NAV1 - Nav1 neuron navigator 1 Gene
Species: Rattus norvegicus
Gene Type: protein coding
Gene ID: 685707
Summary
Predicted to be involved in microtubule bundle formation and neuron migration. Predicted to be active in axon initial segment and microtubule Cytoskeleton. Orthologous to human NAV1 (neuron navigator 1). [provided by Alliance of Genome Resources, Apr 2022]
NAV1 Products (9)
| mRNA | Protein | Name |
|---|---|---|
| XM_006249898.4 | XP_006249960.1 | neuron navigator 1 isoform X4 |
| XM_039091323.1 | XP_038947251.1 | neuron navigator 1 isoform X7 |
| XM_039091322.1 | XP_038947250.1 | neuron navigator 1 isoform X6 |
| XM_039091321.1 | XP_038947249.1 | neuron navigator 1 isoform X5 |
| XM_039091320.1 | XP_038947248.1 | neuron navigator 1 isoform X3 |
| XM_039091319.1 | XP_038947247.1 | neuron navigator 1 isoform X2 |
| XM_039091318.1 | XP_038947246.1 | neuron navigator 1 isoform X1 |
| XM_039091325.1 | XP_038947253.1 | neuron navigator 1 isoform X9 |
| XM_039091324.1 | XP_038947252.1 | neuron navigator 1 isoform X8 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
neuron navigator 1 |
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(6)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-148800 | Suzetrigine | Inhibitor | 99.98% | Unkown |
| HY-17429 | Flecainide acetate | Inhibitor | 99.35% | Unkown |
| HY-17355A | Dexpramipexole dihydrochloride | 99.94% | Yes | |
| HY-B0262 | Methocarbamol | Inhibitor | 99.68% | Unkown |
| HY-17355B | Dexpramipexole | 99.56% | Yes | |
| HY-17355AR | Dexpramipexole dihydrochloride (Standard) | / | Unkown |
Clinical Phase
Bioactive Molecules
(20)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-148410A | Zorevunersen sodium | Activator | 99.27% | Phase 3 |
| HY-105285 | Piromelatine | 99.70% | Phase 3 | |
| HY-148410 | Zorevunersen | Activator | 98.50% | Phase 3 |
| HY-12883 | PF 05089771 | Inhibitor | 99.87% | Phase 2 |
| HY-147423 | Zandatrigine | Inhibitor | 99.28% | Phase 2 |
| HY-12796A | Raxatrigine hydrochloride | Inhibitor | 99.10% | Phase 2 |
| HY-12796 | Raxatrigine | Inhibitor | 99.85% | Phase 2 |
| HY-16723 | Funapide | Inhibitor | 99.83% | Phase 2 |
| HY-131182 | DS-1971a | Inhibitor | 99.30% | Phase 2 |
| HY-105283 | PF 04531083 | Antagonist | 99.62% | Phase 2 |
| HY-125079 | DSP-2230 | Inhibitor | 98.33% | Phase 1 |
| HY-114237 | GDC-0276 | Inhibitor | 99.69% | Phase 1 |
| HY-139081 | GDC-0310 | Inhibitor | 98.84% | Phase 1 |
| HY-103623 | PF-05241328 | Inhibitor | 98.08% | Phase 1 |
| HY-114301 | PF-06305591 | Inhibitor | 99.74% | Phase 1 |
| HY-101383 | PF-01247324 | Inhibitor | 99.77% | Phase 1 |
| HY-122001 | PF-05186462 | Inhibitor | 99.69% | Phase 1 |
| HY-114301A | PF-06305591 dihydrate | Inhibitor | 99.84% | Phase 1 |
| HY-128794 | PF-05150122 | / | Phase 1 | |
| HY-W040555 | Norquetiapine dihydrochloride | 99.91% | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(172)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-N6691 | Veratridine | Inhibitor | 99.42% | Unkown |
| HY-100001 | SKF-96365 (hydrochloride) | 99.93% | Unkown | |
| HY-11079 | A-803467 | Inhibitor | 99.69% | Unkown |
| HY-100345 | AMTB hydrochloride | Inhibitor | 99.08% | Unkown |
| HY-16787 | ICA-121431 | Inhibitor | 99.35% | Unkown |
| HY-12811 | PF-04856264 | Inhibitor | 99.29% | Unkown |
| HY-118952A | PF-06456384 trihydrochloride | Inhibitor | 99.38% | Unkown |
| HY-P1221A | ProTx II TFA | Inhibitor | 99.86% | Unkown |
| HY-107405 | TC-N 1752 | Inhibitor | 99.67% | Unkown |
| HY-157802 | LTGO-33 | Inhibitor | 98.83% | Unkown |
| HY-126429 | Nav1.1 activator 1 | Activator | 98.98% | Unkown |
| HY-B0824 | Bifenthrin | Activator | 99.76% | Yes |
| HY-148792 | Relutrigine | Inhibitor | 99.33% | Unkown |
| HY-157786 | XPC-5462 | Inhibitor | 99.65% | Unkown |
| HY-100727 | AM-2099 | Inhibitor | 98.37% | Unkown |
| HY-164795A | SBI-810 hydrochloride | 99.55% | Unkown | |
| HY-W052508 | Norquetiapine | 99.95% | Unkown | |
| HY-157784 | XPC-7724 | Inhibitor | 99.46% | Unkown |
| HY-133012 | GFB-8438 | Inhibitor | 99.74% | Unkown |
| HY-171244 | Sodium Channel inhibitor 6 | Inhibitor | 99.93% | Unkown |
| HY-110325 | PF-04885614 | Inhibitor | 97.00% | Unkown |
| HY-B1837 | Cyfluthrin | Inhibitor | 99.52% | Unkown |
| HY-P10234A | Poneratoxin acetate | Modulator | 98.35% | Unkown |
| HY-19958 | XEN907 | Inhibitor | 98.74% | Unkown |
| HY-139346 | VX-150 | Inhibitor | 98.36% | Unkown |
| HY-133910 | Lu AE98134 | Activator | 98.07% | Unkown |
| HY-13985 | Nav1.7 inhibitor | Inhibitor | 99.63% | Unkown |
| HY-112279 | GNE-131 | Inhibitor | 98.15% | Unkown |
| HY-131870 | GX-201 | Inhibitor | 98.46% | Unkown |
| HY-145169 | AZ194 | Inhibitor | 99.45% | Unkown |
| HY-152166 | NaV1.2/1.6 channel blocker-1 | Inhibitor | / | Unkown |
| HY-125928 | AA43279 | Inhibitor | 99.80% | Unkown |
| HY-101789 | Nav1.7-IN-3 | Inhibitor | 98.21% | Unkown |
| HY-123824 | GNE-0439 | Inhibitor | 99.80% | Unkown |
| HY-155635 | Nav1.8-IN-4 | Inhibitor | 99.78% | Unkown |
| HY-20362 | 4-Azaindole | 99.57% | Unkown | |
| HY-N0478 | Neoline | 98.0% | Unkown | |
| HY-N1847 | 3'-Methoxydaidzein | Inhibitor | 99.67% | Unkown |
| HY-128772 | XPC-6444 | Inhibitor | 98.93 | Unkown |
| HY-157802A | (S)-LTGO-33 | Inhibitor | 99.41% | Unkown |
| HY-P1220A | Huwentoxin-IV TFA | Inhibitor | 99.18% | Unkown |
| HY-119934 | NaV1.7 inhibitor-1 | Inhibitor | 99.17% | Unkown |
| HY-123825 | GX-674 | Antagonist | 98.45% | Unkown |
| HY-143481 | Nav1.8-IN-2 | Inhibitor | 99.83% | Unkown |
| HY-P1218B | Phrixotoxin 3-NH2 TFA | Inhibitor | 98.96% | Unkown |
| HY-148410C | Zorevunensen negative control | Activator | 99.28% | Unkown |
| HY-12883A | PF-05198007 | Inhibitor | 99.27% | Unkown |
| HY-146069 | ABBV-318 | Inhibitor | 98.72% | Unkown |
| HY-125942 | SKF-96365 | 99.97% | Unkown | |
| HY-156596 | Aneratrigine | Inhibitor | 99.60% | Unkown |
| HY-178281 | E0199 | 99.89% | Unkown | |
| HY-P5807A | Cn2 toxin TFA | Agonist | 96.59% | Unkown |
| HY-155058 | Nav1.3 channel inhibitor 1 | Inhibitor | 99.11% | Unkown |
| HY-164795 | SBI-810 | 98.25% | Unkown | |
| HY-178494 | Nav1.7-IN-19 | Inhibitor | 98.87% | Unkown |
| HY-P1073 | ProTx-I | Inhibitor | 95.15% | Unkown |
| HY-P1441A | Mambalgin 1 TFA | Inhibitor | 95.72% | Unkown |
| HY-P1681A | GpTx-1 TFA | Antagonist | 99.56% | Unkown |
| HY-18689 | SYM2206 | Antagonist | 99.83% | Unkown |
| HY-108425B | (Rac)-AMG8379 | Antagonist | 99.25% | Unkown |
| HY-16723A | (R)-Funapide | Inhibitor | 99.22% | Unkown |
| HY-123414 | GX-936 | Inhibitor | 97.06% | Unkown |
| HY-15736 | Sodium Channel inhibitor 1 | Inhibitor | 99.38% | Unkown |
| HY-158979 | Nav1.8-IN-14 | Inhibitor | 99.83% | Unkown |
| HY-160591 | Nav1.8-IN-10 | Inhibitor | / | Unkown |
| HY-160593 | Nav1.8-IN-12 | Inhibitor | / | Unkown |
| HY-163855 | KGP-25 | Inhibitor | 95.0% | Unkown |
| HY-172903 | Nav1.8-IN-16 | Inhibitor | / | Unkown |
| HY-172933 | Nav1.8 modulator 1 | Modulator | / | Unkown |
| HY-17429S | Flecainide-d4 acetate | Inhibitor | 99.0% | Unkown |
| HY-176911 | Nav1.8-IN-21 | Inhibitor | / | Unkown |
| HY-19366 | Nav1.7-IN-2 | Inhibitor | 98.28% | Unkown |
| HY-P1221 | ProTx II | Inhibitor | 98.34% | Unkown |
| HY-P1443 | OD1 | Modulator | 99.40% | Unkown |
| HY-P5160A | Phlotoxin-1 TFA | Inhibitor | 92.73% | Unkown |
| HY-P5786 | Heteropodatoxin-1 | / | Unkown | |
| HY-RS09046 | NAV1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-123833 | PF-05661014 | Modulator | 99.56% | Unkown |
| HY-102998 | Nav1.7-IN-6 | Inhibitor | / | Unkown |
| HY-108425 | AMG8379 | Antagonist | / | Unkown |
| HY-126291 | GNE-616 | Inhibitor | / | Unkown |
| HY-183566 | MK-5661 | Inhibitor | / | Unkown |
| HY-W052508S | Norquetiapine-d8 | / | Unkown | |
| HY-108425A | AMG8380 | Inhibitor | / | Unkown |
| HY-116137 | Nav1.7-IN-17 | / | Unkown | |
| HY-117714 | AZD-3161 | Inhibitor | / | Unkown |
| HY-118952 | PF-06456384 | Inhibitor | / | Unkown |
| HY-120774 | GS-462808 | Inhibitor | / | Unkown |
| HY-126005 | VGSC blocker-1 | Inhibitor | / | Unkown |
| HY-12883B | PF 05089771 tosylate | Inhibitor | / | Unkown |
| HY-132133 | Nav1.8-IN-1 | Inhibitor | / | Unkown |
| HY-135495 | AM-0466 | Inhibitor | / | Unkown |
| HY-138816 | Nav1.7-IN-15 | Antagonist | / | Unkown |
| HY-141547 | Nav1.7-IN-8 | Inhibitor | / | Unkown |
| HY-149944 | Analgesic agent-2 | Inhibitor | / | Unkown |
| HY-149994 | DS43260857 | Inhibitor | / | Unkown |
| HY-155236 | Ancistrotecine B | Inhibitor | / | Unkown |
| HY-159094 | Nav1.8-IN-15 | Inhibitor | / | Unkown |
| HY-160588 | Nav1.8-IN-7 | Inhibitor | / | Unkown |
| HY-160589 | Nav1.8-IN-8 | Inhibitor | / | Unkown |
| HY-160592 | Nav1.8-IN-11 | Inhibitor | / | Unkown |
| HY-160663 | Nav1.7 blocker 1 | / | Unkown | |
| HY-161272 | Nav1.8-IN-6 | Inhibitor | / | Unkown |
| HY-161572 | Nav1.8-IN-13 | Inhibitor | / | Unkown |
| HY-162246 | Nav1.8-IN-5 | Inhibitor | / | Unkown |
| HY-162347 | Nav1.7-IN-13 | Inhibitor | / | Unkown |
| HY-162757 | Anticonvulsant agent 5 | Modulator | / | Unkown |
| HY-167852 | GX-585 | Inhibitor | / | Unkown |
| HY-169421 | Nav1.7-IN-18 | Inhibitor | / | Unkown |
| HY-170930 | Anticonvulsant agent 9 | / | Unkown | |
| HY-171778 | QLS-81 | Inhibitor | / | Unkown |
| HY-172998 | Nav1.8-IN-18 | Inhibitor | / | Unkown |
| HY-172999 | Nav1.8-IN-19 | Inhibitor | / | Unkown |
| HY-174845 | Nav1.8-IN-20 | Inhibitor | / | Unkown |
| HY-175289 | hERG-IN-3 | Inhibitor | / | Unkown |
| HY-176065 | Nav1.2-IN-1 | Inhibitor | / | Unkown |
| HY-178344 | Multi-target kinase-IN-6 | Activator | / | Unkown |
| HY-178963 | Nav1.2-IN-2 | Inhibitor | 99.82% | Unkown |
| HY-179445 | Nav1.7-IN-20 | Inhibitor | / | Unkown |
| HY-181063 | Nav1.5-IN-1 | Inhibitor | / | Unkown |
| HY-181615 | Nav1.8-IN-22 | Inhibitor | / | Unkown |
| HY-182334 | azo-Q2a | Inhibitor | / | Unkown |
| HY-182710 | DA-0218 | Inhibitor | / | Unkown |
| HY-182831 | Nav1.7-IN-22 | Inhibitor | / | Unkown |
| HY-183646 | Nav1.8-IN-23 | Inhibitor | / | Unkown |
| HY-183709 | Nav1.8-IN-24 | Inhibitor | / | Unkown |
| HY-184190 | ERG-IN-7 | Inhibitor | / | Unkown |
| HY-185333 | Sodium Channel-IN-7 | Inhibitor | / | Unkown |
| HY-B0262S | Methocarbamol-d5 | Inhibitor | / | Unkown |
| HY-B0262S2 | Methocarbamol-13C,d3 | Inhibitor | / | Unkown |
| HY-B1837S | Cyfluthrin-d6 | Inhibitor | / | Unkown |
| HY-P10234 | Poneratoxin | Modulator | / | Unkown |
| HY-P11045 | JNJ63955918 | Inhibitor | / | Unkown |
| HY-P1218 | Phrixotoxin 3 | Inhibitor | / | Unkown |
| HY-P1218A | Phrixotoxin 3 TFA | Inhibitor | / | Unkown |
| HY-P1219 | Jingzhaotoxin-III | Inhibitor | / | Unkown |
| HY-P1220 | Huwentoxin-IV | Inhibitor | / | Unkown |
| HY-P1681 | GpTx-1 | Antagonist | / | Unkown |
| HY-P5152 | Scorpion toxin Tf2 | Activator | / | Unkown |
| HY-P5153 | ProTx-III | Inhibitor | / | Unkown |
| HY-P5160 | Phlotoxin-1 | Inhibitor | / | Unkown |
| HY-P5164 | GrTx1 | Inhibitor | / | Unkown |
| HY-P5177 | GsAF-II | Inhibitor | / | Unkown |
| HY-P5781 | δ-Theraphotoxin-Hm1b | Inhibitor | / | Unkown |
| HY-P5782 | δ-Theraphotoxin-Hm1a toxin | Activator | / | Unkown |
| HY-P5783 | δ-Buthitoxin-Hj2a | Agonist | / | Unkown |
| HY-P5784 | δ-Buthitoxin-Hj1a | Agonist | / | Unkown |
| HY-P5790 | μ-TRTX-Hd1a | Inhibitor | / | Unkown |
| HY-P5793 | GTx1-15 | Inhibitor | / | Unkown |
| HY-P5795 | GsAF-I | Inhibitor | / | Unkown |
| HY-P5800 | Phlo1b | Inhibitor | / | Unkown |
| HY-P5801 | Phlo1a | Inhibitor | / | Unkown |
| HY-P5807 | Cn2 toxin | Activator | / | Unkown |
| HY-P5809 | Pe1b | Inhibitor | / | Unkown |
| HY-P5810 | Ceratotoxin-2 | Inhibitor | / | Unkown |
| HY-P5811 | Ceratotoxin-1 | Inhibitor | / | Unkown |
| HY-P5813 | Cd1a | Inhibitor | / | Unkown |
| HY-P5865 | Tap1a | Inhibitor | / | Unkown |
| HY-P5872 | Jingzhaotoxin XI | Inhibitor | / | Unkown |
| HY-P5900 | m3-Huwentoxin IV | Inhibitor | / | Unkown |
| HY-P5916 | VSTx-3 | Antagonist | / | Unkown |
| HY-W031620 | VGSCs-IN-1 | Inhibitor | 99.92% | Unkown |
| HY-W040171 | Tefluthrin | Activator | / | Unkown |
| HY-W699451 | MTSET chloride | Inhibitor | / | Unkown |
| HY-116194 | NaV1.7 blocker-801 | Inhibitor | / | Unkown |
| HY-118048 | NAV 26 | Inhibitor | 99.79% | Unkown |
| HY-17355BS | Dexpramipexole-d3 dihydrochloride | / | Unkown | |
| HY-175226 | DPP8/9-IN-2 | Inhibitor | / | Unkown |
| HY-182195 | Suzetrigine N-oxide | Inhibitor | / | Unkown |
| HY-185334 | GNE-3565 | Inhibitor | / | Unkown |
| HY-185335 | Sodium Channel-IN-8 | Inhibitor | / | Unkown |
| HY-B0262S1 | Methocarbamol-d3 | Inhibitor | 98.15% | Unkown |
Bioactive MoleculesInhibitory Antibodies
(2)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P990503 | Anti-SCN9a/Nav1.7 Antibody | Inhibitor | 98.57% | Unkown |
| HY-P990502 | Anti-SCN11a/Nav1.9 Antibody | Inhibitor | / | Unkown |
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