Intra
YWHAE P62258 TFEB Homo sapiens P19484 35271311
Intra
YWHAE P62258 CEP112 Homo sapiens Q8N8E3 36931259
Intra
YWHAE P62258 CEP112 Homo sapiens Q8N8E3 36931259
Intra
YWHAE P62258 PTK2B Homo sapiens Q14289 36931259
Intra
YWHAE P62258 ARHGEF2 Homo sapiens Q92974 36931259
Intra
YWHAE P62258 ARHGEF2 Homo sapiens Q92974 36931259
Intra
YWHAE P62258 ARHGEF2 Homo sapiens Q92974 35271311
Intra
YWHAE P62258 YWHAH Homo sapiens Q04917 35271311
Intra
YWHAE P62258 YWHAH Homo sapiens Q04917 31980649
Intra
YWHAE P62258 YWHAH Homo sapiens Q04917 36931259
Intra
YWHAE P62258 MAP3K3 Homo sapiens Q99759 36931259
Intra
YWHAE P62258 MAP3K3 Homo sapiens Q99759 35271311
Intra
YWHAE P62258 IKBKE Homo sapiens Q14164 36931259
Intra
YWHAE P62258 NAV1 Homo sapiens Q8NEY1 36931259
Intra
YWHAE P62258 HDAC4 Homo sapiens P56524 36931259
Intra
YWHAE P62258 HDAC4 Homo sapiens P56524 11504882
Intra
YWHAE P62258 HDAC4 Homo sapiens P56524 35271311
Intra
YWHAE P62258 SORBS2 Homo sapiens O94875 36931259
Intra
YWHAE P62258 SORBS2 Homo sapiens O94875 16189514
Intra
YWHAE P62258 SORBS2 Homo sapiens O94875 36931259
Intra
YWHAE P62258 SH3RF1 Homo sapiens Q7Z6J0 36931259
Intra
YWHAE P62258 CGNL1 Homo sapiens Q0VF96 20936779
Intra
YWHAE P62258 CGNL1 Homo sapiens Q0VF96 36931259
Intra
YWHAE P62258 YWHAZ Homo sapiens P63104 31980649
Intra
YWHAE P62258 YWHAZ Homo sapiens P63104 16376338
Intra
YWHAE P62258 YWHAZ Homo sapiens P63104 36931259
Intra
YWHAE P62258 YWHAZ Homo sapiens P63104 35271311
Intra
YWHAE P62258 YWHAZ Homo sapiens P63104 21988832
Intra
YWHAE P62258 LUZP1 Homo sapiens Q86V48 36931259
Intra
YWHAE P62258 SRSF10 Homo sapiens O75494 31980649
Intra
YWHAE P62258 YWHAG Homo sapiens P61981 31980649
Intra
YWHAE P62258 YWHAG Homo sapiens P61981 26184334
Intra
YWHAE P62258 YWHAG Homo sapiens P61981 36931259
Intra
YWHAE P62258 YWHAG Homo sapiens P61981 36931259
Intra
YWHAE P62258 YWHAG Homo sapiens P61981
Y2H
21988832
Intra
YWHAE P62258 YWHAG Homo sapiens P61981 35271311
Intra
YWHAE P62258 YWHAG Homo sapiens P61981 20936779
Intra
YWHAE P62258 IRS4 Homo sapiens O14654 36931259
Intra
YWHAE P62258 IRS4 Homo sapiens O14654 36931259
Intra
YWHAE P62258 MYLK2 Homo sapiens Q9H1R3 36931259
Intra
YWHAE P62258 MAP3K2 Homo sapiens Q9Y2U5 9452471
Intra
YWHAE P62258 MAP3K2 Homo sapiens Q9Y2U5 9452471
Intra
YWHAE P62258 MAP3K2 Homo sapiens Q9Y2U5 35271311
Intra
YWHAE P62258 MAP3K14 Homo sapiens Q99558 36931259
Intra
YWHAE P62258 RIPK2 Homo sapiens O43353 36931259
Intra
YWHAE P62258 YWHAB Homo sapiens P31946 36931259
Intra
YWHAE P62258 YWHAB Homo sapiens P31946 35271311
Intra
YWHAE P62258 YWHAB Homo sapiens P31946 31980649
Intra
YWHAE P62258 YWHAB Homo sapiens P31946 36931259
Intra
YWHAE P62258 YWHAQ Homo sapiens P27348 36931259
Intra
YWHAE P62258 YWHAQ Homo sapiens P27348 31980649
Intra
YWHAE P62258 YWHAQ Homo sapiens P27348 17085597
Intra
YWHAE P62258 YWHAQ Homo sapiens P27348 35271311
Intra
YWHAE P62258 ARAF Homo sapiens P10398 20936779
Intra
YWHAE P62258 ARAF Homo sapiens P10398 35271311
Intra
YWHAE P62258 ARAF Homo sapiens P10398 36931259
Intra
YWHAE P62258 BRAF Homo sapiens P15056 36931259
Intra
YWHAE P62258 RAF1 Homo sapiens P04049
Y2H
7644510
Intra
YWHAE P62258 RAF1 Homo sapiens P04049 36931259
Intra
YWHAE P62258 RAF1 Homo sapiens P04049 36931259
Intra
YWHAE P62258 RAF1 Homo sapiens P04049 11697890
Intra
YWHAE P62258 RAF1 Homo sapiens P04049 35271311
Intra
YWHAE P62258 CEP95 Homo sapiens Q96GE4 20936779
Intra
YWHAE P62258 CEP95 Homo sapiens Q96GE4 35271311
Intra
YWHAE P62258 CEP95 Homo sapiens Q96GE4 36931259
Intra
YWHAE P62258 ABL1 Homo sapiens P00519 35271311
Intra
YWHAE P62258 ABL1 Homo sapiens P00519 36931259
Intra
YWHAE P62258 MAPK4 Homo sapiens P31152 36931259
Intra
YWHAE P62258 DYRK4 Homo sapiens Q9NR20 36931259
Intra
YWHAE P62258 MAP3K9 Homo sapiens P80192 36931259
Intra
YWHAE P62258 MAP3K9 Homo sapiens P80192 36931259
Intra
YWHAE P62258 LIMK1 Homo sapiens P53667 36931259
Intra
YWHAE P62258 APAF1 Homo sapiens O14727 22246185
Intra
YWHAE P62258 WNK1 Homo sapiens Q9H4A3 35271311
Intra
YWHAE P62258 WNK1 Homo sapiens Q9H4A3 20936779
Intra
YWHAE P62258 WNK1 Homo sapiens Q9H4A3 36931259
Intra
YWHAE P62258 WNK1 Homo sapiens Q9H4A3 36931259
Intra
YWHAE P62258 KIF1B Homo sapiens O60333 36931259
Intra
YWHAE P62258 KIF1B Homo sapiens O60333 35271311
Intra
YWHAE P62258 KIF1B Homo sapiens O60333 36931259
Intra
YWHAE P62258 IGF1R Homo sapiens P08069
Y2H
9111084
Intra
YWHAE P62258 IGF1R Homo sapiens P08069 36931259
Intra
YWHAE P62258 IGF1R Homo sapiens P08069 9111084
Intra
YWHAE P62258 MAP3K5 Homo sapiens Q99683 35271311
Intra
YWHAE P62258 MAP3K5 Homo sapiens Q99683 31980649
Intra
YWHAE P62258 SFN Homo sapiens P31947 31980649
Intra
YWHAE P62258 KSR1 Homo sapiens Q8IVT5 36931259
Intra
YWHAE P62258 KSR1 Homo sapiens Q8IVT5 36931259
Intra
YWHAE P62258 KSR1 Homo sapiens Q8IVT5 35271311
Intra
YWHAE P62258 ABLIM1 Homo sapiens O14639 36931259
Intra
YWHAE P62258 ABLIM1 Homo sapiens O14639 35271311
Intra
YWHAE P62258 ABLIM1 Homo sapiens O14639 36931259
Intra
YWHAE P62258 MAST2 Homo sapiens Q6P0Q8 35271311
Intra
YWHAE P62258 MAST2 Homo sapiens Q6P0Q8 36931259
Intra
YWHAE P62258 IRS1 Homo sapiens P35568 9111084
Intra
YWHAE P62258 IRS1 Homo sapiens P35568 9312143
Intra
YWHAE P62258 IRS1 Homo sapiens P35568
Y2H
9111084
Intra
YWHAE P62258 CBL Homo sapiens P22681 36931259
Intra
YWHAE P62258 CBL Homo sapiens P22681 35271311
Intra
YWHAE P62258 TBC1D4 Homo sapiens O60343 36931259
Intra
YWHAE P62258 TBC1D4 Homo sapiens O60343 35271311
Intra
YWHAE P62258 BAIAP2 Homo sapiens Q9UQB8 36931259
Intra
YWHAE P62258 BAIAP2 Homo sapiens Q9UQB8 36931259
Intra
YWHAE P62258 BAIAP2 Homo sapiens Q9UQB8 35271311
Intra
YWHAE P62258 DISC1 Homo sapiens Q9NRI5
Y2H
17043677
Intra
YWHAE P62258 LRRK2 Homo sapiens Q5S007 20642453
Intra
YWHAE P62258 GRIP1 Homo sapiens Q9Y3R0 36931259
Intra
YWHAE P62258 GRIP1 Homo sapiens Q9Y3R0 35271311
Intra
YWHAE P62258 KANK1 Homo sapiens Q14678-2 18458160
Intra
YWHAE P62258 KANK1 Homo sapiens Q14678-2 18458160
Intra
YWHAE P62258 CDK17 Homo sapiens Q00537 35271311
Intra
YWHAE P62258 CDK17 Homo sapiens Q00537 36931259
Intra
YWHAE P62258 SRPK3 Homo sapiens Q9UPE1 36931259
Intra
YWHAE P62258 MUSK Homo sapiens O15146 36931259
Intra
YWHAE P62258 TSSK1B Homo sapiens Q9BXA7 36931259
Intra
YWHAE P62258 ALPK1 Homo sapiens Q96QP1 36931259
Cross
YWHAE P62258 Rnd3 Mus musculus P61588 23622247
Intra
YWHAE P62258 BAD Homo sapiens Q92934 36931259
Intra
YWHAE P62258 BAD Homo sapiens Q92934
Y2H
21988832
Intra
YWHAE P62258 PKP2 Homo sapiens Q99959 36931259
Intra
YWHAE P62258 PKP2 Homo sapiens Q99959 35271311
Intra
YWHAE P62258 PRKCE Homo sapiens Q02156 36931259
Intra
YWHAE P62258 MARK3 Homo sapiens P27448 36931259
Intra
YWHAE P62258 MARK3 Homo sapiens P27448 36931259
Intra
YWHAE P62258 MARK3 Homo sapiens P27448 35271311
Intra
YWHAE P62258 PAK4 Homo sapiens O96013 35271311
Intra
YWHAE P62258 PAK4 Homo sapiens O96013 36931259
Intra
YWHAE P62258 WDR62 Homo sapiens O43379 36931259
Intra
YWHAE P62258 WDR62 Homo sapiens O43379 35271311
Intra
YWHAE P62258 ACD Homo sapiens Q96AP0 21044950
Intra
YWHAE P62258 NEDD4L Homo sapiens Q96PU5 36931259
Intra
YWHAE P62258 NEDD4L Homo sapiens Q96PU5 36931259
Intra
YWHAE P62258 NEDD4L Homo sapiens Q96PU5 35271311
Intra
YWHAE P62258 NEDD4L Homo sapiens Q96PU5 31980649
Intra
YWHAE P62258 PRAG1 Homo sapiens Q86YV5 36931259
Intra
YWHAE P62258 ZNF598 Homo sapiens Q86UK7 35271311
Intra
YWHAE P62258 PLK2 Homo sapiens Q9NYY3 36931259
Intra
YWHAE P62258 ITPRID2 Homo sapiens P28290 36931259
Intra
YWHAE P62258 ITPRID2 Homo sapiens P28290 35271311
Intra
YWHAE P62258 CDK16 Homo sapiens Q00536 35271311
Intra
YWHAE P62258 KLC2 Homo sapiens Q9H0B6 36931259
Intra
YWHAE P62258 KLC2 Homo sapiens Q9H0B6 36931259
Intra
YWHAE P62258 KLC2 Homo sapiens Q9H0B6 35271311
Intra
YWHAE P62258 PCM1 Homo sapiens Q15154 36931259
Intra
YWHAE P62258 PLK4 Homo sapiens O00444 35271311
Intra
YWHAE P62258 CDK18 Homo sapiens Q07002 35271311
Intra
YWHAE P62258 CDK18 Homo sapiens Q07002 36931259
Intra
YWHAE P62258 CDC25A Homo sapiens P30304
Y2H
7644510
Intra
YWHAE P62258 CDC25A Homo sapiens P30304 14559997
Intra
YWHAE P62258 CDC25A Homo sapiens P30304 14559997
Intra
YWHAE P62258 CDC25A Homo sapiens P30304 35271311
Intra
YWHAE P62258 WWTR1 Homo sapiens Q9GZV5 18227151
Intra
YWHAE P62258 CSNK1E Homo sapiens P49674 36931259
Intra
YWHAE P62258 CSNK1E Homo sapiens P49674 36931259
Intra
YWHAE P62258 CSNK1D Homo sapiens P48730 36931259
Intra
YWHAE P62258 GRB10 Homo sapiens Q13322 35271311
Intra
YWHAE P62258 TSSK2 Homo sapiens Q96PF2 36931259
Intra
YWHAE P62258 CLASP1 Homo sapiens Q7Z460 36931259
Intra
YWHAE P62258 CLASP1 Homo sapiens Q7Z460 36931259
Intra
YWHAE P62258 CLASP1 Homo sapiens Q7Z460 35271311
Intra
YWHAE P62258 CLASP2 Homo sapiens O75122 36931259
Intra
YWHAE P62258 CLASP2 Homo sapiens O75122 36931259
Intra
YWHAE P62258 CLASP2 Homo sapiens O75122 35271311
Intra
YWHAE P62258 ATXN1 Homo sapiens P54253 35271311
Intra
YWHAE P62258 ATXN1 Homo sapiens P54253 12757707
Intra
YWHAE P62258 ATXN1 Homo sapiens P54253 12757707
Intra
YWHAE P62258 ATXN1 Homo sapiens P54253 36931259
Intra
YWHAE P62258 NDE1 Homo sapiens Q9NXR1 35271311
Intra
YWHAE P62258 CBY1 Homo sapiens Q9Y3M2 35271311
Intra
YWHAE P62258 CBY1 Homo sapiens Q9Y3M2
TAP
27173435
Intra
YWHAE P62258 PUM1 Homo sapiens Q14671 36931259
Intra
YWHAE P62258 PUM1 Homo sapiens Q14671 36931259
Intra
YWHAE P62258 KLC4 Homo sapiens Q9NSK0 36931259
Intra
YWHAE P62258 KLC4 Homo sapiens Q9NSK0 35271311
Intra
YWHAE P62258 KLC4 Homo sapiens Q9NSK0 36931259
Intra
YWHAE P62258 PRKCG Homo sapiens P05129 36931259
Intra
YWHAE P62258 ITK Homo sapiens Q08881 36931259
Intra
YWHAE P62258 CDC25C Homo sapiens P30307 36931259
Intra
YWHAE P62258 CDC25C Homo sapiens P30307 19331823
Intra
YWHAE P62258 CDC25C Homo sapiens P30307 35271311
Cross
YWHAE P62258 O92972-PRO_0000278742 Hepatitis C virus O92972-PRO_0000278742 10644344
Cross
YWHAE P62258 O92972-PRO_0000278742 Hepatitis C virus O92972-PRO_0000278742 10644344
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant YWHAE Proteins

Cat. No. Nom du produit Accession Pureté
HY-P7445 14-3-3 epsilon Protein, Human (GST) P62258/NP_006752.1 (M1-Q255) ≥ 90%, as determined by reducing SDS-PAGE.

YWHAE Anticorps

Cat. No. Nom du produit Application Reactivity
HY-P82884 14-3-3 epsilon Antibody (YA2629) WB, IHC-P, ICC/IF, FC Human, Mouse, Rat

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  • Endometrial Stromal Sarcoma, High Grade

  • Undifferentiated Endometrial Sarcoma

  • Stromal Sarcoma Of The Corpus Uteri

  • Sarcoma Endometrial Stromal

  • Sarcoma, Endometrial Stromal

  • Undifferentiated Stromal Sarcoma

Kidney Clear Cell Sarcoma
  • Clear Cell Sarcoma Of Kidney

  • Childhood Kidney Clear Cell Sarcoma

  • Renal Clear Cell Sarcoma

  • Ccsk

  • Clear Cell Sarcoma Of The Kidney

Distal 17p13.3 Microdeletion Syndrome
  • Distal Del(17)(P13.3 )

  • Distal Monosomy 17p13.3

Miller-Dieker Lissencephaly Syndrome
  • Miller-Dieker Syndrome

  • Mds

  • MDLS

  • Miller Dieker Syndrome

  • Classical Lissencephaly Syndrome

  • Lissencephaly Due To 17p13.3 Deletion

  • Monosomy 17p13.3

  • Telomeric Deletion 17p

  • Classical Lissencephaly

Chromosome 17p13.3, Centromeric, Duplication Syndrome
  • Chromosome 17p13.3 Duplication Syndrome

  • 17p13.3 Duplication Syndrome

  • 17p13.3 Microduplication Syndrome

  • Trisomy 17p13.3

  • Chromosome 17p13.3 Centromeric Duplication Syndrome

  • Dup(17)(P13.3)

Endometrial Stromal Tumor
  • Endometrial Stromal Neoplasm

  • Endometrial Stromal Tumors

Endometrial Stromal Nodule
Lissencephaly
  • Pachygyria

  • Broad Gyri Of Cerebrum

  • Large Gyri Of Cerebrum

  • Macrogyria

Kidney Sarcoma
  • Renal Sarcoma

  • Sarcoma Of Kidney

Vaginal Endometrial Stromal Sarcoma
Vagina Sarcoma
  • Sarcoma Of The Vagina

  • Vaginal Sarcoma

Myxoid Leiomyosarcoma
  • Leiomyosarcoma, Myxoid

Lissencephaly 4
  • LIS4

  • Lissencephaly 4 With Microcephaly

  • Microlissencephaly

  • Lissencephaly, Type 4

Cellular Congenital Mesoblastic Nephroma
Adenosarcoma
  • Mullerian Adenosarcoma

Clear Cell Sarcoma
  • Sarcoma, Clear Cell

  • Adult Soft Part Clear Cell Sarcoma

  • Clear Cell Sarcoma Of Soft Parts

  • Malignant Melanoma Of Soft Parts

  • Malignant Melanoma Of Soft Tissues

  • Melanoma, Malignant, Of Soft Parts

  • Sarcoma Clear Cell

Congenital Mesoblastic Nephroma
  • Mesoblastic Nephroma

  • Nephroma, Mesoblastic

Lissencephaly 1
  • LIS1

  • Classic Lissencephaly

  • Ils

  • Subcortical Laminar Heterotopia

  • Lissencephaly Due To Lis1 Mutation

  • Lissencephaly Sequence, Isolated

  • Lissencephaly, Classic

  • Pafah1b1-Related Lissencephaly

  • Classical Lissencephaly

  • Lissencephaly Type 1

  • Lissencephaly-1

  • Subcortical Band Heterotopia

  • Double Cortex

  • Lissencephaly Classic

  • Lissencephaly Sequence Isolated

  • Isolated Lissencephaly Sequence

  • Type 1 Lissencephaly

  • Lissencephaly Syndrome Type 1

  • SBH

  • Sclh

  • Lissencephaly, Type 1

  • Type I Lissencephaly

Sudden Infant Death Syndrome
  • SIDS

  • Sudden Infant Death Syndrome, Susceptibility To

  • Cot Death

  • Crib Death

  • Sudden Death Of Nonspecific Cause In Infancy

  • Sudden Infant Death

  • Death, Sudden, Syndrome, Infant

Potocki-Lupski Syndrome
  • PTLS

  • Chromosome 17p11.2 Duplication Syndrome

  • 17p11.2 Microduplication Syndrome

  • Duplication 17p11.2 Syndrome

  • Trisomy 17p11.2

  • Potocki-Lupski Syndrome (Dup(17)(P11.2p11.2))

  • 17p11.2 Duplication Syndrome

  • Dup(17)(P11.2p11.2)

  • Pls

  • Chromosome 17, Trisomy 17p11 2

Lung Cancer
  • Lung Carcinoma

  • Non-Small Cell Lung Carcinoma

  • Lung Cancer, Susceptibility To

  • Lung Cancer, Protection Against

  • Adenocarcinoma Of Lung, Somatic

  • Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer

  • Lung Neoplasm

  • Carcinoma Of Lung

  • Lung Non-Small Cell Carcinoma

  • Non-Small Cell Lung Cancer

  • Nsclc

  • Lung Neoplasms

  • Malignant Neoplasm Of Lung

  • Alveolar Cell Carcinoma

  • Nonsmall Cell Lung Cancer, Somatic

  • Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In

  • Nonsmall Cell Lung Cancer, Susceptibility To

  • Lung Cancer, Somatic

  • Lung Cancer, Resistance To

  • Cancer Of Lung

  • Cancer Of Bronchus

  • Cancer Of The Lung

  • Lung Malignancies

  • Lung Malignant Tumors

  • Malignant Lung Tumor

  • Malignant Tumor Of Lung

  • Pulmonary Cancer

  • Pulmonary Carcinoma

  • Pulmonary Neoplasms

  • Respiratory Carcinoma

  • LNCR

  • Adenocarcinoma Of Lung

  • Neoplasm Of Lung

  • Cancer Lung

  • Carcinoma Non-Small Cell Lung

  • Carcinoma, Non-Small-Cell Lung

  • Lung Cancers

  • Lung Carcinomas

  • Cancer, Lung

  • Cancer, Lung, Non-Small Cell

  • Primary Malignant Neoplasm Of Lung

  • Bronchioloalveolar Adenocarcinoma

Kidney Fibrosarcoma
  • Fibrosarcoma Of The Kidney

Polymicrogyria, Bilateral Perisylvian, X-Linked
  • Bilateral Perisylvian Polymicrogyria

  • Polymicrogyria, Bilateral Perisylvian

  • Pmgx

  • Perisylvian Syndrome, Congenital Bilateral

  • Cbps

  • Congenital Bilateral Perisylvian Syndrome

  • Perisylvian Syndrome

  • BPPX

  • Bpp

Retinitis Pigmentosa
  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1

Schizophrenia
  • SCZD

  • Schizophrenia With Or Without An Affective Disorder

  • Schizophrenia 12

  • Schizophrenia, Susceptibility To

  • Schizophrenia-1

  • Dementia Praecox

  • Schizophrenia 1

Congenital Nervous System Abnormality
  • Congenital Neurologic Anomaly

  • Congenital Nervous System Disorder

Left Ventricular Noncompaction
  • Noncompaction Cardiomyopathy

  • Left Ventricular Hypertrabeculation

  • Lvnc

  • Spongy Myocardium

  • Isolated Noncompaction Of The Ventricular Myocardium

  • Left Ventricular Myocardial Noncompaction Cardiomyopathy

  • Fetal Myocardium

  • Honeycomb Myocardium

  • Hypertrabeculation Syndrome

  • Left Ventricular Non-Compaction

  • Lvht

  • Non-Compaction Of The Left Ventricular Myocardium

  • Ventricular Noncompaction, Left

  • Non-Compaction Cardiomyopathy

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus YWHAE VGNC VGNC:37045
Rattus norvegicus YWHAE RGD RGD:62000
Macaca mulatta YWHAE VGNC VGNC:104677
Mus musculus YWHAE MGD MGI:894689
Others YWHAE NCBI