2. Gene
  3. Maoa - monoamine oxidase A Gene

Maoa - monoamine oxidase A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as 1110061B18Rik

Gene ID: 17161 | Gene type: protein coding

About Maoa

Chromosome X: 16,485,937-16,554,057 forward strand.GRCm39:CM001013.3

This gene has 1 transcript (splice variant), 147 orthologues, 9 paralogues and is associated with 28 phenotypes. Broad expression in large intestine adult (RPKM 27.2), colon adult (RPKM 1.2) and 19 other tissues.

Summary

Enables primary amine oxidase activity. Acts upstream of or within dopamine catabolic process and positive regulation of signal transduction. Located in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system ganglion; and sensory organ. Used to study Brunner Syndrome. Human ortholog(s) of this gene implicated in Alzheimer's disease; Brunner Syndrome; alcohol use disorder; autism spectrum disorder; and panic disorder. Orthologous to human MAOA (Monoamine Oxidase A). [provided by Alliance of Genome Resources, Apr 2022]

Maoa Products(1)

mRNA Protein Name
NM_173740.3 NP_776101.3 amine oxidase [flavin-containing] A

Maoa Protein Structure

YobN

YobN: COG1231 (14 - 462)

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  • 526 a.a.
Protein Preferred Names Protein Names

amine oxidase [flavin-containing] A

MAO-A

monoamine oxidase type A

Related Agents

Approval
Bioactive Molecules (18)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14536 Methylene Blue Inhibitor 98.08% Unkown
HY-14280 Entacapone Inhibitor 99.92% Yes
HY-N0159 Paeonol 99.98% Unkown
HY-A0091A Pargyline Inhibitor 99.77% Unkown
HY-A0091 Pargyline hydrochloride Inhibitor 99.91% Unkown
HY-B0534 Moclobemide Inhibitor 99.90% Yes
HY-70057 Safinamide Inhibitor 99.89% Yes
HY-B1359 Methylene blue trihydrate ≥98.0% Yes
HY-70057A Safinamide mesylate Inhibitor 99.87% Yes
HY-14196 Toloxatone Inhibitor 99.84% Unkown
HY-B0884A Minaprine dihydrochloride Inhibitor 99.76% Unkown
HY-D0958 Methylene blue hydrate Inhibitor / Unkown
HY-B1558A Bifemelane hydrochloride 98.83% Unkown
HY-100679 Pirlindole Inhibitor ≥98.0% Unkown
HY-B0884 Minaprine Inhibitor / Unkown
HY-100679A Pirlindole mesylate Inhibitor / Unkown
HY-14280R Entacapone (Standard) Inhibitor / Unkown
HY-14280A Entacapone sodium salt Inhibitor / Unkown
Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-N0529 Rosmarinic acid 99.70% Phase 4
HY-100178 CX-157 Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (59)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-14197A Clorgyline hydrochloride Inhibitor 99.70% Unkown
HY-W008566 Norharmane Inhibitor 99.46% Unkown
HY-19333 OG-L002 Inhibitor 99.81% Unkown
HY-110130 RN-1 dihydrochloride Inhibitor 99.75% Unkown
HY-16677A Mofegiline hydrochloride Inhibitor 99.57% Unkown
HY-131036 MAO-IN-M30 dihydrochloride Inhibitor 99.25% Unkown
HY-100588 VU0364770 Agonist 99.93% Unkown
HY-E70074 Monoamine oxidase, plasma / Unkown
HY-14201 Lazabemide Inhibitor 99.95% Unkown
HY-124591 TC-2153 Inhibitor 98.73% Unkown
HY-145259 HDAC6-IN-3 Inhibitor / Unkown
HY-156255 MAO-B-IN-25 Inhibitor 99.11% Unkown
HY-13339 Brofaromine Inhibitor 99.60% Unkown
HY-100027A Ro 41-1049 hydrochloride Inhibitor 99.96% Unkown
HY-14280S Entacapone-d10 Inhibitor ≥98.0% Unkown
HY-151466 HIF-1α-IN-5 Inhibitor / Unkown
HY-151596 MAO-A/5-HT2AR-IN-1 Inhibitor 99.71% Unkown
HY-W010130 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone Inhibitor 99.96% Unkown
HY-14260 RS 8359 Inhibitor 97.03% Unkown
HY-108048 Desoxypeganine Inhibitor / Unkown
HY-116097 PSB-1491 Inhibitor / Unkown
HY-119885A (±)-Amiflamine Inhibitor 99.23% Unkown
HY-120017 Befloxatone Inhibitor / Unkown
HY-121072 ASS234 Inhibitor / Unkown
HY-125515 Tetrahydroharmine Inhibitor / Unkown
HY-129449 AnnH31 Inhibitor 99.91% Unkown
HY-135265 Moclobemide N-Oxide Inhibitor / Unkown
HY-14202 Lazabemide hydrochloride Inhibitor / Unkown
HY-143438 2-PAT Inhibitor / Unkown
HY-143721 SSAO inhibitor-2 Inhibitor / Unkown
HY-144673 LSD1-IN-12 Inhibitor / Unkown
HY-144756 LSD1-IN-15 Inhibitor / Unkown
HY-144757 LSD1-IN-16 Inhibitor / Unkown
HY-144758 LSD1-IN-17 Inhibitor / Unkown
HY-149408 MAOA-IN-1 Inhibitor / Unkown
HY-149528 MAO-B-IN-24 Inhibitor / Unkown
HY-149978 LSD1-IN-26 / Unkown
HY-151094 FTEAA Inhibitor / Unkown
HY-151800 MAO-A/B-IN-2 Inhibitor / Unkown
HY-152109 AChE/MAO-IN-1 Inhibitor / Unkown
HY-152110 AChE/MAO-IN-2 Inhibitor / Unkown
HY-15386 Cimoxatone Inhibitor / Unkown
HY-154977 ETAP Inhibitor / Unkown
HY-157934 MAO-IN-4 Inhibitor / Unkown
HY-157981 AChE-IN-60 Inhibitor / Unkown
HY-157982 BChE-IN-28 Inhibitor / Unkown
HY-161240 MAO-B-IN-30 Inhibitor / Unkown
HY-163322 MAO-A inhibitor 2 Inhibitor / Unkown
HY-70057S1 Safinamide-d4-1 Inhibitor / Unkown
HY-B0534S1 Moclobemide-d4 Inhibitor ≥99.0% Unkown
HY-D0004 Azure B Inhibitor 96.08% Unkown
HY-N12134 Methyl piperate Inhibitor / Unkown
HY-N12485 MAO-A inhibitor 1 Inhibitor / Unkown
HY-N1638 1-Methyl-2-undecyl-4(1H)-quinolone Inhibitor / Unkown
HY-RS08019 MAOA Human Pre-designed siRNA Set A / Unkown
HY-RS08020 Maoa Mouse Pre-designed siRNA Set A / Unkown
HY-RS08021 Maoa Rat Pre-designed siRNA Set A / Unkown
HY-134664 8α-(2-Methylacryloyloxy)-hirsutinolide-13-O-acetate Inhibitor / Unkown
HY-W792513 WAY-620147 Inhibitor ≥98.0% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Maoa NCBI NCBI:4128