BAX - BCL2 associated X, apoptosis regulator Gene
Species: Canis lupus familiaris (sub-species: familiaris)
Gene Type: protein coding
Gene ID: 403523
About BAX
Primary_assembly 1: 107,947,430-107,951,107 reverse strand.ROS_Cfam_1.0:CM025100.1
This gene has 2 transcripts (splice variants), 206 orthologues and 6 paralogues.
BAX Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001003011.1 | NP_001003011.1 | apoptosis regulator BAX |
BAX Protein Structure
bcl-2
bcl-2: TIGR00865 (4 - 191)
- 0
- 100
- 192 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
apoptosis regulator BAX |
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(6)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-B1192 | Estradiol benzoate | 99.90% | Unkown | |
| HY-B1357 | Digitoxin | 99.22% | Yes | |
| HY-B0402 | Amantadine | Modulator | 99.90% | Unkown |
| HY-B0402A | Amantadine hydrochloride | Modulator | 98.0% | Yes |
| HY-B0621 | Triclabendazole | 99.36% | Yes | |
| HY-B0402B | Amantadine sulfate | Modulator | / | Unkown |
Clinical Phase
Bioactive Molecules
(5)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-13755 | Sulforaphane | Inhibitor | 99.75% | Phase 4 |
| HY-13560 | AVN-944 | Modulator | 99.89% | Phase 2 |
| HY-18006 | NKP608 | Inhibitor | 99.88% | Phase 2 |
| HY-168739 | Topoisomerase I inhibitor 17 | Activator | / | Phase 2 |
| HY-165550 | Sphingosine | Inhibitor | / | Phase 1 |
Bioactive MoleculesInhibitory Antibodies
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-P991883 | Metuzumab | Modulator | / | Phase 4 |
Pre-clinical Phase
Bioactive Molecules
(162)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-107202 | Polyinosinic-polycytidylic acid | 99.40% | Unkown | |
| HY-N0171A | Beta-Sitosterol (purity>98%) | 99.74% | Unkown | |
| HY-103269 | BAI1 | Inhibitor | 99.54% | Unkown |
| HY-107202A | Poly (I:C):Kanamycin (1:1) | 48.6% | Unkown | |
| HY-P0081 | Bax inhibitor peptide V5 | Inhibitor | 99.90% | Unkown |
| HY-W250111 | Carboxymethyl chitosan | Activator | 90% | Unkown |
| HY-N0361 | Dihydrocapsaicin | Modulator | 99.93% | Unkown |
| HY-N0674 | Dehydrocorydaline | Modulator | 99.77% | Unkown |
| HY-B1971 | Deltamethrin | 99.93% | Unkown | |
| HY-120079 | MSN-125 | Inhibitor | 99.67% | Unkown |
| HY-13755A | (R)-Sulforaphane | Inhibitor | 99.95% | Unkown |
| HY-P1928 | Humanin | Inhibitor | 99.73% | Unkown |
| HY-N0060B | (E)-Ferulic acid | Activator | 99.82% | Unkown |
| HY-123054 | BTSA1 | Activator | 99.77% | Unkown |
| HY-N6626 | Pyraclostrobin | 99.91% | Unkown | |
| HY-157334 | DEG-77 | Activator | 99.03% | Unkown |
| HY-N0831 | Jaceosidin | Activator | 99.51% | Unkown |
| HY-118948 | MSN-50 | Inhibitor | 98.09% | Unkown |
| HY-126437 | Poly-L-lysine hydrobromide (MW 30000-70000) | Inhibitor | / | Unkown |
| HY-W082785A | L6H21 | Modulator | 99.19% | Unkown |
| HY-13108 | Bz 423 | Activator | 99.72% | Unkown |
| HY-P2970 | Stem bromelain | Modulator | / | Unkown |
| HY-N6005 | Methyl caffeate | Modulator | 99.89% | Unkown |
| HY-N2067 | Vanillyl alcohol | 99.68% | Unkown | |
| HY-P1380A | Difopein TFA | Inhibitor | 95.35% | Unkown |
| HY-N6801 | Nivalenol | Activator | 99.9% | Unkown |
| HY-N0475 | Triptophenolide | Activator | 99.98% | Unkown |
| HY-101310 | SYM 2081 | Activator | 98.0% | Unkown |
| HY-N0699 | Daphnoretin | Inhibitor | 99.83% | Unkown |
| HY-N0905 | Ginsenoside Rh4 | Activator | 99.28% | Unkown |
| HY-157176 | BAX-IN-1 | Inhibitor | 98.05% | Unkown |
| HY-N0566 | 23-Hydroxybetulinic acid | 99.44% | Unkown | |
| HY-N1983 | Caudatin | 99.95% | Unkown | |
| HY-N0307 | Ciwujianoside B | Inhibitor | 99.68% | Unkown |
| HY-N2135 | Puerarin 6''-O-Xyloside | 99.81% | Unkown | |
| HY-15341 | BAM7 | Activator | 99.20% | Unkown |
| HY-132173 | GL0388 | Activator | 98.03% | Unkown |
| HY-W674241 | 4-Ethylphenyl sulfate | / | Unkown | |
| HY-147929 | Apoptotic agent-3 | Activator | 98.19% | Unkown |
| HY-101996 | SMBA1 | Agonist | 99.5800% | Unkown |
| HY-N1157 | Thevetiaflavone | Modulator | 99.83% | Unkown |
| HY-N7905 | Myricetin 3'-glucoside | Inhibitor | 99.98% | Unkown |
| HY-148368 | CYD-4-61 | Activator | 99.92% | Unkown |
| HY-147785 | Pim-1 kinase inhibitor 2 | Modulator | 99.91% | Unkown |
| HY-172262 | WEHI-3773 | Inhibitor | 99.89% | Unkown |
| HY-N1423B | Glycocholic acid hydrate | Modulator | 99.85% | Unkown |
| HY-N0320 | Salvianolic acid D | Modulator | 95.15% | Unkown |
| HY-N0882 | Desacetylcinobufotalin | Modulator | 99.41% | Unkown |
| HY-W072962 | WX2-43 | Activator | 98.74% | Unkown |
| HY-119979 | Cardanol monoene | 98.02% | Unkown | |
| HY-122760 | Bax activator-1 | Activator | 98.45% | Unkown |
| HY-108164 | Aspidin BB | Modulator | 98.02% | Unkown |
| HY-N9802 | n-Butyl-β-D-fructofuranoside | Activator | 97.0% | Unkown |
| HY-146548 | Anticancer agent 43 | Inducer | 98.58% | Unkown |
| HY-147889 | BBR-BODIPY | Activator | 98.15% | Unkown |
| HY-N10144 | Shinpterocarpin | / | Unkown | |
| HY-161659 | Apoptosis inducer 19 | Modulator | 98.31% | Unkown |
| HY-141876 | PRT543 | Activator | / | Unkown |
| HY-144791 | Bcl-2-IN-6 | Modulator | / | Unkown |
| HY-181248 | BChE-IN-49 | Inhibitor | / | Unkown |
| HY-184301 | EGFR/HER2-IN-20 | Activator | / | Unkown |
| HY-168877 | FMP | / | Unkown | |
| HY-181060 | Apoptosis inducer 56 | Modulator | / | Unkown |
| HY-181599 | XAN-5 | / | Unkown | |
| HY-N17816 | Tambulin | Inhibitor | / | Unkown |
| HY-179157 | MA203 | Modulator | / | Unkown |
| HY-N10313 | Dehydrobruceine B | Modulator | / | Unkown |
| HY-N8617 | Trijuganone C | Activator | / | Unkown |
| HY-N17440 | 2-Methoxyjuglone | Modulator | / | Unkown |
| HY-178104 | HDAC-IN-93 | Inhibitor | / | Unkown |
| HY-181019 | iMPZ-8 | / | Unkown | |
| HY-146253 | CDK1/2/4-IN-1 | Activator | / | Unkown |
| HY-180190 | Tubulin polymerization-IN-85 | / | Unkown | |
| HY-149517 | EGFR/BRAFV600E-IN-2 | Activator | / | Unkown |
| HY-151429 | Antitumor agent-77 | Inhibitor | / | Unkown |
| HY-175037 | DNH28 | Inhibitor | / | Unkown |
| HY-172886 | PI3K-IN-58 | Modulator | / | Unkown |
| HY-170912 | Topo I/II-IN-2 | / | Unkown | |
| HY-151428 | Antitumor agent-78 | Inhibitor | / | Unkown |
| HY-N12999 | Stigmast-5-en-3-ol | / | Unkown | |
| HY-147928 | Apoptotic agent-2 | Activator | / | Unkown |
| HY-180242 | EGFR/CDK2-IN-5 | Modulator | / | Unkown |
| HY-172394 | ZSNI-21 | Modulator | / | Unkown |
| HY-178942 | EGFR/VEGFR2-IN-9 | Inhibitor | / | Unkown |
| HY-181673 | ICD inducer-2 | / | Unkown | |
| HY-147514 | Anticancer agent 64 | Modulator | / | Unkown |
| HY-184116 | A2AR/EGFR-IN-1 | Modulator | / | Unkown |
| HY-183791A | Ferroptosis/apoptosis inducer-5 | Modulator | / | Unkown |
| HY-181659 | EGFR-IN-201 | Inhibitor | / | Unkown |
| HY-174855 | PI3K/mTOR-IN-17 | Inhibitor | / | Unkown |
| HY-184250 | FGFR-IN-28 | Modulator | / | Unkown |
| HY-N6799 | Neosolaniol | Activator | 99.72% | Unkown |
| HY-181061 | COX/5-LO-IN-2 | Modulator | / | Unkown |
| HY-143235 | BRD4 Inhibitor-15 | Modulator | / | Unkown |
| HY-183355 | KRAS G12D-IN-37 | / | Unkown | |
| HY-183369 | VEGFR/PD-L1-IN-1 | Activator | / | Unkown |
| HY-181477 | ERK5-IN-7 | Modulator | / | Unkown |
| HY-180150 | PROTAC BRD4 Degrader-42 | Activator | / | Unkown |
| HY-181717 | TKL002 | Inhibitor | / | Unkown |
| HY-P10992 | YVPGP | Modulator | / | Unkown |
| HY-182937 | FLC-8 | Modulator | / | Unkown |
| HY-180196 | EGFR-IN-187 | / | Unkown | |
| HY-178099 | Apoptosis inducer 45 | Inhibitor | / | Unkown |
| HY-P1380 | Difopein | Inhibitor | / | Unkown |
| HY-N1326 | Santamarine | 98.85% | Unkown | |
| HY-107272 | Chuanbeinone | / | Unkown | |
| HY-184145 | AKT1-IN-13 | Inhibitor | / | Unkown |
| HY-175019 | VEGFR-2-IN-70 | Agonist | / | Unkown |
| HY-180154 | EGFR/BRAFV600E-IN-6 | / | Unkown | |
| HY-179614 | PARP1-IN-50 | / | Unkown | |
| HY-175815 | Apoptosis inducer 44 | Inhibitor | / | Unkown |
| HY-175227 | STAT3/NF-κB-IN-1 | Inhibitor | / | Unkown |
| HY-126311 | 4-Hydroxyresveratrol | Inducer | / | Unkown |
| HY-117652 | Lobetyol | Modulator | / | Unkown |
| HY-179022 | CAIX/CDK-2-IN-1 | Inhibitor | / | Unkown |
| HY-175021 | HDAC-IN-91 | Inhibitor | / | Unkown |
| HY-183069 | FKL-137 | Modulator | / | Unkown |
| HY-183772 | TBC1D2-IN-1 | Modulator | / | Unkown |
| HY-144792 | Bcl-2-IN-7 | Modulator | / | Unkown |
| HY-179052 | Apoptosis inducer 50 | Activator | / | Unkown |
| HY-15668 | ST09 | Activator | / | Unkown |
| HY-175332 | Apoptosis inducer 43 | Inhibitor | / | Unkown |
| HY-180324 | Candidone | Inhibitor | / | Unkown |
| HY-136893 | SP-6-27 | Activator | / | Unkown |
| HY-167237 | Calactin | Modulator | / | Unkown |
| HY-177208 | BW-AQ-113 | / | Unkown | |
| HY-175020 | QNX-10 | / | Unkown | |
| HY-146105 | Anticancer agent 65 | Modulator | / | Unkown |
| HY-P10993 | CT20p | / | Unkown | |
| HY-P11374 | Bid BH3-Gly-r8 | Ligand | / | Unkown |
| HY-174419 | TFSeB | Activator | / | Unkown |
| HY-150540 | Bcl-2-IN-10 | Inhibitor | / | Unkown |
| HY-179520 | XSJ151 | Modulator | / | Unkown |
| HY-170929 | EMT inhibitor-3 | / | Unkown | |
| HY-182349 | Bax activator-2 | Activator | / | Unkown |
| HY-184448 | CIB-Q22 | Modulator | / | Unkown |
| HY-183330 | Topo I/II-IN-3 | Inhibitor | / | Unkown |
| HY-168623 | EGFR-IN-134 | Inhibitor | / | Unkown |
| HY-183312 | Antitumor agent-217 | Inhibitor | / | Unkown |
| HY-180274 | JAK1/2-IN-3 | / | Unkown | |
| HY-181015 | α-D-Manp(3→1)-α-D-Manp(2→1)-α-D-Glu | Modulator | / | Unkown |
| HY-162360 | EGFR-IN-109 | Inhibitor | / | Unkown |
| HY-181769 | Anticancer agent 306 | Modulator | / | Unkown |
| HY-179155 | PI3K/mTOR-IN-19 | Inhibitor | / | Unkown |
| HY-178142 | Multi-kinase-IN-7 | Inhibitor | / | Unkown |
| HY-181675 | CHNQD-01522 | Activator | / | Unkown |
| HY-N0831R | Jaceosidin (Standard) | Activator | / | Unkown |
| HY-175588 | EGFR-IN-170 | / | Unkown | |
| HY-181837 | IKKβ-IN-7 | Modulator | / | Unkown |
| HY-119408 | MB725 | Activator | / | Unkown |
| HY-182360 | Cytisine-platinum(IV) prodrug-1 | / | Unkown | |
| HY-180823 | Topoisomerase II/EGFR-IN-2 | Inhibitor | / | Unkown |
| HY-183327 | PI3K/mTOR-IN-22 | / | Unkown | |
| HY-181174 | Antioxidant agent-22 | / | Unkown | |
| HY-P3148 | Astin B | Modulator | 95.0% | Unkown |
| HY-116267 | MHY219 | / | Unkown | |
| HY-174469 | PROTAC PI3K/110β degrader-2 | Inhibitor | / | Unkown |
| HY-108919 | CG-1521 | Inhibitor | 95.71% | Unkown |
| HY-119682 | Bax agonist 1 | / | Unkown | |
| HY-122481 | Thaspine acetate | / | Unkown | |
| HY-N8508 | Myrothecine A | Inducer | / | Unkown |
| HY-N15466 | Longan cerebroside II | / | Unkown |
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