2. Gene
  3. IL2 - interleukin 2 Gene

IL2 - interleukin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Oryctolagus cuniculus

Also known as TCGF

Gene ID: 100302458 | Gene type: protein coding

About IL2

Chromosome 15: 98,312,429-98,317,579 reverse strand.OryCun2.0:CM000804.1

This gene has 2 transcripts (splice variants) and 89 orthologues.

IL2 Products(2)

mRNA Protein Name
NM_001171099.1 NP_001164570.1 interleukin-2 isoform 2 precursor
NM_001163180.1 NP_001156652.1 interleukin-2 isoform 1 precursor

IL2 Protein Structure

IL2

IL2: pfam00715 (6 - 148)

  • 0
  • 100
  • 153 a.a.
Protein Preferred Names Protein Names

interleukin-2

T-cell growth factor

patial sequence of Interleukin-2

Related Agents

Approval
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13756 Tacrolimus 99.93% Unkown
HY-A0003 Lenalidomide Inducer 99.95% Yes
HY-13756A Tacrolimus monohydrate 99.67% Yes
HY-B1046 Clofazimine 99.79% Unkown
HY-A0003B Lenalidomide hemihydrate Inducer 99.98% Yes
HY-B0722 Histamine dihydrochloride Inhibitor 99.51% Yes
HY-A0003A Lenalidomide hydrochloride / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108738 Daclizumab Inhibitor ≥99.0% Unkown
Clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Phase
HY-N0594 Deacetylasperulosidic Acid Inhibitor 99.86% Phase 4
HY-113271 5-Androstenetriol Activator / Phase 4
HY-153220 NX-2127 Inhibitor 99.72% Phase 1
HY-132304 CC-90005 Inhibitor 99.67% Phase 1
HY-137131 DC-Chol hydrochloride 99.91% Phase 1
HY-173006 AZ3246 / Phase 1
Inhibitory Antibodies (9)
Cat. No. Product Name Effect
Purity Phase
HY-P99664 Inolimomab Inhibitor 98.78% Phase 3
HY-P99499 Cetrelimab ≥99.0% Phase 3
HY-P99159 Ivuxolimab Activator 95.32% Phase 2
HY-P99410 Ordesekimab Inhibitor 98.20% Phase 2
HY-P99752 Nemvaleukin alfa 99.50% Phase 2
HY-P99328 Tucotuzumab ≥95.0% Phase 2
HY-P99728 Melredableukin alfa 96.22% Phase 2
HY-P99479 Bifikafusp alfa Inhibitor / Phase 2
HY-P99498 Cergutuzumab amunaleukin Inhibitor 99.5% Phase 1
Pre-clinical Phase
Bioactive Molecules (104)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-136339 Cbl-b-IN-1 Inhibitor 99.68% Unkown
HY-110117 BIRT 377 Inhibitor 99.82% Unkown
HY-N6607 Tryptanthrin 99.89% Unkown
HY-138568 HPK1-IN-3 Inhibitor 98.61% Unkown
HY-18303 AMG-47a Inhibitor 99.19% Unkown
HY-110177 SP-100030 Inhibitor 99.57% Unkown
HY-N6939 Pseudolaric Acid B 99.47% Unkown
HY-131140 BD750 Inhibitor 99.10% Unkown
HY-133987 AP-1/NF-κB activation inhibitor 1 Inhibitor 99.03% Unkown
HY-162734 BRD5075 Inhibitor 98.08% Unkown
HY-113618B RO2959 monohydrochloride Inhibitor 98.21% Unkown
HY-N0534 Vitexin-2"-O-rhamnoside 99.36% Unkown
HY-N0600 Ginsenoside F3 Modulator 99.84% Unkown
HY-134820 MLT-943 Inhibitor 99.77% Unkown
HY-126328 PKC-theta inhibitor 1 Inhibitor 99.73% Unkown
HY-119424 SP4206 Inhibitor 98.55% Unkown
HY-13756S Tacrolimus-13C,d2 98.36% Unkown
HY-P1997 Ferrichrome Iron-free ≥99.0% Unkown
HY-106755 Tucaresol Inhibitor 98.95% Unkown
HY-21293 SU5201 Inhibitor 99.45% Unkown
HY-P3143 BMSpep-57 Inhibitor 99.84% Unkown
HY-P1453A CMD178 TFA Inhibitor 98.61% Unkown
HY-171034 PQA-18 Inhibitor 99.62% Unkown
HY-113618A RO2959 hydrochloride Inhibitor / Unkown
HY-150051 IL-2-IN-1 Inhibitor 99.95% Unkown
HY-P3143A BMSpep-57 hydrochloride Inhibitor 99.69% Unkown
HY-112778 NFAT Transcription Factor Regulator-1 Inhibitor 99.37% Unkown
HY-A0003S Lenalidomide-d5 Inducer 99.32% Unkown
HY-164756 PKCTheta-IN-2 Inhibitor 99.49% Unkown
HY-P1453 CMD178 Inhibitor / Unkown
HY-100849 JAK 3i Inhibitor / Unkown
HY-103390 Ro26-4550 TFA Antagonist / Unkown
HY-108161 LF 1695 Activator / Unkown
HY-110113 CTA056 Inhibitor / Unkown
HY-112335 Lck Inhibitor III Inhibitor / Unkown
HY-115464 NC1153 / Unkown
HY-115756 4-Maleimidosalicylic acid / Unkown
HY-117843 Ppc-1 / Unkown
HY-121743 Ro26-4550 Antagonist / Unkown
HY-121874 EP009 Inhibitor / Unkown
HY-135078 2,5-Deoxyfructosazine Inhibitor / Unkown
HY-141864 ITK/TRKA-IN-1 Inhibitor / Unkown
HY-142648A (R)-MLT-985 Inhibitor / Unkown
HY-145675A (R)-TCB2 / Unkown
HY-147504 Anticancer agent 63 / Unkown
HY-149206 HPK1-IN-33 Inhibitor / Unkown
HY-149232 HPK1-IN-35 Inhibitor / Unkown
HY-149916 A2AR-antagonist-1 Antagonist / Unkown
HY-149917 ITK degrader 1 Degrader / Unkown
HY-153952 Immuno modulator-1 Inhibitor / Unkown
HY-156149 CYP51/PD-L1-IN-1 Inhibitor / Unkown
HY-156150 CYP51/PD-L1-IN-2 Inhibitor / Unkown
HY-156151 CYP51/PD-L1-IN-3 Inhibitor / Unkown
HY-157569 PD1-PDL1-IN 2 / Unkown
HY-157838 HMC-B17 Inhibitor / Unkown
HY-159892 PD-1/PD-L1-IN-54 / Unkown
HY-159902 KRN7000 analog 3 Activator / Unkown
HY-161389 SP-alkyne Inhibitor / Unkown
HY-161390 SPC-alkyne Inhibitor / Unkown
HY-163194 Cbl-b-IN-16 Inhibitor / Unkown
HY-163496 HPK1-IN-45 Inhibitor / Unkown
HY-163747 VEGFR-2-IN-47 Inhibitor / Unkown
HY-163849 Mizoribine prodrug-1 / Unkown
HY-163850 Mizoribine prodrug-2 trifluoroacetate Inhibitor / Unkown
HY-168282 DD205-291 Degrader / Unkown
HY-168963 PROTAC BTK Degrader-13 / Unkown
HY-169317 DGKζ-IN-6 Inhibitor / Unkown
HY-169318 DGKζ-IN-7 Inhibitor / Unkown
HY-172107 HPK1-IN-56 / Unkown
HY-172594 HPK1-IN-57 / Unkown
HY-173311 Cbl-b-IN-28 / Unkown
HY-A0003S2 Lenalidomide-13C5,15N Inducer / Unkown
HY-N12988 Dihydrobonducellin Inhibitor / Unkown
HY-N1726 cis-Burchellin Inhibitor / Unkown
HY-P10544 Humanized anti-tac (HAT) binding peptide Inhibitor / Unkown
HY-P3083 N-Myristoyl-Lys-Arg-Thr-Leu-Arg Inhibitor / Unkown
HY-P3736 Myelopeptide-2 Inducer / Unkown
HY-P5870 KTX-Sp2 Inhibitor / Unkown
HY-RS06728 IL2 Human Pre-designed siRNA Set A / Unkown
HY-RS06729 Il2 Mouse Pre-designed siRNA Set A / Unkown
HY-RS06730 Il2 Rat Pre-designed siRNA Set A / Unkown
HY-RS06748 IL2RA Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06749 IL2RB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS06750 IL2RG Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-101687 Nosantine racemate / Unkown
HY-123187 AS2553627 Inhibitor / Unkown
HY-123590 BC12-4 Inhibitor / Unkown
HY-132243 NFAT Inhibitor-3 Inhibitor / Unkown
HY-13644 Gusperimus / Unkown
HY-13756S2 Tacrolimus-d3 / Unkown
HY-161335 HPK1-IN-43 / Unkown
HY-163902 SP100030 analogue 1 Inhibitor / Unkown
HY-170616 JH-FK-08 Inhibitor / Unkown
HY-171004 KRN7000 analog 8 / Unkown
HY-173077 PD-L1/LpxC-IN-1 Inhibitor / Unkown
HY-A0003S3 Lenalidomide-d4 Inducer / Unkown
HY-B0757 Vitamin E nicotinate Inhibitor / Unkown
HY-N12783 Digitoxigenin-3-O-β-D-quinovoside Inhibitor / Unkown
HY-N15307 Trigraecum Inhibitor / Unkown
HY-N15408 Terminaline Inhibitor / Unkown
HY-RS16278 Il2rb Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17342 Il2rb Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18825 Il2ra Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20039 Il2rg Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
Inhibitory Antibodies (11)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990281 Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) 95.00% Unkown
HY-P99902 Simlukafusp alfa Inhibitor 99.90% Unkown
HY-P990219 Anti-Mouse IL-2 Antibody (JES6-1A12) Inhibitor 95.00% Unkown
HY-P99680 Keliximab Inhibitor 98.23% Unkown
HY-P990086 Vopikitug Inhibitor / Unkown
HY-P991000 Imneskibart Inhibitor / Unkown
HY-P990796 Anti-Mouse IL-2 Antibody (S4B6-1) Inhibitor / Unkown
HY-P991214 Tucotuzumab celmoleukin Activator / Unkown
HY-P990736 Efercoleukin alfa / Unkown
HY-P991119 Balekafusp alfa Inhibitor / Unkown
HY-P991201 REGN-7257 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens IL2 NCBI NCBI:3558
Canis familiaris IL2 NCBI NCBI:403989
Macaca fascicularis IL2 NCBI NCBI:102129830
Mus musculus IL2 NCBI NCBI:16183
Susscrofa domestica IL2 NCBI
Leporidae IL2 NCBI
Rattus norvegicus IL2 NCBI NCBI:116562
Macaca mulatta IL2 NCBI NCBI:708017