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  2. Il10 - interleukin 10 Gene

Il10 - interleukin 10 Gene

Rattus norvegicus

Also known as If2a; IL10X

Gene ID: 25325 | Gene type: protein coding

About Il10

Primary_assembly 13: 42,472,839-42,477,313 forward strand.mRatBN7.2:CM026986.1

This gene has 1 transcript (splice variant), 193 orthologues, 3 paralogues and is associated with 243 phenotypes. Biased expression in Spleen (RPKM 3.6), Thymus (RPKM 1.9) and 7 other tissues.

Summary

Enables interleukin-10 receptor binding activity. Involved in several processes, including cellular response to estradiol stimulus; liver regeneration; and negative regulation of nitric oxide biosynthetic process. Located in extracellular space. Used to study several diseases, including lung disease (multiple); perinatal necrotizing enterocolitis; sciatic neuropathy; toxic encephalopathy; and transient cerebral ischemia. Biomarker of several diseases, including artery disease (multiple); decubitus ulcer; lung disease (multiple); obstructive sleep apnea; and postpartum depression. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); gastrointestinal system Cancer (multiple); and hematologic Cancer (multiple). Orthologous to human IL10 (interleukin 10). [provided by Alliance of Genome Resources, Apr 2022]

Il10 Products(1)

mRNA Protein Name
NM_012854.2 NP_036986.2 interleukin-10 precursor

Il10 Protein Structure

IL10

IL10: cl02501 (13 - 125)

  • 0
  • 100
  • 200
  • 217 a.a.
Protein Preferred Names Protein Names

interleukin-10

CSIF

IL-10

cytokine synthesis inhibitory factor

interferon 2a

Recombinant Il10 Proteins

Cat. No. Product Name Accession Purity
HY-P7098 IL-10 Protein, Rat P29456 (S19-N178) ≥95%
HY-P7098A IL-10 Protein, Rat (CHO) P29456 (S19-N178) ≥95%

Orthologs Information

Species Symbol Source ID
Homo sapiens Il10 NCBI NCBI:3586
Macaca fascicularis Il10 NCBI NCBI:102133450
Mus musculus Il10 NCBI NCBI:16153
Susscrofa domestica Il10 NCBI