BRAF - B-Raf proto-oncogene, serine/threonine kinase Gene

Also Known as NS7; B-raf; BRAF1; RAFB1; B-RAF1; BRAF-1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 673

About BRAF

Cytogenetic location: 7q34 Genomic coordinates (GRCh38): 7:140,713,328-140,924,929 (from NCBI)

This gene has 21 transcripts (splice variants), 211 orthologues, 23 paralogues and is associated with 245 phenotypes. Ubiquitous expression in testis (RPKM 6.6), brain (RPKM 5.3) and 25 other tissues.

Summary

This gene encodes a protein belonging to the Raf family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various Other cancers as well, including non-Hodgkin lymphoma, colorectal Cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]

BRAF Products (20)

mRNA	Protein	Name
XM_047420766.1	XP_047276722.1	serine/threonine-protein kinase B-raf isoform X2
NM_001378467.1	NP_001365396.1	serine/threonine-protein kinase B-raf isoform 5
XM_047420767.1	XP_047276723.1	serine/threonine-protein kinase B-raf isoform X3
NM_004333.6	NP_004324.2	serine/threonine-protein kinase B-raf isoform 1
NR_148928.2
XM_017012559.2	XP_016868048.1	serine/threonine-protein kinase B-raf isoform X1
XM_047420770.1	XP_047276726.1	serine/threonine-protein kinase B-raf isoform X6
NM_001354609.2	NP_001341538.1	serine/threonine-protein kinase B-raf isoform 2
NM_001374244.1	NP_001361173.1	serine/threonine-protein kinase B-raf isoform 3
NM_001378475.1	NP_001365404.1	serine/threonine-protein kinase B-raf isoform 13
NM_001378474.1	NP_001365403.1	serine/threonine-protein kinase B-raf isoform 12
NM_001374258.1	NP_001361187.1	serine/threonine-protein kinase B-raf isoform 4
XM_047420769.1	XP_047276725.1	serine/threonine-protein kinase B-raf isoform X5
NM_001378473.1	NP_001365402.1	serine/threonine-protein kinase B-raf isoform 11
NM_001378470.1	NP_001365399.1	serine/threonine-protein kinase B-raf isoform 8
NM_001378468.1	NP_001365397.1	serine/threonine-protein kinase B-raf isoform 6
XM_047420768.1	XP_047276724.1	serine/threonine-protein kinase B-raf isoform X4
NM_001378472.1	NP_001365401.1	serine/threonine-protein kinase B-raf isoform 10
NM_001378469.1	NP_001365398.1	serine/threonine-protein kinase B-raf isoform 7
NM_001378471.1	NP_001365400.1	serine/threonine-protein kinase B-raf isoform 9

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	References	Source
enables MAP kinase kinase activity	IMP IMP: Inferred from mutant phenotype	29433126	GOA
enables calcium ion binding	IDA IDA: Inferred from direct assay	18567582	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	16858395	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	12620389	GOA
enables protein kinase activity	IDA IDA: Inferred from direct assay	17563371	GOA
enables protein serine/threonine kinase activity	IDA IDA: Inferred from direct assay	18567582	GOA
enables scaffold protein binding	IPI IPI: Inferred from physical interaction	18567582	GOA
NOT enables small GTPase binding	IPI IPI: Inferred from physical interaction	12194967	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in MAPK cascade	IDA IDA: Inferred from direct assay	18567582	GOA
involved in cellular response to calcium ion	IDA IDA: Inferred from direct assay	18567582	GOA
involved in epidermal growth factor receptor signaling pathway	IDA IDA: Inferred from direct assay	18567582	GOA
involved in establishment of protein localization to membrane	IDA IDA: Inferred from direct assay	23010278	GOA
involved in negative regulation of apoptotic process	IDA IDA: Inferred from direct assay	19667065	GOA
involved in positive regulation of D-glucose transmembrane transport	IDA IDA: Inferred from direct assay	23010278	GOA
involved in positive regulation of ERK1 and ERK2 cascade	IDA IDA: Inferred from direct assay	22065586	GOA
involved in positive regulation of gene expression	IMP IMP: Inferred from mutant phenotype	22065586	GOA
involved in positive regulation of peptidyl-serine phosphorylation	IDA IDA: Inferred from direct assay	19667065	GOA
involved in protein phosphorylation	IDA IDA: Inferred from direct assay	17563371	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BRAF Protein Structure

RBD

C1_1

Pkinase_Tyr

0
200
400
600
766 a.a.

Protein Preferred Names	Protein Names
serine/threonine-protein kinase B-raf	94 kDa B-raf protein B-Raf proto-oncogene serine/threonine-protein kinase (p94) B-Raf serine/threonine-protein murine sarcoma viral (v-raf) oncogene homolog B1 proto-oncogene B-Raf v-raf murine sarcoma viral oncogene homolog B v-raf murine sarcoma viral oncogene homolog B1

BRAF Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	BRAF	P15056	MAP2K2	Homo sapiens	P36507	TAP	17979178
Intra	BRAF	P15056	MAP2K2	Homo sapiens	P36507	Anti Tag CoIP	31980649
Intra	BRAF	P15056	MAP2K2	Homo sapiens	P36507	Pull Down	32707033
Intra	BRAF	P15056	MAP2K2	Homo sapiens	P36507	Anti Tag CoIP	33961781
Intra	BRAF	P15056	MAP2K2	Homo sapiens	P36507	Anti Bait CoIP	25600339
Intra	BRAF	P15056	MAP2K2	Homo sapiens	P36507	Anti Tag CoIP	28514442
Intra	BRAF	P15056	RPS6KA2	Homo sapiens	Q15349	Anti Bait CoIP	16810323
Cross	BRAF	P15056	Ksr1	Mus musculus	Q61097	Anti Tag CoIP	22510884
Intra	BRAF	P15056	YWHAZ	Homo sapiens	P63104	Pull Down	15161933
Intra	BRAF	P15056	YWHAZ	Homo sapiens	P63104	Anti Tag CoIP	31980649
Intra	BRAF	P15056	YWHAZ	Homo sapiens	P63104	TAP	17979178
Intra	BRAF	P15056	YWHAZ	Homo sapiens	P63104	Anti Tag CoIP	33961781
Intra	BRAF	P15056	YWHAZ	Homo sapiens	P63104	Pull Down	32707033
Intra	BRAF	P15056	YWHAZ	Homo sapiens	P63104	CoIP	15324660
Intra	BRAF	P15056	YWHAZ	Homo sapiens	P63104	Anti Tag CoIP	28514442
Intra	BRAF	P15056	HRAS	Homo sapiens	P01112	NMR	26165597
Intra	BRAF	P15056	HRAS	Homo sapiens	P01112	GMS	26165597
Intra	BRAF	P15056	HRAS	Homo sapiens	P01112	Anti Tag CoIP	33961781
Intra	BRAF	P15056	HRAS	Homo sapiens	P01112	Anti Tag CoIP	28514442
Intra	BRAF	P15056	HRAS	Homo sapiens	P01112	SLS	26165597
Intra	BRAF	P15056	HSP90AB1	Homo sapiens	P08238	Anti Tag CoIP	31980649
Intra	BRAF	P15056	HSP90AB1	Homo sapiens	P08238	TAP	17979178
Intra	BRAF	P15056	YWHAE	Homo sapiens	P62258	Anti Tag CoIP	31980649
Intra	BRAF	P15056	YWHAE	Homo sapiens	P62258	Pull Down	32707033
Intra	BRAF	P15056	YWHAE	Homo sapiens	P62258	Crosslink	36931259
Intra	BRAF	P15056	YWHAE	Homo sapiens	P62258	Anti Tag CoIP	33961781
Intra	BRAF	P15056	YWHAE	Homo sapiens	P62258	Anti Tag CoIP	28514442
Intra	BRAF	P15056	YWHAE	Homo sapiens	P62258	TAP	17979178
Intra	BRAF	P15056	YWHAB	Homo sapiens	P31946	CoIP	15324660
Intra	BRAF	P15056	YWHAB	Homo sapiens	P31946	Y2H	12620389
Intra	BRAF	P15056	YWHAB	Homo sapiens	P31946	Pull Down	32707033
Intra	BRAF	P15056	YWHAB	Homo sapiens	P31946	Anti Tag CoIP	31980649
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	Anti Tag CoIP	33961781
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	Anti Bait CoIP	25155755
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	Fluorescence	25155755
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	SPR	25155755
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	Pull Down	32707033
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	TAP	17979178
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	SPR	24746704
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	Protein Kinase Assay	25437913
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	Anti Tag CoIP	31980649
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	Anti Tag CoIP	25155755
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	Protein Kinase Assay	25155755
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	GMS	25155755
Intra	BRAF	P15056	MAP2K1	Homo sapiens	Q02750	Kinase HTRF	25155755
Intra	BRAF	P15056	RAF1	Homo sapiens	P04049	Anti Bait CoIP	22169110
Intra	BRAF	P15056	RAF1	Homo sapiens	P04049	Anti Tag CoIP	20130576
Intra	BRAF	P15056	RAF1	Homo sapiens	P04049	Anti Bait CoIP	20141835
Intra	BRAF	P15056	RAF1	Homo sapiens	P04049	Anti Bait CoIP	23680146
Intra	BRAF	P15056	RAF1	Homo sapiens	P04049	Anti Tag CoIP	33961781
Intra	BRAF	P15056	RAF1	Homo sapiens	P04049	Anti Tag CoIP	31980649
Intra	BRAF	P15056	RAF1	Homo sapiens	P04049	Anti Tag CoIP	22169110
Intra	BRAF	P15056	RAF1	Homo sapiens	P04049	Anti Bait CoIP	25155755
Intra	BRAF	P15056	RAF1	Homo sapiens	P04049	Anti Tag CoIP	37045861
Intra	BRAF	P15056	RAF1	Homo sapiens	P04049	Anti Tag CoIP	20141835
Cross	BRAF	P15056	Raf1	Mus musculus	Q99N57	Anti Tag CoIP	22510884
Intra	BRAF	P15056	SFN	Homo sapiens	P31947	Anti Tag CoIP	31980649
Intra	BRAF	P15056	SFN	Homo sapiens	P31947	TAP	15778465
Intra	BRAF	P15056	NRAS	Homo sapiens	P01111	Pull Down	32707033
Cross	BRAF	P15056	Rgs12	Mus musculus	Q8CGE9	Anti Tag CoIP	17380122

Cross: Cross-species interaction Intra: Intraspecies interaction

BRAF Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80036	BRAF Antibody (YA820)	WB, IHC-P, ICC/IF	Human, Mouse, Rat
HY-P80572	BRAF Antibody (YA855)	WB	Human, Mouse, Rat
HY-P80794	Phospho-BRAF (Thr401) Antibody (YA222)	WB, IP	Human, Mouse, Rat
HY-P80794A	Phospho-BRAF (Thr401) Antibody (YA222)(PBS only)	WB, IP	Human, Mouse, Rat
HY-P84105	BRAF Antibody (YA3802)	WB, IHC-P, ICC/IF, ELISA	Human, Mouse
HY-P84105A	BRAF Antibody (YA3802)(PBS only)	WB, IHC-P, ICC/IF, ELISA	Human, Mouse
HY-P84106	BRAF Antibody (YA3803)	WB, IHC-P, FC, ELISA	Human, Mouse, Monkey
HY-P84106A	BRAF Antibody (YA3803)(PBS only)	WB, IHC-P, FC, ELISA	Human, Mouse, Monkey
HY-P85345	BRAF Antibody (YA5037)	WB; IHC-P; IHC-F; IF-Tissue; IP; FC; ICC/IF	Human, Mouse, Rat
HY-P85529	BRAF Antibody (YA5221)	WB	Human, Mouse
HY-P86220	Phospho-BRAF(Thr401) Antibody (YA5912)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Newborn Respiratory Distress Syndrome	Hyaline Membrane Disease Respiratory Distress Syndrome Of Newborn Neonatal Respiratory Distress Hmd - Hyaline Membrane Disease Neonatal Respiratory Distress Syndrome Pulmonary Hyaline Membrane Disease Pulmonary Hypoperfusion Syndrome Of Newborn Respiratory Distress Syndrome, Newborn Respiratory Distress Syndrome Cardiorespiratory Distress Syndrome Of Newborn Distress Respiratory Syndrome Newborn Idiopathic Respiratory Distress Syndrome Idiopathic Respiratory Distress Syndrome Of Newborn Newborn Idiopathic Respiratory Distress Syndrome Respiratory Distress Syndrome In Newborn Rds - [Respiratory Distress Syndrome] Of Newborn Newborn Cardiorespiratory Distress Syndrome
Papillary Carcinoma	Carcinoma, Papillary Carcinoma Papillary
Lip And Oral Cavity Cancer	Oral Cancer Lip And Oral Cavity Carcinoma Malignant Neoplasm Of Mouth
Histiocytic Sarcoma	Malignant Histiocytosis
Gliosarcoma	Glioblastoma With Sarcomatous Component Sarcomatous Glioblastoma
Gastric Adenocarcinoma	Adenocarcinoma Of Stomach Stomach Adenocarcinoma Adenocarcinoma Gastric Intestinal Type Adenocarcinoma Of Unspecified Site Diffuse Type Adenocarcinoma Of Unspecified Site
Cardiomyopathy, Familial Hypertrophic, 4	Hypertrophic Cardiomyopathy 4 CMH4 Cardiomyopathy, Hypertrophic, 4 Cardiomyopathy, Familial Hypertrophic 4 Cardiomyopathy, Familial Hypertrophic, 4, Susceptibility To Cardiomyopathy, Hypertrophic, Familial, Type 4
Ventricular Septal Defect	Ventricular Septal Defects Interventricular Septal Defect Heart Septal Defects, Ventricular Ventricular Septal Abnormality Interventricular Septum Defect Ventricular Septum Defect Vsd - [Ventricular Septum Defect] Congenital Ventricular Septal Defect Single Ventricular Septal Defect
Glioblastoma	Glioblastoma Multiforme Gbm Adult Glioblastoma Multiforme Grade Iv Adult Astrocytic Tumor Primary Glioblastoma Multiforme Spongioblastoma Multiforme Adult Glioblastoma Primary Glioblastoma
Spitz Nevus	Spitz Naevus Spitz Nevi Epithelioid And Spindle Cell Nevus
Plasma Cell Neoplasm	Plasma Cell Dyscrasia Paraproteinemias Plasma Cell Tumour Plasmacytic Tumor Multiple Myeloma Plasmacytoma Plasma Cell Tumours Plasma Cells Dyscrasia
Breast Cancer	Breast Carcinoma Breast Cancer, Familial Malignant Neoplasm Of Breast Male Breast Cancer Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Hairy Cell Leukemia	Hcl-V Hairy Cell Leukemia Variant Hairy Cell Leukaemia Variant Hcl Leukemic Reticuloendotheliosis Leukemic Reticuloendotheliosis Variant Prolymphocytic Variant Of Hcl Prolymphocytic Variant Of Hairy Cell Leukemia Leukemia Hairy Cell Leukemia, Hairy Cell Leukaemic Reticuloendotheliosis Lre - [Leukemic Reticuloendotheliosis] Hairy-Cell Leukaemia, Nos Hcl - [Hairy Cell Leukaemia] Hairy-Cell Leukaemia Without Mention Of Remission
Thyroid Gland Follicular Carcinoma	Follicular Thyroid Carcinoma Follicular Adenocarcinoma Follicular Adenocarcinoma, Well Differentiated Follicular Carcinoma Thyroid Adenocarcinoma Adenocarcinoma, Follicular
Gastrointestinal Stromal Tumor	GIST Gastrointestinal Stromal Tumors Gastrointestinal Stromal Sarcoma Gastrointestinal Stromal Tumor, Familial Gant Gastrointestinal Stromal Tumour Stromal Tumor Of Gastrointestinal Tract Stromal Tumour Of Gastrointestinal Tract Gastrointestinal Stromal Neoplasm Paraganglioma And Gastric Stromal Sarcoma Plexosarcoma
Classic Hairy Cell Leukemia	Hcl-C Leukemic Reticuloendotheliosis Hairy Cell Leukemia
Cholangiocarcinoma	Cholangiocarcinoma, Susceptibility To Extrahepatic Cholangiocarcinoma Intrahepatic Cholangiocarcinoma Chlc Chlc, Susceptibility To Cc Cholangiocarcinoma Of Biliary Tract Cholangiocellular Carcinoma Distal Cholangiocarcinoma Perihilar Cholangiocarcinoma Bile Duct Cancer Cca Adult Primary Cholangiocellular Carcinoma Bile Duct Carcinoma
Verrucous Papilloma
Differentiated Thyroid Carcinoma	Papillary Or Follicular Thyroid Carcinoma Well-Differentiated Thyroid Carcinoma Differentiated Thyroid Gland Carcinoma
Follicular Adenoma	Follicular Adenoma Of The Thyroid Gland Thyroid Follicular Adenoma Adenoma Follicular Follicular Thyroid Adenoma Thyroid Gland Follicular Adenoma
Gastric Cancer	Stomach Cancer Stomach Carcinoma Gastric Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Cerebellar Astrocytoma	Astrocytoma Of Cerebellum
Esophageal Atresia	Tracheoesophageal Fistula Congenital Atresia Of Esophagus Congenital Imperforate Esophagus Imperforate Esophagus Oesophageal Atresia Te Fistula Tef Tracheoesophageal Fistula With Or Without Esophageal Atresia
Squamous Cell Carcinoma, Head And Neck	Squamous Cell Carcinoma Of The Head And Neck HNSCC Head And Neck Squamous Cell Carcinoma Head And Neck Cancer Squamous Cell Carcinoma Of Lip Squamous Cell Carcinoma, Head And Neck, Somatic Carcinoma Of The Head And Neck Squamous Cell Carcinomas Of Head And Neck Scchn Squamous Cell Carcinoma Of The Hypopharynx Squamous Cell Carcinoma Of The Oropharynx Squamous Cell Carcinoma Of Salivary Glands Squamous Cell Carcinoma Of The Nasal Cavity And Paranasal Sinuses Squamous Cell Carcinoma Of The Nasal Cavity And Sinuses Squamous Cell Carcinoma Of The Oral Cavity Squamous Cell Carcinoma Of The Lip Carcinoma, Squamous Cell Of Head And Neck Lip Squamous Cell Carcinoma Cancer, Head/Neck Carcinoma, Squamous Cell, Head And Neck Salivary Gland Squamous Cell Carcinoma Cancer Of Head And Neck Squamous Cell Carcinoma Of Oropharynx Nos
Giant Cell Glioblastoma	Monstrocellular Sarcoma
Brain Stem Glioma	Brainstem Neuroglial Tumor Brainstem Glioma Glioma Of Brainstem
Thyroid Cancer, Nonmedullary, 1	Papillary Thyroid Carcinoma Familial Nonmedullary Thyroid Cancer, Papillary Nonmedullary Thyroid Carcinoma, Papillary NMTC1 Papillary Carcinoma Of Thyroid Pact Thyroid Carcinoma, Papillary Non-Medullary Thyroid Carcinoma Papillary Thyroid Cancer Thyroid Cancer, Non-Medullary, 1 Familial Non-Medullary Thyroid Cancer Fnmtc Nmtc Nonmedullary Thyroid Carcinoma Ptc Tpc Thyroid Papillary Carcinoma Cancer, Thyroid, Nonmedullary Cancer, Thyroid, Nonmedullary, Type 1 Thyroid Carcinoma, Nonmedullary 1 Familial Nonmedullary Thyroid Gland Carcinoma Papillary Carcinoma, Diffuse Sclerosing, Thyroid Gland
Pseudo-Turner Syndrome	Noonan Syndrome
Epididymis Cancer	Malignant Tumor Of Epididymis Malignant Epididymal Tumor Malignant Neoplasm Of Epididymis Neoplasm Of Epididymis
Papillary Thyroid Microcarcinoma
Squamous Cell Carcinoma	Epidermoid Carcinoma Squamous Cell Cancer Carcinoma, Squamous Cell Malignant Squamous Cell Tumor Squamous Carcinoma Squamous Cell Epithelioma Squamous Cell Skin Cancer Carcinoma Squamous Cell Neoplasms, Squamous Cell Squamous Cell Carcinoma - Category Malignant Squamous Cell Neoplasm Squamous Cell Carcinoma Of Skin
Brain Cancer	Malignant Neoplasm Of Brain Adult Brain Tumor Brain Neoplasms Brain Neoplasm Neoplasm Of Brain Primary Malignant Neoplasm Of Brain Brain Tumors Adult Malignant Brain Neoplasm Brain Neoplasm, Adult Bt - Brain Tumour Malignant Brain Tumour Malignant Primary Brain Neoplasm Malignant Primary Brain Tumor Malignant Tumor Of Adult Brain Malignant Tumor Of Brain Primary Brain Neoplasm Primary Brain Tumor Tumor Of The Brain Brain Tumor, Adult Brain Tumor Primary Malignant Primary Brain Tumors Primary Brain Tumors Cancer, Brain Brain Tumor, Primary
Ovarian Serous Cystadenocarcinoma	Serous Cystadenoma Cystadenoma Serous Cystadenoma, Serous
Adrenal Cortical Carcinoma	Adrenocortical Carcinoma Adrenal Cortex Carcinoma Carcinoma Of The Adrenal Cortex Acc Adrenocortical Cancer Carcinoma Adrenocortical
Melanoma	Malignant Melanoma Cutaneous Melanoma Naevocarcinoma Malignant Melanomas
Pulmonic Stenosis	Congenital Pulmonary Valvar Stenosis Congenital Stenosis Of Pulmonary Valve Valvular Pulmonic Stenosis Pulmonary Valve Stenosis Pulmonary Stenosis Congenital Pulmonary Valve Stricture Congenital Pulmonary Valve Stenosis
Juvenile Myelomonocytic Leukemia	Leukemia, Juvenile Myelomonocytic JMML Leukemia, Juvenile Myelomonocytic, Somatic Juvenile Chronic Myelomonocytic Leukemia Juvenile Chronic Myelogenous Leukemia Leukemia, Myelomonocytic, Juvenile Juvenile Myelomonocytic Leukaemia Without Mention Of Remission
Familial Adenomatous Polyposis	Adenomatous Polyposis Coli Fap Familial Multiple Polyposis Syndrome Adenomatous Polyposis Of The Colon Familial Intestinal Polyposis Familial Polyposis Coli Fpc Familial Adenomatous Polyposis Of The Colon Familial Multiple Polyposis Familial Polyposis Of The Colon Hereditary Polyposis Coli Polyposis, Adenomatous Intestinal Adenomatous Familial Polyposis Adenomatous Familial Polyposis Syndrome Myh-Associated Polyposis Colorectal Adenomatous Polyposis Adenomatous Polyposis, Familial Mutyh-Associate Polyposis
Tall Cell Variant Papillary Carcinoma	Tall Cell Variant Thyroid Gland Papillary Carcinoma
Skin Melanoma	Cutaneous Melanoma Malignant Ear Melanoma Malignant Lip Melanoma Malignant Lower Limb Melanoma Malignant Melanoma Of Ear And/Or External Auricular Canal Malignant Melanoma Of Skin Of Lower Limb Malignant Melanoma Of Skin Of Trunk Except Scrotum Malignant Melanoma Of Skin Of Upper Limb Malignant Neck Melanoma Malignant Scalp Melanoma Malignant Trunk Melanoma Malignant Upper Limb Melanoma Melanoma, Cutaneous Malignant Melanoma Malignant Melanoma Of Skin Melanoma Nos Malignant Mole, Meaning Melanoma Of Unspecified Site Melanoma Of Unspecified Site Cutaneous Malignant Melanoma Mm - [Malignant Melanoma]
Colonic Benign Neoplasm	Colon Neoplasm Colonic Mass Colonic Tumor Neoplasm Of Colon Neoplasm Of The Colon Colonic Neoplasms Colon Cancer Colon Carcinoma Nos Colonic Cancer Metastatic Colon Cancer Nos
Erdheim-Chester Disease	Ecd Erdheim Chester Disease Lipoid Granulomatosis Lipid Granulomatosis Polyostotic Sclerosing Histiocytosis
Colitis
Melanoma In Congenital Melanocytic Nevus	Malignant Melanoma In Congenital Melanocytic Nevus Melanocytic Nevi Nevi Melanocytic
Leukemia, Chronic Myeloid	Chronic Myeloid Leukemia Chronic Myelogenous Leukemia CML Chronic Granulocytic Leukemia Leukemia, Philadelphia Chromosome-Positive, Resistant To Imatinib Chronic Myeloid Leukaemia Chronic Granulocytic Leukaemia Chronic Myelogenous Leukaemia Myeloid Leukemia, Chronic Leukemia, Chronic Myelogenous Leukemia, Chronic Myeloid, Philadelphia Chromosome Positive, Somatic Cml - Chronic Myelogenous Leukemia Cgl Chronic Myelocytic Leukemia Leukemia, Chronic Myeloid, Atypical ACML Atypical Chronic Myeloid Leukemia Bcr-Abl1 Negative Myeloid Leukemia Chronic Leukemia, Myeloid, Chronic Leukemia, Myeloid, Chronic, Atypical, Bcr-Abl Negative Cml- [Chronic Myeloid Leukaemia] Cgl - [Chronic Granulocytic Leukaemia] Chronic Myelocytic Leukaemia
Lung Cancer Susceptibility 3	Lung Adenocarcinoma Adenocarcinoma Of Lung LNCR3 Adenocarcinoma Of Lung, Susceptibility To Bronchogenic Lung Adenocarcinoma Nonsmall Cell Adenocarcinoma Adenocarcinoma Lung Lung Adenocarcinomas Non-Small Cell Adenocarcinoma
Acral Lentiginous Melanoma	Acral Lentiginous Melanoma, Malignant Malignant Acral Lentiginous Melanoma Alm Acral Lentiginous Malignant Melanoma Of Skin Palmar/Plantar Melanoma Subungual Melanoma Acral Lentiginous Malignant Melanoma
Nevus Of Ota	Nevus Fusculoceruleus Ophthalmomaxillaris
Nodular Malignant Melanoma	Nodular Melanoma
Renal Cell Carcinoma, Nonpapillary	Renal Cell Carcinoma RCC Nonpapillary Renal Cell Carcinoma Clear Cell Renal Cell Carcinoma Hypernephroma Adenocarcinoma Of Kidney Renal Carcinoma, Chromophobe, Somatic Clear Cell Carcinoma Of Kidney Clear-Cell Metastatic Renal Cell Carcinoma Clear Cell Renal Carcinoma Renal Cell Carcinoma, Somatic Conventional Renal Cell Carcinoma Conventional Renal Cell Carcinoma Renal Clear Cell Carcinoma Ccrcc Hereditary Clear Cell Renal Cell Carcinoma Carcinoma, Renal Cell Renal Cell Carcinoma, Clear Cell, Somatic Renal Cell Carcinoma, Clear Cell Clear Cell Kidney Carcinoma Clear Cell Rcc Cystic-Multilocular Variant Clear Cell Renal Cell Adenocarcinoma Hereditary Clear Cell Renal Cell Adenocarcinoma Common Renal Cell Carcinoma Crcc Renal Cell Carcinoma Non-Papillary Carcinoma Renal Cell Renal Cell Cancer Carcinoma, Renal Cell, Nonpapillary
Ulcerative Colitis	Colitis Gravis Left Sided Ulcerative Colitis Left-Sided Ulcerative Colitis Idiopathic Proctocolitis Inflammatory Bowel Disease, Ulcerative Colitis Type Uc Colitis Ulcerative Colitis, Ulcerative Chronic Left-Sided Ulcerative Colitis Uc - [Ulcerative Colitis] Chronic Ulcerative Enteritis Mucosal Proctocolitis Ulcerative Mucosal Proctocolitis Left Hemicolitis
Pilomyxoid Astrocytoma
Nephrotic Syndrome, Type 3	NPHS3 Nephrotic Syndrome Type 3 Nephrotic Syndrome, Early-Onset, Type 3 Early Onset Nephrotic Syndrome Type 3 Nephrotic Syndrome 3 Early-Onset Nephrotic Syndrome Type 3
Nodular Goiter	Goiter, Nodular Nodular Goitre Goiter Nodular Non-Toxic Nodular Goiter
Craniopharyngioma	Neoplasm Of Rathke'S Pouch Adamantinomatous Tumor Craniopharyngeal Duct Tumor Dysodontogenic Epithelial Tumor Rathke'S Pouch Tumor
Lymphoma	Lymphoid Cancer Lymphomas Lymphoid Cancers Lymphoid Neoplasm Lymphoma Nos Nhl - [Non-Hodgkin Lymphoma] Non-Hodgkin Lymphoma Non-Hodgkin Lymphoma, Nos Non-Hodgkin Malignant Lymphoma Nos
Thyroid Cancer, Nonmedullary, 2	Thyroid Carcinoma, Follicular Follicular Thyroid Carcinoma NMTC2 Thyroid Cancer, Follicular Thyroid Carcinoma, Follicular, Somatic Ftc Thyroid Cancer, Non-Medullary, 2 Thyroid Follicular Carcinoma Follicular Thyroid Cancer Cancer, Thyroid, Nonmedullary, Type 2 Thyroid Gland Adenocarcinoma Follicular Carcinoma Of Unspecified Site Moderately Differentiated Follicular Carcinoma Of Thyroid Gland Pure Follicle Carcinoma Of Thyroid Gland Pure Follicle Follicular Carcinoma Of Unspecified Site Pure Follicular Carcinoma Of Thyroid Gland Trabecular Follicular Carcinoma Of Thyroid Gland Trabecular Follicular Carcinoma Of Unspecified Site Well Differentiated Follicular Carcinoma Of Unspecified Site Well Differentiated Follicular Carcinoma Of Thyroid Gland
Ataxia-Telangiectasia	Ataxia Telangiectasia Louis-Bar Syndrome AT At1 Ataxia-Telangiectasia Syndrome Ataxia - Telangiectasia Variant Boder-Sedgwick Syndrome Louis Bar Syndrome Cerebello-Oculocutaneous Telangiectasia Immunodeficiency With Ataxia Telangiectasia A-T Ataxia Telangiectasia Syndrome Atm Telangiectasia, Cerebello-Oculocutaneous Ataxia-Telangiectasia Variant
Hypothyroidism	Thyroid Diseases Thyroid Deficiency Thyroid Insufficiency Dysfunction Thyroid Thyroid Disease Thyroid Dysfunction
Adenoma	Acinar Cell Adenoma Adenomas Acinic Cell Adenoma
Myeloma, Multiple	Multiple Myeloma Kahler Disease Myelomatosis Plasma Cell Myeloma Medullary Plasmacytoma Multiple Myeloma, Resistance To Myeloma Plasma Cell Dyscrasia Multiple Myeloma, Susceptibility To Myeloma - Multiple Kahler'S Disease Kahler-Bozzolo Disease Plasma Cell Myelomas MM Plasma Cell Neoplasm Primary Systemic Amyloidosis Primary Amyloidosis Immunoglobulin Deposition Disease Plasmacytic Myeloma Multiple Myelomata Multiple Myeloma Nos Multiple Myeloma Without Mention Of Remission Monostotic Plasma Cell Myeloma Mm - [Multiple Myeloma]
Mucosal Melanoma
Pilocytic Astrocytoma Of Cerebellum	Cerebellar Pilocytic Astrocytoma
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Cancer Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Noonan Syndrome With Multiple Lentigines	Leopard Syndrome Multiple Lentigines Syndrome Moynahan Syndrome Cardiomyopathic Lentiginosis Progressive Cardiomyopathic Lentiginosis Cardio-Cutaneous Syndrome Lentiginosis Profusa Capute-Rimoin-Konigsmark-Esterly-Richardson Syndrome Generalized Lentiginosis Gorlin Syndrome Ii Lentiginosis Profusa Syndrome Lentigines, Electrocardiographic Conduction Abnormalities, Ocular Hypertelorism, Pulmonic Stenosis, Abnormal Genitalia, Retardation Of Growth, Deafnes Diffuse Lentiginosis Nsml Familial Multiple Lentigines Syndrome Alopecia-Epilepsy-Intellectual Disability Syndrome, Moynahan Type Progressive Cardiomyopathic Lentiginosis Syndrome Alopecia Epilepsy Oligophrenia Syndrome Of Moynahan
Melanoma, Cutaneous Malignant 1	Familial Melanoma Melanoma, Cutaneous Malignant, Susceptibility To, 1 CMM1 Melanoma, Cutaneous Malignant Cmm Melanoma, Malignant Familial Atypical Mole-Malignant Melanoma Syndrome Fammm Melanoma, Familial Mlm Dysplastic Nevus Syndrome, Hereditary Dns B-K Mole Syndrome Melanoma, Cutaneous Malignant, 1 Malignant Melanoma, Cutaneous Melanoma, Cutaneous, Malignant, Susceptibility To, Type 1 Dysplastic Nevus Syndrome Cutaneous Melanoma Familial Atypical Mole Melanoma Syndrome Hereditary Melanoma
Skin Squamous Cell Carcinoma	Squamous Cell Carcinoma Of Skin Epidermoid Skin Carcinoma Squamous Cell Carcinoma Of The Skin Squamous Cell Epithelioma Of Skin Cutaneous Squamous Cell Carcinoma Scc - [Squamous Cell Carcinoma] Of Skin
Lung Squamous Cell Carcinoma	Squamous Cell Carcinoma Of Lung Squamous Cell Lung Carcinoma Epidermoid Cell Carcinoma Of The Lung Squamous Cell Lung Cancer
Papillary Craniopharyngioma	Craniopharyngioma, Papillary Papillary Rathke'S Pouch Tumor Craniopharyngioma Papillary
Nonseminomatous Germ Cell Tumor	Nsgct Non-Seminomatous Germ-Cell Tumors Germ Cell Tumor, Nonseminomatous
Lymphoma, Non-Hodgkin, Familial	Non-Hodgkin Lymphoma Lymphoma, Non-Hodgkin NHL Lymphoma, Non-Hodgkin, Somatic Lymphoma, Follicular, Somatic Familial Non-Hodgkin Lymphoma Lymphoma Non-Hodgkins Follicular Lymphoma, Somatic Lymphosarcoma Non-Hodgkins Lymphoma
Lynch Syndrome	Hereditary Nonpolyposis Colon Cancer Hereditary Nonpolyposis Colorectal Cancer Hereditary Nonpolyposis Colorectal Carcinoma Hereditary Nonpolyposis Colorectal Neoplasms Familial Nonpolyposis Colon Cancer Hnpcc Coca 1 Hereditary Defective Mismatch Repair Syndrome Hereditary Non-Polyposis Colon Cancer Hereditary Non-Polyposis Colon Cancer Syndrome Hereditary Non-Polyposis Colorectal Cancer Hereditary Non-Polyposis Colorectal Cancer Syndrome Hereditary Nonpolyposis Colon Cancer Syndrome Hereditary Nonpolyposis Colorectal Cancer Syndrome Hereditary Nonpolyposis Colorectal Neoplasm Hnpcc - Hereditary Nonpolyposis Colon Cancer Cancer Family Syndrome Familial Nonpolyposis Colorectal Cancer Colon Cancer, Familial Nonpolyposis Colorectal Neoplasms, Hereditary Nonpolyposis Cancer, Colorectal, Nonpolyposis, Hereditary Colorectal Cancer, Hereditary Nonpolyposis, Type 1
Wilms Tumor 1	Nephroblastoma Wilms Tumor WT1 Wilms' Tumor Bilateral Wilms Tumor Wilms Tumor, Type 1 Wilms Tumor, Somatic Adult Nephroblastoma Wt1 Disorder Renal Embryonic Tumor Adult Kidney Wilms Tumor Childhood Kidney Wilms Tumor Nonanaplastic Kidney Wilms Tumor
Lung Cancer	Lung Carcinoma Non-Small Cell Lung Carcinoma Lung Cancer, Protection Against Lung Cancer, Susceptibility To Adenocarcinoma Of Lung, Somatic Nonsmall Cell Lung Cancer Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In Lung Neoplasm Carcinoma Of Lung Lung Non-Small Cell Carcinoma Non-Small Cell Lung Cancer Nsclc Lung Neoplasms Malignant Neoplasm Of Lung Alveolar Cell Carcinoma Nonsmall Cell Lung Cancer, Somatic Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In Nonsmall Cell Lung Cancer, Susceptibility To Lung Cancer, Somatic Lung Cancer, Resistance To Cancer Of Lung Cancer Of Bronchus Cancer Of The Lung Lung Malignancies Lung Malignant Tumors Malignant Lung Tumor Malignant Tumor Of Lung Pulmonary Cancer Pulmonary Carcinoma Pulmonary Neoplasms Respiratory Carcinoma LNCR Adenocarcinoma Of Lung Neoplasm Of Lung Cancer Lung Carcinoma Non-Small Cell Lung Carcinoma, Non-Small-Cell Lung Lung Cancers Lung Carcinomas Cancer, Lung Cancer, Lung, Non-Small Cell Primary Malignant Neoplasm Of Lung Bronchioloalveolar Adenocarcinoma
Dandy-Walker Syndrome	Dandy-Walker Malformation DWS Atresia Of Foramina Of Magendie And Luschka Dandy-Walker Complex Dandy-Walker Deformity Dandy Walker Cyst Dw Complex Dandy-Walker Syndrome Or Malformation Dandy-Walker Variant Mega Cisterna Magna Dandy-Walker Cyst Dwm Hydrocephalus, Internal, Dandy-Walker Type Hydrocephalus, Noncommunicating, Dandy-Walker Type Luschka-Magendie Foramina Atresia Isolated Dandy-Walker Malformation Mega-Cisterna Magna Dandy Walker Variant Atresia Of Foramen Of Luschka Atresia Of Foramen Of Magendie Congenital Blockage Of Foramen Magendie
Skin Benign Neoplasm	Neoplasm Of Skin By Site Tumor Of The Skin Skin Tumor Benign Neoplasm Of Skin Skin Neoplasms
Melphalan Allergy	Alkeran Allergy
Histiocytosis	Chronic Histiocytosis X Hand Schuller Christian Disease Hand-Schüller-Christian Disease Histiocytic Syndrome Histiocytosis, Langerhans-Cell
Panniculitis	Nodular Panniculitis
Tethered Spinal Cord Syndrome	Spinal Dysraphism Tethered Cord Syndrome Occult Spinal Dysraphism Occult Spinal Dysraphism Sequence Segmental Vertebral Anomalies Tethered Spinal Cord Disease Tethered Cord Spina Bifida Occulta Cryptomerorachischisis Spina Bifida Occulta With Tethered Spinal Cord Sbo - [Spina Bifida Occulta]
Renal Cell Carcinoma, Papillary, 1	Papillary Renal Cell Carcinoma Hereditary Papillary Renal Cell Carcinoma Papillary Renal Cell Carcinoma, Sporadic Papillary Renal Cell Adenocarcinoma RCCP RCCP1 Renal Cell Carcinoma, Papillary Renal Cell Carcinoma, Papillary, 1, Familial And Somatic Chromophil Carcinoma Of Kidney Papillary Kidney Carcinoma Sporadic Papillary Renal Cell Carcinoma Chromophil Renal Cell Carcinoma Papillary Renal Carcinoma, Malignant - Papillary Renal Cell Carcinoma, Bilateral - Papillary Renal Cell Carcinoma, Familial - Papillary Renal Cell Carcinoma, Multiple - Papillary Renal Cell Carcinoma, Sporadic - Renal Adenocarcinoma Chromophil Rcc Hprcc Renal Cell Carcinoma Papillary Chromophilic Renal Cell Carcinoma Prcc Carcinoma, Renal Cell, Papillary, Type 1 Type 1 Papillary Renal Cell Carcinoma Renal Cell Carcinoma Hereditary Papillary Renal Carcinoma
Melanoma, Uveal	Uveal Melanoma Choroidal Melanoma Melanoma Of Uvea Iris Melanoma Malignant Melanoma Of Choroid Malignant Melanoma Of Iris
Leopard Syndrome 3	LPRD3 Noonan Syndrome With Multiple Lentigines 3 Leopard Syndrome, Type 3
Colorectal Cancer, Hereditary Nonpolyposis, Type 5	HNPCC5 Hereditary Nonpolyposis Colorectal Cancer Type 5 Hereditary Non-Polyposis Colorectal Cancer 5 Cancer, Colorectal, Nonpolyposis, Hereditary, Type 5
Arteriovenous Malformation	Arteriovenous Malformations Arteriovenous Hemangioma Cirsoid Aneurysm Racemose Aneurysm Racemose Angioma Racemose Hemangioma Congenital Arteriovenous Malformation
Acneiform Dermatitis	Dermatitis Acneiform
Microphthalmia	Microphthalmos Isolated Anophthalmia-Microphthalmia Syndrome Isolated Microphthalmia-Anophthalmia-Coloboma Simple Microphthalmos Clinical Anophthalmia Isolated Anophthalmia - Microphthalmia Isolated Pure Microphthalmia Mac Spectrum Microphthalmia-Anophthalmia-Coloboma Spectrum Primitive Anophthalmia Globe Of Eye Small Small Eyeball Hypoplasia Of Eye Isolated Nanophthalmos Rudimentary Eye Dysplasia Of Eye
Wilms Tumor 5	Wilms Tumor WT5 Wilms Tumor Susceptibility-5 Wilms Tumor And Radial Bilateral Aplasia Nephroblastoma Wilms' Tumor Wilms Tumor, Susceptibility To Wtsl Bilateral Radial Aplasia With Wilms Tumor Embryonal Adenosarcoma Embryonal Nephroma Kidney Wilms Tumor Kidney, Adenomyosarcoma, Embryonal Kidney, Carcinosarcoma, Embryonal Kidney, Embryoma Kidney, Embryonal Mixed Tumor Nephroma Renal Adenosarcoma Renal Cancer, Wilms Renal Wilms Tumor Tumor, Wilms Hereditary Susceptibility To Wilms Tumor 5
Bladder Urothelial Carcinoma	Bladder Transitional Cell Carcinoma Transitional Cell Carcinoma Of Bladder Transitional Cell Carcinoma Of The Bladder Urinary Bladder Urothelial Carcinoma Urothelial Bladder Carcinoma Carcinoma Transitional Cell Bladder Tcc - [Transitional Cell Carcinoma] Of Bladder
Adenocarcinoma	Adenocarcinomas Adenoacanthoma Of Unspecified Site Adenocarcinoid Of Unspecified Site Adenocarcinoid Tumour Of Unspecified Site Adenocarcinoma And Carcinoid Combined Of Unspecified Site Adenocarcinoma Nos
Parotid Gland Adenoid Cystic Carcinoma	Adenoid Cystic Carcinoma Of Parotid Gland
Epididymis Adenocarcinoma	Adenocarcinoma Of The Epididymis
Langerhans Cell Histiocytosis	Histiocytosis X Lch Langerhans Cell Granulomatosis Langerhans-Cell Histiocytosis Letterer-Siwe Disease Hashimoto-Pritzger Disease Histiocytosis, Langerhans-Cell Langerhan'S Cell Histiocytosis Letterer-Siwe Disease Involving Intra-Abdominal Lymph Nodes Letterer-Siwe Disease Involving Intrapelvic Lymph Nodes Letterer-Siwe Disease Involving Intrathoracic Lymph Nodes Letterer-Siwe Disease Involving Lymph Nodes Of Axilla And Upper Limb Letterer-Siwe Disease Involving Lymph Nodes Of Head, Face And Neck Letterer-Siwe Disease Involving Lymph Nodes Of Head, Face, And Neck Letterer-Siwe Disease Involving Lymph Nodes Of Inguinal Region And Lower Limb Letterer-Siwe Disease Involving Lymph Nodes Of Multiple Sites Letterer-Siwe Disease Involving Spleen Letterer-Siwe Disease Of Intra-Abdominal Lymph Nodes Letterer-Siwe Disease Of Intrapelvic Lymph Nodes Letterer-Siwe Disease Of Intrathoracic Lymph Nodes Letterer-Siwe Disease Of Lymph Nodes Of Axilla And Upper Limb Letterer-Siwe Disease Of Lymph Nodes Of Axilla And/Or Upper Limb Letterer-Siwe Disease Of Lymph Nodes Of Head, Face And Neck Letterer-Siwe Disease Of Lymph Nodes Of Head, Face And/Or Neck Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region Amd/Or Lower Limb Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region And Lower Limb Letterer-Siwe Disease Of Lymph Nodes Of Inguinal Region And/Or Lower Limb Letterer-Siwe Disease Of Lymph Nodes Of Multiple Sites Letterer-Siwe Disease Of Spleen Familial Letterer-Siwe Disease Langerhans-Cell Histiocytosis Nos
Thyroid Gland Anaplastic Carcinoma	Anaplastic Thyroid Carcinoma Anaplastic Thyroid Cancer Thyroid Cancer, Anaplastic Thyroid Carcinoma, Anaplastic Thyroid Carcinoma Anaplastic
Phace Association	Phace Syndrome Phaces Association Supraumbilical Midabdominal Raphe And Facial Cavernous Hemangiomas Pascual-Castroviejo Syndrome Type 2 Aortic Aneurysm, Giant Congenital P-Ciis Pascual-Castroviejo Type Ii Syndrome Posterior Fossa Brain Malformations, Hemangiomas Of The Face, Arterial Anomalies, Cardiac Anomalies, And Eye Abnormalities Hemangiomas Cavernous Of Face Supraumbilical Midline Raphe Raphe, Supraumbilical Midline, With Cavernous Facial Hemangiomas Sternal Nonunion With Supraumbilical Raphe Phaces Syndrome
Pilocytic Astrocytoma	Juvenile Pilocytic Astrocytoma Grade I Astrocytic Tumor Piloid Astrocytoma
Arteriovenous Malformations Of The Brain	Cerebral Arteriovenous Malformation Intracranial Arteriovenous Malformation Intracranial Hemorrhage In Brain Cerebrovascular Malformations, Susceptibility To Intracranial Arteriovenous Malformations Bavm Cerebral Arteriovenous Malformations Intracranial Hemorrhage In Brain Cerebrovascular Malformations Arteriovenous Malformation Of The Brain, Somatic Intracranial Avm Arteriovenous Malformations Cerebral
Childhood Astrocytic Tumor	Juvenile Astrocytoma Pediatric Astrocytoma
Cardiofaciocutaneous Syndrome 1	Cardiofaciocutaneous Syndrome Cfc Syndrome Cardio-Facio-Cutaneous Syndrome CFC1 Cfcs Cardio-Facial-Cutaneous Syndrome Congenital Heart Defects Characteristic Facial Appearance Ectodermal Abnormalities And Growth Failure Cardiofaciocutaneous Syndrome, Type 1
Rasopathy	Ras/Mitogen-Activated Protein Kinase Syndrome
Urethra Transitional Cell Carcinoma	Urethral Transitional Cell Carcinoma Urethral Urothelial Carcinoma
Pancreatic Adenocarcinoma	Adenocarcinoma Of Pancreas Adenocarcinoma Of The Pancreas Pancreas Adenocarcinoma Malignant Exocrine Neoplasm Primary Pancreatic Adenocarcinoma Adenocarcinoma Of Islet Cell Of Pancreas Islet Cell Adenocarcinoma Of Unspecified Site Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site
Lentigines	Lentigo
Spherocytosis, Type 5	Hereditary Spherocytosis Type 5 SPH5 Hs5 Spherocytosis, Hereditary, 5 Hereditary Spherocytosis 5 Spherocytosis 5 Spherocytosis, Hereditary, Type 5
Leukemia	Leukemias Leukaemia, Unspecified, Without Mention Of Remission Aleukemic Leukaemia Chronic Leukaemia Subacute Leukaemia Leukaemia Disorder Leukaemia Nos
Hashimoto Thyroiditis	Autoimmune Thyroiditis Hashimoto Struma Hashimoto'S Thyroiditis Chronic Lymphocytic Thyroiditis Lymphocytic Thyroiditis Hashimoto Disease Ht Hashimoto'S Disease Hashimoto'S Syndrome Hypothyroidism, Autoimmune Autoimmune Chronic Lymphocytic Thyroiditis Chronic Lymphocytic Thyroiditides Hashimoto Syndrome Hashimotos Thyroiditis Hashimoto Thyroiditis, Susceptibility To Thyroiditis, Autoimmune Lymphomatous Thyroiditis Lymphoid Thyroiditis Chronic Lymphadenoid Thyroiditis Autoimmune Lymphocytic Chronic Thyroiditis Goitre Lymphomatosa Hashitoxicosis Hashimoto Hypothyroidism Lymphadenoid Goitre Struma Lymphomatosa Hyperthyroidism With Hashimoto Disease Hashimoto Thyrotoxicosis Thyrotoxicosis Due To Hashimoto Thyroiditis Struma Lymphomatosis Lymphadenoid Struma
Non-Langerhans-Cell Histiocytosis	Histiocytosis, Non-Langerhans-Cell Non-Langerhans Cell Histiocytosis
Noonan Syndrome 7	NS7 Noonan Syndrome, Type 7
Suppression Of Tumorigenicity 12	Prostate Adenocarcinoma Adenocarcinoma Of Prostate ST12 Prostate Adenocarcinoma 1 Pac1
Lymphangioma	Lymphatic Malformation Lymphatic Malformations Benign Lymphangioma Congenital Lymphangioma Lymphangiomas
Gallbladder Cancer	Gallbladder Carcinoma Gallbladder Neoplasm Malignant Neoplasm Of Gallbladder Malignant Tumour Of Gallbladder Gallbladder Ca Localized Malignant Gallbladder Neoplasm Malignant Tumor Of The Gallbladder Tumor Of The Gallbladder Cancer Of The Gallbladder Carcinoma Gallbladder Carcinoma Of Gallbladder Gallbladder Neoplasms Malignant Neoplasm Of Gallbladder Localized Cancer Of Gallbladder Primary Malignant Neoplasm Of Gallbladder
Hypertrophic Cardiomyopathy	Hypertrophic Obstructive Cardiomyopathy Cardiomyopathy, Hypertrophic Cardiomyopathy, Hypertrophic, Familial Familial Hypertrophic Cardiomyopathy Cardiomyopathy Hypertrophic Obstructive Idiopathic Myocardial Hypertrophy Idiopathic Hypertrophic Cardiomyopathy Obstructive Idiopathic Hypertrophic Cardiomyopathy Obstructive Cardiomyopathy Idiopathic Hypertrophic Subaortic Stenosis Muscular Subaortic Stenosis Hypertrophic Obstructive Subaortic Stenosis
Thyroid Carcinoma, Familial Medullary	Medullary Thyroid Carcinoma Familial Medullary Thyroid Carcinoma MTC Fmtc Mtc1 Thyroid Cancer, Medullary Medullary Thyroid Cancer Thyroid Carcinoma, Medullary Familial Mtc Thyroid Carcinoma Medullary Carcinoma, Thyroid, Medullary, Familial Medullary Carcinoma Of Thyroid Medullary Carcinoma With Amyloid Stroma, Unspecified Site Medullary Carcinoma With Amyloid Stroma Of Thyroid
Bladder Cancer	Urinary Bladder Cancer Bladder Carcinoma Urinary Bladder Carcinoma Bladder Neoplasm Bladder Tumor Cancer, Bladder Malignant Neoplasm Of Urinary Bladder Carcinoma Of Bladder Bladder Cancer, Somatic Tumor Of The Bladder Carcinoma Of Urinary Bladder Bladder Carcinoma Urinary Cancer Of The Urinary Bladder Cancer, Urinary Bladder Malignant Bladder Neoplasm Malignant Bladder Tumor Neoplasm Of The Bladder Neoplasm Of The Urinary Bladder Tumor Of The Urinary Bladder Urinary Bladder Neoplasm BLC Urothelial Carcinoma Of The Bladder Bladder Tumors Urinary Bladder Neoplasms Bladder Cancer Nos Vesical Cancer Nos Malignant Neoplasm Of Bladder, Part Unspecified Malignant Tumour Of Urinary Bladder Primary Malignant Neoplasm Of Bladder
Clear Cell Sarcoma	Sarcoma, Clear Cell Adult Soft Part Clear Cell Sarcoma Clear Cell Sarcoma Of Soft Parts Malignant Melanoma Of Soft Parts Malignant Melanoma Of Soft Tissues Melanoma, Malignant, Of Soft Parts Sarcoma Clear Cell
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Chronic Myelogenous Leukemia, Bcr-Abl1 Positive	Chronic Myelogenous Leukemia, Bcr/Abl Positive Chronic Myelosis Chronic Myeloid Leukaemia, Bcr-Abl-Positive Without Mention Of Remission
Syringocystadenoma Papilliferum	Fistulous Vegetative Verrucous Hydradenoma Papillary Syringadenoma Naevus Syringocystadenomatosus Papilliferus Papillary Syringocystadenoma Scap Syringadenoma Papilliferum Papillary Hidradenoma
Noonan Syndrome And Noonan-Related Syndrome
Adenofibroma
Struma Ovarii
Pleomorphic Xanthoastrocytoma	Pxa Pleomorphic Xantho-Astrocytoma
Costello Syndrome	Faciocutaneoskeletal Syndrome Fcs Syndrome Congenital Myopathy With Excess Of Muscle Spindles CSTLO CMEMS Fcss Myopathy, Congenital, With Excess Of Muscle Spindles
Thyroid Tumor
Childhood Pilocytic Astrocytoma	Pediatric Pilocytic Astrocytoma
Noonan Syndrome 1	Noonan Syndrome NS1 Male Turner Syndrome Female Pseudo-Turner Syndrome Turner Phenotype With Normal Karyotype Noonan Syndrome With Pigmented Villonodular Synovitis Turner'S Phenotype, Karyotype Normal Familial Turner Syndrome Noonan'S Syndrome Noonan-Ehmke Syndrome Ns Pseudo-Ullrich-Turner Syndrome Turner Syndrome In Female With X Chromosome Turner-Like Syndrome Ullrich-Noonan Syndrome Noonan-Like/Multiple Giant Cell Lesion Syndrome Noonan Syndrome-Like Disorder With Multiple Giant Cell Lesions Pterygium Colli Syndrome Noonan Syndrome, Type 1 Turner Syndrome, Male
Sarcoma	Connective And Soft Tissue Neoplasm Tumor Of Soft Tissue And Skeleton Sarcomas Sarcoma - Category
Ganglioglioma	Childhood Ganglioglioma Adult Ganglioglioma Cns Ganglioglioma Mixed Cell Tumors Containing Both Neural Ganglionic Cells And Neural Glial Cell Components
Oligodendroglioma	Oligodendroglial Neoplasm Oligodendroglial Tumor Oligodendroglial Tumors Well Differentiated Oligodendroglioma
Thyroid Gland Cancer	Thyroid Gland Carcinoma Malignant Neoplasm Of Thyroid Gland Malignant Tumour Of Thyroid Gland Thyroid Neoplasm Thyroid Neoplasms Neoplasm Of Thyroid Gland Thyroid Gland Neoplasm Head And Neck Cancer, Thyroid Neoplasm Of The Thyroid Gland Cancer Of The Thyroid Primary Malignant Neoplasm Of Thyroglossal Duct Malignant Neoplasm Of Thyroglossal Duct Primary Malignant Neoplasm Of Thyroid Gland Thyroglossal Duct Cancer Toxic Goitre Malignant Tumour Cancerous Goitre
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Colon Adenocarcinoma	Adenocarcinoma Of Colon Adenocarcinoma Of The Colon Colonic Adenocarcinoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (9)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-10201	Sorafenib		99.85%	Yes
HY-14660	Dabrafenib		99.94%	Yes
HY-12057	Vemurafenib		99.90%	Yes
HY-15605	Encorafenib	Inhibitor	99.94%	Yes
HY-18652	Avutometinib	Inhibitor	99.43%	Unkown
HY-10201A	Sorafenib tosylate		99.98%	Yes
HY-10201S	Sorafenib-d3		99.57%	Unkown
HY-10201R	Sorafenib (Standard)		99.71%	Unkown
HY-10201AR	Sorafenib tosylate (Standard)		/	Unkown

Clinical Phase

Bioactive Molecules (22)

Cat. No.	Product Name	Effect	Purity	Phase
HY-148439	Daraxonrasib	Inhibitor	99.96%	Phase 3
HY-112089	Naporafenib	Inhibitor	99.92%	Phase 3
HY-132844	Tunlametinib	Inhibitor	99.53%	Phase 3
HY-10320	Doramapimod	Inhibitor	99.98%	Phase 2
HY-18972	Plixorafenib	Inhibitor	99.80%	Phase 2
HY-109080	Belvarafenib	Inhibitor	98.97%	Phase 2
HY-114491	Rineterkib	Inhibitor	98.79%	Phase 2
HY-111940	LUT014		97.09%	Phase 2
HY-114491A	Rineterkib hydrochloride	Inhibitor	99.81%	Phase 2
HY-109080A	Belvarafenib TFA	Inhibitor	≥99.0%	Phase 2
HY-158115	NST-628	Inhibitor	99.35%	Phase 1
HY-51424	PLX-4720	Inhibitor	99.90%	Phase 1
HY-12558	LY3009120		98.66%	Phase 1
HY-15200	Agerafenib	Inhibitor	99.78%	Phase 1
HY-153341	Tagarafdeg	Degrader	99.41%	Phase 1
HY-15610	GDC-0623		98.74%	Phase 1
HY-18957	Lifirafenib	Inhibitor	98.01%	Phase 1
HY-159795	Claturafenib	Inhibitor	99.95%	Phase 1
HY-147405	Tinlorafenib	Inhibitor	98.21%	Phase 1
HY-15199	Agerafenib hydrochloride	Inhibitor	/	Phase 1
HY-18957B	Lifirafenib maleate	Inhibitor	/	Phase 1
HY-19343	XL-281	Inhibitor	/	Phase 1

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P991507	SCT200	Inhibitor	99.09%	Phase 2

Pre-clinical Phase

Bioactive Molecules (147)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-50846	SCH772984	Inhibitor	99.83%	Unkown
HY-10966	SB-590885	Inhibitor	99.77%	Unkown
HY-101494	Temuterkib	Inhibitor	99.93%	Unkown
HY-12661A	AMG PERK 44		99.67%	Unkown
HY-50864	GDC-0879	Inhibitor	99.49%	Unkown
HY-147268	Exarafenib	Inhibitor	99.68%	Unkown
HY-11004	AZ 628		99.44%	Unkown
HY-18832	AWL-II-38.3	Inhibitor	99.68%	Unkown
HY-136420	SJF-0628		99.90%	Unkown
HY-15767	TAK-632	Inhibitor	98.93%	Unkown
HY-W074340	tert-Butyl 5-aminopentanoate		/	Unkown
HY-Y1322	Triphenyl phosphate		99.67%	Unkown
HY-137487	PROTAC BRAF-V600E degrader-1	Degrader	98.04%	Unkown
HY-14177	Raf inhibitor 1	Inhibitor	98.03%	Unkown
HY-202699	SHOC2-RAS PPI-IN-1	Inhibitor	99.50%	Unkown
HY-17598	Rafoxanide		98.60%	Unkown
HY-155736	MAPK-IN-2	Inhibitor	99.66%	Unkown
HY-181067	IK-595	Inhibitor	98.55%	Unkown
HY-145120	Mosperafenib	Inhibitor	98.29%	Unkown
HY-111758	PROTAC B-Raf degrader 1	Inhibitor	99.78%	Unkown
HY-N9330	Broussoflavonol F		98.11%	Unkown
HY-12846	CCT196969	Inhibitor	99.67%	Unkown
HY-100510	RAF709	Inhibitor	99.92%	Unkown
HY-18997	PLX7904	Inhibitor	98.72%	Unkown
HY-10247	BRAF inhibitor	Inhibitor	98.07%	Unkown
HY-136567	TBAP-001	Inhibitor	98.97%	Unkown
HY-12787	L-779450		98.75%	Unkown
HY-107779	BI-882370	Inhibitor	98.55%	Unkown
HY-77113	B-Raf IN 11	Inhibitor	99.46%	Unkown
HY-12291	HG6-64-1		99.32%	Unkown
HY-149464	ARN22089	Inhibitor	98.18%	Unkown
HY-P10438	TAT-Braftide	Inhibitor	99.52%	Unkown
HY-107415	PLX7922	Inhibitor	98.68%	Unkown
HY-P10436	Braftide	Inhibitor	99.51%	Unkown
HY-148059	Uplarafenib	Inhibitor	99.63%	Unkown
HY-18227	B-Raf IN 1	Inhibitor	99.94%	Unkown
HY-18507	AD57	Inhibitor	98.27%	Unkown
HY-10201S2	Sorafenib-13C,d3		98.35%	Unkown
HY-117658	GSK-114	Inhibitor	99.52%	Unkown
HY-153603	B-Raf IN 15	Inhibitor	98.0%	Unkown
HY-142160	GNE-9815	Inhibitor	98.94%	Unkown
HY-12847	CCT241161		99.77%	Unkown
HY-144269	SHR902275	Inhibitor	99.80%	Unkown
HY-149380	Vem-L-Cy5	Inhibitor	98.31%	Unkown
HY-P11706	MS1 peptide		/	Unkown
HY-15605S	Encorafenib-13C,d3	Inhibitor	98.14%	Unkown
HY-RS01588	BRAF Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-117273	AZ304	Inhibitor	99.77%	Unkown
HY-130617	Pomalidomide-amido-C1-Br		/	Unkown
HY-150639	Everafenib	Inhibitor	/	Unkown
HY-15198	KG5	Inhibitor	99.79%	Unkown
HY-164474	DS03090629	Inhibitor	99.16%	Unkown
HY-179505	OPN-9652	Inhibitor	98.84%	Unkown
HY-10966R	SB-590885 (Standard)	Inhibitor	99.55%	Unkown
HY-164524	SBI-0640726	Inhibitor	/	Unkown
HY-10201S1	Sorafenib-d4		99.9%	Unkown
HY-108887	Anticancer agent 124	Inhibitor	/	Unkown
HY-11043	PF-0419789	Inhibitor	/	Unkown
HY-126298	RAF mutant-IN-1	Inhibitor	/	Unkown
HY-44237	Pomalidomide-CO-C-NH2		/	Unkown
HY-10201S4	Sorafenib-d3 tosylate	Inhibitor	/	Unkown
HY-103086	INU-152	Inhibitor	/	Unkown
HY-10966G	SB-590885 (GMP)	Inhibitor	/	Unkown
HY-115933	EGFR/BRAF-IN-1	Inhibitor	/	Unkown
HY-117707	EBI-907	Inhibitor	/	Unkown
HY-12057S	Vemurafenib-d5		/	Unkown
HY-12057S1	Vemurafenib-d7		/	Unkown
HY-123799	SB-699393	Inhibitor	/	Unkown
HY-126180	BAY-866	Inhibitor	/	Unkown
HY-135216	Antiproliferative agent-54	Inhibitor	/	Unkown
HY-137488	PROTAC BRAF-V600E degrader-2	Inhibitor	/	Unkown
HY-13810	PF-04880594	Inhibitor	/	Unkown
HY-142820	B-Raf IN 5	Inhibitor	/	Unkown
HY-142830	B-Raf IN 6	Inhibitor	/	Unkown
HY-144271	RAF-IN-1	Inhibitor	/	Unkown
HY-146442	BRAF V600E/CRAF-IN-1	Inhibitor	/	Unkown
HY-146443	BRAF V600E/CRAF-IN-2	Inhibitor	/	Unkown
HY-146491	VEGFR-2/BRAF-IN-1		/	Unkown
HY-146492	VEGFR-2/BRAF-IN-2		/	Unkown
HY-147825	EGFR/BRAFV600E-IN-1		/	Unkown
HY-147852	B-Raf IN 7	Inhibitor	/	Unkown
HY-147853	B-Raf IN 8	Inhibitor	/	Unkown
HY-147854	B-Raf IN 9		/	Unkown
HY-149415	Multi-kinase-IN-5	Inhibitor	/	Unkown
HY-149517	EGFR/BRAFV600E-IN-2		/	Unkown
HY-14979	ML786	Inhibitor	/	Unkown
HY-14979A	ML786 dihydrochloride	Inhibitor	/	Unkown
HY-150250	B-Raf IN 13	Inhibitor	/	Unkown
HY-153914	B-Raf IN 14	Inhibitor	/	Unkown
HY-155942	B-Raf IN 19	Inhibitor	/	Unkown
HY-156554	Raf inhibitor 3	Inhibitor	/	Unkown
HY-156590	B-Raf IN 16	Inhibitor	/	Unkown
HY-158027	B-Raf IN 17	Inhibitor	/	Unkown
HY-16063	ARQ-736	Inhibitor	/	Unkown
HY-162460	ERK1/2 inhibitor 10	Inhibitor	/	Unkown
HY-162873	MEK/RAF-IN-1	Inhibitor	/	Unkown
HY-164400	SIJ1777		/	Unkown
HY-164428	AE 51310	Inhibitor	/	Unkown
HY-164492	LSN3074753	Inhibitor	/	Unkown
HY-168013	KRASG12C IN-14	Inhibitor	/	Unkown
HY-168125	JNK-IN-18	Inhibitor	/	Unkown
HY-168442	KRAS inhibitor-40	Inhibitor	/	Unkown
HY-168512	BRAFV600E-IN-1	Inhibitor	/	Unkown
HY-169869	pan-Raf/RTK inhibitor 1	Inhibitor	/	Unkown
HY-173164	EGFR/BRAFV600E-IN-4		/	Unkown
HY-174274	ERK2-IN-6	Inhibitor	/	Unkown
HY-175435	CST905	Degrader	/	Unkown
HY-175726	BRAF ligand-Linker Conjugate 1		/	Unkown
HY-175831	BRAFV600E-IN-2	Inhibitor	/	Unkown
HY-17598R	Rafoxanide (Standard)		/	Unkown
HY-178995	BRAFV600E-IN-3	Inhibitor	/	Unkown
HY-179012	CDC20/HSP90-IN-1		/	Unkown
HY-179098	Multi-target kinase-IN-8		/	Unkown
HY-179559	OPN-9643	Inhibitor	/	Unkown
HY-180154	EGFR/BRAFV600E-IN-6		/	Unkown
HY-180161	B-Raf-IN-20	Inhibitor	/	Unkown
HY-180419	SF-3-030		/	Unkown
HY-181061	COX/5-LO-IN-2		/	Unkown
HY-181130	Anticancer agent 299		/	Unkown
HY-181131	Anticancer agent 300		/	Unkown
HY-181913	KRAS G12C-IN-76	Inhibitor	/	Unkown
HY-181978	GIT1-IN-1		/	Unkown
HY-182763	EGFR/BRAFV600E-IN-7		/	Unkown
HY-18318	Takeda-6D	Inhibitor	99.41%	Unkown
HY-183674	MEK-IN-10		/	Unkown
HY-184447	RN193	Inhibitor	/	Unkown
HY-184546	BRAFV600E ligand-1	Ligand	/	Unkown
HY-184581	Pomalidomide-5-C4-acid		/	Unkown
HY-184599	OICR-403184	Inhibitor	/	Unkown
HY-18507A	AD57 hydrochloride	Inhibitor	/	Unkown
HY-18652A	Avutometinib potassium	Inhibitor	/	Unkown
HY-187012	BRAF ligand-2	Ligand	/	Unkown
HY-E70649	BRAF V600E Recombinant Human Active Protein Kinase		/	Unkown
HY-N13841	2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose		/	Unkown
HY-RS01589	Braf Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS01590	Braf Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-120676	B-Raf IN 18	Inhibitor	/	Unkown
HY-14177A	Raf inhibitor 1 dihydrochloride	Inhibitor	99.29%	Unkown
HY-164529	SJ-C1044	Inhibitor	98.63%	Unkown
HY-164530	SKLB646	Inhibitor	/	Unkown
HY-177946	RAF-IN-4	Inhibitor	/	Unkown
HY-180329	CG 858-Neg		/	Unkown
HY-184875	B-Raf-IN-21	Inhibitor	/	Unkown
HY-186223	Enzyme modulator-1	Modulator	/	Unkown
HY-18817	AFG210	Inhibitor	/	Unkown
HY-41747	BRAF ligand-1	Ligand	/	Unkown
HY-51424S	PLX-4720-d7	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	BRAF	RGD	RGD:619908
Felis catus	BRAF	VGNC	VGNC:60162
Bos taurus	BRAF	VGNC	VGNC:26551
Mus musculus	BRAF	MGD	MGI:88190
Canis familiaris	BRAF	VGNC	VGNC:38514
Others	BRAF	NCBI