ALK - ALK receptor tyrosine kinase Gene
Species: Macaca mulatta
Gene Type: protein coding
Gene ID: 704823
About ALK
Primary_assembly 13: 78,995,892-79,753,056 forward strand.Mmul_10:CM014348.1
This gene has 1 transcript (splice variant), 195 orthologues and 53 paralogues.
ALK Products (3)
| mRNA | Protein | Name |
|---|---|---|
| XM_015112031.2 | XP_014967517.2 | ALK tyrosine kinase receptor isoform X1 |
| XM_028831808.1 | XP_028687641.1 | ALK tyrosine kinase receptor isoform X2 |
| XM_028831809.1 | XP_028687642.1 | ALK tyrosine kinase receptor isoform X3 |
ALK Protein Structure
MAM
MAM: cl27660 (265 - 423)
LDLa
LDLa: smart00192 (440 - 466)
MAM
MAM: pfam00629 (479 - 634)
PTKc_ALK_LTK
PTKc_ALK_LTK: cd05036 (1108 - 1384)
- 0
- 300
- 600
- 900
- 1200
- 1500
- 1620 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ALK tyrosine kinase receptor |
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(20)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-50878 | Crizotinib | Inhibitor | 99.97% | Yes |
| HY-12215 | Lorlatinib | 99.99% | Yes | |
| HY-12678 | Entrectinib | 99.26% | Yes | |
| HY-15656 | Ceritinib | Inhibitor | 99.95% | Yes |
| HY-13011 | Alectinib | Inhibitor | 99.78% | Yes |
| HY-12857 | Brigatinib | Inhibitor | 99.98% | Yes |
| HY-103022 | Repotrectinib | Inhibitor | 99.95% | Unkown |
| HY-15656A | Ceritinib dihydrochloride | Inhibitor | 99.90% | Yes |
| HY-13011A | Alectinib Hydrochloride | Inhibitor | 99.92% | Yes |
| HY-50878A | Crizotinib hydrochloride | 99.86% | Yes | |
| HY-103714 | Ensartinib | Inhibitor | 99.93% | Unkown |
| HY-103714A | Ensartinib dihydrochloride | Inhibitor | 99.73% | Unkown |
| HY-145574 | Iruplinalkib | Inhibitor | 99.62% | Unkown |
| HY-100375 | Diroximel fumarate | Activator | 99.60% | Yes |
| HY-123689 | Samidorphan | 99.04% | Unkown | |
| HY-12215R | Lorlatinib (Standard) | 99.92% | Unkown | |
| HY-13011AR | Alectinib Hydrochloride (Standard) | Inhibitor | 99.80% | Unkown |
| HY-50878B | Crizotinib acetate | Inhibitor | / | Unkown |
| HY-15656AR | Ceritinib dihydrochloride (Standard) | Inhibitor | / | Unkown |
| HY-15656R | Ceritinib (Standard) | Inhibitor | 99.72% | Unkown |
Clinical Phase
Bioactive Molecules
(26)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-15656B | Ceritinib mesylate | Inhibitor | / | Phase 4 |
| HY-156467 | Neladalkib | 99.87% | Phase 3 | |
| HY-172412 | Alixorexton | Agonist | 99.96% | Phase 3 |
| HY-172412A | Alixorexton enantiomer | Agonist | 99.42% | Phase 3 |
| HY-112801 | F-1 | Inhibitor | 98.03% | Phase 3 |
| HY-180970 | TD-004 | Degrader | / | Phase 3 |
| HY-N0679S | Retinyl acetate-d3 | / | Phase 3 | |
| HY-19928 | Vactosertib | Inhibitor | 99.53% | Phase 2 |
| HY-103021 | LY3200882 | Inhibitor | 99.87% | Phase 2 |
| HY-117887 | Fidrisertib | Inhibitor | 98.58% | Phase 2 |
| HY-145608 | Zilurgisertib | Inhibitor | 98.25% | Phase 2 |
| HY-172240 | Tosposertib | Inhibitor | 99.89% | Phase 2 |
| HY-17603 | Belizatinib | Inhibitor | 99.62% | Phase 2 |
| HY-16590 | X-376 | Inhibitor | 98.10% | Phase 2 |
| HY-136773 | KER047 | Inhibitor | 98.80% | Phase 2 |
| HY-109179A | Itacnosertib hydrochloride | Inhibitor | 99.43% | Phase 2 |
| HY-109084A | Conteltinib tetrahydrochloride | Inhibitor | 99.60% | Phase 2 |
| HY-136788A | ALK4290 dihydrochloride | Inhibitor | / | Phase 2 |
| HY-169482 | ALK protein ligand-1 | Inhibitor | / | Phase 2 |
| HY-15841 | CEP-37440 | Inhibitor | 99.91% | Phase 1 |
| HY-139279 | Zotizalkib | Inhibitor | 98.02% | Phase 1 |
| HY-155163 | APG-2449 | Inhibitor | 98.93% | Phase 1 |
| HY-13326 | ASP3026 | 99.88% | Phase 1 | |
| HY-135366 | HPN-01 | Inhibitor | 98.61% | Phase 1 |
| HY-142287 | Con B-1 | Inhibitor | / | Phase 1 |
| HY-16769 | Panulisib | / | Phase 1 |
Inhibitory Antibodies
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-P99353 | Ascrinvacumab | Inhibitor | 97.45% | Phase 2 |
| HY-P99752 | Nemvaleukin alfa | 99.50% | Phase 2 | |
| HY-P990022 | Prafnosbart | Inhibitor | / | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(298)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-10431 | SB-431542 | Inhibitor | 99.85% | Unkown |
| HY-10432 | A 83-01 | Inhibitor | 99.41% | Unkown |
| HY-13418A | Dorsomorphin | Inhibitor | 99.91% | Unkown |
| HY-12071 | LDN193189 | Inhibitor | 99.72% | Unkown |
| HY-13418 | Dorsomorphin dihydrochloride | Inhibitor | 99.91% | Unkown |
| HY-13012 | RepSox | Inhibitor | 99.92% | Unkown |
| HY-12043 | SB 525334 | Inhibitor | 99.97% | Unkown |
| HY-12071B | LDN193189 dihydrochloride | Inhibitor | 99.50% | Unkown |
| HY-12071A | LDN193189 Tetrahydrochloride | Inhibitor | 99.79% | Unkown |
| HY-10432A | A 83-01 sodium | Inhibitor | 98.03% | Unkown |
| HY-131442 | Alkyne-phenol | 99.72% | Unkown | |
| HY-13521 | SB-505124 | Inhibitor | 99.73% | Unkown |
| HY-W040304 | Alkynyl Palmitic Acid | 99.90% | Unkown | |
| HY-16712 | LDN-214117 | Inhibitor | 99.54% | Unkown |
| HY-12278 | K02288 | Inhibitor | 99.95% | Unkown |
| HY-13227 | SD-208 | Inhibitor | 99.87% | Unkown |
| HY-10326 | GW788388 | Inhibitor | 99.92% | Unkown |
| HY-13012G | RepSox (GMP) | Inhibitor | / | Unkown |
| HY-10192 | NVP-TAE 684 | 99.70% | Unkown | |
| HY-15609 | AZD-3463 | 99.31% | Unkown | |
| HY-15897 | LDN-212854 | Inhibitor | 99.62% | Unkown |
| HY-10431R | SB-431542 (Standard) | Inhibitor | 99.51% | Unkown |
| HY-12274 | ML347 | Inhibitor | 99.94% | Unkown |
| HY-112155 | MS4078 | Inhibitor | 99.72% | Unkown |
| HY-12953 | R-268712 | Inhibitor | 99.92% | Unkown |
| HY-19928A | Vactosertib Hydrochloride | Inhibitor | 99.22% | Yes |
| HY-13020 | GSK1838705A | Inhibitor | 99.58% | Unkown |
| HY-150169 | THRX-144644 | Inhibitor | 99.90% | Unkown |
| HY-12071G | LDN193189 (GMP) | Inhibitor | / | Unkown |
| HY-153386 | CPD-1224 | Inhibitor | 99.83% | Unkown |
| HY-10432G | A 83-01 (GMP) | Inhibitor | / | Unkown |
| HY-111482 | SM 16 | Inhibitor | 99.82% | Unkown |
| HY-123919 | TL13-112 | Inhibitor | 98.01% | Unkown |
| HY-148234 | M4K2234 | Inhibitor | 98.31% | Unkown |
| HY-168990 | Ontunisertib | Inhibitor | 99.95% | Unkown |
| HY-123856 | MY10 | 99.86% | Unkown | |
| HY-78349 | A 77-01 | Inhibitor | 99.92% | Unkown |
| HY-109084 | Conteltinib | Inhibitor | 98.82% | Unkown |
| HY-18758 | IN-1130 | Inhibitor | 99.93% | Unkown |
| HY-160506 | PRO-6E | 99.10% | Unkown | |
| HY-12071C | LDN193189 hydrochloride | Inhibitor | 98.62% | Unkown |
| HY-144043 | ALK5-IN-8 | Inhibitor | 98.21% | Unkown |
| HY-19628 | OD36 | Inhibitor | 99.33% | Unkown |
| HY-10432R | A 83-01 (Standard) | Inhibitor | / | Unkown |
| HY-18766 | EW-7195 | Inhibitor | 98.84% | Unkown |
| HY-122856 | AZ12601011 | Inhibitor | 99.78% | Unkown |
| HY-13464 | ALK-IN-1 | Inhibitor | 99.42% | Unkown |
| HY-18030A | CEP-28122 mesylate salt | Inhibitor | 99.92% | Unkown |
| HY-112815 | ALK2-IN-2 | Inhibitor | 99.93% | Unkown |
| HY-109179 | Itacnosertib | Inhibitor | 99.06% | Unkown |
| HY-147219A | SIAIS164018 hydrochloride | 98.06% | Unkown | |
| HY-N4107 | Phyllanthin | Inhibitor | 99.97% | Unkown |
| HY-122582 | TL13-12 | Degrader | 98.16% | Unkown |
| HY-N1510 | Kaempferol 3-O-gentiobioside | Inhibitor | 99.88% | Unkown |
| HY-13521A | SB-505124 hydrochloride | Inhibitor | 98.52% | Unkown |
| HY-112156 | MS4077 | Inhibitor | 99.66% | Unkown |
| HY-136788 | ALK4290 | Inhibitor | 99.79% | Unkown |
| HY-125851 | TP-008 | Inhibitor | 99.42% | Unkown |
| HY-149591 | M4K-2009 | Inhibitor | 99.35% | Unkown |
| HY-150910 | Brigatinib C | Inhibitor | 99.72% | Unkown |
| HY-160237 | HYL001 | Inhibitor | 99.94% | Unkown |
| HY-159147 | SIAIS039 | 99.68% | Unkown | |
| HY-10327 | GW-6604 | Inhibitor | 98.0% | Unkown |
| HY-118528A | TP0427736 hydrochloride | Inhibitor | 99.91% | Unkown |
| HY-12678S1 | Entrectinib-d8 | 99.82% | Unkown | |
| HY-13783 | BIBF0775 | Inhibitor | 99.42% | Unkown |
| HY-137918 | TGF-βRI inhibitor 3 | Inhibitor | 99.16% | Unkown |
| HY-155939 | M4K2163 dihydrochloride | Inhibitor | 98.58% | Unkown |
| HY-50878S | Crizotinib-d5 | 99.60% | Unkown | |
| HY-P11354A | THR-123 TFA | 99.91% | Unkown | |
| HY-112140 | JH-VIII-157-02 | Inhibitor | 98.98% | Unkown |
| HY-152845 | Ficonalkib | Inhibitor | 98.89% | Unkown |
| HY-12273R | DMH-1 (Standard) | Inhibitor | 99.78% | Unkown |
| HY-12331 | KRCA-0008 | 96.19% | Unkown | |
| HY-136773A | KER047 succinate | Inhibitor | 99.17% | Unkown |
| HY-15358 | ALK inhibitor 2 | Inhibitor | 99.72% | Unkown |
| HY-160520 | ALK-IN-28 | Inhibitor | 99.30% | Unkown |
| HY-164397 | XMU-MP-5 | 99.00% | Unkown | |
| HY-19990 | ALK kinase inhibitor-1 | Inhibitor | 99.87% | Unkown |
| HY-13011S | Alectinib-d8 | Inhibitor | 98.09% | Unkown |
| HY-151289 | ALK5-IN-34 | Inhibitor | 98.21% | Unkown |
| HY-15801 | HG-14-10-04 | Inhibitor | 98.53% | Unkown |
| HY-173149 | CDD-2789 | Inhibitor | / | Unkown |
| HY-N4126 | 6-Demethoxytangeretin | Inhibitor | 99.37% | Unkown |
| HY-P992188 | Anti-ALK7 Antibody | 97.93% | Unkown | |
| HY-111752 | EML4-ALK kinase inhibitor 1 | Inhibitor | 98.02% | Unkown |
| HY-12678S | Entrectinib-d4 | Inhibitor | / | Unkown |
| HY-135887 | ZX-29 | 98.59% | Unkown | |
| HY-136194 | TL13-22 | Inhibitor | 99.71% | Unkown |
| HY-147219 | SIAIS164018 | / | Unkown | |
| HY-15357 | ALK inhibitor 1 | Inhibitor | 99.16% | Unkown |
| HY-156432 | ALK-IN-26 | 99.87% | Unkown | |
| HY-156467A | Neladalkib TFA | 99.70% | Unkown | |
| HY-15656S | Ceritinib-d7 | Inhibitor | 98.00% | Unkown |
| HY-169481 | AP-1 | 97.8% | Unkown | |
| HY-170928 | DA-0157 | Inhibitor | 99.59% | Unkown |
| HY-19628A | OD36 hydrochloride | Inhibitor | / | Unkown |
| HY-123689S | Samidorphan-d4 | Antagonist | / | Unkown |
| HY-123689S1 | Samidorphan-d5 | Antagonist | / | Unkown |
| HY-N12973 | Peonidin 3-arabinoside | 95.0% | Unkown | |
| HY-RS00598 | ALK Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-18030 | CEP-28122 | Inhibitor | / | Unkown |
| HY-111416 | WY-135 | Inhibitor | / | Unkown |
| HY-12215S2 | Deulorlatinib | 99.84% | Unkown | |
| HY-128569 | ALK-IN-5 | Inhibitor | / | Unkown |
| HY-128596 | ALK-IN-6 | Inhibitor | / | Unkown |
| HY-13011S1 | Alectinib-d6 | Inhibitor | 98.05% | Unkown |
| HY-132229 | LPM4870108 | Inhibitor | / | Unkown |
| HY-135509 | Lorlatinib acetate | / | Unkown | |
| HY-111277 | CEP-14513 | / | Unkown | |
| HY-131909 | CJ-2360 | Inhibitor | / | Unkown |
| HY-184540 | ALK ligand-2 | Ligand | / | Unkown |
| HY-184541 | ALK protein ligand-1-PEG2-N3 | Ligand | / | Unkown |
| HY-105369 | KF-20444 | / | Unkown | |
| HY-108230 | ALK-IN-12 | Inhibitor | / | Unkown |
| HY-110347 | Mps1-IN-1 dihydrochloride | Inhibitor | / | Unkown |
| HY-112414 | ALK2-IN-7 | Inhibitor | / | Unkown |
| HY-112877 | ALK-5-IN-1 | Inhibitor | / | Unkown |
| HY-116636 | KRCA-0377 | Inhibitor | / | Unkown |
| HY-117806 | TSR-011-isomer | / | Unkown | |
| HY-120387 | SMU-B | Inhibitor | / | Unkown |
| HY-120663 | KRCA-0713 | Inhibitor | / | Unkown |
| HY-12278G | K02288 (GMP) | Inhibitor | / | Unkown |
| HY-12857S | Brigatinib-13C6 | Inhibitor | / | Unkown |
| HY-12973 | ALK-IN-13 | Inhibitor | / | Unkown |
| HY-13012S | RepSox-d5 | / | Unkown | |
| HY-130794 | ALK/ROS1-IN-1 | Inhibitor | / | Unkown |
| HY-131244 | ALK-IN-9 | Inhibitor | / | Unkown |
| HY-13227G | SD-208 (GMP) | Inhibitor | / | Unkown |
| HY-136195 | TL13-110 | Inhibitor | / | Unkown |
| HY-142949 | ALK5-IN-7 | Inhibitor | / | Unkown |
| HY-142950 | ALK5-IN-6 | Inhibitor | / | Unkown |
| HY-143557 | Trk-IN-7 | Inhibitor | / | Unkown |
| HY-144423 | Trk-IN-10 | Inhibitor | / | Unkown |
| HY-144437 | ALK5-IN-9 | Inhibitor | / | Unkown |
| HY-144732 | TRK/ALK-IN-1 | Inhibitor | / | Unkown |
| HY-145855 | J-1063 | Inhibitor | / | Unkown |
| HY-146022 | SIAIS117 | Degrader | / | Unkown |
| HY-146408 | ALK-IN-21 | Inhibitor | / | Unkown |
| HY-146694 | RIPK2-IN-1 | Inhibitor | / | Unkown |
| HY-146780 | TGFβRI-IN-4 | Inhibitor | / | Unkown |
| HY-147206 | Biotin-PEG600-Alk | / | Unkown | |
| HY-147206A | Biotin-PEG1000-Alk | / | Unkown | |
| HY-147206B | Biotin-PEG2000-Alk | / | Unkown | |
| HY-147206C | Biotin-PEG3400-Alk | / | Unkown | |
| HY-147206D | Biotin-PEG5000-Alk | / | Unkown | |
| HY-147206E | Biotin-PEG10000-Alk | / | Unkown | |
| HY-147206F | Biotin-PEG20000-Alk | / | Unkown | |
| HY-147833 | ALK-IN-22 | / | Unkown | |
| HY-148246 | MU1700 | Inhibitor | / | Unkown |
| HY-149403 | J-1048 | Inhibitor | / | Unkown |
| HY-151155 | ALK-IN-23 | Inhibitor | / | Unkown |
| HY-151233 | ALK5-IN-10 | Inhibitor | / | Unkown |
| HY-151270 | ALK5-IN-25 | Inhibitor | / | Unkown |
| HY-151272 | ALK5-IN-26 | Inhibitor | / | Unkown |
| HY-151273 | ALK5-IN-27 | Inhibitor | / | Unkown |
| HY-151275 | ALK5-IN-28 | Inhibitor | / | Unkown |
| HY-151277 | ALK5-IN-29 | Inhibitor | / | Unkown |
| HY-151279 | ALK5-IN-30 | Inhibitor | / | Unkown |
| HY-151281 | ALK5-IN-31 | Inhibitor | / | Unkown |
| HY-151282 | ALK5-IN-32 | Inhibitor | / | Unkown |
| HY-151283 | ALK5-IN-33 | Inhibitor | / | Unkown |
| HY-153246 | ALK2-IN-5 | Inhibitor | / | Unkown |
| HY-153503 | ALK-IN-24 | Inhibitor | / | Unkown |
| HY-155227 | ALK/EGFR-IN-1 | / | Unkown | |
| HY-155227A | ALK/EGFR-IN-2 | Inhibitor | / | Unkown |
| HY-155227B | ALK/EGFR-IN-3 | Inhibitor | / | Unkown |
| HY-155227S | ALK/EGFR-IN-1-d5 | / | Unkown | |
| HY-156470 | Multi-kinase-IN-6 | / | Unkown | |
| HY-157391 | ALK/ROS1-IN-3 | Inhibitor | / | Unkown |
| HY-159952 | ALK5-IN-84 | Inhibitor | / | Unkown |
| HY-161350 | ALK/HDAC-IN-1 | Inhibitor | / | Unkown |
| HY-161376 | M4K2281 | Inhibitor | / | Unkown |
| HY-161377 | M4K2306 | Inhibitor | / | Unkown |
| HY-161662 | ALK5-IN-80 | Inhibitor | / | Unkown |
| HY-161749 | PROTAC ALK degrader-1 | Degrader | / | Unkown |
| HY-161750 | PROTAC ALK degrader-2 | Degrader | / | Unkown |
| HY-161910 | SH-E4A-66 | Inhibitor | / | Unkown |
| HY-163429 | J-1149 | Inhibitor | / | Unkown |
| HY-163507 | ALK5-IN-79 | Inhibitor | / | Unkown |
| HY-165284 | CM-118 | Inhibitor | / | Unkown |
| HY-167388 | PLLA5000-PEG5000-ALK | / | Unkown | |
| HY-167389 | PLLA5000-PEG3000-ALK | / | Unkown | |
| HY-167390 | PLLA5000-PEG2000-ALK | / | Unkown | |
| HY-167391 | PLLA5000-PEG1000-ALK | / | Unkown | |
| HY-167392 | PLLA4000-PEG5000-ALK | / | Unkown | |
| HY-167393 | PLLA4000-PEG3000-ALK | / | Unkown | |
| HY-167394 | PLLA4000-PEG2000-ALK | / | Unkown | |
| HY-167395 | PLLA4000-PEG1000-ALK | / | Unkown | |
| HY-167396 | PLLA3000-PEG5000-ALK | / | Unkown | |
| HY-167397 | PLLA3000-PEG3000-ALK | / | Unkown | |
| HY-167398 | PLLA3000-PEG2000-ALK | / | Unkown | |
| HY-167399 | PLLA3000-PEG1000-ALK | / | Unkown | |
| HY-167400 | PLLA2000-PEG5000-ALK | / | Unkown | |
| HY-167401 | PLLA2000-PEG3000-ALK | / | Unkown | |
| HY-167402 | PLLA2000-PEG2000-ALK | / | Unkown | |
| HY-167403 | PLLA2000-PEG1000-ALK | / | Unkown | |
| HY-167404 | PLLA1000-PEG5000-ALK | / | Unkown | |
| HY-167405 | PLLA1000-PEG3000-ALK | / | Unkown | |
| HY-167406 | PLLA1000-PEG2000-ALK | / | Unkown | |
| HY-167407 | PLLA1000-PEG1000-ALK | / | Unkown | |
| HY-167408 | PLLA10000-PEG5000-ALK | / | Unkown | |
| HY-167409 | PLLA10000-PEG3000-ALK | / | Unkown | |
| HY-167410 | PLLA10000-PEG2000-ALK | / | Unkown | |
| HY-167864 | M4K2308 | Inhibitor | / | Unkown |
| HY-168163 | CDK12/13 ligand 1 | Degrader | / | Unkown |
| HY-168513 | ALK-IN-29 | Inhibitor | / | Unkown |
| HY-168551 | PROTAC ALK degrader-3 | / | Unkown | |
| HY-168552 | 3-Hydroxyazetidine-Cyclohexanol | / | Unkown | |
| HY-168553 | 3-Hydroxyazetidine-Cyclohexanol-5-Aminothalidomide | / | Unkown | |
| HY-168607 | ALK5-IN-83 | Inhibitor | / | Unkown |
| HY-170405 | YB-3-17 | Inhibitor | 98.19% | Unkown |
| HY-170418 | ALK/ROS1-IN-5 | / | Unkown | |
| HY-170592 | dALK-3 | Degrader | / | Unkown |
| HY-171248 | CDD-1115 | Inhibitor | / | Unkown |
| HY-171825 | SIAIS001 | Degrader | / | Unkown |
| HY-172426 | Dirozalkib | Inhibitor | / | Unkown |
| HY-172958 | F6524-1593 | Inhibitor | / | Unkown |
| HY-173007 | ALK/PI3K/AKT-IN-1 | / | Unkown | |
| HY-173493 | ALK-IN-31 | / | Unkown | |
| HY-174314 | WZH-15-125 | Inhibitor | / | Unkown |
| HY-174315 | WZH-17-002 | Degrader | / | Unkown |
| HY-174368 | PROTAC EML4-ALK Degrader-1 | / | Unkown | |
| HY-175271 | JWJ-01-378 | Degrader | / | Unkown |
| HY-175527 | ALK degrader 2 | / | Unkown | |
| HY-175528 | ALK ligand-Linker Conjugate 1 | / | Unkown | |
| HY-175849 | ALK degrader 1 | / | Unkown | |
| HY-17603A | (E)-Belizatinib | Inhibitor | / | Unkown |
| HY-17661 | Depiperazine-DM3189 | Inhibitor | / | Unkown |
| HY-176941 | ALK2-IN-6 | Inhibitor | / | Unkown |
| HY-177945 | MS99-β-Gal | Degrader | / | Unkown |
| HY-178057 | EGFR-IN-176 | / | Unkown | |
| HY-178231 | Finbosertib | Inhibitor | / | Unkown |
| HY-178391 | SMU-037 | / | Unkown | |
| HY-179732 | PROTAC ALK degrader-4 | / | Unkown | |
| HY-179733 | CRBN ligand-191 | / | Unkown | |
| HY-179735 | CRBN ligand-192 | / | Unkown | |
| HY-18030B | CEP-28122 mesylate hydrochloride | Inhibitor | / | Unkown |
| HY-180811 | ALK/HDAC-IN-2 | / | Unkown | |
| HY-180818 | ALK-IN-33 | / | Unkown | |
| HY-180956 | PROTAC ALK degrader-5 | / | Unkown | |
| HY-180964 | Lys-PEG3-BA | Degrader | / | Unkown |
| HY-180965 | Pro-PEG3-BA | / | Unkown | |
| HY-180966 | Gly-PEG3-BA | Degrader | / | Unkown |
| HY-180972 | PROTAC EML4-ALK Degrader-2 | Inhibitor | / | Unkown |
| HY-181113 | ALK-IN-34 | Inhibitor | / | Unkown |
| HY-181139 | ALK5-IN-86 | Inhibitor | / | Unkown |
| HY-182057 | ALK degrader 4 | Degrader | / | Unkown |
| HY-182087 | ALK degrader 3 | Degrader | / | Unkown |
| HY-182547 | LY580276 | Inhibitor | / | Unkown |
| HY-183358 | ALK-IN-37 | / | Unkown | |
| HY-183440 | Amine-C2-piperazine-C4-OH | / | Unkown | |
| HY-183441 | ALK5 ligand-1 | Ligand | / | Unkown |
| HY-183442 | ALK5 ligand-1-amine-C2-piperazine-C4-OH | Ligand | / | Unkown |
| HY-183717 | M4K3233 | / | Unkown | |
| HY-183718 | M4K3250 | Degrader | / | Unkown |
| HY-183719 | M4K2009-CH2-piperidine | Ligand | / | Unkown |
| HY-183720 | M4K2163 | Inhibitor | / | Unkown |
| HY-183721 | M4K2163-CH2-piperidine | Ligand | / | Unkown |
| HY-183767 | Aurora kinase/ALK-IN-1 | / | Unkown | |
| HY-183785 | PROTAC ALK5 Degrader-1 | Degrader | / | Unkown |
| HY-183950 | ALK5-IN-87 | Inhibitor | / | Unkown |
| HY-184652 | LRRK2/JNK3-IN-1 | Inhibitor | / | Unkown |
| HY-185430 | HM-279 | Inhibitor | / | Unkown |
| HY-187801 | SH-CER-6 | Inhibitor | / | Unkown |
| HY-50878AS | Crizotinib-d9 hydrochloride | / | Unkown | |
| HY-E70642 | ALK C1156Y Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70643 | ALK F1174L Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70644 | ALK F1174S Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70645 | ALK G1202R Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70646 | ALK L1196M Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70647 | ALK R1275Q Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70713 | EML4 ALK Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70714 | EML4 ALK F1174L Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70760 | NPM1 ALK Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-E70761 | NPM1 ALK F1174L Recombinant Human Active Protein Kinase | / | Unkown | |
| HY-P11354 | THR-123 | / | Unkown | |
| HY-RS00599 | Alk Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS00600 | ALK Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-W1139353 | Tetraasterane | / | Unkown | |
| HY-W707119 | RepSox hydrochloride | Inhibitor | / | Unkown |
| HY-W754809 | ALK ligand-1 | Ligand | / | Unkown |
| HY-107386 | PF-03671148 | Inhibitor | / | Unkown |
| HY-118528 | TP0427736 | Inhibitor | / | Unkown |
| HY-12071BR | LDN193189 dihydrochloride (Standard) | Inhibitor | / | Unkown |
| HY-12857S2 | Brigatinib-d11 | Inhibitor | / | Unkown |
| HY-14243 | CEP-14083 | Inhibitor | / | Unkown |
| HY-149591A | M4K2009 hydrochloride | Inhibitor | / | Unkown |
| HY-158905 | MTDB-Alkyne | Degrader | / | Unkown |
| HY-160172 | ALK/ROS1-IN-4 | Inhibitor | / | Unkown |
| HY-160172A | ALK/ROS1-IN-4 hydrate | Inhibitor | / | Unkown |
| HY-162902 | ALK5-IN-82 | Inhibitor | / | Unkown |
| HY-179400 | LDN-193688 | Inhibitor | / | Unkown |
| HY-184317 | M4K2149 | Inhibitor | / | Unkown |
| HY-184863 | PLK1-IN-17 | Inhibitor | / | Unkown |
| HY-50878S1 | Crizotinib-d8 | / | Unkown | |
| HY-50878S2 | Crizotinib-d9 | / | Unkown | |
| HY-W814315 | Alectinib analog | / | Unkown |
Inhibitory Antibodies
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P991533 | DLX-521 | Inhibitor | / | Unkown |
| HY-P991855 | RKER-216 | Inhibitor | / | Unkown |
| HY-P991862 | CDX-0125-TEI Antibody | / | Unkown |
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