2. Gene
  3. IL2 - interleukin 2 Gene

IL2 - interleukin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Bos taurus

Also known as IL-2; TCGF

Gene ID: 280822 | Gene type: protein coding

About IL2

Primary_assembly 17: 35,217,965-35,222,747 forward strand.ARS-UCD1.2:CM008184.2

This gene has 1 transcript (splice variant) and 89 orthologues.

IL2 Products(1)

mRNA Protein Name
NM_180997.2 NP_851340.2 interleukin-2 precursor

IL2 Protein Structure

IL2

IL2: smart00189 (0 - 154)

  • 0
  • 100
  • 155 a.a.
Protein Preferred Names Protein Names

interleukin-2

T-cell growth factor

interleukin2

Related Agents

Approval
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13756 Tacrolimus 99.93% Unkown
HY-A0003 Lenalidomide Inducer 99.94% Yes
HY-100754 Ritlecitinib Inhibitor 99.80% Yes
HY-B1046 Clofazimine 99.79% Unkown
HY-13756A Tacrolimus monohydrate 99.93% Yes
HY-A0003B Lenalidomide hemihydrate Inducer 99.98% Yes
HY-B0072 Tropisetron 99.93% Unkown
HY-B0199A Mycophenolate mofetil hydrochloride Inhibitor 99.17% Yes
HY-100754C Ritlecitinib tosylate Inhibitor 99.65% Yes
HY-B0199R Mycophenolate Mofetil (Standard) Inhibitor 99.86% Unkown
HY-A0003A Lenalidomide hydrochloride / Unkown
HY-100754A Ritlecitinib malonate Inhibitor / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108738 Daclizumab ≥99.0% Unkown
Clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Phase
HY-Y0344D Sodium chloride, for cell culture Activator 99.9% Phase 4
HY-Y0344J Sodium chloride, for molecular biology 99.97% Phase 4
HY-126404 Casein hydrolysate / Phase 4
HY-Y0344I Sodium chloride, meets analytical specification of Ph. Eur. BP USP, ≤0.00002% Al 99.99% Phase 4
HY-113271 5-Androstenetriol Activator / Phase 4
HY-Y0344H Sodium chloride, United States Pharmacopeia (USP) Reference Standard / Phase 4
HY-111167 AN-2898 Inhibitor / Phase 2
HY-137131 DC-Chol hydrochloride 99.95% Phase 1
HY-132304 CC-90005 Inhibitor 99.11% Phase 1
HY-173006 AZ3246 98.92% Phase 1
Inhibitory Antibodies (15)
Cat. No. Product Name Effect
Purity Phase
HY-P991028 Surovatamig Inhibitor 99.89% Phase 3
HY-P99943 Erfonrilimab 99.98% Phase 3
HY-P991214 Tucotuzumab celmoleukin 98.797% Phase 3
HY-P99499 Cetrelimab ≥99.0% Phase 3
HY-P99664 Inolimomab Inhibitor 98.78% Phase 3
HY-P99159 Ivuxolimab Activator ≥99.0% Phase 2
HY-P99410 Ordesekimab Inhibitor 99.08% Phase 2
HY-P99752 Nemvaleukin alfa 99.50% Phase 2
HY-P99328 Tucotuzumab 99% Phase 2
HY-P99728 Melredableukin alfa 96.22% Phase 2
HY-P991000 Imneskibart Inhibitor 99.0% Phase 2
HY-P990716 Sabestomig Inhibitor 98.33% Phase 2
HY-P99479 Bifikafusp alfa Inhibitor 96% Phase 2
HY-P991201 REGN-7257 Inhibitor 95.34% Phase 1
HY-P99498 Cergutuzumab amunaleukin Inhibitor 99.5% Phase 1
Pre-clinical Phase
Bioactive Molecules (169)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-153220 Zelebrudomide Inhibitor 99.72% Unkown
HY-126370A Geranylgeranyl pyrophosphate triammonium ≥95.0% Unkown
HY-122542B PPACK TFA 99.80% Unkown
HY-131140 BD750 Inhibitor 99.02% Unkown
HY-110117 BIRT 377 Inhibitor 99.82% Unkown
HY-N6607 Tryptanthrin 99.89% Unkown
HY-136339 Cbl-b-IN-1 Inhibitor 99.66% Unkown
HY-133987 AP-1/NF-κB activation inhibitor 1 Inhibitor 98.08% Unkown
HY-18303 AMG-47a Inhibitor 99.19% Unkown
HY-110177 SP-100030 Inhibitor 99.57% Unkown
HY-113494 Sitostanol Activator 99.0% Unkown
HY-P1997 Ferrichrome Iron-free 98.5% Unkown
HY-138568 HPK1-IN-3 Inhibitor 98.61% Unkown
HY-100712 DPO-1 Inhibitor 98.39% Unkown
HY-159647 PLX-4545 96.76% Unkown
HY-N6939 Pseudolaric Acid B 99.47% Unkown
HY-113618B RO2959 monohydrochloride Inhibitor 98.19% Unkown
HY-13756S Tacrolimus-13C,d2 98.36% Unkown
HY-N0534 Vitexin-2"-O-rhamnoside 99.78% Unkown
HY-126328 PKC-theta inhibitor 1 Inhibitor 99.45% Unkown
HY-N4087 Platycodin D2 Inducer 99.84% Unkown
HY-171034 PQA-18 Inhibitor 99.62% Unkown
HY-N0594 Deacetylasperulosidic Acid 99.44% Unkown
HY-121638A (5Z,2E)-CU-3 95.03% Unkown
HY-122542A PPACK dihydrochloride 99.07% Unkown
HY-119424 SP4206 Inhibitor 96.97% Unkown
HY-N0600 Ginsenoside F3 99.84% Unkown
HY-134820 MLT-943 Inhibitor 99.71% Unkown
HY-106755 Tucaresol Inhibitor 97.50% Unkown
HY-P3143 BMSpep-57 Inhibitor 99.87% Unkown
HY-W722277A LCC-12 formate Inhibitor 99.9% Unkown
HY-P1453A CMD178 TFA Inhibitor 99.71% Unkown
HY-B0199S Mycophenolate Mofetil-d4 Inhibitor 99.80% Unkown
HY-164756 PKCTheta-IN-2 Inhibitor 99.49% Unkown
HY-N2571 Corydine 99.93% Unkown
HY-100849 JAK 3i Inhibitor 99.81% Unkown
HY-149056 GNE-6893 Inhibitor 99.94% Unkown
HY-150051 IL-2-IN-1 Inhibitor 99.95% Unkown
HY-161389 SP-alkyne Inhibitor / Unkown
HY-21293 SU5201 Inhibitor 99.45% Unkown
HY-112778 NFAT Transcription Factor Regulator-1 Inhibitor 99.37% Unkown
HY-113618A RO2959 hydrochloride Inhibitor / Unkown
HY-121638 CU-3 / Unkown
HY-135078 2,5-Deoxyfructosazine Inhibitor 98.05% Unkown
HY-175547 PROTAC HPK1 Degrader-5 / Unkown
HY-A0003S Lenalidomide-d5 Inducer 99.32% Unkown
HY-P3143A BMSpep-57 hydrochloride Inhibitor 99.69% Unkown
HY-RS06749 IL2RB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06750 IL2RG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W048444 Diaminobiotin 99.9% Unkown
HY-Z8754 Tacrolimus 8-epimer 96.64% Unkown
HY-149917 ITK degrader 1 Degrader / Unkown
HY-P1453 CMD178 Inhibitor / Unkown
HY-103390 Ro26-4550 TFA Antagonist / Unkown
HY-108161 LF 1695 Activator / Unkown
HY-110113 CTA056 Inhibitor / Unkown
HY-112335 Lck Inhibitor III Inhibitor / Unkown
HY-112448 Lck-IN-6 Inhibitor / Unkown
HY-113494R Sitostanol (Standard) Activator / Unkown
HY-114980 BMS-279700 Inhibitor / Unkown
HY-115464 NC1153 / Unkown
HY-115756 4-Maleimidosalicylic acid / Unkown
HY-117843 Ppc-1 / Unkown
HY-120457 WYE-151650 Inhibitor / Unkown
HY-121743 Ro26-4550 Antagonist / Unkown
HY-121874 EP009 Inhibitor / Unkown
HY-123221 RS-0481 Activator / Unkown
HY-124665 LMP-420 / Unkown
HY-126370 Geranylgeranyl pyrophosphate / Unkown
HY-132304A (1S,4R)-CC-90005 Control 99.95% Unkown
HY-141864 ITK/TRKA-IN-1 Inhibitor / Unkown
HY-145675A (R)-TCB2 / Unkown
HY-147504 Anticancer agent 63 / Unkown
HY-149206 HPK1-IN-33 Inhibitor / Unkown
HY-149232 HPK1-IN-35 Inhibitor / Unkown
HY-149916 A2AR-antagonist-1 Antagonist 96.68% Unkown
HY-153952 Immuno modulator-1 Inhibitor / Unkown
HY-156149 CYP51/PD-L1-IN-1 Inhibitor / Unkown
HY-156150 CYP51/PD-L1-IN-2 Inhibitor / Unkown
HY-156151 CYP51/PD-L1-IN-3 Inhibitor / Unkown
HY-157569 PD1-PDL1-IN 2 / Unkown
HY-157838 HMC-B17 Inhibitor / Unkown
HY-159892 PD-1/PD-L1-IN-54 / Unkown
HY-159902 KRN7000 analog 3 Activator / Unkown
HY-161390 SPC-alkyne Inhibitor / Unkown
HY-163194 Cbl-b-IN-16 Inhibitor / Unkown
HY-163496 HPK1-IN-45 Inhibitor / Unkown
HY-16362 Omtriptolide sodium / Unkown
HY-163747 VEGFR-2-IN-47 Inhibitor / Unkown
HY-163849 Mizoribine prodrug-1 Inhibitor / Unkown
HY-163850 Mizoribine prodrug-2 trifluoroacetate Inhibitor / Unkown
HY-168282 DD205-291 Degrader / Unkown
HY-168963 PROTAC BTK Degrader-13 / Unkown
HY-169317 DGKζ-IN-6 Inhibitor / Unkown
HY-169318 DGKζ-IN-7 Inhibitor / Unkown
HY-172107 HPK1-IN-56 / Unkown
HY-172594 HPK1-IN-57 / Unkown
HY-172875 HPK1-IN-58 / Unkown
HY-173311 Cbl-b-IN-28 / Unkown
HY-173601 JAK3-IN-17 Inhibitor / Unkown
HY-174132 CW8001 Inhibitor / Unkown
HY-175195 Adenosine receptor antagonist 6 / Unkown
HY-175780 CD28-IN-1 Inhibitor / Unkown
HY-178062 DGKα-IN-10 / Unkown
HY-179111 HPK1-IN-64 Inhibitor / Unkown
HY-179338 HPK1-IN-65 / Unkown
HY-179575 Cbl-b-IN-29 / Unkown
HY-179617 Cbl-b-IN-30 Inhibitor / Unkown
HY-179727 PROTAC HPK1 Degrader-7 Activator / Unkown
HY-180608 TCR-IN-1 Inhibitor / Unkown
HY-180609 TCR-IN-2 Inhibitor / Unkown
HY-181924 HPK1-IN-68 / Unkown
HY-182238 HPK1-IN-69 / Unkown
HY-182369 VA06 Inhibitor / Unkown
HY-182765 VAV1 degrader-4 / Unkown
HY-182795 Colchicine derivative-1 / Unkown
HY-182799 IBA-12 Degrader / Unkown
HY-182945 IKZF2-degrader 5 / Unkown
HY-183317 IDO1-IN-34 / Unkown
HY-183539 INCB191358 Inhibitor / Unkown
HY-19009B Propagermanium Inhibitor / Unkown
HY-A0003S2 Lenalidomide-13C5,15N Inducer / Unkown
HY-B0199AS Mycophenolate Mofetil-d4 hydrochloride Inhibitor / Unkown
HY-N12988 Dihydrobonducellin Inhibitor / Unkown
HY-N16431 NFAT-133 / Unkown
HY-N1726 cis-Burchellin Inhibitor / Unkown
HY-N19727 Chamissonolide Inhibitor / Unkown
HY-N19872 Mukurozioside IIb / Unkown
HY-N19873 Mukurozioside IIa / Unkown
HY-P10544 Humanized anti-tac (HAT) binding peptide Inhibitor / Unkown
HY-P10994 Eps8 peptide 327 / Unkown
HY-P10995 TAT-327 / Unkown
HY-P11298 d-T101 peptide Activator / Unkown
HY-P3083 N-Myristoyl-Lys-Arg-Thr-Leu-Arg Inhibitor / Unkown
HY-P3736 Myelopeptide-2 Inducer / Unkown
HY-P5870 KTX-Sp2 Inhibitor / Unkown
HY-RS06728 IL2 Human Pre-designed siRNA Set A / Unkown
HY-RS06729 Il2 Mouse Pre-designed siRNA Set A / Unkown
HY-RS06730 Il2 Rat Pre-designed siRNA Set A / Unkown
HY-RS06748 IL2RA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W761985 Furathiocarb / Unkown
HY-W777675 2,5-Deoxyfructosazine-13C4 / Unkown
HY-101687 Nosantine racemate / Unkown
HY-123187 AS2553627 Inhibitor / Unkown
HY-123590 BC12-4 Inhibitor / Unkown
HY-132243 NFAT Inhibitor-3 Inhibitor / Unkown
HY-13644 Gusperimus / Unkown
HY-13756S2 Tacrolimus-d3 / Unkown
HY-161335 HPK1-IN-43 / Unkown
HY-163902 SP100030 analogue 1 Inhibitor / Unkown
HY-170616 JH-FK-08 Inhibitor / Unkown
HY-171004 KRN7000 analog 8 / Unkown
HY-173077 PD-L1/LpxC-IN-1 Inhibitor / Unkown
HY-174611 Human IL2RA mRNA / Unkown
HY-174625 Human IL2 mRNA 92.6% Unkown
HY-177058 DSP30 Agonist 95.27% Unkown
HY-181507 CD28-IN-3 Inhibitor / Unkown
HY-181821 MMV1581361 Inhibitor / Unkown
HY-A0003S3 Lenalidomide-d4 Inducer / Unkown
HY-B0757 Vitamin E nicotinate Inhibitor / Unkown
HY-N0594R Deacetylasperulosidic Acid (Standard) / Unkown
HY-N12783 Digitoxigenin-3-O-β-D-quinovoside Inhibitor / Unkown
HY-N15307 Trigraecum Inhibitor / Unkown
HY-RS16278 Il2rb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17342 Il2rb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18825 Il2ra Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20039 Il2rg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25315 Il2ra Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26542 Il2rg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (39)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P990864 Anti-CD3 Antibody (OKT-3) Inhibitor 95.00% Unkown
HY-P990281 Anti-Mouse CD25/IL-2Rα Antibody (PC-61.5.3) 99% Unkown
HY-P990219 Anti-Mouse IL-2 Antibody (JES6-1A12) Inhibitor 99% Unkown
HY-P991740 IBI-363 Inhibitor 99.60% Unkown
HY-P99877 Efavaleukin alfa ≥99.0% Unkown
HY-P990086 Vopikitug Inhibitor 98.32% Unkown
HY-P990736 Efercoleukin alfa 99.9% Unkown
HY-P99902 Simlukafusp alfa Inhibitor 99.90% Unkown
HY-P991279 Mik-Beta-1 Inhibitor ≥99.0% Unkown
HY-P990796 Anti-Mouse IL-2 Antibody (S4B6-1) Inhibitor 96.97% Unkown
HY-P991828 Anti-Mouse IL-2 Antibody (JES6-5H4) Inhibitor 98.62% Unkown
HY-P99680 Keliximab Inhibitor 98.23% Unkown
HY-P991119 Balekafusp alfa Inhibitor / Unkown
HY-P991999 OM-RCA-01 ≥99.0% Unkown
HY-P990808 Anti-Mouse CD122/IL-2Rβ Antibody (TM-Beta 1) Inhibitor 95% Unkown
HY-P991208 Flt-3L-Ig (hum/hum) 98% Unkown
HY-P992030 FB102 / Unkown
HY-P990986 Efdelikofusp alfa / Unkown
HY-P990992 Efzilonkofusp alfa / Unkown
HY-P990292 Anti-Mouse CD132 (common γ chain) Antibody (3E12) Inhibitor / Unkown
HY-P991270 MT204 Inhibitor / Unkown
HY-P991353 Sym-021 Antagonist / Unkown
HY-P991393 ASP8374 / Unkown
HY-P991566 KD6001 Inhibitor / Unkown
HY-P991634 IBI-325 Inhibitor / Unkown
HY-P991678 Efpixileukin alfa / Unkown
HY-P991696 Lecomkafusp alfa / Unkown
HY-P991749 Anti-Rat CD25 Antibody (OX-39) Inhibitor / Unkown
HY-P991762 Anti-Rat CD4 Antibody (W3/25) Inhibitor / Unkown
HY-P991960 JS007 / Unkown
HY-P992029 RTX-003 / Unkown
HY-P992031 Anti-IL-2R gamma Antibody Inhibitor / Unkown
HY-P992074 Zemlikafusp alfa Ligand / Unkown
HY-P992109 Eftezirleukin alfa / Unkown
HY-P992161 REGN-10597 / Unkown
HY-P992370 HPN601 Inhibitor / Unkown
HY-P992401 M802 / Unkown
HY-P990293 Anti-Mouse CD122/IL-2Rβ Antibody (5H4) Inhibitor ≥95.0% Unkown
HY-P990866 Anti-CD25/IL-2Rα Antibody (7G7B6) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens IL2 NCBI NCBI:3558
Canis familiaris IL2 NCBI NCBI:403989
Macaca fascicularis IL2 NCBI NCBI:102129830
Mus musculus IL2 NCBI NCBI:16183
Susscrofa domestica IL2 NCBI
Leporidae IL2 NCBI
Rattus norvegicus IL2 NCBI NCBI:116562
Macaca mulatta IL2 NCBI NCBI:708017