CAPS - calcyphosine Gene

Also Known as CAPS1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 828

About CAPS

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:5,914,254-5,916,211 (from NCBI)

This gene has 5 transcripts (splice variants), 98 orthologues and 5 paralogues. Broad expression in lung (RPKM 22.4), endometrium (RPKM 13.8) and 21 other tissues.

Summary

This gene encodes a calcium-binding protein, which may play a role in the regulation of ion transport. A similar protein was first described as a potentially important regulatory protein in the dog thyroid and was termed as R2D5 antigen in rabbit. Alternative splicing of this gene generates two transcript variants. [provided by RefSeq, Jul 2008]

CAPS Products (2)

mRNA Protein Name
NM_004058.5 NP_004049.3 calcyphosin isoform a
NM_080590.4 NP_542157.3 calcyphosin isoform b

CAPS Protein Structure

EF-hand_7

EF-hand_7: EF-hand domain pair (26 - 85)

EF-hand_7

EF-hand_7: EF-hand domain pair (100 - 166)

  • 0
  • 100
  • 189 a.a.
Protein Preferred Names Protein Names

calcyphosin

  • calcyphosine 1

Related Diseases

Diseases Alias
Clonorchiasis

  • Oriental Liver Fluke Disease

  • Clonorchis Liver Infection

  • Clonorchiosis

  • Chinese Liver Fluke Disease

  • Hepatic Distomiasis Due To Clonorchis Sinensis

  • Infection Due To Clonorchis Sinensis

  • Hepatic Distomiasis

  • Hepatic Distomatosis

  • Chinese Liver Fluke Disorder

  • Oriental Liver Fluke Disorder

  • Clonorchis Infestation

  • Chinese Liver Fluke Infestation

  • Liver Fluke Disease Due To Clonorchis Sinensis

  • Oriental Liver Fluke Infestation
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-109025 Baloxavir marboxil Inhibitor 99.96% Unkown
HY-109025A Baloxavir Inhibitor 99.92% Unkown
HY-A0148A Halofantrine hydrochloride Inhibitor 99.90% Yes
HY-17452A Cefditoren Pivoxil Inhibitor 99.29% Unkown
HY-109025R Baloxavir marboxil (Standard) Inhibitor 99.90% Unkown
HY-14956 Nemonoxacin Inhibitor 99.77% Unkown
HY-17452 Cefditoren sodium Inhibitor 99.70% Unkown
HY-116229 Gemifloxacin Inhibitor / Unkown
HY-A0148 Halofantrine Inhibitor / Unkown
HY-17452AR Cefditoren Pivoxil (Standard) Inhibitor / Unkown
HY-A0148AR Halofantrine hydrochloride (Standard) Inhibitor / Unkown

Clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Phase
HY-145586A Onradivir monohydrate Inhibitor / Phase 3
HY-143744 Suraxavir marboxil Inhibitor / Phase 3
HY-139553 Zunsemetinib Inhibitor 99.99% Phase 2
HY-P0277 Carcinoembryonic antigen peptide 1 Inducer 99.69% Phase 2
HY-105172 TT-232 Agonist 98.72% Phase 2
HY-12914 V116517 Antagonist / Phase 2
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P991900 LY3541860 Inhibitor ≥99.0% Phase 2
HY-P991224 CAP-100 Inhibitor 99.84% Phase 1

Pre-clinical Phase

Bioactive Molecules (237)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-N0086 N6-Methyladenosine Inhibitor 99.84% Unkown
HY-154831 C22-Ceramide (d18:1/22:0) 99.89% Unkown
HY-145974A m7GpppAmpG ammonium solution (100 mM) 99.96% Unkown
HY-153040 HPPE Inhibitor 99.71% Unkown
HY-15523 Braco-19 Inhibitor 98.01% Unkown
HY-14427 4E1RCat Inhibitor 99.04% Unkown
HY-122524 7-Methylguanosine Inhibitor 99.10% Unkown
HY-162543 18:1 Liss Rhod PE 99% Unkown
HY-139100B m7G(5')ppp(5')A diammonium 99.15% Unkown
HY-145586 Onradivir Inhibitor 99.53% Unkown
HY-79096 Boc-L-phenylalanine 99.84% Unkown
HY-21586B 7-Methyl-guanosine-5'-triphosphate sodium 92.36% Unkown
HY-D0869 CAPS 99.95% Unkown
HY-W141394 Bz-OMe-rA 99.34% Unkown
HY-15523A Braco-19 trihydrochloride Inhibitor 99.57% Unkown
HY-N0086S N6-Methyladenosine-d3 Inhibitor 99.97% Unkown
HY-N2362 DL-Alanine 98.0% Unkown
HY-174497 eGFP mRNA 94.4% Unkown
HY-156048 Trifluoromethyl-tubercidin Inhibitor 99.90% Unkown
HY-139101A Guanosine 5'-triphosphate-5'-adenosine triammonium 99.96% Unkown
HY-153108 3'-O-Me-m7G(5')ppp(5')A solution (100 mM) Chemical 99.38% Unkown
HY-130544 5-Azidopentanoic acid 99.77% Unkown
HY-145969A β-S-ARCA triammonium 99.48% Unkown
HY-109659 1-(3-Aminopropyl)-4-methylpiperazine 99.07% Unkown
HY-145973A 3'OMe-m7GpppAmpG ammonium solution (100 mM) Inhibitor 98.24% Unkown
HY-141472 7-Methylguanosine 5'-diphosphate sodium 97.10% Unkown
HY-156597 Arbemnifosbuvir Inhibitor 99.40% Unkown
HY-18684 SIBA Inhibitor 99.64% Unkown
HY-107823 Cholesteryl acetate 99.21% Unkown
HY-135517 RXP470.1 Inhibitor 99.60% Unkown
HY-145975A m7Gpppm6AmpG ammonium solution (100 mM) 98.26% Unkown
HY-158772 m7G(5')ppp(5')(2'OMeA)pU ammonium solution (100 mM) 99.6% Unkown
HY-178674A Im-m7GDP sodium 89.15% Unkown
HY-N6772 Cytochalasin E Inhibitor 99.90% Unkown
HY-133887 Methotrexate α-tert-butyl ester Inhibitor 97.38% Unkown
HY-122524AR 7-Methylguanosine iodide (Standard) Inhibitor 98.50% Unkown
HY-W028714 2,3-Diphenylquinoxaline-6-carboxylic acid 99.95% Unkown
HY-164927 Tivoxavir marboxil Inhibitor 99.55% Unkown
HY-D0948 Celestine Blue 66.00% Unkown
HY-E70080 Vaccinia virus capping enzyme / Unkown
HY-W996116 AZM198 Inhibitor 98.40% Unkown
HY-140678 mPEG10000-amine 99.87% Unkown
HY-132894 Pixavir marboxil Inhibitor 99.53% Unkown
HY-164188 m7(3'Ma-Cy5)Gppp(2'OMe)ApG triammonium 98% Unkown
HY-164190 m7(3'Ma-Biotin)Gppp(2'OMe)ApG ammonium solution (25mM) 90.00% Unkown
HY-177555 AV5116 Inhibitor 99.57% Unkown
HY-E70081 mRNA Cap 2'-O-methyltransferase / Unkown
HY-145977A m7GpppGmpG ammonium solution (100 mM) 95.07% Unkown
HY-N2362S2 DL-Alanine-d3 98.0% Unkown
HY-139100 N7-Methyl-guanosine-5'-triphosphate-5'-adenosine / Unkown
HY-145538 2'-Deoxyguanosine 5'-monophosphate disodium hydrate 99.0% Unkown
HY-145969 β-S-ARCA / Unkown
HY-159855 CAP 2 hydrochloride 97.6% Unkown
HY-170524 TDI-015051 Inhibitor / Unkown
HY-N2362S DL-Alanine-13C-1 98.0% Unkown
HY-N2362S1 DL-Alanine-13C-3 98.0% Unkown
HY-RS01823 CADPS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-100079 9-Propenyladenine 96.69% Unkown
HY-113897 Chloramphenicol 3-acetate 99.9% Unkown
HY-139098A 7-Methyl-diguanosine triphosphate ammonium solution (100 mM) 98.83% Unkown
HY-145913A m7GpppApG triammonium solution (100 mM) 99.28% Unkown
HY-160957 Cap A (Acetonitrile/Acetic Anhydride, 80/20 v/v) 99.97% Unkown
HY-160958 Cap B Acetonitrile/N-methylimidazole /pyridine, 50/20/30 v/v/v / Unkown
HY-164192A m7(3'AcmG)(5')ppp(5')(2'OMeA)pG trisodium solution (100 mM) 98.61% Unkown
HY-178672 ARCA / Unkown
HY-178672A ARCA triammonium solution (100 mM) / Unkown
HY-N0086S2 N6-Methyladenosine-13C4 Inhibitor 99.8% Unkown
HY-W751835 Baloxavir-d4 99.27% Unkown
HY-109025AS2 Baloxavir-d1 Inhibitor / Unkown
HY-100079R 9-Propenyladenine (Standard) / Unkown
HY-105172A TT-232 TFA Agonist / Unkown
HY-109025AS Baloxavir-d5 Inhibitor / Unkown
HY-109025S2 Baloxavir marboxil-d1 Inhibitor / Unkown
HY-122524AS 7-Methylguanosine-13C,d3 iodide / Unkown
HY-122524AS1 7-Methylguanosine-13C iodide / Unkown
HY-123702 CAP-53194 / Unkown
HY-131736 3'-O-Bn-GTP / Unkown
HY-134809A Cyclotriazadisulfonamide hydrochloride Inhibitor / Unkown
HY-139553A (R)-Zunsemetinib Control 97.57% Unkown
HY-143743 Cap-dependent endonuclease-IN-2 / Unkown
HY-143747 Cap-dependent endonuclease-IN-5 / Unkown
HY-143749 Cap-dependent endonuclease-IN-6 Inhibitor / Unkown
HY-143750 Cap-dependent endonuclease-IN-7 / Unkown
HY-143752 Cap-dependent endonuclease-IN-8 / Unkown
HY-143755 Cap-dependent endonuclease-IN-9 / Unkown
HY-143757 Cap-dependent endonuclease-IN-10 / Unkown
HY-143762 Cap-dependent endonuclease-IN-12 Inhibitor / Unkown
HY-143766 Cap-dependent endonuclease-IN-13 / Unkown
HY-143768 Cap-dependent endonuclease-IN-14 / Unkown
HY-143769 Sebaloxavir marboxil / Unkown
HY-143770 Cap-dependent endonuclease-IN-16 / Unkown
HY-143771 Cap-dependent endonuclease-IN-17 Inhibitor / Unkown
HY-143775 Cap-dependent endonuclease-IN-20 Inhibitor / Unkown
HY-143776 Cap-dependent endonuclease-IN-22 Inhibitor / Unkown
HY-143781 Cap-dependent endonuclease-IN-26 Inhibitor / Unkown
HY-144065 Cap-dependent endonuclease-IN-19 / Unkown
HY-144066 Cap-dependent endonuclease-IN-21 / Unkown
HY-144067 Cap-dependent endonuclease-IN-23 / Unkown
HY-144068 Cap-dependent endonuclease-IN-25 / Unkown
HY-145502 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) sodium 99.48% Unkown
HY-145973 3'OMe-m7GpppAmpG Inhibitor / Unkown
HY-145973AGL 3'OMe-m7GpppAmpG ammonium solution (100 mM) (GMP Like) Inhibitor / Unkown
HY-145973B 3'OMe-m7GpppAmpG Tris Inhibitor / Unkown
HY-145974AGL m7GpppAmpG ammonium solution (100 mM) (GMP like) / Unkown
HY-145975 m7Gpppm6AmpG / Unkown
HY-145977 m7GpppGmpG / Unkown
HY-145979 m7GpppUmpG / Unkown
HY-145980 m7GpppUpG / Unkown
HY-145981 m7GpppCpG / Unkown
HY-145982 m7GpppCmpG / Unkown
HY-147339 M7G (3'-OMe-5') pppA (2'-OMe) / Unkown
HY-147730 HDAC6-IN-8 / Unkown
HY-148664 eIF4E-IN-4 Inhibitor / Unkown
HY-149263 HAA-09 Inhibitor / Unkown
HY-150144 Uracil-m7GpppAmpG ammonium solution (100 mM) Modulator / Unkown
HY-153570 Influenza virus-IN-7 Inhibitor / Unkown
HY-155337 eIF4E-IN-6 Inhibitor / Unkown
HY-155676 eIF4E-IN-5 Inhibitor / Unkown
HY-157339 MMT-2'-O-Methyl adenosine (n-bz) CED phosphoramidite / Unkown
HY-158819 m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG trisodium / Unkown
HY-162242 Cap-dependent endonuclease-IN-27 Inhibitor / Unkown
HY-163498 NLRP3-IN-37 Inhibitor / Unkown
HY-163621 Cap-dependent endonuclease-IN-28 Inhibitor / Unkown
HY-164189 m7(3'Ma-Cy3)Gppp(2'OMe)ApG ammonium / Unkown
HY-164191 m7(3'Ma-Peg5-FAM)Gppp(2'OMe)ApG ammonium / Unkown
HY-164193 m7(3'AcmG)(5')ppp(5')(2'OMeA)pU ammonium / Unkown
HY-170523 RU-0415529 Inhibitor / Unkown
HY-176278 mPEG1000-LA / Unkown
HY-176278A mPEG2000-LA / Unkown
HY-176278B mPEG3400-LA / Unkown
HY-176278C mPEG5000-LA / Unkown
HY-178045 MYC-IN-4 Inhibitor / Unkown
HY-178145 Mc-Lys(PEG12)-Cap-Ala-Ala-PABC-exatecan Inhibitor / Unkown
HY-178146 Mc-Lys(PEG12)-Cap-Ala-Ala-PABC / Unkown
HY-178673S m7G(5')ppp(5')(2'OMeA)-d3 ammonium / Unkown
HY-179556 SARS-CoV-2 nsp14-IN-10 / Unkown
HY-179761 16:0 C4-BODIPY 505/515 DNP Cap PE ammonium / Unkown
HY-181495 RAJQ14 Degrader / Unkown
HY-181498 RAFKBP12 / Unkown
HY-181499 RA190-PEG1-NH2 Ligand / Unkown
HY-181521 RAPRMT5 / Unkown
HY-181523 RA183 Ligand / Unkown
HY-181524 RA183-CO-C6-NHCO-NH-Boc Ligand / Unkown
HY-185601 m7(3'-OMeG)(5')vppp(5')(2'-OMe, m6A)pU triammonium / Unkown
HY-185603 m7G(LNA)(5')ppp(5')(2'OMe, m6A)pG trisodium / Unkown
HY-185609 m7G(2'F)(5')ppp(5')(2'OMeA)pG triammonium / Unkown
HY-185611 A(5')ppp(5')(2'-OMeA)pG tetraammonium / Unkown
HY-185612 m7G(5')vppp(5')(2'-OMeA)pU triammonium / Unkown
HY-185613 m7G(UNA)(5')ppp(5')(2'OMeA)pG triammonium / Unkown
HY-185614 m7(3'OMeG)(5')ppp(5')A ammonium / Unkown
HY-185615 m7G(HNA)(5')ppp(5')(2'OMeA)pG triammonium / Unkown
HY-185617 m7(3'OMeG-LNA)(5')ppp(5')(2'OMe,m6A)pG trisodium / Unkown
HY-185765 MC-PEG4-β-Glu-Baloxavir Inhibitor / Unkown
HY-187368 (S)-DMP2 Inhibitor / Unkown
HY-189094 DcpS-IN-1 / Unkown
HY-21586 7-Methyl-guanosine-5'-triphosphate disodium / Unkown
HY-79096S BOC-L-Phenylalanine-13C / Unkown
HY-79096S2 BOC-L-phenylalanine-d8 / Unkown
HY-D0869S 3-(Cyclohexylamino)-1-propanesulfonic Acid-d17 / Unkown
HY-E70405 Guanylyltransferase / Unkown
HY-N0086S3 N6-Methyladenosine-13C3 Inhibitor / Unkown
HY-N15772 16:0 Folate cap PE disodium / Unkown
HY-N15882 16:0 DNP Cap PE monoammonium / Unkown
HY-N2362S5 DL-Alanine-15N / Unkown
HY-N2362S7 DL-Alanine-13C3-4 / Unkown
HY-P12212 Chondrocyte-affinity peptide / Unkown
HY-P12350 Ac-I3K-NH2 / Unkown
HY-P2458 CAP18 (rabbit) Inhibitor / Unkown
HY-P3911 CAP 37 (20-44) / Unkown
HY-RS01880 CAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01881 CAP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01899 CAPS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01900 CAPS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W1143084A m7G(5')ppp(5' )(2'OMeG) ammonium / Unkown
HY-W340832 18:1 Biotinyl Cap PE 99% Unkown
HY-W423489 SARS-CoV-2-IN-76 Inhibitor / Unkown
HY-115693 CAP 3 Inhibitor / Unkown
HY-122524A 7-Methylguanosine iodide Inhibitor / Unkown
HY-131736A 3'-O-Bn-GTP sodium / Unkown
HY-139098 7-Methyl-diguanosine triphosphate / Unkown
HY-139101 Guanosine 5'-triphosphate-5'-adenosine / Unkown
HY-145913 m7GpppApG / Unkown
HY-145974 m7GpppAmpG / Unkown
HY-145976 m7GpppGpG / Unkown
HY-145976A m7GpppGpG ammonium solution (10 mM) / Unkown
HY-151829 Fmoc-L-Asn(EDA-N3)-OH / Unkown
HY-155927 DMPE-PEG1000 ammonium 99.91% Unkown
HY-157504 2′-O-Methyl-5′-O-phosphonoadenylyl-(3′→5′)-guanosine TEA / Unkown
HY-158819B m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG tetraammonium solution (100 mM) 99.18% Unkown
HY-164187 m7(3'Ma-Cy7)Gppp(2'OMe)ApG ammonium / Unkown
HY-164192 m7(3'AcmG)(5')ppp(5')(2'OMeA)pG ammonium / Unkown
HY-164984 m3227G(5)ppp(5')A / Unkown
HY-164984A m3227G(5)ppp(5')A triammonium / Unkown
HY-164985 m3227G(5)ppp(5')Am / Unkown
HY-164985A m3227G(5)ppp(5')Am triammonium / Unkown
HY-164986 m3227G(5)ppp(5')m6Am / Unkown
HY-164986A m3227G(5)ppp(5')m6Am triammonium / Unkown
HY-171729 Cap-dependent endonuclease-IN-29 Inhibitor / Unkown
HY-173172 MG-002 / Unkown
HY-17452AS Cefditoren pivoxil-d3 Inhibitor / Unkown
HY-17452B Cefditoren Pivoxil hydrochloride Inhibitor / Unkown
HY-174791 Cre-T2A-GFP mRNA (N1-Methylpseudo-UTP) / Unkown
HY-174792 Cre-T2A-GFP mRNA / Unkown
HY-178561 CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG / Unkown
HY-178574 CAP m7(3'-OMeG)(5')vppp(5')(2'-OMeA)pU / Unkown
HY-178602 CAP m7G(5')ppp(5')(2'OMeG) / Unkown
HY-178640 CAP m7G(LNA)(5')ppp(5')A(LNA)pG / Unkown
HY-178671 CAP GAU m7G(5')ppp(5')(2'OMeA)pU / Unkown
HY-178674 Im-m7GDP / Unkown
HY-179048 MH44 Inhibitor / Unkown
HY-180162 Influenza A virus-IN-17 Inhibitor / Unkown
HY-181500 AP1867-NH-PEG3-acid Ligand / Unkown
HY-182162 5'-Pyrene cap phosphoramidite / Unkown
HY-182177 5'-Trimethoxystilbene cap phosphoramidite / Unkown
HY-182962 7-Methylguanosine 5-disphosphoimidazolide disodium / Unkown
HY-183592 Anti-virus agent 2 Inhibitor / Unkown
HY-184263 CHVB-032 Inhibitor / Unkown
HY-184264 CHVB-066 Inhibitor / Unkown
HY-184606 PEI stabilized gold nanoclusters / Unkown
HY-185602 m7G(5')vppp(5')(2'OMeA)pG triammonium / Unkown
HY-187464 MBXC-4522 Inhibitor / Unkown
HY-21586A m7GTP / Unkown
HY-79096S1 BOC-L-phenylalanine-d5 / Unkown
HY-N2362S8 DL-Alanine-d7 / Unkown
HY-N2362S9 DL-Alanine-13C2,15N / Unkown
HY-N7647 Methyl brevifolincarboxylate Inhibitor / Unkown
HY-RS17580 Cap2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17877 Cap1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23265 Caps Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24040 Cap2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24346 Cap1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W102681 Caps sodium salt / Unkown
HY-W112199 9-Anthracenamine / Unkown
HY-W129441 N-Acetyl-4-S-cysteaminylphenol / Unkown
HY-W591314 M-PEG11-Ms / Unkown
HY-W740028 Cefditoren-d3 sodium Inhibitor / Unkown
HY-W975617 4',5,7,8-Tetrahydroxyflavanone Activator 96.25% Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CAPS RGD RGD:41237504
Canis familiaris CAPS VGNC VGNC:54265
Macaca mulatta CAPS VGNC VGNC:108145
Bos taurus CAPS VGNC VGNC:26753
Others CAPS NCBI