Fes - feline sarcoma oncogene Gene
Also Known as FPS; c-fes
Species: Mus musculus
Gene Type: protein coding
Gene ID: 14159
Summary
Enables microtubule binding activity and protein kinase activity. Acts upstream of or within centrosome cycle and microtubule bundle formation. Located in microtubule Cytoskeleton. Is expressed in central nervous system and retina. Orthologous to human FES (FES proto-oncogene, tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]
Fes Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_010194.2 | NP_034324.2 | tyrosine-protein kinase Fes/Fps |
| Molecular Function GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| enables microtubule binding |
IDA
IDA: Inferred from direct assay
|
14551201 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
22522491 | MGI |
| enables protein kinase activity |
IDA
IDA: Inferred from direct assay
|
12192036 | MGI |
| Biological Process GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| acts upstream of or within centrosome cycle |
IMP
IMP: Inferred from mutant phenotype
|
14551201 | MGI |
| acts upstream of or within microtubule bundle formation |
IDA
IDA: Inferred from direct assay
|
14551201 | MGI |
| Cellular Component GO Annotation | Evidence | Verweise | Source |
|---|---|---|---|
| located in microtubule cytoskeleton |
IDA
IDA: Inferred from direct assay
|
14551201 | MGI |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
tyrosine-protein kinase Fes/Fps |
|
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(11)
| Art. -Nr. | Produktname |
Wirkung
|
Reinheit |
Rare Diseases
|
|---|---|---|---|---|
| HY-B0988 | Deferoxamine mesylate | 99.86% | Unkown | |
| HY-B1625 | Deferoxamine | 99.76% | Yes | |
| HY-16168A | Degarelix | 99.96% | Unkown | |
| HY-107928 | Iron dextran | / | Unkown | |
| HY-17609 | Difelikefalin | 99.98% | Unkown | |
| HY-B1306 | 4-Aminohippuric acid | 99.84% | Unkown | |
| HY-16564 | Deferasirox (Fe3+ chelate) | Inhibitor | 98.0% | Unkown |
| HY-108017 | Ferric maltol | 99.93% | Unkown | |
| HY-16168 | Degarelix acetate | Antagonist | 99.67% | Unkown |
| HY-16168B | Degarelix acetate hydrate | / | Unkown | |
| HY-17609C | Difelikefalin acetate | / | Unkown |
Clinical Phase
Bioactive Molecules
(5)
| Art. -Nr. | Produktname |
Wirkung
|
Reinheit |
Phase
|
|---|---|---|---|---|
| HY-125918 | Bleomycin A5 hydrochloride | / | Phase 4 | |
| HY-12040 | Elesclomol | 99.43% | Phase 3 | |
| HY-P1714 | Apraglutide | 99.90% | Phase 3 | |
| HY-105239A | Selepressin acetate | Agonist | 98.04% | Phase 3 |
| HY-P3516 | Barusiban | Antagonist | / | Phase 2 |
Pre-clinical Phase
Bioactive Molecules
(208)
| Art. -Nr. | Produktname |
Wirkung
|
Reinheit |
Rare Diseases
|
|---|---|---|---|---|
| HY-D1533 | RhoNox-1 | 98.54% | Unkown | |
| HY-W004544 | o-Phenanthroline | Inhibitor | 99.96% | Unkown |
| HY-D1913 | Fe2Orange | 98.2% | Unkown | |
| HY-137805 | Ferrozine | 99.96% | Unkown | |
| HY-122844 | Ifebemtinib | Inhibitor | 99.86% | Unkown |
| HY-N0928 | Mimosine | Inducer | 99.97% | Unkown |
| HY-128525 | Enterobactin | Inhibitor | 99.64% | Unkown |
| HY-W075707 | FeTCPP chloride | 95.0% | Unkown | |
| HY-145157 | Ferric nitrilotriacetate | 98.0% | Unkown | |
| HY-N10473 | Pulcherriminic acid | Inhibitor | 98.0% | Unkown |
| HY-D2295 | Mito-FerroGreen | 97.30% | Unkown | |
| HY-D0221 | 2,4,6-Tri-2-pyridinyl-1,3,5-triazine | 99.87% | Unkown | |
| HY-Y1841 | o-Phenanthroline monohydrate | Inhibitor | 99.95% | Unkown |
| HY-126823 | Phen Green SK diacetate (5/6-mixture) | 92.99% | Unkown | |
| HY-163897 | PROTAC NCOA4 degrader-1 | Inhibitor | 99.75% | Unkown |
| HY-N10470 | Bleomycin A5 | 99.81% | Unkown | |
| HY-P3267A | Apo-Bovine Transferrin | Activator | 95.0% | Unkown |
| HY-132989 | Mal-Deferoxamine | Inhibitor | 95.0% | Unkown |
| HY-W127790 | Bathophenanthrolinedisulfonic acid disodium | 98.0% | Unkown | |
| HY-156418 | KY386 | 99.86% | Unkown | |
| HY-D0945 | Xylene Cyanol FF | 94.69% | Unkown | |
| HY-P1997 | Ferrichrome Iron-free | 98.5% | Unkown | |
| HY-107928B | Iron–Dextran(Fe 35-40% w/w) | / | Unkown | |
| HY-W010323 | 2,5-Dihydroxy-1,4-benzoquinone | Inhibitor | 99.95% | Unkown |
| HY-W015600 | 2-Acetamidophenol | 99.73% | Unkown | |
| HY-W075508 | MIL-100(Fe) | ≥98.0% | Unkown | |
| HY-158739 | Rhodamine dithenoyl hydrazide | 98.00% | Unkown | |
| HY-DY1030 | RhoNox-1 (solution) | 94.95% | Unkown | |
| HY-105239 | Selepressin | Agonist | 98.17% | Unkown |
| HY-158779 | Sulfane sulfur probe 4 | 97.3% | Unkown | |
| HY-Y1422I | Lipase,Pseudomonas fluorescens (Immobilized) | / | Unkown | |
| HY-D2339 | H-FluNox | 99.53% | Unkown | |
| HY-W698249 | Ferrous gluconate | 99.25% | Unkown | |
| HY-160238 | Bacillibactin | Inhibitor | 98.1% | Unkown |
| HY-Y0102 | Thiosalicylic acid | 99.28% | Unkown | |
| HY-136300 | PHD-1-IN-1 | Inhibitor | 99.21% | Unkown |
| HY-W019888 | Iron(II) chloride | 99.99% | Unkown | |
| HY-W151629A | Ferrozine sodium hydrate | 99.80% | Unkown | |
| HY-145286 | IMPDH2-IN-2 | 99.89% | Unkown | |
| HY-178364 | GPX4-IN-19 | 99.45% | Unkown | |
| HY-B1250 | Acedoben | 99.68% | Unkown | |
| HY-P1714A | Apraglutide TFA | 98.69% | Unkown | |
| HY-P2777 | Ceruloplasmin | / | Unkown | |
| HY-W067445 | N-(4-Formylphenyl)acetamide | 99.68% | Unkown | |
| HY-B1159S | Nitroxoline-d4 | 99.7% | Unkown | |
| HY-B1250A | Acedoben sodium | 99.99% | Unkown | |
| HY-N0046 | Notoginsenoside Fe | Inhibitor | 99.99% | Unkown |
| HY-W011816 | 1,2-Hexadecanediol | 99.94% | Unkown | |
| HY-W015600S | 2-Acetamidophenol-d3 | 99.48% | Unkown | |
| HY-W134005 | Mg(Ⅱ)-EDTA disodium tetrahydrate | 99.16% | Unkown | |
| HY-W112939 | Fe(III)(TDCPP) chloride | 95.00% | Unkown | |
| HY-155539 | Cisd2 agonist 2 | Agonist | 99.17% | Unkown |
| HY-156776 | HAPSBC | ≥95.0% | Unkown | |
| HY-W249602 | MIL-88A(Fe) | / | Unkown | |
| HY-N18050 | Petrobactin | / | Unkown | |
| HY-17609S1 | Difelikefalin-d5 hydrochloride | 97.58% | Unkown | |
| HY-160414 | TRX-COBI | Inhibitor | / | Unkown |
| HY-B1306S | 4-Aminohippuric acid-d4 | 98.6% | Unkown | |
| HY-D3116 | RhoNox-4 | Inhibitor | 98.65% | Unkown |
| HY-W107177 | 5,10,15,20-tetrakis(p-chlorophenyl)porphyrin iron(III) chloride | 95.00% | Unkown | |
| HY-W112021 | 2,5-DMBQ | 99.99% | Unkown | |
| HY-W113011 | 5,10,15,20-Tetra(4-methylphenyl)-21H,23H-porphine iron(III) chloride | / | Unkown | |
| HY-W124354 | MIL-101-Fe | / | Unkown | |
| HY-W718262 | Dihydroaeruginoic acid | / | Unkown | |
| HY-Y1422E | Lipase,Aspergillusniger (Immobilized) | / | Unkown | |
| HY-N13871 | Anguibactin | Inhibitor | / | Unkown |
| HY-N2757 | 7-Ketositosterol | 99.90% | Unkown | |
| HY-W739372 | Poly(sodium 4-styrenesulfonate) | / | Unkown | |
| HY-100332 | CP 375 | / | Unkown | |
| HY-115832 | Ap44mSe | / | Unkown | |
| HY-117478 | FE-999024 | Inhibitor | / | Unkown |
| HY-12040S | Elesclomol-d2 | / | Unkown | |
| HY-133849 | Aristoforin | Inhibitor | / | Unkown |
| HY-138185 | Collismycin A | Inhibitor | / | Unkown |
| HY-143249 | MtMetAP1-IN-1 | Inhibitor | / | Unkown |
| HY-149151 | Variegatic acid | Inhibitor | / | Unkown |
| HY-149418 | BChE/HDAC6-IN-2 | Inhibitor | / | Unkown |
| HY-155158 | Anticancer agent 147 | Inducer | / | Unkown |
| HY-157917 | Nitro-PAPS disodium dihydrate | / | Unkown | |
| HY-157926 | Nitroso-PSAP | / | Unkown | |
| HY-159943 | ROS151 | Inhibitor | / | Unkown |
| HY-16168AS | Degarelix-d7 | Antagonist | / | Unkown |
| HY-16168AS1 | Degarelix-d7 TFA | / | Unkown | |
| HY-16168AS2 | Degarelix-d7 TFA-1 | / | Unkown | |
| HY-162812 | H3R antagonist 4 | Inhibitor | / | Unkown |
| HY-162933 | AChE-IN-77 | Inhibitor | / | Unkown |
| HY-165381 | ZMC2 | Inducer | / | Unkown |
| HY-170433 | DefNEtTrp | Inducer | / | Unkown |
| HY-172092 | BG11 | Inducer | / | Unkown |
| HY-174867 | AY-4 | Agonist | / | Unkown |
| HY-175698 | Ferroptosis inducer-9 | / | Unkown | |
| HY-175852 | Ferroptosis inducer-11 | / | Unkown | |
| HY-176212 | Ferroptosis-IN-20 | Inhibitor | / | Unkown |
| HY-17655 | TBE56 | Inhibitor | / | Unkown |
| HY-177506 | FE100726 | Agonist | / | Unkown |
| HY-177507 | FE101120 | Agonist | / | Unkown |
| HY-178370 | Ferroptosis inducer-12 | Inducer | 96.32% | Unkown |
| HY-179003 | mTOR/GLS1-IN-1 | / | Unkown | |
| HY-179016 | Ferroptosis/apoptosis inducer-3 | / | Unkown | |
| HY-180114 | NSS-18 | / | Unkown | |
| HY-181982 | HJ03 | / | Unkown | |
| HY-182300 | FE 999011 | / | Unkown | |
| HY-182578 | Mimosinamine | Inhibitor | / | Unkown |
| HY-183618 | DW-229 | Degrader | / | Unkown |
| HY-183760 | AChE/BChE-IN-37 | Inhibitor | / | Unkown |
| HY-186106 | 3-Deoxyanguibactin | / | Unkown | |
| HY-186239 | Azophloxine-1,7-disulfonate disodium | / | Unkown | |
| HY-187209 | SGC stimulator 2 | / | Unkown | |
| HY-D2204 | SHP1-IN-1 | Inhibitor | / | Unkown |
| HY-D2730 | N14G-Fe | Inhibitor | / | Unkown |
| HY-D3377 | HMRhoNox-M | / | Unkown | |
| HY-DY1106 | Ferrozine (solution) | / | Unkown | |
| HY-E70311 | 1,3-specific lipase,Bacillus lanolin (Immobilized) | / | Unkown | |
| HY-E70583 | Recombinant Ten-Eleven Translocase | / | Unkown | |
| HY-E70905 | Taurine Dioxygenase, E. coli | / | Unkown | |
| HY-E71077 | (5R)-Carbapenem-3-carboxylate synthase | / | Unkown | |
| HY-E71089 | (R)-2-Methylmalate dehydratase | / | Unkown | |
| HY-E71099 | (R)-Dichlorprop dioxygenase 2-oxoglutarate | / | Unkown | |
| HY-E71143 | 1,2-Dihydroxynaphthalene dioxygenase | / | Unkown | |
| HY-E71221 | α-D-Ribose 1-methylphosphonate 5-phosphate C-P-lyase | / | Unkown | |
| HY-E71278 | β-Carotene 15,15'-dioxygenase | / | Unkown | |
| HY-E71279 | β-Carotene 3-hydroxylase | / | Unkown | |
| HY-E71332 | γ-Butyrobetaine dioxygenase | / | Unkown | |
| HY-E71337 | γ-Glutamyl hercynylcysteine S-oxide synthase | / | Unkown | |
| HY-E71386 | 1-Deoxypentalenic acid 11β-hydroxylase | / | Unkown | |
| HY-E71388 | 1-Hydroxy-2-naphthoate 1,2-dioxygenase | / | Unkown | |
| HY-E71402 | 2-(3-amino-3-carboxypropyl)Histidine synthase | / | Unkown | |
| HY-E71438 | 2,5-Dihydroxypyridine 5,6-dioxygenase | / | Unkown | |
| HY-E71439 | 2,5-Diketocamphane 1,2-monooxygenase | / | Unkown | |
| HY-E71453C | 23S rRNA (adenine2503-C2)-Methyltransferase | / | Unkown | |
| HY-E71453U | 23S rRNA (uracil1939-C5)-Methyltransferase | / | Unkown | |
| HY-E71468 | 2-Amino-1-hydroxyethylphosphonate dioxygenase (glycine-forming) | / | Unkown | |
| HY-E71479 | 2-Aminoethylphosphonate dioxygenase | / | Unkown | |
| HY-E71559 | 2-Hydroxyethylphosphonate dioxygenase | / | Unkown | |
| HY-E71575 | 2-Iminoacetate synthase | / | Unkown | |
| HY-E71602 | 2-Oxoacid oxidoreductase (ferredoxin) | / | Unkown | |
| HY-E71603 | 2-Oxo-acid reductase | / | Unkown | |
| HY-E71610 | 2-Oxoglutarate synthase | / | Unkown | |
| HY-E71707 | 3-Hydroxyanthranilate 3,4-dioxygenase | / | Unkown | |
| HY-E71824 | 4-Hydroxy-3-methylbut-2-en-1-yl diphosphate reductase | / | Unkown | |
| HY-E71837 | 4-Hydroxybenzoyl-CoA reductase | / | Unkown | |
| HY-E71859 | 4-Hydroxysphinganine ceramide fatty acyl 2-hydroxylase | / | Unkown | |
| HY-E71931 | 5-Methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase | / | Unkown | |
| HY-E71933 | 5-Methyltetrahydrosarcinapterin:corrinoid/iron-sulfur protein Co-methyltransferase | / | Unkown | |
| HY-E71958 | 6-Deoxyerythronolide B hydroxylase | / | Unkown | |
| HY-E71969 | 6-Hydroxynicotinate reductase | / | Unkown | |
| HY-E72006 | 7-Hydroxymethyl chlorophyll a reductase | / | Unkown | |
| HY-N17362 | Anhydroevoxine | / | Unkown | |
| HY-P11424 | Cyclo(GRGDSPA) | Inhibitor | / | Unkown |
| HY-P11504 | Fmoc-Lys-Gly-Dopa-OH | 99.34% | Unkown | |
| HY-P12123 | Malleobactin E | Activator | / | Unkown |
| HY-RS04867 | FES Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-W004544S | o-Phenanthroline-d8 | Inhibitor | / | Unkown |
| HY-W075620 | NH2-MIL-88B(Fe) | / | Unkown | |
| HY-W075622 | NH2-MIL-53(Fe) | / | Unkown | |
| HY-W075623 | NH2-MIL-101(Fe) | / | Unkown | |
| HY-W075625 | MIL-88B(Fe) | / | Unkown | |
| HY-W075630 | Mil-53(Fe) | / | Unkown | |
| HY-W127839 | EDTA dipotassium magnesium | / | Unkown | |
| HY-W249563 | PCN-250(Fe2Co) | / | Unkown | |
| HY-W249605 | PCN-222 | / | Unkown | |
| HY-W414357 | 2-Aminophenanthrene | / | Unkown | |
| HY-W698271 | Ferrous lactate trihydrate | / | Unkown | |
| HY-W747297 | β-Selinene | Inhibitor | / | Unkown |
| HY-W747910A | S584 dihydrochloride | / | Unkown | |
| HY-Y0850U1 | PVA (Mw 61000, 98-99% hydrolyzed, ~1400 polymerization) | / | Unkown | |
| HY-128073 | 5-(2-Nitrophenyl)-2-furoic acid | Inhibitor | / | Unkown |
| HY-128526 | Acinetobactin | / | Unkown | |
| HY-138075 | Obafluorin | Inhibitor | 99.9% | Unkown |
| HY-148340 | 24RBPyBC | / | Unkown | |
| HY-153217 | Arsonic acid | / | Unkown | |
| HY-153512 | PHD-1-IN-3 | Inhibitor | / | Unkown |
| HY-17609A | Difelikefalin hydrochloride | / | Unkown | |
| HY-17609S | Difelikefalin-d5 | / | Unkown | |
| HY-179102 | SARS-CoV-2 Mpro-IN-51 | Inhibitor | / | Unkown |
| HY-180223 | FXIa-IN-17 | Inhibitor | / | Unkown |
| HY-183524 | ICRF 192 | Inhibitor | / | Unkown |
| HY-184103 | ECDG | Inhibitor | / | Unkown |
| HY-184620 | Fe3O4 nanoparticle | / | Unkown | |
| HY-184625 | PEI coated Fe3O4 nanoparticles | / | Unkown | |
| HY-184627 | Carboxylated dextran coated Fe3O4 nanoparticles | / | Unkown | |
| HY-184629 | Ultra small magnetic Fe3O4 nanoparticles | / | Unkown | |
| HY-184630 | PLL coated Fe3O4 nanoparticles | / | Unkown | |
| HY-184631 | Carboxymethyldextran modified Fe3O4 nanoparticles | / | Unkown | |
| HY-184632 | Fe3O4 nanorods | / | Unkown | |
| HY-184633 | Hollow mesoporous Fe3O4 nanoparticles | / | Unkown | |
| HY-184634 | OA Coated Fe3O4 Nanoparticles | / | Unkown | |
| HY-184635 | Monodisperse Fe3O4 microspheres | / | Unkown | |
| HY-184636 | PLL coated Fe2O3 nanoparticles | / | Unkown | |
| HY-184637 | DMSA Coated Fe2O3 Nanoparticles | / | Unkown | |
| HY-184638 | APTS Fe2O3 Nanoparticles | / | Unkown | |
| HY-184639 | Carboxylated magnetic microspheres (low non-specificity) | / | Unkown | |
| HY-184640 | Carboxylated magnetic microspheres | / | Unkown | |
| HY-184643 | Mn-Zn Ferrite Nanoparticles | / | Unkown | |
| HY-184647 | Citrate-modified ferric oxide nanoparticles | / | Unkown | |
| HY-185401 | ATSM | / | Unkown | |
| HY-187378 | HPPD-IN-12 | Inhibitor | / | Unkown |
| HY-N14059 | Halymecin B | / | Unkown | |
| HY-N14060 | Halymecin C | / | Unkown | |
| HY-N15282 | Broussoflavonol G | / | Unkown | |
| HY-RS18447 | Fes Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24929 | Fes Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-W008952 | Tributyltetradecyl phosphonium chloride | / | Unkown | |
| HY-W009022 | Diantipyrylmethane | 98.98% | Unkown | |
| HY-W094110 | Iron(III) sulfate | / | Unkown | |
| HY-W130303 | Diacetamide | / | Unkown | |
| HY-W722245 | Pyochelin | / | Unkown | |
| HY-W989128 | Ethyl 8-hydroxy-α-(2-propynylamino) | / | Unkown |
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