2. Gene
  3. Nav1 - neuron navigator 1 Gene

Nav1 - neuron navigator 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Gm38399; Pomfil3; Unc53h1; mKIAA1151; steerin-1; 9530089B19; 9930003A20Rik; C230080M11Rik

Gene ID: 215690 | Gene type: protein coding

About Nav1

Summary

Acts upstream of or within microtubule bundle formation and neuron migration. Located in axon initial segment and microtubule Cytoskeleton. Is expressed in several structures, including central nervous system; embryo mesenchyme; molar; peripheral nervous system ganglion; and sensory organ. Orthologous to human NAV1 (neuron navigator 1). [provided by Alliance of Genome Resources, Apr 2022]

Nav1 Products(1)

mRNA Protein Name
NM_173437.2 NP_775613.2 neuron navigator 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within microtubule bundle formation IDA
IDA: Inferred from direct assay
15797708 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
15797708 MGI
Cellular Component GO Annotation Evidence Reference Source
located in axon initial segment IDA
IDA: Inferred from direct assay
26671463 MGI
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
15797708 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neuron navigator 1

Steerin1

pore membrane and/or filament-interacting-like protein 3

Related Agents

Approval
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-148800 Suzetrigine Inhibitor 99.98% Unkown
HY-17429 Flecainide acetate Inhibitor 99.35% Unkown
HY-17355A Dexpramipexole dihydrochloride 99.94% Yes
HY-B0262 Methocarbamol Inhibitor 99.68% Unkown
HY-17355B Dexpramipexole 99.56% Yes
HY-17355AR Dexpramipexole dihydrochloride (Standard) / Unkown
Clinical Phase
Bioactive Molecules (20)
Cat. No. Product Name Effect
Purity Phase
HY-148410A Zorevunersen sodium Activator 99.27% Phase 3
HY-105285 Piromelatine 99.70% Phase 3
HY-148410 Zorevunersen Activator / Phase 3
HY-12883 PF 05089771 Inhibitor 99.87% Phase 2
HY-147423 Zandatrigine Inhibitor 99.28% Phase 2
HY-12796A Raxatrigine hydrochloride Inhibitor 99.10% Phase 2
HY-12796 Raxatrigine Inhibitor 99.85% Phase 2
HY-16723 Funapide Inhibitor 99.83% Phase 2
HY-131182 DS-1971a Inhibitor 99.30% Phase 2
HY-105283 PF 04531083 Antagonist 99.62% Phase 2
HY-125079 DSP-2230 Inhibitor 98.33% Phase 1
HY-114237 GDC-0276 Inhibitor 99.69% Phase 1
HY-139081 GDC-0310 Inhibitor 98.84% Phase 1
HY-103623 PF-05241328 Inhibitor 98.08% Phase 1
HY-114301 PF-06305591 Inhibitor 99.74% Phase 1
HY-101383 PF-01247324 Inhibitor 99.77% Phase 1
HY-122001 PF-05186462 Inhibitor 99.69% Phase 1
HY-114301A PF-06305591 dihydrate Inhibitor 99.84% Phase 1
HY-128794 PF-05150122 / Phase 1
HY-W040555 Norquetiapine dihydrochloride 99.91% Phase 1
Pre-clinical Phase
Bioactive Molecules (169)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-N6691 Veratridine Inhibitor 99.42% Unkown
HY-100001 SKF-96365 hydrochloride 99.93% Unkown
HY-11079 A-803467 Inhibitor 99.69% Unkown
HY-100345 AMTB hydrochloride Inhibitor 99.08% Unkown
HY-16787 ICA-121431 Inhibitor 99.35% Unkown
HY-12811 PF-04856264 Inhibitor 99.29% Unkown
HY-118952A PF-06456384 trihydrochloride Inhibitor 99.38% Unkown
HY-P1221A ProTx II TFA Inhibitor 99.55% Unkown
HY-107405 TC-N 1752 Inhibitor 99.67% Unkown
HY-157802 LTGO-33 Inhibitor 98.83% Unkown
HY-126429 Nav1.1 activator 1 Activator 98.98% Unkown
HY-B0824 Bifenthrin Activator 99.76% Yes
HY-148792 Relutrigine Inhibitor 99.33% Unkown
HY-157786 XPC-5462 Inhibitor 99.65% Unkown
HY-100727 AM-2099 Inhibitor 98.37% Unkown
HY-W052508 Norquetiapine 99.95% Unkown
HY-157784 XPC-7724 Inhibitor 99.46% Unkown
HY-164795A SBI-810 hydrochloride 99.55% Unkown
HY-133012 GFB-8438 Inhibitor 99.74% Unkown
HY-133910 Lu AE98134 Activator 98.07% Unkown
HY-171244 Sodium Channel inhibitor 6 Inhibitor 99.93% Unkown
HY-139346 VX-150 Inhibitor 98.36% Unkown
HY-19958 XEN907 Inhibitor 98.74% Unkown
HY-110325 PF-04885614 Inhibitor 97.00% Unkown
HY-B1837 Cyfluthrin Inhibitor 99.52% Unkown
HY-P10234A Poneratoxin acetate Modulator 98.35% Unkown
HY-13985 Nav1.7 inhibitor Inhibitor 99.63% Unkown
HY-112279 GNE-131 Inhibitor 98.15% Unkown
HY-131870 GX-201 Inhibitor 98.89% Unkown
HY-145169 AZ194 Inhibitor 99.45% Unkown
HY-152166 NaV1.2/1.6 channel blocker-1 Inhibitor / Unkown
HY-N1847 3'-Methoxydaidzein Inhibitor 99.67% Unkown
HY-101789 Nav1.7-IN-3 Inhibitor 98.21% Unkown
HY-123824 GNE-0439 Inhibitor 99.80% Unkown
HY-20362 4-Azaindole 99.57% Unkown
HY-N0478 Neoline 98.0% Unkown
HY-125928 AA43279 Inhibitor 99.80% Unkown
HY-128772 XPC-6444 Inhibitor 98.93 Unkown
HY-155635 Nav1.8-IN-4 Inhibitor 99.78% Unkown
HY-P1218B Phrixotoxin 3-NH2 TFA Inhibitor 98.96% Unkown
HY-119934 NaV1.7 inhibitor-1 Inhibitor 99.17% Unkown
HY-123825 GX-674 Antagonist 98.45% Unkown
HY-143481 Nav1.8-IN-2 Inhibitor 99.83% Unkown
HY-157802A (S)-LTGO-33 Inhibitor 99.41% Unkown
HY-P1220A Huwentoxin-IV TFA Inhibitor 99.18% Unkown
HY-P5807A Cn2 toxin TFA Agonist 96.59% Unkown
HY-148410C Zorevunensen negative control Activator 99.28% Unkown
HY-12883A PF-05198007 Inhibitor 99.27% Unkown
HY-146069 ABBV-318 Inhibitor 98.72% Unkown
HY-156596 Aneratrigine Inhibitor 99.60% Unkown
HY-178281 E0199 99.89% Unkown
HY-125942 SKF-96365 99.97% Unkown
HY-178494 Nav1.7-IN-19 Inhibitor 98.87% Unkown
HY-P1073 ProTx-I Inhibitor 95.15% Unkown
HY-P1441A Mambalgin 1 TFA Inhibitor 95.72% Unkown
HY-P1681A GpTx-1 TFA Antagonist 99.56% Unkown
HY-18689 SYM2206 Antagonist 99.83% Unkown
HY-108425B (Rac)-AMG8379 Antagonist 99.25% Unkown
HY-16723A (R)-Funapide Inhibitor 99.22% Unkown
HY-123414 GX-936 Inhibitor 97.06% Unkown
HY-155058 Nav1.3 channel inhibitor 1 Inhibitor / Unkown
HY-163855 KGP-25 Inhibitor 95.0% Unkown
HY-164795 SBI-810 98.25% Unkown
HY-172903 Nav1.8-IN-16 Inhibitor / Unkown
HY-19366 Nav1.7-IN-2 Inhibitor 98.28% Unkown
HY-P1443 OD1 Modulator 99.40% Unkown
HY-P5160A Phlotoxin-1 TFA Inhibitor 92.73% Unkown
HY-P5786 Heteropodatoxin-1 / Unkown
HY-RS09046 NAV1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-123833 PF-05661014 Modulator 99.56% Unkown
HY-102998 Nav1.7-IN-6 Inhibitor / Unkown
HY-108425 AMG8379 Antagonist / Unkown
HY-126291 GNE-616 Inhibitor / Unkown
HY-183566 MK-5661 Inhibitor / Unkown
HY-W052508S Norquetiapine-d8 / Unkown
HY-108425A AMG8380 Inhibitor / Unkown
HY-116137 Nav1.7-IN-17 / Unkown
HY-117714 AZD-3161 Inhibitor / Unkown
HY-118952 PF-06456384 Inhibitor / Unkown
HY-120774 GS-462808 Inhibitor / Unkown
HY-126005 VGSC blocker-1 Inhibitor / Unkown
HY-12883B PF 05089771 tosylate Inhibitor / Unkown
HY-132133 Nav1.8-IN-1 Inhibitor / Unkown
HY-135495 AM-0466 Inhibitor / Unkown
HY-138816 Nav1.7-IN-15 Antagonist / Unkown
HY-141547 Nav1.7-IN-8 Inhibitor / Unkown
HY-149944 Analgesic agent-2 Inhibitor / Unkown
HY-149994 DS43260857 Inhibitor / Unkown
HY-155236 Ancistrotecine B Inhibitor / Unkown
HY-158979 Nav1.8-IN-14 Inhibitor / Unkown
HY-159094 Nav1.8-IN-15 Inhibitor / Unkown
HY-160588 Nav1.8-IN-7 Inhibitor / Unkown
HY-160589 Nav1.8-IN-8 Inhibitor / Unkown
HY-160591 Nav1.8-IN-10 Inhibitor / Unkown
HY-160592 Nav1.8-IN-11 Inhibitor / Unkown
HY-160593 Nav1.8-IN-12 Inhibitor / Unkown
HY-160663 Nav1.7 blocker 1 / Unkown
HY-161272 Nav1.8-IN-6 Inhibitor / Unkown
HY-161572 Nav1.8-IN-13 Inhibitor / Unkown
HY-162246 Nav1.8-IN-5 Inhibitor / Unkown
HY-162347 Nav1.7-IN-13 Inhibitor / Unkown
HY-162757 Anticonvulsant agent 5 Modulator / Unkown
HY-167852 GX-585 Inhibitor / Unkown
HY-169421 Nav1.7-IN-18 Inhibitor / Unkown
HY-170930 Anticonvulsant agent 9 / Unkown
HY-171778 QLS-81 Inhibitor / Unkown
HY-172933 Nav1.8 modulator 1 Modulator / Unkown
HY-172998 Nav1.8-IN-18 Inhibitor / Unkown
HY-172999 Nav1.8-IN-19 Inhibitor / Unkown
HY-17429S Flecainide-d4 acetate Inhibitor 99.0% Unkown
HY-174845 Nav1.8-IN-20 Inhibitor / Unkown
HY-175289 hERG-IN-3 Inhibitor / Unkown
HY-176065 Nav1.2-IN-1 Inhibitor / Unkown
HY-176911 Nav1.8-IN-21 Inhibitor / Unkown
HY-178344 Multi-target kinase-IN-6 Activator / Unkown
HY-178963 Nav1.2-IN-2 Inhibitor 99.82% Unkown
HY-179445 Nav1.7-IN-20 Inhibitor / Unkown
HY-181063 Nav1.5-IN-1 Inhibitor / Unkown
HY-181615 Nav1.8-IN-22 Inhibitor / Unkown
HY-182334 azo-Q2a Inhibitor / Unkown
HY-182710 DA-0218 Inhibitor / Unkown
HY-182831 Nav1.7-IN-22 Inhibitor / Unkown
HY-183646 Nav1.8-IN-23 Inhibitor / Unkown
HY-183709 Nav1.8-IN-24 Inhibitor / Unkown
HY-185333 Sodium Channel-IN-7 Inhibitor / Unkown
HY-B0262S Methocarbamol-d5 Inhibitor / Unkown
HY-B0262S2 Methocarbamol-13C,d3 Inhibitor / Unkown
HY-B1837S Cyfluthrin-d6 Inhibitor / Unkown
HY-P10234 Poneratoxin Modulator / Unkown
HY-P11045 JNJ63955918 Inhibitor / Unkown
HY-P1218 Phrixotoxin 3 Inhibitor / Unkown
HY-P1218A Phrixotoxin 3 TFA Inhibitor / Unkown
HY-P1219 Jingzhaotoxin-III Inhibitor / Unkown
HY-P1220 Huwentoxin-IV Inhibitor / Unkown
HY-P1221 ProTx II Inhibitor 98.34% Unkown
HY-P1681 GpTx-1 Antagonist / Unkown
HY-P5152 Scorpion toxin Tf2 Activator / Unkown
HY-P5153 ProTx-III Inhibitor / Unkown
HY-P5160 Phlotoxin-1 Inhibitor / Unkown
HY-P5164 GrTx1 Inhibitor / Unkown
HY-P5177 GsAF-II Inhibitor / Unkown
HY-P5781 δ-Theraphotoxin-Hm1b Inhibitor / Unkown
HY-P5782 δ-Theraphotoxin-Hm1a toxin Activator / Unkown
HY-P5783 δ-Buthitoxin-Hj2a Agonist / Unkown
HY-P5784 δ-Buthitoxin-Hj1a Agonist / Unkown
HY-P5790 μ-TRTX-Hd1a Inhibitor / Unkown
HY-P5793 GTx1-15 Inhibitor / Unkown
HY-P5795 GsAF-I Inhibitor / Unkown
HY-P5800 Phlo1b Inhibitor / Unkown
HY-P5801 Phlo1a Inhibitor / Unkown
HY-P5807 Cn2 toxin Activator / Unkown
HY-P5809 Pe1b Inhibitor / Unkown
HY-P5810 Ceratotoxin-2 Inhibitor / Unkown
HY-P5811 Ceratotoxin-1 Inhibitor / Unkown
HY-P5813 Cd1a Inhibitor / Unkown
HY-P5865 Tap1a Inhibitor / Unkown
HY-P5872 Jingzhaotoxin XI Inhibitor / Unkown
HY-P5900 m3-Huwentoxin IV Inhibitor / Unkown
HY-P5916 VSTx-3 Antagonist / Unkown
HY-W031620 VGSCs-IN-1 Inhibitor 99.92% Unkown
HY-W040171 Tefluthrin Activator / Unkown
HY-116194 NaV1.7 blocker-801 Inhibitor / Unkown
HY-118048 NAV 26 Inhibitor 99.79% Unkown
HY-17355BS Dexpramipexole-d3 dihydrochloride / Unkown
HY-175226 DPP8/9-IN-2 Inhibitor / Unkown
HY-182195 Suzetrigine N-oxide Inhibitor / Unkown
HY-185334 GNE-3565 Inhibitor / Unkown
HY-185335 Sodium Channel-IN-8 Inhibitor / Unkown
HY-B0262S1 Methocarbamol-d3 Inhibitor 98.15% Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990503 Anti-SCN9a/Nav1.7 Antibody Inhibitor 98.57% Unkown
HY-P990502 Anti-SCN11a/Nav1.9 Antibody Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nav1 NCBI NCBI:89796