Fes - feline sarcoma oncogene Gene

Also Known as FPS; c-fes

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14159

Summary

Enables microtubule binding activity and protein kinase activity. Acts upstream of or within centrosome cycle and microtubule bundle formation. Located in microtubule Cytoskeleton. Is expressed in central nervous system and retina. Orthologous to human FES (FES proto-oncogene, tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Fes Products (1)

mRNA Protein Name
NM_010194.2 NP_034324.2 tyrosine-protein kinase Fes/Fps

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables microtubule binding IDA
IDA: Inferred from direct assay
14551201 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
22522491 MGI
enables protein kinase activity IDA
IDA: Inferred from direct assay
12192036 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within centrosome cycle IMP
IMP: Inferred from mutant phenotype
14551201 MGI
acts upstream of or within microtubule bundle formation IDA
IDA: Inferred from direct assay
14551201 MGI
Cellular Component GO Annotation Evidence References Source
located in microtubule cytoskeleton IDA
IDA: Inferred from direct assay
14551201 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tyrosine-protein kinase Fes/Fps

  • proto-oncogene c-Fes

  • proto-oncogene tyrosine-protein kinase Fes/Fps

  • tyrosine kinase Fps/Fes

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0988 Deferoxamine mesylate 99.86% Unkown
HY-B1625 Deferoxamine 99.76% Yes
HY-16168A Degarelix 99.96% Unkown
HY-107928 Iron dextran / Unkown
HY-B1306 4-Aminohippuric acid 99.84% Unkown
HY-16564 Deferasirox (Fe3+ chelate) Inhibitor 98.0% Unkown
HY-108017 Ferric maltol 99.93% Unkown
HY-16168 Degarelix acetate Antagonist 99.67% Unkown
HY-16168B Degarelix acetate hydrate / Unkown
HY-17609C Difelikefalin acetate Agonist / Unkown

Clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Phase
HY-12040 Elesclomol 99.43% Phase 3
HY-P1714 Apraglutide 99.90% Phase 3
HY-105239 Selepressin Agonist 98.17% Phase 3
HY-105239A Selepressin acetate Agonist 98.04% Phase 3
HY-P1714A Apraglutide TFA 98.69% Phase 3
HY-122844 Ifebemtinib Inhibitor 99.86% Phase 2
HY-P3516 Barusiban Antagonist / Phase 2

Pre-clinical Phase

Bioactive Molecules (167)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-D1533 RhoNox-1 98.54% Unkown
HY-W004544 o-Phenanthroline Inhibitor 99.96% Unkown
HY-D1913 Fe2Orange 98.2% Unkown
HY-137805 Ferrozine 99.96% Unkown
HY-N0928 Mimosine Inducer 99.97% Unkown
HY-128525 Enterobactin Inhibitor 99.64% Unkown
HY-W075707 FeTCPP chloride 95.0% Unkown
HY-145157 Ferric nitrilotriacetate 98.0% Unkown
HY-N10473 Pulcherriminic acid Inhibitor 98.0% Unkown
HY-D2295 Mito-FerroGreen 97.30% Unkown
HY-D0221 2,4,6-Tri-2-pyridinyl-1,3,5-triazine 99.87% Unkown
HY-Y1841 o-Phenanthroline monohydrate Inhibitor 99.95% Unkown
HY-126823 Phen Green SK diacetate (5/6-mixture) 92.99% Unkown
HY-163897 PROTAC NCOA4 degrader-1 Inhibitor 99.75% Unkown
HY-N10470 Bleomycin A5 99.81% Unkown
HY-132989 Mal-Deferoxamine 95.0% Unkown
HY-P3267A Apo-Bovine Transferrin Activator 95.2% Unkown
HY-156418 KY386 99.86% Unkown
HY-D0945 Xylene Cyanol FF 94.69% Unkown
HY-107928B Iron–Dextran(Fe 35-40% w/w) / Unkown
HY-W010323 2,5-Dihydroxy-1,4-benzoquinone Inhibitor 99.95% Unkown
HY-158739 Rhodamine dithenoyl hydrazide 98.00% Unkown
HY-DY1030 RhoNox-1 (solution) / Unkown
HY-W015600 2-Acetamidophenol 99.73% Unkown
HY-W075508 MIL-100(Fe) ≥98.0% Unkown
HY-158779 Sulfane sulfur probe 4 97.3% Unkown
HY-Y1422I Lipase,Pseudomonas fluorescens (Immobilized) / Unkown
HY-D2339 H-FluNox 99.53% Unkown
HY-W698249 Ferrous gluconate 99.25% Unkown
HY-160238 Bacillibactin Inhibitor 98.1% Unkown
HY-Y0102 Thiosalicylic acid 99.28% Unkown
HY-136300 PHD-1-IN-1 Inhibitor 99.21% Unkown
HY-W019888 Iron(II) chloride 99.99% Unkown
HY-W151629A Ferrozine sodium hydrate 99.80% Unkown
HY-145286 IMPDH2-IN-2 99.89% Unkown
HY-178364 GPX4-IN-19 99.45% Unkown
HY-B1250 Acedoben 99.68% Unkown
HY-P2777 Ceruloplasmin / Unkown
HY-W067445 N-(4-Formylphenyl)acetamide 99.68% Unkown
HY-B1159S Nitroxoline-d4 99.7% Unkown
HY-B1250A Acedoben sodium 99.99% Unkown
HY-N0046 Notoginsenoside Fe Inhibitor 99.99% Unkown
HY-W011816 1,2-Hexadecanediol 99.73% Unkown
HY-W015600S 2-Acetamidophenol-d3 99.48% Unkown
HY-W134005 Mg(Ⅱ)-EDTA disodium tetrahydrate 99.16% Unkown
HY-155539 Cisd2 agonist 2 Agonist 99.17% Unkown
HY-156776 HAPSBC ≥95.0% Unkown
HY-W249602 MIL-88A(Fe) / Unkown
HY-W112939 Fe(III)(TDCPP) chloride 95.00% Unkown
HY-160414 TRX-COBI Inhibitor / Unkown
HY-B1306S 4-Aminohippuric acid-d4 98.6% Unkown
HY-W107177 5,10,15,20-tetrakis(p-chlorophenyl)porphyrin iron(III) chloride 95.00% Unkown
HY-W112021 2,5-DMBQ 99.99% Unkown
HY-W113011 5,​10,​15,​20-​Tetra(4-​methylphenyl)​-​21H,​23H-​porphine iron(III) chloride / Unkown
HY-W124354 MIL-101-Fe / Unkown
HY-W718262 Dihydroaeruginoic acid / Unkown
HY-Y1422E Lipase,Aspergillusniger (Immobilized) / Unkown
HY-N13871 Anguibactin Inhibitor / Unkown
HY-N18050 Petrobactin / Unkown
HY-125918 Bleomycin A5 hydrochloride / Unkown
HY-100332 CP 375 / Unkown
HY-115832 Ap44mSe / Unkown
HY-117478 FE-999024 Inhibitor / Unkown
HY-117710B AD-35 Inhibitor / Unkown
HY-12040S Elesclomol-d2 / Unkown
HY-133849 Aristoforin Inhibitor / Unkown
HY-138185 Collismycin A Inhibitor / Unkown
HY-143249 MtMetAP1-IN-1 Inhibitor / Unkown
HY-149151 Variegatic acid Inhibitor / Unkown
HY-149418 BChE/HDAC6-IN-2 Inhibitor / Unkown
HY-155158 Anticancer agent 147 Inducer / Unkown
HY-157917 Nitro-PAPS disodium dihydrate / Unkown
HY-157926 Nitroso-PSAP / Unkown
HY-159943 ROS151 Inhibitor / Unkown
HY-16168AS Degarelix-d7 Antagonist / Unkown
HY-16168AS1 Degarelix-d7 TFA / Unkown
HY-16168AS2 Degarelix-d7 TFA-1 / Unkown
HY-162812 H3R antagonist 4 Inhibitor / Unkown
HY-162933 AChE-IN-77 Inhibitor / Unkown
HY-165381 ZMC2 Inducer / Unkown
HY-170433 DefNEtTrp Inducer / Unkown
HY-172092 BG11 Inducer / Unkown
HY-174867 AY-4 Agonist / Unkown
HY-175698 Ferroptosis inducer-9 / Unkown
HY-175852 Ferroptosis inducer-11 / Unkown
HY-176212 Ferroptosis-IN-20 Inhibitor / Unkown
HY-17655 TBE56 Inhibitor / Unkown
HY-177506 FE100726 Agonist / Unkown
HY-177507 FE101120 Agonist / Unkown
HY-178370 Ferroptosis inducer-12 Inducer 96.32% Unkown
HY-179003 mTOR/GLS1-IN-1 / Unkown
HY-179016 Ferroptosis/apoptosis inducer-3 / Unkown
HY-180114 NSS-18 / Unkown
HY-181982 HJ03 / Unkown
HY-182300 FE 999011 / Unkown
HY-182578 Mimosinamine Inhibitor / Unkown
HY-183618 DW-229 Degrader / Unkown
HY-183760 AChE/BChE-IN-37 Inhibitor / Unkown
HY-186106 3-Deoxyanguibactin / Unkown
HY-186239 Azophloxine-1,7-disulfonate disodium / Unkown
HY-D2204 SHP1-IN-1 Inhibitor / Unkown
HY-D2730 N14G-Fe Inhibitor / Unkown
HY-D3377 HMRhoNox-M / Unkown
HY-DY1106 Ferrozine (solution) / Unkown
HY-E70311 1,3-specific lipase,Bacillus lanolin (Immobilized) / Unkown
HY-E70583 Recombinant Ten-Eleven Translocase / Unkown
HY-E70905 Taurine Dioxygenase, E. coli / Unkown
HY-E71077 (5R)-Carbapenem-3-carboxylate synthase / Unkown
HY-E71089 (R)-2-Methylmalate dehydratase / Unkown
HY-E71099 (R)-Dichlorprop dioxygenase 2-oxoglutarate / Unkown
HY-E71143 1,2-Dihydroxynaphthalene dioxygenase / Unkown
HY-E71221 α-D-Ribose 1-methylphosphonate 5-phosphate C-P-lyase / Unkown
HY-E71278 β-Carotene 15,15'-dioxygenase / Unkown
HY-E71279 β-Carotene 3-hydroxylase / Unkown
HY-E71332 γ-Butyrobetaine dioxygenase / Unkown
HY-E71337 γ-Glutamyl hercynylcysteine S-oxide synthase / Unkown
HY-N17362 Anhydroevoxine / Unkown
HY-P11424 Cyclo(GRGDSPA) Inhibitor / Unkown
HY-P11504 Fmoc-Lys-Gly-Dopa-OH / Unkown
HY-RS04867 FES Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W004544S o-Phenanthroline-d8 Inhibitor / Unkown
HY-W075620 NH2-MIL-88B(Fe) / Unkown
HY-W075622 NH2-MIL-53(Fe) / Unkown
HY-W075623 NH2-MIL-101(Fe) / Unkown
HY-W075625 MIL-88B(Fe) / Unkown
HY-W075630 Mil-53(Fe) / Unkown
HY-W249563 PCN-250(Fe2Co) / Unkown
HY-W249605 PCN-222 / Unkown
HY-W414357 2-Aminophenanthrene / Unkown
HY-W698271 Ferrous lactate trihydrate / Unkown
HY-W747297 β-Selinene Inhibitor / Unkown
HY-W747910A S584 dihydrochloride / Unkown
HY-138075 Obafluorin Inhibitor 99.9% Unkown
HY-148340 24RBPyBC / Unkown
HY-153217 Arsonic acid / Unkown
HY-153512 PHD-1-IN-3 Inhibitor / Unkown
HY-17609S Difelikefalin-d5 Agonist / Unkown
HY-179102 SARS-CoV-2 Mpro-IN-51 Inhibitor / Unkown
HY-180223 FXIa-IN-17 Inhibitor / Unkown
HY-184620 Fe3O4 nanoparticle / Unkown
HY-184625 PEI coated Fe3O4 nanoparticles / Unkown
HY-184627 Carboxylated dextran coated Fe3O4 nanoparticles / Unkown
HY-184629 Ultra small magnetic Fe3O4 nanoparticles / Unkown
HY-184630 PLL coated Fe3O4 nanoparticles / Unkown
HY-184631 Carboxymethyldextran modified Fe3O4 nanoparticles / Unkown
HY-184632 Fe3O4 nanorods / Unkown
HY-184633 Hollow mesoporous Fe3O4 nanoparticles / Unkown
HY-184634 OA Coated Fe3O4 Nanoparticles / Unkown
HY-184635 Monodisperse Fe3O4 microspheres / Unkown
HY-184636 PLL coated Fe2O3 nanoparticles / Unkown
HY-184637 DMSA Coated Fe2O3 Nanoparticles / Unkown
HY-184638 APTS Fe2O3 Nanoparticles / Unkown
HY-184639 Carboxylated magnetic microspheres (low non-specificity) / Unkown
HY-184640 Carboxylated magnetic microspheres / Unkown
HY-184643 Mn-Zn Ferrite Nanoparticles / Unkown
HY-184647 Citrate-modified ferric oxide nanoparticles / Unkown
HY-185401 ATSM / Unkown
HY-N14059 Halymecin B / Unkown
HY-N14060 Halymecin C / Unkown
HY-N15282 Broussoflavonol G / Unkown
HY-RS18447 Fes Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24929 Fes Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W008952 Tributyltetradecyl phosphonium chloride / Unkown
HY-W009022 Diantipyrylmethane 98.98% Unkown
HY-W094110 Iron(III) sulfate / Unkown
HY-W130303 Diacetamide / Unkown
HY-W722245 Pyochelin / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fes NCBI NCBI:2242